Crosslinked linear polyethylenimine enhances delivery of DNA to the cytoplasm

Journal of Controlled Release

Volumn 167, Issue 1, 2013, Pages 101-107

  Bonner, Daniel K ^a,b,c   Zhao, Xiaoyong ^a,b   Buss, Hilda ^a,b   Langer, Robert ^a,b,c   Hammond, Paula T ^a,b  

^a Massachusetts Institute of Technology Cambridge   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c HARVARD MIT DIVISION OF HEALTH SCIENCES AND TECHNOLOGY   (United States)

Author keywords

Bioresponsive; Endosomal escape; Gene delivery; Polyethylenimine; Reducible

Indexed keywords

BIORESPONSIVE; ENDOSOMAL ESCAPES; GENE DELIVERY; POLYETHYLENIMINES; REDUCIBLE;

CELL MEMBRANES; CYTOLOGY; DRUG THERAPY; EFFICIENCY; GENE TRANSFER; MOLECULAR BIOLOGY; SULFUR COMPOUNDS;

POLYMERS;

CROSSLINKED LINEAR POLYETHYLENIMINE; DISULFIDE; POLYETHYLENEIMINE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; CYTOPLASM; DRUG CYTOTOXICITY; GENE DELIVERY SYSTEM; GENE TARGETING; GENETIC TRANSFECTION; PRIORITY JOURNAL;

CELL LINE, TUMOR; CELL SURVIVAL; CROSS-LINKING REAGENTS; CYTOPLASM; DNA; ENDOSOMES; HUMANS; PLASMIDS; POLYETHYLENEIMINE; TRANSFECTION;

EID: 84875370131     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2012.09.004     Document Type: Article

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