메뉴 건너뛰기




Volumn 18, Issue 1-2, 2013, Pages 75-95

Cell fusion in myeloma marrow microenvironment: Role in tumor progression

Author keywords

Aneuploidy; Cell fusion; Chromosomal instability; Multiple myeloma; Osteoclastogenesis

Indexed keywords

ANAPHASE PROMOTING COMPLEX; AURORA A KINASE; COLLAGEN TYPE 4; FIBROBLAST GROWTH FACTOR 2; GELATINASE A; GELATINASE B; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 11; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; MACROPHAGE INFLAMMATORY PROTEIN 1; MONOCYTE CHEMOTACTIC PROTEIN 1; OSTEOPROTEGERIN; PHOSPHATIDYLINOSITOL 3 KINASE; POLO LIKE KINASE; SCATTER FACTOR; SOMATOMEDIN C; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2;

EID: 84875359439     PISSN: 08939675     EISSN: 21626448     Source Type: Journal    
DOI: 10.1615/CritRevOncog.v18.i1-2.50     Document Type: Article
Times cited : (3)

References (124)
  • 1
    • 0031920620 scopus 로고    scopus 로고
    • Remarkable placenta
    • Benirschke K. Remarkable placenta. Clin Anat. 1998;11(3):194-205.
    • (1998) Clin Anat. , vol.11 , Issue.3 , pp. 194-205
    • Benirschke, K.1
  • 2
    • 0036128995 scopus 로고    scopus 로고
    • Muscle differentiation: How two cells become one
    • Taylor MV. Muscle differentiation: how two cells become one. Curr Biol. 2002;12(6):R224-8.
    • (2002) Curr Biol. , vol.12 , Issue.6
    • Taylor, M.V.1
  • 3
    • 0033988291 scopus 로고    scopus 로고
    • Multinucleated giant cells
    • Anderson JM. Multinucleated giant cells. Curr Opin Hematol. 2000;7(1):40-7.
    • (2000) Curr Opin Hematol. , vol.7 , Issue.1 , pp. 40-47
    • Anderson, J.M.1
  • 4
    • 17144455288 scopus 로고
    • Vestn Akad Med Nauk
    • Mekler LB. Vestn Akad Med Nauk SSSR. 1971;26(8):80-9.
    • (1971) SSSR , vol.26 , Issue.8 , pp. 80-89
    • Mekler, L.B.1
  • 5
    • 0037464559 scopus 로고    scopus 로고
    • Stem cells: Fusion brings down barriers
    • Medvinsky A, Smith A. Stem cells: Fusion brings down barriers. Nature. 2003;422(6934):823-5.
    • (2003) Nature. , vol.422 , Issue.6934 , pp. 823-825
    • Medvinsky, A.1    Smith, A.2
  • 6
    • 0842320021 scopus 로고    scopus 로고
    • Cell fusion: A hidden enemy?
    • Duelli D, Lazebnik Y. Cell fusion: A hidden enemy? Cancer Cell. 2003;3(5):445-448.
    • (2003) Cancer Cell. , vol.3 , Issue.5 , pp. 445-448
    • Duelli, D.1    Lazebnik, Y.2
  • 7
    • 0023854329 scopus 로고
    • Spontaneous fusion between metastatic mammary tumor subpopulations
    • Miller FR, McInerney D, Rogers C, Miller BE. Spontaneous fusion between metastatic mammary tumor subpopulations. J Cell Biochem. 1988;36(2):129-36.
    • (1988) J Cell Biochem. , vol.36 , Issue.2 , pp. 129-136
    • Miller, F.R.1    McInerney, D.2    Rogers, C.3    Miller, B.E.4
  • 8
    • 15244340908 scopus 로고    scopus 로고
    • The role of viruses in cell fusion and its importance to evolution, invasion and metastasis of cancer clones
    • Parris GE. The role of viruses in cell fusion and its importance to evolution, invasion and metastasis of cancer clones. Med Hypotheses. 2005;64(5):1,011-4.
    • (2005) Med Hypotheses. , vol.64 , Issue.5 , pp. 1011-1014
    • Parris, G.E.1
  • 9
    • 36448937162 scopus 로고    scopus 로고
    • Cell-to-cell fusion as a link between viruses and cancer
    • Duelli D, Lazebnik Y. Cell-to-cell fusion as a link between viruses and cancer. Nat Rev Cancer. 2007;7(12):968-76.
    • (2007) Nat Rev Cancer. , vol.7 , Issue.12 , pp. 968-976
    • Duelli, D.1    Lazebnik, Y.2
  • 10
    • 0016139097 scopus 로고
    • In vivo hybridisation of human tumour and normal hamster cells
    • Goldenberg DM, Pavia RA, Tsao MC. In vivo hybridisation of human tumour and normal hamster cells. Nature. 1974;250(5468):649-51.
    • (1974) Nature. , vol.250 , Issue.5468 , pp. 649-651
    • Goldenberg, D.M.1    Pavia, R.A.2    Tsao, M.C.3
  • 11
    • 0025673935 scopus 로고
    • Enhanced lung colonization and tumorigenicity of fused cells isolated from primary MCA tumors
    • Fortuna MB, Dewey MJ, Furmanski P. Enhanced lung colonization and tumorigenicity of fused cells isolated from primary MCA tumors. Cancer Lett. 1990;55(2):109-14.
    • (1990) Cancer Lett. , vol.55 , Issue.2 , pp. 109-114
    • Fortuna, M.B.1    Dewey, M.J.2    Furmanski, P.3
  • 12
    • 0016190166 scopus 로고
    • Asynchronous DNA synthesis and asynchronous mitosis in multinuclear ovarian cancer cells
    • Sheehy PF, Wakonig-Vaartaja T, Winn R, Clarkson BD. Asynchronous DNA synthesis and asynchronous mitosis in multinuclear ovarian cancer cells. Cancer Res. 1974;34(5):991-6.
    • (1974) Cancer Res. , vol.34 , Issue.5 , pp. 991-996
    • Sheehy, P.F.1    Wakonig-Vaartaja, T.2    Winn, R.3    Clarkson, B.D.4
  • 13
    • 0017224829 scopus 로고
    • Premature chromosome condensation in human leukemia
    • Williams DM, Scott CD, Beck TM. Premature chromosome condensation in human leukemia. Blood. 1976;47(4):687-93.
    • (1976) Blood. , vol.47 , Issue.4 , pp. 687-693
    • Williams, D.M.1    Scott, C.D.2    Beck, T.M.3
  • 14
    • 19044366706 scopus 로고    scopus 로고
    • Donor Y chromosome in renal carcinoma cells of a female BMT recipient: Visualization of putative BMT-tumor hybrids by FISH
    • Yilmaz Y, Lazova R, Qumsiyeh M, Cooper D, Pawelek J. Donor Y chromosome in renal carcinoma cells of a female BMT recipient: visualization of putative BMT-tumor hybrids by FISH. Bone Marrow Transplant. 2005;35(10):1,021-4.
    • (2005) Bone Marrow Transplant. , vol.35 , Issue.10 , pp. 1021-1024
    • Yilmaz, Y.1    Lazova, R.2    Qumsiyeh, M.3    Cooper, D.4    Pawelek, J.5
  • 15
    • 42549167207 scopus 로고    scopus 로고
    • Fusion of tumour cells with bone marrow-derived cells: A unifying explanation for metastasis
    • Pawelek JM, Chakraborty AK. Fusion of tumour cells with bone marrow-derived cells: a unifying explanation for metastasis. Nat Rev Cancer. 2008;8(5):377-86.
    • (2008) Nat Rev Cancer. , vol.8 , Issue.5 , pp. 377-386
    • Pawelek, J.M.1    Chakraborty, A.K.2
  • 16
    • 0000258464 scopus 로고
    • Characteristics of "hybrid"-type clonal cell lines obtained from mixed cultures in vitro
    • Barski G, Cornefert F. Characteristics of "hybrid"-type clonal cell lines obtained from mixed cultures in vitro. J Natl Cancer Inst. 1962;28:801-21.
    • (1962) J Natl Cancer Inst. , vol.28 , pp. 801-821
    • Barski, G.1    Cornefert, F.2
  • 17
    • 85047690508 scopus 로고    scopus 로고
    • Opinion: The origin of the cancer stem cell: Current controversies and new insights
    • Bjerkvig R, Tysnes BB, Aboody KS, Najbauer J, Terzis AJ. Opinion: the origin of the cancer stem cell: current controversies and new insights. Nat Rev Cancer. 2005;5(11):899-904.
    • (2005) Nat Rev Cancer. , vol.5 , Issue.11 , pp. 899-904
    • Bjerkvig, R.1    Tysnes, B.B.2    Aboody, K.S.3    Najbauer, J.4    Terzis, A.J.5
  • 18
    • 56849131881 scopus 로고    scopus 로고
    • The cancer cell-leukocyte fusion theory of metastasis
    • Pawelek JM, Chakraborty AK. The cancer cell-leukocyte fusion theory of metastasis. Adv Cancer Res. 2008;101:397-444.
    • (2008) Adv Cancer Res. , vol.101 , pp. 397-444
    • Pawelek, J.M.1    Chakraborty, A.K.2
  • 22
    • 79952781038 scopus 로고    scopus 로고
    • Multiple myeloma
    • Palumbo A, Anderson KC. Multiple myeloma. NEJM. 2011;364(11):1046-1060.
    • (2011) NEJM. , vol.364 , Issue.11 , pp. 1046-1060
    • Palumbo, A.1    Anderson, K.C.2
  • 23
    • 78649640378 scopus 로고    scopus 로고
    • The hemopoietic stem cell niche versus the microenvironment of the multiple myeloma-tumor initiating cell
    • Zipori D. The hemopoietic stem cell niche versus the microenvironment of the multiple myeloma-tumor initiating cell. Cancer Microenviron. 2010; 3(1):15-28.
    • (2010) Cancer Microenviron. , vol.3 , Issue.1 , pp. 15-28
    • Zipori, D.1
  • 24
    • 14944362858 scopus 로고    scopus 로고
    • Regulation of plasma-cell development
    • Shapiro-Shelef M, Calame K. Regulation of plasma-cell development. Nat Rev Immunol. 2005;5(3):230-42.
    • (2005) Nat Rev Immunol. , vol.5 , Issue.3 , pp. 230-242
    • Shapiro-Shelef, M.1    Calame, K.2
  • 26
    • 77956619675 scopus 로고    scopus 로고
    • Adhesion molecules: The lifelines of multiple myeloma cells
    • Katz BZ. Adhesion molecules: the lifelines of multiple myeloma cells. Semin Cancer Biol. 2010;20(3):186-95.
    • (2010) Semin Cancer Biol. , vol.20 , Issue.3 , pp. 186-195
    • Katz, B.Z.1
  • 27
    • 27144529975 scopus 로고    scopus 로고
    • The role of the bone marrow microenvironment in multiple myeloma
    • De Raeve HR, Vanderkerken K. The role of the bone marrow microenvironment in multiple myeloma. Histol Histopathol. 2005;20(4):1,227-50.
    • (2005) Histol Histopathol. , vol.20 , Issue.4 , pp. 1227-1250
    • de Raeve, H.R.1    Vanderkerken, K.2
  • 29
    • 0034655957 scopus 로고    scopus 로고
    • Vascular endothelial growth factor and interleukin-6 in paracrine tumor-stromal cell interactions in multiple myeloma
    • Dankbar B, Padró T, Leo R, Feldmann B, Kropff M, Mesters RM, Serve H, Berdel WE, Kienast J. Vascular endothelial growth factor and interleukin-6 in paracrine tumor-stromal cell interactions in multiple myeloma. Blood. 2000;95(8):2,630-6.
    • (2000) Blood. , vol.95 , Issue.8 , pp. 2630-2636
    • Dankbar, B.1    Padró, T.2    Leo, R.3    Feldmann, B.4    Kropff, M.5    Mesters, R.M.6    Serve, H.7    Berdel, W.E.8    Kienast, J.9
  • 30
    • 0030041147 scopus 로고    scopus 로고
    • Multiple myeloma cell adhesion-induced interleukin-6 expression in bone marrow stromal cells involves activation of NF-kappa B
    • Chauhan D, Uchiyama H, Akbarali Y, Urashima M, Yamamoto K, Libermann TA, Anderson KC. Multiple myeloma cell adhesion-induced interleukin-6 expression in bone marrow stromal cells involves activation of NF-kappa B. Blood. 1996;87(3):1,104-12.
    • (1996) Blood. , vol.87 , Issue.3 , pp. 1104-1112
    • Chauhan, D.1    Uchiyama, H.2    Akbarali, Y.3    Urashima, M.4    Yamamoto, K.5    Libermann, T.A.6    Anderson, K.C.7
  • 31
    • 0035921689 scopus 로고    scopus 로고
    • Biologic sequelae of interleukin-6 induced PI3-K/Akt signaling in multiple myeloma
    • Hideshima T, Nakamura N, Chauhan D, Anderson KC. Biologic sequelae of interleukin-6 induced PI3-K/Akt signaling in multiple myeloma. Oncogene. 2001;20(42):5,991-6,000.
    • (2001) Oncogene. , vol.20 , Issue.42 , pp. 5991-6000
    • Hideshima, T.1    Nakamura, N.2    Chauhan, D.3    Anderson, K.C.4
  • 32
    • 0024393839 scopus 로고
    • Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130
    • Taga T, Hibi M, Hirata Y, Yamasaki K, Yasukawa K, Matsuda T, Hirano T, Kishimoto T. Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130. Cell. 1989;58(3):573-81.
    • (1989) Cell. , vol.58 , Issue.3 , pp. 573-581
    • Taga, T.1    Hibi, M.2    Hirata, Y.3    Yamasaki, K.4    Yasukawa, K.5    Matsuda, T.6    Hirano, T.7    Kishimoto, T.8
  • 38
    • 0035102346 scopus 로고    scopus 로고
    • The bone marrow stromal microenvironment influences myeloma therapeutic response in vitro
    • Cheung WC, Van Ness B. The bone marrow stromal microenvironment influences myeloma therapeutic response in vitro. Leukemia. 2001;15(2):264-71.
    • (2001) Leukemia. , vol.15 , Issue.2 , pp. 264-271
    • Cheung, W.C.1    van Ness, B.2
  • 39
    • 0032450975 scopus 로고    scopus 로고
    • Interdependence between cytokines and cell adhesion molecules to induce interleukin-6 production by stromal cells in myeloma
    • Thomas X, Anglaret B, Magaud JP, Epstein J, Archimbaud E. Interdependence between cytokines and cell adhesion molecules to induce interleukin-6 production by stromal cells in myeloma. Leuk Lymphoma. 1998;32(1-2):107-19.
    • (1998) Leuk Lymphoma. , vol.32 , Issue.1-2 , pp. 107-119
    • Thomas, X.1    Anglaret, B.2    Magaud, J.P.3    Epstein, J.4    Archimbaud, E.5
  • 40
    • 77955804238 scopus 로고    scopus 로고
    • Expression and function of toll-like receptors in multiple myeloma patients: Toll-like receptors ligands promote multiple myeloma cell growth and survival via activation of nucler factor-kappaB
    • Xu Y, Zhao Y, Huang H, Chen G, Wu X, Wang Y, Chang W, Zhu Z, Feng Y, Wu D. Expression and function of toll-like receptors in multiple myeloma patients: toll-like receptors ligands promote multiple myeloma cell growth and survival via activation of nucler factor-kappaB. Br J Haematol. 2010;150(5):543-53.
    • (2010) Br J Haematol. , vol.150 , Issue.5 , pp. 543-553
    • Xu, Y.1    Zhao, Y.2    Huang, H.3    Chen, G.4    Wu, X.5    Wang, Y.6    Chang, W.7    Zhu, Z.8    Feng, Y.9    Wu, D.10
  • 44
    • 77952493512 scopus 로고    scopus 로고
    • Bone marrow microenvironment in myelomagenesis: Its potential role in early diagnosis
    • Balakumaran A, Robey PG, Fedarko N, Landgren O. Bone marrow microenvironment in myelomagenesis: its potential role in early diagnosis. Expert Rev Mol Diagn. 2010;10(4):465-80.
    • (2010) Expert Rev Mol Diagn. , vol.10 , Issue.4 , pp. 465-480
    • Balakumaran, A.1    Robey, P.G.2    Fedarko, N.3    Landgren, O.4
  • 45
    • 62649169258 scopus 로고    scopus 로고
    • Altered expression of fibronectin and collagens I and IV in multiple myeloma and monoclonal gammopathy of undetermined significance
    • Tancred TM, Belch AR, Reiman T, Pilarski LM, Kirshner J. Altered expression of fibronectin and collagens I and IV in multiple myeloma and monoclonal gammopathy of undetermined significance. J Histochem Cytochem. 2009;57(3):239-47.
    • (2009) J Histochem Cytochem. , vol.57 , Issue.3 , pp. 239-247
    • Tancred, T.M.1    Belch, A.R.2    Reiman, T.3    Pilarski, L.M.4    Kirshner, J.5
  • 46
    • 33746257305 scopus 로고    scopus 로고
    • Importance of the bone marrow microenvironment in inducing the angiogenic response in multiple myeloma
    • Ribatti D, Nico B, Vacca A. Importance of the bone marrow microenvironment in inducing the angiogenic response in multiple myeloma. Oncogene. 2006;25(31):4,257-66.
    • (2006) Oncogene. , vol.25 , Issue.31 , pp. 4257-4266
    • Ribatti, D.1    Nico, B.2    Vacca, A.3
  • 48
    • 31444447073 scopus 로고    scopus 로고
    • Bone marrow angiogenesis in multiple myeloma
    • Vacca A, Ribatti D. Bone marrow angiogenesis in multiple myeloma. Leukemia. 2006;20(2):193-9.
    • (2006) Leukemia. , vol.20 , Issue.2 , pp. 193-199
    • Vacca, A.1    Ribatti, D.2
  • 50
    • 0035892109 scopus 로고    scopus 로고
    • Dendritic cells from patients with myeloma are numerically normal but functionally defective as they fail to up-regulate CD80(B7-1) expression after huCD40LT stimulation because of inhibition by transforming growth factor-beta1 and interleukin-10
    • Brown RD, Pope B, Murray A, Esdale W, Sze DM, Gibson J, Ho PJ, Hart D, Joshua D. Dendritic cells from patients with myeloma are numerically normal but functionally defective as they fail to up-regulate CD80(B7-1) expression after huCD40LT stimulation because of inhibition by transforming growth factor-beta1 and interleukin-10. Blood. 2001;98(19):2,992-8.
    • (2001) Blood. , vol.98 , Issue.19 , pp. 2992-2998
    • Brown, R.D.1    Pope, B.2    Murray, A.3    Esdale, W.4    Sze, D.M.5    Gibson, J.6    Ho, P.J.7    Hart, D.8    Joshua, D.9
  • 51
    • 0031961959 scopus 로고    scopus 로고
    • B-lymphocyte suppression in multiple myeloma is a reversible phenomenon specific to normal B-cell progenitors and plasma cell precursors
    • Rawstron AC, Davies FE, Owen RG, English A, Pratt G, Child JA, Jack AS, Morgan GJ. B-lymphocyte suppression in multiple myeloma is a reversible phenomenon specific to normal B-cell progenitors and plasma cell precursors. Br J Haematol. 1998;100(1):176-83.
    • (1998) Br J Haematol. , vol.100 , Issue.1 , pp. 176-183
    • Rawstron, A.C.1    Davies, F.E.2    Owen, R.G.3    English, A.4    Pratt, G.5    Child, J.A.6    Jack, A.S.7    Morgan, G.J.8
  • 54
    • 78149270433 scopus 로고    scopus 로고
    • Increased level of both CD4+FOXP3+ regulatory T cells and CD14+HLA-DR-/low myeloid-derived suppressor cells and decreased level of dendritic cells in patients with multiple myeloma
    • Brimnes MK, Vangsted AJ, Knudsen LM, Gimsing P, Gang AO, Johnsen HE, Svane IM. Increased level of both CD4+FOXP3+ regulatory T cells and CD14+HLA-DR-/low myeloid-derived suppressor cells and decreased level of dendritic cells in patients with multiple myeloma. Scand J Immunol. 2010;72(6):540-7.
    • (2010) Scand J Immunol. , vol.72 , Issue.6 , pp. 540-547
    • Brimnes, M.K.1    Vangsted, A.J.2    Knudsen, L.M.3    Gimsing, P.4    Gang, A.O.5    Johnsen, H.E.6    Svane, I.M.7
  • 55
    • 58849093606 scopus 로고    scopus 로고
    • CD4(+)CD25(+)FoxP3(+) regulatory T cells are increased whilst CD3(+)CD4(-)CD8(-) alphabeta TCR(+) double negative T cells are decreased in the peripheral blood of patients with multiple myeloma which correlates with disease burden
    • Feyler S, von Lilienfeld-Toal M, Jarmin S, Marles L, Rawstron A, Ashcroft AJ, Owen RG, Selby PJ, Cook G. CD4(+)CD25(+)FoxP3(+) regulatory T cells are increased whilst CD3(+)CD4(-)CD8(-) alphabeta TCR(+) double negative T cells are decreased in the peripheral blood of patients with multiple myeloma which correlates with disease burden. Br J Haematol. 2009;144(5):686-95.
    • (2009) Br J Haematol. , vol.144 , Issue.5 , pp. 686-695
    • Feyler, S.1    von Lilienfeld-Toal, M.2    Jarmin, S.3    Marles, L.4    Rawstron, A.5    Ashcroft, A.J.6    Owen, R.G.7    Selby, P.J.8    Cook, G.9
  • 56
    • 79958695591 scopus 로고    scopus 로고
    • Significantly reduced regulatory T cell population in patients with untreated multiple myeloma
    • Gupta R, Ganeshan P, Hakim M, Verma R, Sharma A, Kumar L. Significantly reduced regulatory T cell population in patients with untreated multiple myeloma. Leuk Res. 2011;35(7):874-8.
    • (2011) Leuk Res. , vol.35 , Issue.7 , pp. 874-878
    • Gupta, R.1    Ganeshan, P.2    Hakim, M.3    Verma, R.4    Sharma, A.5    Kumar, L.6
  • 57
    • 78149322663 scopus 로고    scopus 로고
    • A novel role of IL-17 producing lymphocytes in mediating lytic bone disease in multiple myeloma
    • Noonan K, Marchionni L, Anderson J, Pardoll D, Roodman GD, Borrello I. A novel role of IL-17 producing lymphocytes in mediating lytic bone disease in multiple myeloma. Blood. 2010;116(18):3,554-63.
    • (2010) Blood. , vol.116 , Issue.18 , pp. 3554-3563
    • Noonan, K.1    Marchionni, L.2    Anderson, J.3    Pardoll, D.4    Roodman, G.D.5    Borrello, I.6
  • 58
    • 53449089919 scopus 로고    scopus 로고
    • Dendritic cells mediate the induction of polyfunctional human IL17-producing cells (Th17-1 cells) enriched in the bone marrow of patients with myeloma
    • Dhodapkar KM, Barbuto S, Matthews P, Kukreja A, Mazumder A, Vesole D, Jagannath S, Dhodapkar MV. Dendritic cells mediate the induction of polyfunctional human IL17-producing cells (Th17-1 cells) enriched in the bone marrow of patients with myeloma. Blood. 2008;112(7):2878-85.
    • (2008) Blood. , vol.112 , Issue.7 , pp. 2878-2885
    • Dhodapkar, K.M.1    Barbuto, S.2    Matthews, P.3    Kukreja, A.4    Mazumder, A.5    Vesole, D.6    Jagannath, S.7    Dhodapkar, M.V.8
  • 59
    • 0345599884 scopus 로고    scopus 로고
    • Vigorous premalignancy-specific effector T cell response in the bone marrow of patients with monoclonal gammopathy
    • Dhodapkar MV, Krasovsky J, Osman K, Geller MD. Vigorous premalignancy-specific effector T cell response in the bone marrow of patients with monoclonal gammopathy. J Exp Med. 2003;198(11):1,753-7.
    • (2003) J Exp Med. , vol.198 , Issue.11 , pp. 1753-1757
    • Dhodapkar, M.V.1    Krasovsky, J.2    Osman, K.3    Geller, M.D.4
  • 60
    • 3042691752 scopus 로고    scopus 로고
    • Either interleukin-12 or interferon-gamma can correct the dendritic cell defect induced by transforming growth factor beta in patients with myeloma
    • Brown R, Murray A, Pope B, Sze DM, Gibson J, Ho PJ, Hart D, Joshua D. Either interleukin-12 or interferon-gamma can correct the dendritic cell defect induced by transforming growth factor beta in patients with myeloma. Br J Haematol. 2004;125(6):743-8.
    • (2004) Br J Haematol. , vol.125 , Issue.6 , pp. 743-748
    • Brown, R.1    Murray, A.2    Pope, B.3    Sze, D.M.4    Gibson, J.5    Ho, P.J.6    Hart, D.7    Joshua, D.8
  • 61
    • 70350710809 scopus 로고    scopus 로고
    • Dominant role of CD47-thrombospondin-1 interactions in myeloma-induced fusion of human dendritic cells: Implications for bone disease
    • Kukreja A, Radfar S, Sun BH, Insogna K, Dhodapkar MV. Dominant role of CD47-thrombospondin-1 interactions in myeloma-induced fusion of human dendritic cells: implications for bone disease. Blood. 2009;114(16):3,413-21.
    • (2009) Blood. , vol.114 , Issue.16 , pp. 3413-3421
    • Kukreja, A.1    Radfar, S.2    Sun, B.H.3    Insogna, K.4    Dhodapkar, M.V.5
  • 62
    • 63849262026 scopus 로고    scopus 로고
    • Bone-resorbing cells in multiple myeloma: Osteoclasts, myeloma cell polykaryons or both?
    • Silvestris F, Ciavarella S, De Matteo M, Tucci M, Dammacco F. Bone-resorbing cells in multiple myeloma: osteoclasts, myeloma cell polykaryons or both? Oncologist. 2009;14(3):264-75.
    • (2009) Oncologist. , vol.14 , Issue.3 , pp. 264-275
    • Silvestris, F.1    Ciavarella, S.2    de Matteo, M.3    Tucci, M.4    Dammacco, F.5
  • 63
    • 0037443533 scopus 로고    scopus 로고
    • RANK ligand and osteoprotegerin in myeloma bone disease
    • Sezer O, Heider U, Zavrski I, Kühne CA, Hofbauer LC. RANK ligand and osteoprotegerin in myeloma bone disease. Blood. 2003;101(6):2,094-8.
    • (2003) Blood. , vol.101 , Issue.6 , pp. 2094-2098
    • Sezer, O.1    Heider, U.2    Zavrski, I.3    Kühne, C.A.4    Hofbauer, L.C.5
  • 65
    • 4143119930 scopus 로고    scopus 로고
    • Impaired osteoblastogenesis in myeloma bone disease: Role of upregulated apoptosis by cytokines and malignant plasma cells
    • Silvestris F, Cafforio P, Calvani N, Dammacco F. Impaired osteoblastogenesis in myeloma bone disease: role of upregulated apoptosis by cytokines and malignant plasma cells. Br J Haematol. 2004;126(4):475-86.
    • (2004) Br J Haematol. , vol.126 , Issue.4 , pp. 475-486
    • Silvestris, F.1    Cafforio, P.2    Calvani, N.3    Dammacco, F.4
  • 67
    • 33845547969 scopus 로고    scopus 로고
    • The dendritic cell-specific transmembrane protein DC-STAMP is essential for osteoclast fusion and osteoclast bone-resorbing activity
    • Miyamoto T. The dendritic cell-specific transmembrane protein DC-STAMP is essential for osteoclast fusion and osteoclast bone-resorbing activity. Mod Rheumatol. 2006;16:341-2.
    • (2006) Mod Rheumatol. , vol.16 , pp. 341-342
    • Miyamoto, T.1
  • 69
    • 33748107509 scopus 로고    scopus 로고
    • Role of DC-STAMP in cellular fusion of osteoclasts and macrophage giant cells
    • Yagi M, Miyamoto T, Toyama Y, Suda T. Role of DC-STAMP in cellular fusion of osteoclasts and macrophage giant cells. J Bone Miner Metab. 2006;24:355-8.
    • (2006) J Bone Miner Metab. , vol.24 , pp. 355-358
    • Yagi, M.1    Miyamoto, T.2    Toyama, Y.3    Suda, T.4
  • 70
    • 59249086198 scopus 로고    scopus 로고
    • Functions and molecular mechanisms of the CD47-SIRPalpha signalling pathway
    • Matozaki T, Murata Y, Okazawa H, Ohnishi H. Functions and molecular mechanisms of the CD47-SIRPalpha signalling pathway. Trends Cell Biol. 2009;19:72-80.
    • (2009) Trends Cell Biol. , vol.19 , pp. 72-80
    • Matozaki, T.1    Murata, Y.2    Okazawa, H.3    Ohnishi, H.4
  • 74
    • 34548222168 scopus 로고    scopus 로고
    • Dendritic cells at the osteo-immune interface: Implications for inflammation-induced bone loss
    • Alnaeeli M, Park J, Mahamed D, Penninger JM, Teng YT. Dendritic cells at the osteo-immune interface: implications for inflammation-induced bone loss. J Bone Miner Res. 2007;22:775-80.
    • (2007) J Bone Miner Res. , vol.22 , pp. 775-780
    • Alnaeeli, M.1    Park, J.2    Mahamed, D.3    Penninger, J.M.4    Teng, Y.T.5
  • 76
    • 79960598123 scopus 로고    scopus 로고
    • Immature dendritic cells from patients with multiple myeloma are prone to osteoclast differentiation in vitro
    • Tucci M, Ciavarella S, Strippoli S, Brunetti O, Dammacco F, Silvestris F. Immature dendritic cells from patients with multiple myeloma are prone to osteoclast differentiation in vitro. Exp Hematol. 2011;39(7):773-83.
    • (2011) Exp Hematol. , vol.39 , Issue.7 , pp. 773-783
    • Tucci, M.1    Ciavarella, S.2    Strippoli, S.3    Brunetti, O.4    Dammacco, F.5    Silvestris, F.6
  • 77
    • 0021714773 scopus 로고
    • Suggestive evidence that the highly metastatic variant ESb of the T-cell lymphoma Eb is derived from spontaneous fusion with a host macrophage
    • Larizza L, Schirrmacher V, Graf L, Pflügler E, Peres-Martinez M, Stöhr M. Suggestive evidence that the highly metastatic variant ESb of the T-cell lymphoma Eb is derived from spontaneous fusion with a host macrophage. Int J Cancer. 1984;34:699-706.
    • (1984) Int J Cancer. , vol.34 , pp. 699-706
    • Larizza, L.1    Schirrmacher, V.2    Graf, L.3    Pflügler, E.4    Peres-Martinez, M.5    Stöhr, M.6
  • 78
    • 66349096703 scopus 로고    scopus 로고
    • Viewing malignant melanoma cells as macrophage-tumor hybrids
    • Pawelek JM. Viewing malignant melanoma cells as macrophage-tumor hybrids. Cell Adh Migr. 2007;1:2-6.
    • (2007) Cell Adh Migr. , vol.1 , pp. 2-6
    • Pawelek, J.M.1
  • 80
    • 75149120560 scopus 로고    scopus 로고
    • Myeloma cell-induced disruption of bone remodelling compartments leads to osteolytic lesions and generation of osteoclast-myeloma hybrid cells
    • Andersen TL, Søe K, Sondergaard TE, Plesner T, Delaisse JM. Myeloma cell-induced disruption of bone remodelling compartments leads to osteolytic lesions and generation of osteoclast-myeloma hybrid cells. Br J Haematol. 2010;148:551-61.
    • (2010) Br J Haematol. , vol.148 , pp. 551-561
    • Andersen, T.L.1    Søe, K.2    Sondergaard, T.E.3    Plesner, T.4    Delaisse, J.M.5
  • 82
  • 88
    • 27244441444 scopus 로고    scopus 로고
    • Functional osteoclast-like transformation of cultured human myeloma cell lines
    • Calvani N, Cafforio P, Silvestris F, Dammacco F. Functional osteoclast-like transformation of cultured human myeloma cell lines. Br J Haematol. 2005;130:926-38.
    • (2005) Br J Haematol. , vol.130 , pp. 926-938
    • Calvani, N.1    Cafforio, P.2    Silvestris, F.3    Dammacco, F.4
  • 89
    • 39049101272 scopus 로고    scopus 로고
    • Expression and function of the calcitonin receptor by myeloma cells in their osteoclast-like activity in vitro
    • Silvestris F, Cafforio P, De Matteo M, Quatraro C, Dammacco F. Expression and function of the calcitonin receptor by myeloma cells in their osteoclast-like activity in vitro. Leuk Res. 2008;32:611-23.
    • (2008) Leuk Res. , vol.32 , pp. 611-623
    • Silvestris, F.1    Cafforio, P.2    de Matteo, M.3    Quatraro, C.4    Dammacco, F.5
  • 90
    • 0037082473 scopus 로고    scopus 로고
    • Negative regulation of erythroblast maturation by Fas-L(+)/TRAIL(+) highly malignant plasma cells: A major pathogenetic mechanism of anemia in multiple myeloma
    • Silvestris F, Cafforio P, Tucci M, Dammacco F. Negative regulation of erythroblast maturation by Fas-L(+)/TRAIL(+) highly malignant plasma cells: a major pathogenetic mechanism of anemia in multiple myeloma. Blood. 2002;99(4):1,305-13.
    • (2002) Blood. , vol.99 , Issue.4 , pp. 1305-1313
    • Silvestris, F.1    Cafforio, P.2    Tucci, M.3    Dammacco, F.4
  • 91
    • 69249134137 scopus 로고    scopus 로고
    • β3 integrin subunit mediates the bone-resorbing function exerted by cultured myeloma plasma cells
    • Tucci M, De Palma R, Lombardi L, Rodolico G, Berrino L, Dammacco F, Silvestris F. β3 integrin subunit mediates the bone-resorbing function exerted by cultured myeloma plasma cells. Cancer Res. 2009;69(16):6,738-46.
    • (2009) Cancer Res. , vol.69 , Issue.16 , pp. 6738-6746
    • Tucci, M.1    de Palma, R.2    Lombardi, L.3    Rodolico, G.4    Berrino, L.5    Dammacco, F.6    Silvestris, F.7
  • 92
    • 28444486962 scopus 로고    scopus 로고
    • Reappraisal of the Hansemann-Boveri hypothesis on the origin of tumors
    • Hardy PA, Zacharias H. Reappraisal of the Hansemann-Boveri hypothesis on the origin of tumors. Cell Biol Int. 2005;29:983-92.
    • (2005) Cell Biol Int. , vol.29 , pp. 983-992
    • Hardy, P.A.1    Zacharias, H.2
  • 96
    • 33748190743 scopus 로고    scopus 로고
    • Integration of global SNP-based mapping and expression arrays reveals key regions, mechanisms and genes important in the pathogenesis of multiple myeloma
    • Walker BA, Leone PE, Jenner MW, Li C, Gonzalez D, Johnson DC, Ross FM, Davies FE, Morgan GJ. Integration of global SNP-based mapping and expression arrays reveals key regions, mechanisms and genes important in the pathogenesis of multiple myeloma. Blood. 2006;108:1,733-43.
    • (2006) Blood. , vol.108 , pp. 1733-1743
    • Walker, B.A.1    Leone, P.E.2    Jenner, M.W.3    Li, C.4    Gonzalez, D.5    Johnson, D.C.6    Ross, F.M.7    Davies, F.E.8    Morgan, G.J.9
  • 99
    • 70349902608 scopus 로고    scopus 로고
    • Centrosomes and myeloma; aneuploidy and proliferation
    • Chng WJ, Fonseca R. Centrosomes and myeloma; aneuploidy and proliferation. Environ Mol Mutag. 2009;50(8):697-707.
    • (2009) Environ Mol Mutag. , vol.50 , Issue.8 , pp. 697-707
    • Chng, W.J.1    Fonseca, R.2
  • 100
    • 27744448655 scopus 로고    scopus 로고
    • A primate virus generates transformed human cells by fusion
    • Duelli DM, Hearn S, Myers MP, Lazebnik Y. A primate virus generates transformed human cells by fusion. J Cell Biol. 2005;171:493-503.
    • (2005) J Cell Biol. , vol.171 , pp. 493-503
    • Duelli, D.M.1    Hearn, S.2    Myers, M.P.3    Lazebnik, Y.4
  • 102
    • 0035188129 scopus 로고    scopus 로고
    • Managing the centrosome numbers game: From chaos to stability in cancer cell division
    • Brinkley BR. Managing the centrosome numbers game: from chaos to stability in cancer cell division. Trends Cell Biol. 2001;11(1):18-21.
    • (2001) Trends Cell Biol. , vol.11 , Issue.1 , pp. 18-21
    • Brinkley, B.R.1
  • 103
    • 0037048280 scopus 로고    scopus 로고
    • Centrosome amplification and the development of cancer
    • D'Assoro AB, Lingle WL, Salisbury JL. Centrosome amplification and the development of cancer. Oncogene. 2002;21:6,146-53.
    • (2002) Oncogene. , vol.21 , pp. 6146-6153
    • D'Assoro, A.B.1    Lingle, W.L.2    Salisbury, J.L.3
  • 104
    • 0037288474 scopus 로고    scopus 로고
    • Chromosome instability in cancer: How, when, and why?
    • Gisselsson D. Chromosome instability in cancer: how, when, and why? Adv Cancer Res. 2003;87:1-29.
    • (2003) Adv Cancer Res. , vol.87 , pp. 1-29
    • Gisselsson, D.1
  • 108
    • 0037085787 scopus 로고    scopus 로고
    • Oncogenesis of multiple myeloma: 14q32 and 13q chromosomal abnormalities are not randomly distributed, but correlate with natural history, immunological features, and clinical presentations
    • Intergroupe Francophone du Myélome
    • Avet-Loiseau H, Facon T, Grosbois B, Magrangeas F, Rapp MJ, Harousseau JL, Minvielle S, Bataille R, Intergroupe Francophone du Myélome. Oncogenesis of multiple myeloma: 14q32 and 13q chromosomal abnormalities are not randomly distributed, but correlate with natural history, immunological features, and clinical presentations. Blood. 2002;99:2,185-91.
    • (2002) Blood. , vol.99 , pp. 2185-2191
    • Avet-Loiseau, H.1    Facon, T.2    Grosbois, B.3    Magrangeas, F.4    Rapp, M.J.5    Harousseau, J.L.6    Minvielle, S.7    Bataille, R.8
  • 110
    • 34247333444 scopus 로고    scopus 로고
    • The spindle-assembly checkpoint in space and time
    • Musacchio A, Salmon ED. The spindle-assembly checkpoint in space and time. Nature Rev Mol Cell Biol. 2007;8:379-93.
    • (2007) Nature Rev Mol Cell Biol. , vol.8 , pp. 379-393
    • Musacchio, A.1    Salmon, E.D.2
  • 112
    • 22244459880 scopus 로고    scopus 로고
    • Induction of apoptosis by an inhibitor of the mitotic kinesin KSP requires both activation of the spindle assembly checkpoint and mitotic slippage
    • Tao W, South VJ, Zhang Y, Davide JP, Farrell L, Kohl NE, Sepp-Lorenzino L, Lobell RB. Induction of apoptosis by an inhibitor of the mitotic kinesin KSP requires both activation of the spindle assembly checkpoint and mitotic slippage. Cancer Cell. 2005;8(1):49-59.
    • (2005) Cancer Cell. , vol.8 , Issue.1 , pp. 49-59
    • Tao, W.1    South, V.J.2    Zhang, Y.3    Davide, J.P.4    Farrell, L.5    Kohl, N.E.6    Sepp-Lorenzino, L.7    Lobell, R.B.8
  • 113
    • 33744996707 scopus 로고    scopus 로고
    • Mitotic checkpoint slippage in humans occurs via cyclin B destruction in the presence of an active checkpoint
    • Brito DA, Rieder CL. Mitotic checkpoint slippage in humans occurs via cyclin B destruction in the presence of an active checkpoint. Curr Biol. 2006;16:1,194-200.
    • (2006) Curr Biol. , vol.16 , pp. 1194-1200
    • Brito, D.A.1    Rieder, C.L.2
  • 116
    • 79960957085 scopus 로고    scopus 로고
    • Mitotic catastrophe: A mechanism for avoiding genomic instability
    • Vitale I, Galluzzi L, Castedo, Kroemer G. Mitotic catastrophe: a mechanism for avoiding genomic instability. Nat Rev Mol Cell Biol. 2011;12(6):385-92.
    • (2011) Nat Rev Mol Cell Biol. , vol.12 , Issue.6 , pp. 385-392
    • Vitale, I.1    Galluzzi, L.2    Castedo, K.G.3
  • 119
    • 0036468420 scopus 로고    scopus 로고
    • Centrosome composition and microtubule enchoring mechanisms
    • Bornens M. Centrosome composition and microtubule enchoring mechanisms. Curr Opin Cell Biol. 2002;14:25-34.
    • (2002) Curr Opin Cell Biol. , vol.14 , pp. 25-34
    • Bornens, M.1
  • 120
    • 0035266301 scopus 로고    scopus 로고
    • Centrosome defects can account for cellular and genetic changes that characterize prostate cancer progression
    • Pihan GA, Purohit A, Wallace J, Malhotra R, Liotta L, Doxsey SJ. Centrosome defects can account for cellular and genetic changes that characterize prostate cancer progression. Cancer Res. 2001;61:2,212-9.
    • (2001) Cancer Res. , vol.61 , pp. 2212-2219
    • Pihan, G.A.1    Purohit, A.2    Wallace, J.3    Malhotra, R.4    Liotta, L.5    Doxsey, S.J.6
  • 121
    • 0032539868 scopus 로고    scopus 로고
    • Centrosome hypertrophy in human breast tumors: Implications for genomic stability and cell polarity
    • Lingle WL, Lutz WH, Ingle JN, Maihle NJ, Salisbury JL. Centrosome hypertrophy in human breast tumors: implications for genomic stability and cell polarity. Proc Natl Acad Sci USA. 1998;95:2,950-5.
    • (1998) Proc Natl Acad Sci USA. , vol.95 , pp. 2950-2955
    • Lingle, W.L.1    Lutz, W.H.2    Ingle, J.N.3    Maihle, N.J.4    Salisbury, J.L.5
  • 122
    • 21744458439 scopus 로고    scopus 로고
    • Centrosome aberrations in chronic myeloid leukemia correlate with stage of disease and chromosomal instability
    • Giehl M, Fabarius A, Frank O, Hochhaus A, Hafner M, Hehlmann R, Seifarth W. Centrosome aberrations in chronic myeloid leukemia correlate with stage of disease and chromosomal instability. Leukemia. 2005;19:1,192-7.
    • (2005) Leukemia. , vol.19 , pp. 1192-1197
    • Giehl, M.1    Fabarius, A.2    Frank, O.3    Hochhaus, A.4    Hafner, M.5    Hehlmann, R.6    Seifarth, W.7
  • 123
    • 38949203768 scopus 로고    scopus 로고
    • The centrosome index is a powerful prognostic marker in myeloma and identifies a cohort of patients that may benefit from aurora kinase inhibition
    • Chng WJ, Braggio E, Mulligan G, Bryant B, Remstein E, Valdez R, Dogan A, Fonseca R. The centrosome index is a powerful prognostic marker in myeloma and identifies a cohort of patients that may benefit from aurora kinase inhibition. Blood. 2007;111:1,603-9.
    • (2007) Blood. , vol.111 , pp. 1603-1609
    • Chng, W.J.1    Braggio, E.2    Mulligan, G.3    Bryant, B.4    Remstein, E.5    Valdez, R.6    Dogan, A.7    Fonseca, R.8
  • 124
    • 13444294239 scopus 로고    scopus 로고
    • Receptor for hyaluronan-mediated motility correlates with centrosome abnormalities in multiple myeloma and maintains mitotic integrity
    • Maxwell CA, Keats JJ, Belch AR, Pilarski LM, Reiman T. Receptor for hyaluronan-mediated motility correlates with centrosome abnormalities in multiple myeloma and maintains mitotic integrity. Cancer Res. 2005;65:850-60.
    • (2005) Cancer Res. , vol.65 , pp. 850-860
    • Maxwell, C.A.1    Keats, J.J.2    Belch, A.R.3    Pilarski, L.M.4    Reiman, T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.