-
1
-
-
0036468420
-
Centrosome composition and microtubule anchoring mechanisms
-
Bornens M. Centrosome composition and microtubule anchoring mechanisms. Curr Opin Cell Biol. 2002;14:25-34.
-
(2002)
Curr Opin Cell Biol
, vol.14
, pp. 25-34
-
-
Bornens, M.1
-
2
-
-
0033766813
-
Centrosome hyperamplification in head and neck squamous cell carcinoma: A potential phenotypic marker of tumor aggressiveness
-
Gustafson LM, Gleich LL, Fukasawa K, et al. Centrosome hyperamplification in head and neck squamous cell carcinoma: a potential phenotypic marker of tumor aggressiveness. Laryngoscope. 2000;110:1798-1801.
-
(2000)
Laryngoscope
, vol.110
, pp. 1798-1801
-
-
Gustafson, L.M.1
Gleich, L.L.2
Fukasawa, K.3
-
3
-
-
0033976952
-
Centrosome abnormalities in human carcinomas of the gall-bladder and intrahepatic and extrahepatic bile ducts
-
Kuo KK, Sato N, Mizumoto K, et al. Centrosome abnormalities in human carcinomas of the gall-bladder and intrahepatic and extrahepatic bile ducts. Hepatology. 2000;31:59-64.
-
(2000)
Hepatology
, vol.31
, pp. 59-64
-
-
Kuo, K.K.1
Sato, N.2
Mizumoto, K.3
-
4
-
-
0032539868
-
Centrosome hypertrophy in human breast tumors: Implications for genomic stability and cell polarity
-
Lingle WL, Lutz WH, Ingle JN, Maihle NJ, Salisbury JL. Centrosome hypertrophy in human breast tumors: implications for genomic stability and cell polarity. Proc Natl Acad Sci U S A. 1998;95:2950-2955.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 2950-2955
-
-
Lingle, W.L.1
Lutz, W.H.2
Ingle, J.N.3
Maihle, N.J.4
Salisbury, J.L.5
-
5
-
-
0032170033
-
Centrosome defects and genetic instability in malignant tumors
-
Pihan GA, Purohit A, Wallace J, et al. Centrosome defects and genetic instability in malignant tumors. Cancer Res. 1998;58:3974-3985.
-
(1998)
Cancer Res
, vol.58
, pp. 3974-3985
-
-
Pihan, G.A.1
Purohit, A.2
Wallace, J.3
-
6
-
-
0035266301
-
Centrosome defects can account for cellular and genetic changes that characterize prostate cancer progression
-
Pihan GA, Purohit A, Wallace J, Malhotra R, Liotta L, Doxsey SJ. Centrosome defects can account for cellular and genetic changes that characterize prostate cancer progression. Cancer Res. 2001;61:2212-2219.
-
(2001)
Cancer Res
, vol.61
, pp. 2212-2219
-
-
Pihan, G.A.1
Purohit, A.2
Wallace, J.3
Malhotra, R.4
Liotta, L.5
Doxsey, S.J.6
-
7
-
-
0032931205
-
Centrosome abnormalities in pancreatic ductal carcinoma
-
Sato N, Mizumoto K, Nakamura M, et al. Centrosome abnormalities in pancreatic ductal carcinoma. Clin Cancer Res. 1999;5:963-970.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 963-970
-
-
Sato, N.1
Mizumoto, K.2
Nakamura, M.3
-
8
-
-
21744458439
-
Centrosome aberrations in chronic myeloid leukemia correlate with stage of disease and chromosomal instability
-
Giehl M, Fabarius A, Frank O, et al. Centrosome aberrations in chronic myeloid leukemia correlate with stage of disease and chromosomal instability. Leukemia. 2005;19:1192-1197.
-
(2005)
Leukemia
, vol.19
, pp. 1192-1197
-
-
Giehl, M.1
Fabarius, A.2
Frank, O.3
-
9
-
-
11144354652
-
Gene expression patterns in acute myeloid leukemia correlate with centrosome aberrations and numerical chromosome changes
-
Neben K, Tews B, Wrobel G, et al. Gene expression patterns in acute myeloid leukemia correlate with centrosome aberrations and numerical chromosome changes. Oncogene. 2004;23:2379-2384.
-
(2004)
Oncogene
, vol.23
, pp. 2379-2384
-
-
Neben, K.1
Tews, B.2
Wrobel, G.3
-
10
-
-
1242281345
-
Excessive centrosome abnormalities without ongoing numerical chromosome instability in a Burkitt's lymphoma
-
Duensing S, Lee BH, Dal Cin P, Munger K. Excessive centrosome abnormalities without ongoing numerical chromosome instability in a Burkitt's lymphoma. Mol Cancer. 2003;2:30.
-
(2003)
Mol Cancer
, vol.2
, pp. 30
-
-
Duensing, S.1
Lee, B.H.2
Dal Cin, P.3
Munger, K.4
-
11
-
-
10744221244
-
Centrosome aberrations as a possible mechanism for chromosomal instability in non-Hodgkin's lymphoma
-
Kramer A, Schweizer S, Neben K, et al. Centrosome aberrations as a possible mechanism for chromosomal instability in non-Hodgkin's lymphoma. Leukemia. 2003;17:2207-2213.
-
(2003)
Leukemia
, vol.17
, pp. 2207-2213
-
-
Kramer, A.1
Schweizer, S.2
Neben, K.3
-
12
-
-
8844219643
-
Centrosome abnormalities in ALK-positive anaplastic large-cell lymphoma
-
Ventura RA, Martin-Subero JI, Knippschild U, et al. Centrosome abnormalities in ALK-positive anaplastic large-cell lymphoma. Leukemia. 2004;18:1910-1911.
-
(2004)
Leukemia
, vol.18
, pp. 1910-1911
-
-
Ventura, R.A.1
Martin-Subero, J.I.2
Knippschild, U.3
-
13
-
-
33646402309
-
Clinical implication of centrosome amplification in plasma cell neoplasm
-
Chng WJ, Ahmann GJ, Henderson K, et al. Clinical implication of centrosome amplification in plasma cell neoplasm. Blood. 2006;107:3669-3675.
-
(2006)
Blood
, vol.107
, pp. 3669-3675
-
-
Chng, W.J.1
Ahmann, G.J.2
Henderson, K.3
-
14
-
-
13444294239
-
Receptor for hyaluronan-mediated motility correlates with centrosome abnormalities in multiple myeloma and maintains mitotic integrity
-
Maxwell CA, Keats JJ, Belch AR, Pilarski LM, Reiman T. Receptor for hyaluronan-mediated motility correlates with centrosome abnormalities in multiple myeloma and maintains mitotic integrity. Cancer Res. 2005;65:850-860.
-
(2005)
Cancer Res
, vol.65
, pp. 850-860
-
-
Maxwell, C.A.1
Keats, J.J.2
Belch, A.R.3
Pilarski, L.M.4
Reiman, T.5
-
15
-
-
33745779502
-
The molecular classification of multiple myeloma
-
Zhan F, Huang Y, Colla S, et al. The molecular classification of multiple myeloma. Blood. 2006;108:2020-2028.
-
(2006)
Blood
, vol.108
, pp. 2020-2028
-
-
Zhan, F.1
Huang, Y.2
Colla, S.3
-
16
-
-
22044440425
-
Cyclin D dysregulation: An early and unifying pathogenic event in multiple myeloma
-
Bergsagel PL, Kuehl WM, Zhan F, Sawyer J, Barlogie B, Shaughnessy J Jr. Cyclin D dysregulation: an early and unifying pathogenic event in multiple myeloma. Blood. 2005;106:296-303.
-
(2005)
Blood
, vol.106
, pp. 296-303
-
-
Bergsagel, P.L.1
Kuehl, W.M.2
Zhan, F.3
Sawyer, J.4
Barlogie, B.5
Shaughnessy Jr, J.6
-
17
-
-
33745779502
-
The molecular classification of multiple myeloma
-
Zhan F, Huang Y, Colla S, et al. The molecular classification of multiple myeloma. Blood. 2006;108:2020-2028.
-
(2006)
Blood
, vol.108
, pp. 2020-2028
-
-
Zhan, F.1
Huang, Y.2
Colla, S.3
-
18
-
-
34147129816
-
Gene expression profiling and correlation with outcome in clinical trials of the proteasome inhibitor bortezomib
-
Mulligan G, Mitsiades C, Bryant B, et al. Gene expression profiling and correlation with outcome in clinical trials of the proteasome inhibitor bortezomib. Blood. 2007;109:3177-3188.
-
(2007)
Blood
, vol.109
, pp. 3177-3188
-
-
Mulligan, G.1
Mitsiades, C.2
Bryant, B.3
-
19
-
-
27344435774
-
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
-
Subramanian A, Tamayo P, Mootha VK, et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci U S A. 2005;102:15545-15550.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 15545-15550
-
-
Subramanian, A.1
Tamayo, P.2
Mootha, V.K.3
-
21
-
-
34247259822
-
Antitumor activity of MLN8054, an orally active small-molecule inhibitor of Aurora A kinase
-
Manfredi MG, Ecsedy JA, Meetze KA, et al. Antitumor activity of MLN8054, an orally active small-molecule inhibitor of Aurora A kinase. Proc Natl Acad Sci U S A. 2007;104:4106-4111.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 4106-4111
-
-
Manfredi, M.G.1
Ecsedy, J.A.2
Meetze, K.A.3
-
22
-
-
20444433230
-
Bortezomib or high-dose dexamethasone for relapsed multiple myeloma
-
Richardson PG, Sonneveld P, Schuster MW, et al. Bortezomib or high-dose dexamethasone for relapsed multiple myeloma. N Engl J Med. 2005;352:2487-2498.
-
(2005)
N Engl J Med
, vol.352
, pp. 2487-2498
-
-
Richardson, P.G.1
Sonneveld, P.2
Schuster, M.W.3
-
23
-
-
0037973279
-
A phase 2 study of bortezomib in relapsed, refractory myeloma
-
Richardson PG, Barlogie B, Berenson J, et al. A phase 2 study of bortezomib in relapsed, refractory myeloma. N Engl J Med. 2003;348:2609-2617.
-
(2003)
N Engl J Med
, vol.348
, pp. 2609-2617
-
-
Richardson, P.G.1
Barlogie, B.2
Berenson, J.3
-
24
-
-
33947217497
-
A validated gene expression model of high-risk multiple myeloma is defined by deregulated expression of genes mapping to chromosome 1
-
Shaughnessy JD Jr, Zhan F, Burington BE, et al. A validated gene expression model of high-risk multiple myeloma is defined by deregulated expression of genes mapping to chromosome 1. Blood. 2006;109:2276-2284.
-
(2006)
Blood
, vol.109
, pp. 2276-2284
-
-
Shaughnessy Jr, J.D.1
Zhan, F.2
Burington, B.E.3
-
25
-
-
33748286796
-
A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers
-
Carter SL, Eklund AC, Kohane IS, Harris LN, Szallasi Z. A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers. Nat Genet. 2006;38:1043-1048.
-
(2006)
Nat Genet
, vol.38
, pp. 1043-1048
-
-
Carter, S.L.1
Eklund, A.C.2
Kohane, I.S.3
Harris, L.N.4
Szallasi, Z.5
-
26
-
-
0036831681
-
Centrosome aberrations: Cause or consequence of cancer progression?
-
Nigg EA. Centrosome aberrations: cause or consequence of cancer progression? Nat Rev Cancer. 2002;2:815-825.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 815-825
-
-
Nigg, E.A.1
-
27
-
-
3943090500
-
The centrosome in normal and transformed cells
-
Wang Q, Hirohashi Y, Furuuchi K, et al. The centrosome in normal and transformed cells. DNA Cell Biol. 2004;23:475-489.
-
(2004)
DNA Cell Biol
, vol.23
, pp. 475-489
-
-
Wang, Q.1
Hirohashi, Y.2
Furuuchi, K.3
-
28
-
-
10344236486
-
Aurora-kinase inhibitors as anti-cancer agents
-
Keen N, Taylor S. Aurora-kinase inhibitors as anti-cancer agents. Nat Rev Cancer. 2004;4:927-936.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 927-936
-
-
Keen, N.1
Taylor, S.2
-
29
-
-
58049221353
-
Anti-myeloma activity of the small-molecule aurora kinase inhibitor VE465 [abstract]
-
Negri JM, Mcmillin DW, Mitsiades N, et al. Anti-myeloma activity of the small-molecule aurora kinase inhibitor VE465 [abstract]. Blood. 2006;108:3468.
-
(2006)
Blood
, vol.108
, pp. 3468
-
-
Negri, J.M.1
Mcmillin, D.W.2
Mitsiades, N.3
-
30
-
-
38349116712
-
Aurora kinases as therapeutic targets in multiple myeloma [abstract]
-
Reiman T, Evans RP, Naber C, et al. Aurora kinases as therapeutic targets in multiple myeloma [abstract]. Blood. 2006;108:847.
-
(2006)
Blood
, vol.108
, pp. 847
-
-
Reiman, T.1
Evans, R.P.2
Naber, C.3
-
31
-
-
34247393658
-
Targeting aurora kinases as therapy in multiple myeloma
-
Shi Y, Reiman T, Li W, et al. Targeting aurora kinases as therapy in multiple myeloma. Blood. 2007;109:3915-3921.
-
(2007)
Blood
, vol.109
, pp. 3915-3921
-
-
Shi, Y.1
Reiman, T.2
Li, W.3
-
33
-
-
0037586498
-
AURORA-A amplification overrides the mitotic spindle assembly checkpoint, inducing resistance to Taxol
-
Anand S, Penrhyn-Lowe S, Venkitaraman AR. AURORA-A amplification overrides the mitotic spindle assembly checkpoint, inducing resistance to Taxol. Cancer Cell. 2003;3:51-62.
-
(2003)
Cancer Cell
, vol.3
, pp. 51-62
-
-
Anand, S.1
Penrhyn-Lowe, S.2
Venkitaraman, A.R.3
-
34
-
-
0345304925
-
AuroraA overexpression overrides the mitotic spindle checkpoint triggered by nocodazole, a microtubule destabilizer
-
Jiang Y, Zhang Y, Lees E, Seghezzi W. AuroraA overexpression overrides the mitotic spindle checkpoint triggered by nocodazole, a microtubule destabilizer. Oncogene. 2003;22:8293-8301.
-
(2003)
Oncogene
, vol.22
, pp. 8293-8301
-
-
Jiang, Y.1
Zhang, Y.2
Lees, E.3
Seghezzi, W.4
-
35
-
-
9144251019
-
Phosphorylation by aurora kinase A induces Mdm2-mediated destabilization and inhibition of p53
-
Katayama H, Sasai K, Kawai H, et al. Phosphorylation by aurora kinase A induces Mdm2-mediated destabilization and inhibition of p53. Nat Genet. 2004;36:55-62.
-
(2004)
Nat Genet
, vol.36
, pp. 55-62
-
-
Katayama, H.1
Sasai, K.2
Kawai, H.3
-
36
-
-
11144228109
-
Estrogen mediates Aurora-A overexpression, centrosome amplification, chromosomal instability, and breast cancer in female ACI rats
-
Li JJ, Weroha SJ, Lingle WL, Papa D, Salisbury JL, Li SA. Estrogen mediates Aurora-A overexpression, centrosome amplification, chromosomal instability, and breast cancer in female ACI rats. Proc Natl Acad Sci U S A. 2004;101:18123-18128.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 18123-18128
-
-
Li, J.J.1
Weroha, S.J.2
Lingle, W.L.3
Papa, D.4
Salisbury, J.L.5
Li, S.A.6
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