-
1
-
-
0033490051
-
The intracellular hyaluronan receptor RHAMM/IHABP interacts with microtubules and actin filaments
-
Assmann V, Jenkinson D, Marshall JF, Hart IR. 1999. The intracellular hyaluronan receptor RHAMM/IHABP interacts with microtubules and actin filaments. J Cell Sci 112(Pt 22):3943-3954. (Pubitemid 30119764)
-
(1999)
Journal of Cell Science
, vol.112
, Issue.22
, pp. 3943-3954
-
-
Assmann, V.1
Jenkinson, D.2
Marshall, J.F.3
Hart, I.R.4
-
2
-
-
0037370476
-
The genetics and genomics of cancer
-
Balmain A, Gray J, Ponder B. 2003. The genetics and genomics of cancer. Nat Genet 33(Suppl):238-244.
-
(2003)
Nat Genet
, vol.33
, Issue.SUPPL.
, pp. 238-244
-
-
Balmain, A.1
Gray, J.2
Ponder, B.3
-
3
-
-
0345060052
-
Recapitulation of the Effects of the Human Papillomavirus Type 16 E7 Oncogene on Mouse Epithelium by Somatic Rb Deletion and Detection of pRb-Independent Effects of E7 in Vivo
-
DOI 10.1128/MCB.23.24.9094-9103.2003
-
Balsitis SJ, Sage J, Duensing S, Munger K, Jacks T, Lambert PF. 2003. Recapitulation of the effects of the human papillomavirus type 16 E7 oncogene on mouse epithelium by somatic Rb deletion and detection of pRb-independent effects of E7 in vivo. Mol Cell Biol 23:9094-9103. (Pubitemid 37499799)
-
(2003)
Molecular and Cellular Biology
, vol.23
, Issue.24
, pp. 9094-9103
-
-
Balsitis, S.J.1
Sage, J.2
Duensing, S.3
Munger, K.4
Jacks, T.5
Lambert, P.F.6
-
4
-
-
22044440425
-
Cyclin D dysregulation: An early and unifying pathogenic event in multiple myeloma
-
DOI 10.1182/blood-2005-01-0034
-
Bergsagel PL, Kuehl WM, Zhan F, Sawyer J, Barlogie B, Shaughnessy J Jr. 2005. Cyclin D dysregulation: An early and unifying pathogenic event in multiple myeloma. Blood 106:296-303. (Pubitemid 40967205)
-
(2005)
Blood
, vol.106
, Issue.1
, pp. 296-303
-
-
Bergsagel, P.L.1
Kuehl, W.M.2
Zhan, F.3
Sawyer, J.4
Barlogie, B.5
Shaughnessy Jr., J.6
-
5
-
-
22944488871
-
Telomeres and human disease: Ageing, cancer and beyond
-
DOI 10.1038/nrg1656
-
Blasco MA. 2005. Telomeres and human disease: Ageing, cancer and beyond. Nat Rev Genet 6:611-622. (Pubitemid 41044298)
-
(2005)
Nature Reviews Genetics
, vol.6
, Issue.8
, pp. 611-622
-
-
Blasco, M.A.1
-
6
-
-
0036468420
-
Centrosome composition and microtubule anchoring mechanisms
-
DOI 10.1016/S0955-0674(01)00290-3
-
Bornens M. 2002. Centrosome composition and microtubule anchoring mechanisms. Curr Opin Cell Biol 14:25-34. (Pubitemid 34131653)
-
(2002)
Current Opinion in Cell Biology
, vol.14
, Issue.1
, pp. 25-34
-
-
Bornens, M.1
-
7
-
-
0032546360
-
Mutations of mitotic checkpoint genes in human cancers
-
DOI 10.1038/32688
-
Cahill DP, Lengauer C, Yu J, Riggins GJ, Willson JK, Markowitz SD, Kinzler KW, Vogelstein B. 1998. Mutations of mitotic checkpoint genes in human cancers. Nature 392:300-303. (Pubitemid 28155105)
-
(1998)
Nature
, vol.392
, Issue.6673
, pp. 300-303
-
-
Cahill, D.P.1
Lengauer, C.2
Yu, J.3
Riggins, G.J.4
Willson, J.K.V.5
Markowitz, S.D.6
Kinzler, K.W.7
Vogelstein, B.8
-
9
-
-
0032212243
-
The t(4;14) translocation in myeloma dysregulates both FGFR3 and a novel gene, MMSET, resulting in IgH/MMSET hybrid transcripts
-
Chesi M, Nardini E, Lim RS, Smith KD, Kuehl WM, Bergsagel PL. 1998. The t(4;14) translocation in myeloma dysregulates both FGFR3 and a novel gene, MMSET, resulting in IgH/MMSET hybrid transcripts. Blood 92:3025-3034. (Pubitemid 28492306)
-
(1998)
Blood
, vol.92
, Issue.9
, pp. 3025-3034
-
-
Chesi, M.1
Nardini, E.2
Lim, R.S.C.3
Smith, K.D.4
Michael Kuehl, W.5
Bergsagel, P.L.6
-
10
-
-
24744434736
-
A validated FISH trisomy index demonstrates the hyperdiploid and nonhyperdiploid dichotomy in MGUS
-
DOI 10.1182/blood-2005-02-0761
-
Chng WJ, Van Wier SA, Ahmann GJ, Winkler JM, Jalal SM, Bergsagel PL, Chesi M, Trendle MC, Oken MM, Blood E, Henderson K, Santana-Davila R, Kyle RA, Gertz MA, Lacy MQ, Dispenzieri A, Greipp PR, Fonseca R. 2005. A validated FISH trisomy index demonstrates the hyperdiploid and nonhyperdiploid dichotomy in MGUS. Blood 106:2156-2161. (Pubitemid 41291733)
-
(2005)
Blood
, vol.106
, Issue.6
, pp. 2156-2161
-
-
Chng, W.J.1
Van Wier, S.A.2
Ahmann, G.J.3
Winkler, J.M.4
Jalal, S.M.5
Bergsagel, P.L.6
Chesi, M.7
Trendle, M.C.8
Oken, M.M.9
Blood, E.10
Henderson, K.11
Santana-Davila, R.12
Kyle, R.A.13
Gertz, M.A.14
Lacy, M.Q.15
Dispenzieri, A.16
Greipp, P.R.17
Fonseca, R.18
-
11
-
-
33646402309
-
Clinical implication of centrosome amplification in plasma cell neoplasm
-
Chng WJ, Ahmann GJ, Henderson K, Santana-Davila R, Greipp PR, Gertz MA, Lacy MQ, Dispenzieri A, Kumar S, Rajkumar SV, Lust JA, Kyle RA, Zeldenrust SR, Hayman SR, Fonseca R. 2006. Clinical implication of centrosome amplification in plasma cell neoplasm. Blood 107:3669-3675.
-
(2006)
Blood
, vol.107
, pp. 3669-3675
-
-
Chng, W.J.1
Ahmann, G.J.2
Henderson, K.3
Santana-Davila, R.4
Greipp, P.R.5
Gertz, M.A.6
Lacy, M.Q.7
Dispenzieri, A.8
Kumar, S.9
Rajkumar, S.V.10
Lust, J.A.11
Kyle, R.A.12
Zeldenrust, S.R.13
Hayman, S.R.14
Fonseca, R.15
-
12
-
-
38949203768
-
The centrosome index is a powerful prognostic marker in myeloma and identifies a cohort of patients that might benefit from aurora kinase inhibition
-
DOI 10.1182/blood-2007-06-097774
-
Chng WJ, Braggio E, Mulligan G, Bryant B, Remstein E, Valdez R, Dogan A, Fonseca R. 2007. The centrosome index is a powerful prognostic marker in myeloma and identifies a cohort of patients that may benefit from aurora kinase inhibition. Blood. (Pubitemid 351213451)
-
(2008)
Blood
, vol.111
, Issue.3
, pp. 1603-1609
-
-
Chng, W.J.1
Braggio, E.2
Mulligan, G.3
Bryant, B.4
Remstein, E.5
Valdez, R.6
Dogan, A.7
Fonseca, R.8
-
13
-
-
0033104710
-
Overexpression of the receptor for hyaluronan-mediated motility (RHAMM) characterizes the malignant clone in multiple myeloma: Identification of three distinct RHAMM variants
-
Crainie M, Belch AR, Mant MJ, Pilarski LM. 1999. Overexpression of the receptor for hyaluronan-mediated motility (RHAMM) characterizes the malignant clone in multiple myeloma: Identification of three distinct RHAMM variants. Blood 93:1684-1696. (Pubitemid 29102497)
-
(1999)
Blood
, vol.93
, Issue.5
, pp. 1684-1696
-
-
Crainie, M.1
Belch, A.R.2
Mant, M.J.3
Pilarski, L.M.4
-
14
-
-
34248359128
-
Paradoxical expression of INK4c in proliferative multiple myeloma tumors: Bi-allelic deletion vs increased expression
-
DOI 10.1186/1747-1028-1-23
-
Dib A, Peterson TR, Raducha-Grace L, Zingone A, Zhan F, Hanamura I, Barlogie B, Shaughnessy J Jr, Kuehl WM. 2006. Paradoxical expression of INK4c in proliferative multiple myeloma tumors: Bi-allelic deletion vs increased expression. Cell Div 1:23. (Pubitemid 46731034)
-
(2006)
Cell Division
, vol.1
, pp. 23
-
-
Dib, A.1
Peterson, T.R.2
Raducha-Grace, L.3
Zingone, A.4
Zhan, F.5
Hanamura, I.6
Barlogie, B.7
Shaughnessy Jr., J.8
Kuehl, W.M.9
-
15
-
-
33846878522
-
Methylation and expression of the p16INK4A tumor suppressor gene in multiple myeloma [5]
-
DOI 10.1182/blood-2006-09-049510
-
Dib A, Barlogie B, Shaughnessy JD Jr, Kuehl WM. 2007. Methylation and expression of the p16INK4A tumor suppressor gene in multiple myeloma. Blood 109:1337-1338. (Pubitemid 46220692)
-
(2007)
Blood
, vol.109
, Issue.3
, pp. 1337-1338
-
-
Dib, A.1
Barlogie, B.2
Shaughnessy Jr., J.D.3
Kuehl, W.M.4
-
16
-
-
0034730196
-
The human papillomavirus type 16 E6 and E7 oncoproteins cooperate to induce mitotic defects and genomic instability by uncoupling centrosome duplication from the cell division cycle
-
Duensing S, Lee LY, Duensing A, Basile J, Piboonniyom S, Gonzalez S, Crum CP, Munger K. 2000. The human papillomavirus type 16 E6 and E7 oncoproteins cooperate to induce mitotic defects and genomic instability by uncoupling centrosome duplication from the cell division cycle. Proc Natl Acad Sci USA 97:10002-10007. (Pubitemid 30680845)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.18
, pp. 10002-10007
-
-
Duensing, S.1
Lee, L.Y.2
Duensing, A.3
Basile, J.4
Piboonniyom, S.-O.5
Gonzalez, S.6
Crum, C.P.7
Munger, K.8
-
17
-
-
1242281345
-
Excessive centrosome abnormalities without ongoing numerical chromosome instability in a Burkitt's lymphoma
-
DOI 10.1186/1476-4598-2-30
-
Duensing S, Lee BH, Dal Cin P, Munger K. 2003. Excessive centrosome abnormalities without ongoing numerical chromosome instability in a Burkitt's lymphoma. Mol Cancer 2:30. (Pubitemid 38751467)
-
(2003)
Molecular Cancer
, vol.2
, pp. 30
-
-
Duensing, S.1
Lee, B.H.2
Dal Cin, P.3
Munger, K.4
-
18
-
-
39749106551
-
Aurora a kinase RNAi and small molecule inhibition of Aurora kinases with VE-465 induce apoptotic death in multiple myeloma cells
-
DOI 10.1080/10428190701824544, PII 790279671
-
Evans R, Naber C, Steffler T, Checkland T, Keats J, Maxwell C, Perry T, Chau H, Belch A, Pilarski L, Reiman T. 2008a. Aurora A kinase RNAi and small molecule inhibition of Aurora kinases with VE-465 induce apoptotic death in multiple myeloma cells. Leuk Lymphoma 49:559-569. (Pubitemid 351298342)
-
(2008)
Leukemia and Lymphoma
, vol.49
, Issue.3
, pp. 559-569
-
-
Evans, R.1
Naber, C.2
Steffler, T.3
Checkland, T.4
Keats, J.5
Maxwell, C.6
Perry, T.7
Chau, H.8
Belch, A.9
Pilarski, L.10
Reiman, T.11
-
19
-
-
38349108184
-
The selective Aurora B kinase inhibitor AZD1152 is a potential new treatment for multiple myeloma
-
Evans RP, Naber C, Steffler T, Checkland T, Maxwell CA, Keats JJ, Belch AR, Pilarski LM, Lai R, Reiman T. 2008b. The selective Aurora B kinase inhibitor AZD1152 is a potential new treatment for multiple myeloma. Br J Haematol 140:295-302.
-
(2008)
Br J Haematol
, vol.140
, pp. 295-302
-
-
Evans, R.P.1
Naber, C.2
Steffler, T.3
Checkland, T.4
Maxwell, C.A.5
Keats, J.J.6
Belch, A.R.7
Pilarski, L.M.8
Lai, R.9
Reiman, T.10
-
20
-
-
0037103287
-
Genomic abnormalities in monoclonal gammopathy of undetermined significance
-
Fonseca R, Bailey RJ, Ahmann GJ, Rajkumar SV, Hoyer JD, Lust JA, Kyle RA, Gertz MA, Greipp PR, Dewald GW. 2002. Genomic abnormalities in monoclonal gammopathy of undetermined significance. Blood 100:1417-1424. (Pubitemid 34864300)
-
(2002)
Blood
, vol.100
, Issue.4
, pp. 1417-1424
-
-
Fonseca, R.1
Bailey, R.J.2
Ahmann, G.J.3
Vincent Rajkumar, S.4
Hoyer, J.D.5
Lust, J.A.6
Kyle, R.A.7
Gertz, M.A.8
Greipp, P.R.9
Dewald, G.W.10
-
21
-
-
0141481984
-
The recurrent IgH translocations are highly associated with nonhyperdiploid variant multiple myeloma
-
DOI 10.1182/blood-2003-02-0493
-
Fonseca R, Debes-Marun CS, Picken EB, Dewald GW, Bryant SC, Winkler JM, Blood E, Oken MM, Santana-Davila R, Gonzalez-Paz N, Kyle RA, Gertz MA, Dispenzieri A, Lacy MQ, Greipp PR. 2003. The recurrent IgH translocations are highly associated with nonhyperdiploid variant multiple myeloma. Blood 102:2562-2567. (Pubitemid 37193596)
-
(2003)
Blood
, vol.102
, Issue.7
, pp. 2562-2567
-
-
Fonseca, R.1
Debes-Marun, C.S.2
Picken, E.B.3
Dewald, G.W.4
Bryant, S.C.5
Winkler, J.M.6
Blood, E.7
Oken, M.M.8
Santana-Davila, R.9
Gonzalez-Paz, N.10
Kyle, R.A.11
Gertz, M.A.12
Dispenzieri, A.13
Lacy, M.Q.14
Greipp, P.R.15
-
22
-
-
10744223381
-
Genetics and Cytogenetics of Multiple Myeloma: A Workshop Report
-
DOI 10.1158/0008-5472.CAN-03-2876
-
Fonseca R, Barlogie B, Bataille R, Bastard C, Bergsagel PL, Chesi M, Davies FE, Drach J, Greipp PR, Kirsch IR, Kuehl WM, Hernandez JM, Minvielle S, Pilarski LM, Shaughnessy JD Jr, Stewart AK, Avet-Loiseau H. 2004. Genetics and cytogenetics of multiple myeloma: A workshop report. Cancer Res 64:1546-1558. (Pubitemid 38235629)
-
(2004)
Cancer Research
, vol.64
, Issue.4
, pp. 1546-1558
-
-
Fonseca, R.1
Barlogie, B.2
Bataille, R.3
Bastard, C.4
Bergsagel, P.L.5
Chesi, M.6
Davies, F.E.7
Drach, J.8
Greipp, P.R.9
Kirsch, I.R.10
Kuehl, W.M.11
Hernandez, J.M.12
Minvielle, S.13
Pilarski, L.M.14
Shaughnessy Jr., J.D.15
Stewart, A.K.16
Avet-Loiseau, H.17
-
23
-
-
36448987217
-
Oncogenes and tumour suppressors take on centrosomes
-
DOI 10.1038/nrc2249, PII NRC2249
-
Fukasawa K. 2007. Oncogenes and tumour suppressors take on centrosomes. Nat Rev Cancer 7:911-924. (Pubitemid 350165854)
-
(2007)
Nature Reviews Cancer
, vol.7
, Issue.12
, pp. 911-924
-
-
Fukasawa, K.1
-
24
-
-
33748047128
-
RB and cell cycle progression
-
Giacinti C, Giordano A. 2006. RB and cell cycle progression. Oncogene 25:5220-5227.
-
(2006)
Oncogene
, vol.25
, pp. 5220-5227
-
-
Giacinti, C.1
Giordano, A.2
-
25
-
-
21744458439
-
Centrosome aberrations in chronic myeloid leukemia correlate with stage of disease and chromosomal instability
-
DOI 10.1038/sj.leu.2403779
-
Giehl M, Fabarius A, Frank O, Hochhaus A, Hafner M, Hehlmann R, Seifarth W. 2005. Centrosome aberrations in chronic myeloid leukemia correlate with stage of disease and chromosomal instability. Leukemia 19:1192-1197. (Pubitemid 40946003)
-
(2005)
Leukemia
, vol.19
, Issue.7
, pp. 1192-1197
-
-
Giehl, M.1
Fabarius, A.2
Frank, O.3
Hochhaus, A.4
Hafner, M.5
Hehlmann, R.6
Seifarth, W.7
-
26
-
-
33846852215
-
Tumor suppressor p16 methylation in multiple myeloma: Biological and clinical implications
-
DOI 10.1182/blood-2006-05-024661
-
Gonzalez-Paz N, Chng WJ, McClure RF, Blood E, Oken MM, Van Ness B, James CD, Kurtin PJ, Henderson K, Ahmann GJ, Gertz M, Lacy M, Dispenzieri A, Greipp PR, Fonseca R. 2007. Tumor suppressor p16 methylation in multiple myeloma: Biological and clinical implications. Blood 109:1228-1232. (Pubitemid 46220672)
-
(2007)
Blood
, vol.109
, Issue.3
, pp. 1228-1232
-
-
Gonzalez-Paz, N.1
Chng, W.J.2
McClure, R.F.3
Blood, E.4
Oken, M.M.5
Van Ness, B.6
James, C.D.7
Kurtin, P.J.8
Henderson, K.9
Ahmann, G.J.10
Gertz, M.11
Lacy, M.12
Dispenzieri, A.13
Greipp, P.R.14
Fonseca, R.15
-
27
-
-
0033766813
-
Centrosome hyperamplification in head and neck squamous cell carcinoma: A potential phenotypic marker of tumor aggressiveness
-
Gustafson LM, Gleich LL, Fukasawa K, Chadwell J, Miller MA, Stambrook PJ, Gluckman JL. 2000. Centrosome hyperamplification in head and neck squamous cell carcinoma: A potential phenotypic marker of tumor aggressiveness. Laryngoscope 110:1798-1801. (Pubitemid 30833095)
-
(2000)
Laryngoscope
, vol.110
, Issue.11
, pp. 1798-1801
-
-
Gustafson, L.M.1
Gleich, L.L.2
Fukasawa, K.3
Chadwell, J.4
Miller, M.A.5
Stambrook, P.J.6
Gluckman, J.L.7
-
28
-
-
0029070913
-
Overexpression of the hyaluronan receptor RHAMM is transforming and is also required for H-ras transformation
-
Hall CL, Yang B, Yang X, Zhang S, Turley M, Samuel S, Lange LA, Wang C, Curpen GD, Savani RC, Greenberg AH, Turley EA. 1995. Overexpression of the hyaluronan receptor RHAMM is transforming and is also required for H-ras transformation. Cell 82:19-26.
-
(1995)
Cell
, vol.82
, pp. 19-26
-
-
Hall, C.L.1
Yang, B.2
Yang, X.3
Zhang, S.4
Turley, M.5
Samuel, S.6
Lange, L.A.7
Wang, C.8
Curpen, G.D.9
Savani, R.C.10
Greenberg, A.H.11
Turley, E.A.12
-
29
-
-
1442285889
-
Overexpression of c-maf is a frequent oncogenic event in multiple myeloma that promotes proliferation and pathological interactions with bone marrow stroma
-
DOI 10.1016/S1535-6108(04)00019-4, PII S1535610804000194
-
Hurt EM, Wiestner A, Rosenwald A, Shaffer AL, Campo E, Grogan T, Bergsagel PL, Kuehl WM, Staudt LM. 2004. Overexpression of c-maf is a frequent oncogenic event in multiple myeloma that promotes proliferation and pathological interactions with bone marrow stroma. Cancer Cell 5:191-199. (Pubitemid 38283804)
-
(2004)
Cancer Cell
, vol.5
, Issue.2
, pp. 191-199
-
-
Hurt, E.M.1
Wiestner, A.2
Rosenwald, A.3
Shaffer, A.L.4
Campo, E.5
Grogan, T.6
Bergsagel, P.L.7
Kuehl, W.M.8
Staudt, L.M.9
-
30
-
-
33750220492
-
RB acute loss induces centrosome amplification and aneuploidy in murine primary fibroblasts
-
DOI 10.1186/1476-4598-5-38
-
Iovino F, Lentini L, Amato A, Di Leonardo A. 2006. RB acute loss induces centrosome amplification and aneuploidy in murine primary fibroblasts. Mol Cancer 5:38. (Pubitemid 44604825)
-
(2006)
Molecular Cancer
, vol.5
, pp. 38
-
-
Iovino, F.1
Lentini, L.2
Amato, A.3
Di Leonardo, A.4
-
31
-
-
33846457870
-
Cancer statistics, 2007
-
Jemal A, Siegel R, Ward E, Murray T, Xu J, Thun MJ. 2007. Cancer statistics, 2007. CA Cancer J Clin 57:43-66.
-
(2007)
CA Cancer J Clin
, vol.57
, pp. 43-66
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
Murray, T.4
Xu, J.5
Thun, M.J.6
-
32
-
-
33750434275
-
The BRCA1/BARD1 Heterodimer Modulates Ran-Dependent Mitotic Spindle Assembly
-
DOI 10.1016/j.cell.2006.08.053, PII S0092867406012815
-
Joukov V, Groen AC, Prokhorova T, Gerson R, White E, Rodriguez A, Walter JC, Livingston DM. 2006. The BRCA1/BARD1 heterodimer modulates ran-dependent mitotic spindle assembly. Cell 127:539-552. (Pubitemid 44647427)
-
(2006)
Cell
, vol.127
, Issue.3
, pp. 539-552
-
-
Joukov, V.1
Groen, A.C.2
Prokhorova, T.3
Gerson, R.4
White, E.5
Rodriguez, A.6
Walter, J.C.7
Livingston, D.M.8
-
33
-
-
9144251019
-
Phosphorylation by aurora kinase a induces Mdm2-mediated destabilization and inhibition of p53
-
DOI 10.1038/ng1279
-
Katayama H, Sasai K, Kawai H, Yuan ZM, Bondaruk J, Suzuki F, Fujii S, Arlinghaus RB, Czerniak BA, Sen S. 2004. Phosphorylation by aurora kinase A induces Mdm2-mediated destabilization and inhibition of p53. Nat Genet 36:55-62. (Pubitemid 38056208)
-
(2004)
Nature Genetics
, vol.36
, Issue.1
, pp. 55-62
-
-
Katayama, H.1
Sasai, K.2
Kawai, H.3
Yuan, Z.-M.4
Bondaruk, J.5
Suzuki, F.6
Fujii, S.7
Arlinghaus, R.B.8
Czerniak, B.A.9
Sen, S.10
-
34
-
-
10744221244
-
Centrosome aberrations as a possible mechanism for chromosomal instability in non-Hodgkin's lymphoma
-
DOI 10.1038/sj.leu.2403142
-
Kramer A, Schweizer S, Neben K, Giesecke C, Kalla J, Katzenberger T, Benner A, Muller-Hermelink HK, Ho AD, Ott G. 2003. Centrosome aberrations as a possible mechanism for chromosomal instability in non-Hodgkin's lymphoma. Leukemia 17:2207-2213. (Pubitemid 37428388)
-
(2003)
Leukemia
, vol.17
, Issue.11
, pp. 2207-2213
-
-
Kramer, A.1
Schweizer, S.2
Neben, K.3
Giesecke, C.4
Kalla, J.5
Katzenberger, T.6
Benner, A.7
Muller-Hermelink, H.K.8
Ho, A.D.9
Ott, G.10
-
35
-
-
0036512435
-
Multiple myeloma: Evolving genetic events and host interactions
-
Kuehl WM, Bergsagel PL. 2002. Multiple myeloma: Evolving genetic events and host interactions. Nat Rev Cancer 2:175-187.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 175-187
-
-
Kuehl, W.M.1
Bergsagel, P.L.2
-
36
-
-
0037135979
-
Human TPX2 is required for targeting Aurora-A kinase to the spindle
-
DOI 10.1083/jcb.200204155
-
Kufer TA, Sillje HH, Korner R, Gruss OJ, Meraldi P, Nigg EA. 2002. Human TPX2 is required for targeting Aurora-A kinase to the spindle. J Cell Biol 158:617-623. (Pubitemid 34920101)
-
(2002)
Journal of Cell Biology
, vol.158
, Issue.4
, pp. 617-623
-
-
Kufer, T.A.1
Sillje, H.H.W.2
Korner, R.3
Gruss, O.J.4
Meraldi, P.5
Nigg, E.A.6
-
37
-
-
41949130070
-
Improved survival in multiple myeloma and the impact of novel therapies
-
Kumar SK, Rajkumar SV, Dispenzieri A, Lacy MQ, Hayman SR, Buadi FK, Zeldenrust SR, Dingli D, Russell SJ, Lust JA, Greipp PR, Kyle RA, Gertz MA. 2008. Improved survival in multiple myeloma and the impact of novel therapies. Blood 111:2516-2520.
-
(2008)
Blood
, vol.111
, pp. 2516-2520
-
-
Kumar, S.K.1
Rajkumar, S.V.2
Dispenzieri, A.3
Lacy, M.Q.4
Hayman, S.R.5
Buadi, F.K.6
Zeldenrust, S.R.7
Dingli, D.8
Russell, S.J.9
Lust, J.A.10
Greipp, P.R.11
Kyle, R.A.12
Gertz, M.A.13
-
38
-
-
0033976952
-
Centrosome abnormalities in human carcinomas of the gallbladder and intrahepatic and extrahepatic bile ducts
-
Kuo KK, Sato N, Mizumoto K, Maehara N, Yonemasu H, Ker CG, Sheen PC, Tanaka M. 2000. Centrosome abnormalities in human carcinomas of the gallbladder and intrahepatic and extrahepatic bile ducts. Hepatology 31:59-64. (Pubitemid 30033690)
-
(2000)
Hepatology
, vol.31
, Issue.1
, pp. 59-64
-
-
Kuo, K.-K.1
Sato, N.2
Mizumoto, K.3
Maehara, N.4
Yonemasu, H.5
Ker, C.-G.6
Sheen, P.-C.7
Tanaka, M.8
-
39
-
-
42449114035
-
Multiple myeloma
-
Kyle RA, Rajkumar SV. 2008. Multiple myeloma. Blood 111:2962-2972.
-
(2008)
Blood
, vol.111
, pp. 2962-2972
-
-
Kyle, R.A.1
Rajkumar, S.V.2
-
41
-
-
0032805944
-
Altered centrosome structure is associated with abnormal mitoses in human breast tumors
-
Lingle WL, Salisbury JL. 1995. Altered centrosome structure is associated with abnormal mitoses in human breast tumors. Am J Pathol 155:1941-1951.
-
(1995)
Am J Pathol
, vol.155
, pp. 1941-1951
-
-
Lingle, W.L.1
Salisbury, J.L.2
-
42
-
-
0032539868
-
Centrosome hypertrophy in human breast tumors: Implications for genomic stability and cell polarity
-
Lingle WL, Lutz WH, Ingle JN, Maihle NJ, Salisbury JL. 1998. Centrosome hypertrophy in human breast tumors: Implications for genomic stability and cell polarity. Proc Natl Acad Sci USA 95:2950-2955.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 2950-2955
-
-
Lingle, W.L.1
Lutz, W.H.2
Ingle, J.N.3
Maihle, N.J.4
Salisbury, J.L.5
-
43
-
-
0037133211
-
Centrosome amplification drives chromosomal instability in breast tumor development
-
DOI 10.1073/pnas.032479999
-
Lingle WL, Barrett SL, Negron VC, D'Assoro AB, Boeneman K, Liu W, Whitehead CM, Reynolds C, Salisbury JL. 2002. Centrosome amplification drives chromosomal instability in breast tumor development. Proc Natl Acad Sci USA 99:1978-1983. (Pubitemid 34169000)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.4
, pp. 1978-1983
-
-
Lingle, W.L.1
Barrett, S.L.2
Negron, V.C.3
D'Assoro, A.B.4
Boeneman, K.5
Liu, W.6
Whitehead, C.M.7
Reynolds, C.8
Salisbury, J.L.9
-
44
-
-
0025991565
-
Formation of the tetraploid intermediate is associated with the development of cells with more than four centrioles in the elastase-simian virus 40 tumor antigen transgenic mouse model of pancreatic cancer
-
Levine DS, Sanchez CA, Rabinovitch PS, Reid BJ. 1991. Formation of the tetraploid intermediate is associated with the development of cells with more than four centrioles in the elastase-simian virus 40 tumor antigen transgenic mouse model of pancreatic cancer. Proc Natl Acad Sci USA 88:6427-6431.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 6427-6431
-
-
Levine, D.S.1
Sanchez, C.A.2
Rabinovitch, P.S.3
Reid, B.J.4
-
45
-
-
27244432264
-
A potential role for centrosomal deregulation within IgH translocation-positive myeloma
-
Maxwell CA, Pilarski LM. 2005. A potential role for centrosomal deregulation within IgH translocation-positive myeloma. Med Hypotheses 65:915-921.
-
(2005)
Med Hypotheses
, vol.65
, pp. 915-921
-
-
Maxwell, C.A.1
Pilarski, L.M.2
-
46
-
-
0037632929
-
RHAMM is a centrosomal protein that interacts with dynein and maintains spindle pole stability
-
DOI 10.1091/mbc.E02-07-0377
-
Maxwell CA, Keats JJ, Crainie M, Sun X, Yen T, Shibuya E, Hendzel M, Chan G, Pilarski LM. 2003. RHAMM is a centrosomal protein that interacts with dynein and maintains spindle pole stability. Mol Biol Cell 14:2262-2276. (Pubitemid 36724319)
-
(2003)
Molecular Biology of the Cell
, vol.14
, Issue.6
, pp. 2262-2276
-
-
Maxwell, C.A.1
Keats, J.J.2
Crainie, M.3
Sun, X.4
Yen, T.5
Shibuya, E.6
Hendzel, M.7
Chan, G.8
Pilarski, L.M.9
-
47
-
-
3843096002
-
RHAMM expression and isoform balance predict aggressive disease and poor survival in multiple myeloma
-
DOI 10.1182/blood-2003-11-4079
-
Maxwell CA, Rasmussen E, Zhan F, Keats JJ, Adamia S, Strachan E, Crainie M, Walker R, Belch AR, Pilarski LM, Barlogie B, Shaughnessy J Jr, Reiman T. 2004. RHAMM expression and isoform balance predict aggressive disease and poor survival in multiple myeloma. Blood 104:1151-1158. (Pubitemid 39038037)
-
(2004)
Blood
, vol.104
, Issue.4
, pp. 1151-1158
-
-
Maxwell, C.A.1
Rasmussen, E.2
Zhan, F.3
Keats, J.J.4
Adamia, S.5
Strachan, E.6
Crainie, M.7
Walker, R.8
Belch, A.R.9
Pilarski, L.M.10
Barlogie, B.11
Shaughnessy Jr., J.12
Reiman, T.13
-
48
-
-
13444294239
-
Receptor for hyaluronan-mediated motility correlates with centrosome abnormalities in multiple myeloma and maintains mitotic integrity
-
Maxwell CA, Keats JJ, Belch AR, Pilarski LM, Reiman T. 2005. Receptor for hyaluronan-mediated motility correlates with centrosome abnormalities in multiple myeloma and maintains mitotic integrity. Cancer Res 65:850-860. (Pubitemid 40216444)
-
(2005)
Cancer Research
, vol.65
, Issue.3
, pp. 850-860
-
-
Maxwell, C.A.1
Keats, J.J.2
Belch, A.R.3
Pilarski, L.M.4
Reiman, T.5
-
49
-
-
0034704780
-
Synergistic induction of centrosome hyperamplification by loss of p53 and cyclin e overexpression
-
Mussman JG, Horn HF, Carroll PE, Okuda M, Tarapore P, Donehower LA, Fukasawa K. 2000. Synergistic induction of centrosome hyperamplification by loss of p53 and cyclin E overexpression. Oncogene 19:1635-1646. (Pubitemid 30200965)
-
(2000)
Oncogene
, vol.19
, Issue.13
, pp. 1635-1646
-
-
Mussman, J.G.1
Horn, H.F.2
Carroll, P.E.3
Okuda, M.4
Tarapore, P.5
Donehower, L.A.6
Fukasawa, K.7
-
50
-
-
0037218006
-
Centrosome aberrations in acute myeloid leukemia are correlated with cytogenetic risk profile
-
DOI 10.1182/blood-2002-04-1188
-
Neben K, Giesecke C, Schweizer S, Ho AD, Kramer A. 2003. Centrosome aberrations in acute myeloid leukemia are correlated with cytogenetic risk profile. Blood 101:289-291. (Pubitemid 36025920)
-
(2003)
Blood
, vol.101
, Issue.1
, pp. 289-291
-
-
Neben, K.1
Glesecke, C.2
Schweizer, S.3
Ho, A.D.4
Kramer, A.5
-
51
-
-
11144354652
-
Gene expression patterns in acute myeloid leukemia correlate with centrosome aberrations and numerical chromosome changes
-
DOI 10.1038/sj.onc.1207401
-
Neben K, Tews B, Wrobel G, Hahn M, Kokocinski F, Giesecke C, Krause U, Ho AD, Kramer A, Lichter P. 2004. Gene expression patterns in acute myeloid leukemia correlate with centrosome aberrations and numerical chromosome changes. Oncogene 23:2379-2384. (Pubitemid 38496793)
-
(2004)
Oncogene
, vol.23
, Issue.13
, pp. 2379-2384
-
-
Neben, K.1
Tews, B.2
Wrobel, G.3
Hahn, M.4
Kokocinski, F.5
Giesecke, C.6
Krause, U.7
Ho, A.D.8
Kramer, A.9
Lichter, P.10
-
52
-
-
12844288920
-
Short term cyclin D1 overexpression induces centrosome amplification, mitotic spindle abnormalities, and aneuploidy
-
DOI 10.1074/jbc.M407105200
-
Nelsen CJ, Kuriyama R, Hirsch B, Negron VC, Lingle WL, Goggin MM, Stanley MW, Albrecht JH. 2005. Short term cyclin D1 overexpression induces centrosome amplification, mitotic spindle abnormalities, and aneuploidy. J Biol Chem 280:768-776. (Pubitemid 40165045)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.1
, pp. 768-776
-
-
Nelsen, C.J.1
Kuriyama, R.2
Hirsch, B.3
Negron, V.C.4
Lingle, W.L.5
Goggin, M.M.6
Stanley, M.W.7
Albrecht, J.H.8
-
53
-
-
0036831681
-
Centrosome aberrations: Cause or consequence of cancer progression?
-
Nigg EA. 2002. Centrosome aberrations: Cause or consequence of cancer progression? Nat Rev Cancer 2:815-825.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 815-825
-
-
Nigg, E.A.1
-
54
-
-
2442584567
-
2 to M Transition
-
DOI 10.1074/jbc.M311780200
-
Ouchi M, Fujiuchi N, Sasai K, Katayama H, Minamishima YA, Ongusaha PP, Deng C, Sen S, Lee SW, Ouchi T. 2004. BRCA1 phosphorylation by Aurora-A in the regulation of G2 to M transition. J Biol Chem 279:19643-19648. (Pubitemid 38623401)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.19
, pp. 19643-19648
-
-
Ouchi, M.1
Fujiuchi, N.2
Sasai, K.3
Katayama, H.4
Minamishima, Y.A.5
Ongusaha, P.P.6
Deng, C.7
Sen, S.8
Lee, S.W.9
Ouchi, T.10
-
55
-
-
0041883657
-
Mutations and aneuploidy: Co-conspirators in cancer?
-
Pihan G, Doxsey SJ. 2003. Mutations and aneuploidy: Co-conspirators in cancer? Cancer Cell 4:89-94.
-
(2003)
Cancer Cell
, vol.4
, pp. 89-94
-
-
Pihan, G.1
Doxsey, S.J.2
-
56
-
-
0032170033
-
Centrosome defects and genetic instability in malignant tumors
-
Pihan GA, Purohit A, Wallace J, Knecht H, Woda B, Quesenberry P, Doxsey SJ. 1998. Centrosome defects and genetic instability in malignant tumors. Cancer Res 58:3974-3985. (Pubitemid 28405657)
-
(1998)
Cancer Research
, vol.58
, Issue.17
, pp. 3974-3985
-
-
Pihan, G.A.1
Purohit, A.2
Wallace, J.3
Knecht, H.4
Woda, B.5
Quesenberry, P.6
Doxsey, S.J.7
-
57
-
-
0035266301
-
Centrosome defects can account for cellular and genetic changes that characterize prostate cancer progression
-
Pihan GA, Purohit A, Wallace J, Malhotra R, Liotta L, Doxsey SJ. 2001. Centrosome defects can account for cellular and genetic changes that characterize prostate cancer progression. Cancer Res 61:2212-2219. (Pubitemid 32692050)
-
(2001)
Cancer Research
, vol.61
, Issue.5
, pp. 2212-2219
-
-
Pihan, G.A.1
Purohit, A.2
Wallace, J.3
Malhotra, R.4
Liotta, L.5
Doxsey, S.J.6
-
58
-
-
0037444168
-
Centrosome abnormalities and chromosome instability occur together in pre-invasive carcinomas
-
Pihan GA, Wallace J, Zhou Y, Doxsey SJ. 2003. Centrosome abnormalities and chromosome instability occur together in pre-invasive carcinomas. Cancer Res 63:1398-1404. (Pubitemid 36348723)
-
(2003)
Cancer Research
, vol.63
, Issue.6
, pp. 1398-1404
-
-
Pihan, G.A.1
Wallace, J.2
Zhou, Y.3
Doxsey, S.J.4
-
59
-
-
11844289563
-
Spindle multipolarity is prevented by centrosomal clustering
-
DOI 10.1126/science.1104905
-
Quintyne NJ, Reing JE, Hoffelder DR, Gollin SM, Saunders WS. 2005. Spindle multipolarity is prevented by centrosomal clustering. Science 307:127-129. (Pubitemid 40093495)
-
(2005)
Science
, vol.307
, Issue.5706
, pp. 127-129
-
-
Quintyne, N.J.1
Reing, J.E.2
Hoffelder, D.R.3
Gollin, S.M.4
Saunders, W.S.5
-
60
-
-
0036569124
-
Centrosomes and cancer: Lessons from a TACC
-
Raff JW. 2002. Centrosomes and cancer: Lessons from a TACC. Trends Cell Biol 12:222-225.
-
(2002)
Trends Cell Biol
, vol.12
, pp. 222-225
-
-
Raff, J.W.1
-
61
-
-
38349116712
-
Aurora kinases as therapeutic targets in multiple myeloma
-
Abstract 847
-
Reiman T, Evans RP, Naber CTS, Keats JJ, Perry T, Maxwell CA, Chau H, Belch A, Pilarski L. 2006. Aurora kinases as therapeutic targets in multiple myeloma. Blood 108:[Abstract 847].
-
(2006)
Blood
, vol.108
-
-
Reiman, T.1
Evans, R.P.2
Naber, C.T.S.3
Keats, J.J.4
Perry, T.5
Maxwell, C.A.6
Chau, H.7
Belch, A.8
Pilarski, L.9
-
62
-
-
33751168729
-
Centrosome function in normal and tumor cells
-
DOI 10.1002/jcb.21003
-
Sankaran S, Parvin JD. 2006. Centrosome function in normal and tumor cells. J Cell Biochem 99:1240-1250. (Pubitemid 44778458)
-
(2006)
Journal of Cellular Biochemistry
, vol.99
, Issue.5
, pp. 1240-1250
-
-
Sankaran, S.1
Parvin, J.D.2
-
63
-
-
0032931205
-
Centrosome abnormalities in pancreatic ductal carcinoma
-
Sato N, Mizumoto K, Nakamura M, Nakamura K, Kusumoto M, Niiyama H, Ogawa T, Tanaka M. 1999. Centrosome abnormalities in pancreatic ductal carcinoma. Clin Cancer Res 5:963-970. (Pubitemid 29233208)
-
(1999)
Clinical Cancer Research
, vol.5
, Issue.5
, pp. 963-970
-
-
Sato, N.1
Mizumoto, K.2
Nakamura, M.3
Nakamura, K.4
Kusumoto, M.5
Niiyama, H.6
Ogawa, T.7
Tanaka, M.8
-
64
-
-
34247393658
-
Targeting aurora kinases as therapy in multiple myeloma
-
DOI 10.1182/blood-2006-07-037671
-
Shi Y, Reiman T, Li W, Maxwell CA, Sen S, Pilarski L, Daniels TR, Penichet ML, Feldman R, Lichtenstein A. 2007. Targeting aurora kinases as therapy in multiple myeloma. Blood 109:3915-3921. (Pubitemid 46641744)
-
(2007)
Blood
, vol.109
, Issue.9
, pp. 3915-3921
-
-
Shi, Y.1
Reiman, T.2
Li, W.3
Maxwell, C.A.4
Sen, S.5
Pilarski, L.6
Daniels, T.R.7
Penichet, M.L.8
Feldman, R.9
Lichtenstein, A.10
-
65
-
-
0037341906
-
A Ran signalling pathway mediated by the mitotic kinase Aurora a in spindle assembly
-
DOI 10.1038/ncb936
-
Tsai MY, Wiese C, Cao K, Martin O, Donovan P, Ruderman J, Prigent C, Zheng Y. 2003. A Ran signalling pathway mediated by the mitotic kinase Aurora A in spindle assembly. Nat Cell Biol 5:242-248. (Pubitemid 36322252)
-
(2003)
Nature Cell Biology
, vol.5
, Issue.3
, pp. 242-248
-
-
Tsai, M.-Y.1
Wiese, C.2
Cao, K.3
Martin, O.4
Donovan, P.5
Ruderman, J.6
Prigent, C.7
Zheng, Y.8
-
66
-
-
0030250252
-
Chromosome aberrations, micronuclei, aneuploidy, sister chromatid exchanges, and cancer risk assessment
-
Tucker JD, Preston RJ. 1996. Chromosome aberrations, micronuclei, aneuploidy, sister chromatid exchanges, and cancer risk assessment. Mutat Res 365:147-159.
-
(1996)
Mutat Res
, vol.365
, pp. 147-159
-
-
Tucker, J.D.1
Preston, R.J.2
-
68
-
-
2942679807
-
Cell cycle progression after cleavage failure: Mammalian somatic cells do not possess a "tetraploidy checkpoint."
-
Uetake Y, Sluder G. 2004. Cell cycle progression after cleavage failure: Mammalian somatic cells do not possess a "tetraploidy checkpoint." J Cell Biol 165:609-615.
-
(2004)
J Cell Biol
, vol.165
, pp. 609-615
-
-
Uetake, Y.1
Sluder, G.2
-
69
-
-
6344235546
-
1/S transition
-
DOI 10.1074/jbc.M406240200
-
Ussar S, Voss T. 2004. MEK1 and MEK2, different regulators of the G1/S transition. J Biol Chem 279:43861-43869. (Pubitemid 39390693)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.42
, pp. 43861-43869
-
-
Ussar, S.1
Voss, T.2
-
70
-
-
0036730664
-
The oncogenic potential of Kaposi's sarcoma-associated herpesvirus cyclin is exposed by p53 loss in vitro and in vivo
-
DOI 10.1016/S1535-6108(02)00123-X
-
Verschuren EW, Klefstrom J, Evan GI, Jones N. 2002. The oncogenic potential of Kaposi's sarcoma-associated herpesvirus cyclin is exposed by p53 loss in vitro and in vivo. Cancer Cell 2:229-241. (Pubitemid 41043978)
-
(2002)
Cancer Cell
, vol.2
, Issue.3
, pp. 229-241
-
-
Verschuren, E.W.1
Klefstrom, J.2
Evan, G.I.3
Jones, N.4
-
71
-
-
0038235696
-
Telomerase and telomere length in multiple myeloma: Correlations with disease heterogeneity, cytogenetic status, and overall survival
-
Wu K-D, Orme LM, Shaughnessy J Jr, Jacobson J, Barlogie B, Moore MAS. 2003. Telomerase and telomere length in multiple myeloma: Correlations with disease heterogeneity, cytogenetic status, and overall survival. Blood 101:4982-4989. (Pubitemid 36868943)
-
(2003)
Blood
, vol.101
, Issue.12
, pp. 4982-4989
-
-
Wu, K.-D.1
Orme, L.M.2
Shaughnessy Jr., J.3
Jacobson, J.4
Barlogie, B.5
Moore, M.A.S.6
-
72
-
-
0027513932
-
Identification of two hyaluronan-binding domains in the hyaluronan receptor RHAMM
-
Yang B, Zhang L, Turley EA. 1993. Identification of two hyaluronan-binding domains in the hyaluronan receptor RHAMM. J Biol Chem 268:8617-8623. (Pubitemid 23118644)
-
(1993)
Journal of Biological Chemistry
, vol.268
, Issue.12
, pp. 8617-8623
-
-
Yang, B.1
Zhang, L.2
Turley, E.A.3
-
73
-
-
33745779502
-
The molecular classification of multiple myeloma
-
Zhan F, Huang Y, Colla S, Stewart JP, Hanamura I, Gupta S, Epstein J, Yaccoby S, Sawyer J, Burington B, Anaissie E, Hollmig K, Pineda-Roman M, Tricot G, van Rhee F, Walker R, Zangari M, Crowley J, Barlogie B, Shaughnessy JD Jr. 2006. The molecular classification of multiple myeloma. Blood 108:2020-2028.
-
(2006)
Blood
, vol.108
, pp. 2020-2028
-
-
Zhan, F.1
Huang, Y.2
Colla, S.3
Stewart, J.P.4
Hanamura, I.5
Gupta, S.6
Epstein, J.7
Yaccoby, S.8
Sawyer, J.9
Burington, B.10
Anaissie, E.11
Hollmig, K.12
Pineda-Roman, M.13
Tricot, G.14
Van Rhee, F.15
Walker, R.16
Zangari, M.17
Crowley, J.18
Barlogie, B.19
Shaughnessy Jr., J.D.20
more..
-
74
-
-
0032080068
-
The hyaluronan receptor RHAMM regulates extracellular-regulated kinase
-
DOI 10.1074/jbc.273.18.11342
-
Zhang S, Chang MC, Zylka D, Turley S, Harrison R, Turley EA. 1998. The hyaluronan receptor RHAMM regulates extracellular-regulated kinase. J Biol Chem 273:11342-11348. (Pubitemid 28204989)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.18
, pp. 11342-11348
-
-
Zhang, S.1
Chang, M.C.Y.2
Zylka, D.3
Turley, S.4
Harrison, R.5
Turley, E.A.6
-
75
-
-
0031714080
-
Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation
-
DOI 10.1038/2496
-
Zhou H, Kuang J, Zhong L, Kuo WL, Gray JW, Sahin A, Brinkley BR, Sen S. 1998. Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation. Nat Genet 20:189-193. (Pubitemid 28455454)
-
(1998)
Nature Genetics
, vol.20
, Issue.2
, pp. 189-193
-
-
Zhou, H.1
Kuang, J.2
Zhong, L.3
Kuo, W.-L.4
Gray, J.W.5
Sahin, A.6
Brinkley, B.R.7
Sen, S.8
|