-
2
-
-
84860459037
-
Pathophysiology of myeloma bone disease
-
Gahrton G, Durie BGM, Samson DM, eds, London: Arnold
-
Oyajobi BO, Mundy GR. Pathophysiology of myeloma bone disease. In: Gahrton G, Durie BGM, Samson DM, eds. Multiple Myeloma and Related Disorders. London: Arnold, 2004:74-88.
-
(2004)
Multiple Myeloma and Related Disorders
, pp. 74-88
-
-
Oyajobi, B.O.1
Mundy, G.R.2
-
3
-
-
0032512903
-
Myeloma bone disease
-
Mundy GR. Myeloma bone disease. Eur J Cancer 1998;34:246-251.
-
(1998)
Eur J Cancer
, vol.34
, pp. 246-251
-
-
Mundy, G.R.1
-
5
-
-
0025885099
-
Role of bone marrow stromal cells in the growth of human multiple myeloma
-
Caligaris-Cappio F, Bergui L, Gregoretti MG et al. Role of bone marrow stromal cells in the growth of human multiple myeloma. Blood 1991;77: 2688-2693.
-
(1991)
Blood
, vol.77
, pp. 2688-2693
-
-
Caligaris-Cappio, F.1
Bergui, L.2
Gregoretti, M.G.3
-
6
-
-
64049103764
-
-
Terpos E, Politou M, Rahemtulla A. New insights into the pathophysiology
-
Terpos E, Politou M, Rahemtulla A. New insights into the pathophysiology
-
-
-
-
7
-
-
0346219279
-
-
and management of bone disease in multiple myeloma. Br J Haematol 2003;123:758-769.
-
and management of bone disease in multiple myeloma. Br J Haematol 2003;123:758-769.
-
-
-
-
8
-
-
0036829305
-
Role ofthe bone marrow microenvironmentin multiple myeloma
-
Roodman GD. Role ofthe bone marrow microenvironmentin multiple myeloma. J Bone Miner Res 2002;17:1921-1925.
-
(2002)
J Bone Miner Res
, vol.17
, pp. 1921-1925
-
-
Roodman, G.D.1
-
9
-
-
33751193178
-
Multiple myeloma bone disease: Pathophysiology of osteoblast inhibition
-
Giuliani N, Rizzoli V, Roodman GD. Multiple myeloma bone disease: Pathophysiology of osteoblast inhibition. Blood 2006;108:3992-3996.
-
(2006)
Blood
, vol.108
, pp. 3992-3996
-
-
Giuliani, N.1
Rizzoli, V.2
Roodman, G.D.3
-
10
-
-
0022476624
-
Importance of quantitative histology of bone changes in monoclonal gammopathy
-
Bataille R, Chappard D, Alexandre C et al. Importance of quantitative histology of bone changes in monoclonal gammopathy. Br J Cancer 1986;53: 805-810.
-
(1986)
Br J Cancer
, vol.53
, pp. 805-810
-
-
Bataille, R.1
Chappard, D.2
Alexandre, C.3
-
11
-
-
14644420230
-
The role of markers of bone remodeling in multiple myeloma
-
Terpos E, Politou M, Rahemtulla A. The role of markers of bone remodeling in multiple myeloma. Blood Rev 2005;19:125-142.
-
(2005)
Blood Rev
, vol.19
, pp. 125-142
-
-
Terpos, E.1
Politou, M.2
Rahemtulla, A.3
-
12
-
-
33845193025
-
Myeloma bone disease: Patho-genetic mechanisms and clinical assessment
-
Silvestris F, Lombardi L, De Matteo M et al. Myeloma bone disease: Patho-genetic mechanisms and clinical assessment. Leuk Res 2007;31:129 -138.
-
(2007)
Leuk Res
, vol.31
, pp. 129-138
-
-
Silvestris, F.1
Lombardi, L.2
De Matteo, M.3
-
13
-
-
0141482103
-
Receptor activator of nuclear factor kappaB ligand expression by human myeloma cells mediates osteoclast formation in vitro and correlates with bone destruction in vivo
-
Farrugia AN, Atkins GJ, To LB et al. Receptor activator of nuclear factor kappaB ligand expression by human myeloma cells mediates osteoclast formation in vitro and correlates with bone destruction in vivo. Cancer Res 2003;63:5438-5445.
-
(2003)
Cancer Res
, vol.63
, pp. 5438-5445
-
-
Farrugia, A.N.1
Atkins, G.J.2
To, L.B.3
-
14
-
-
3242662500
-
Myeloma cells can directly contribute to the pool of RANKL in bone bypassing the classic stromal and osteoblastpathwayofosteoclaststimulation
-
Lai FP, Cole-Sinclair M, Cheng WJ et al. Myeloma cells can directly contribute to the pool of RANKL in bone bypassing the classic stromal and osteoblastpathwayofosteoclaststimulation. Br J Haematol 2004;126:192-201.
-
(2004)
Br J Haematol
, vol.126
, pp. 192-201
-
-
Lai, F.P.1
Cole-Sinclair, M.2
Cheng, W.J.3
-
15
-
-
4644261592
-
Mechanisms of bone metastasis
-
Roodman GD. Mechanisms of bone metastasis. N Engl J Med 2004;350: 1655-1664.
-
(2004)
N Engl J Med
, vol.350
, pp. 1655-1664
-
-
Roodman, G.D.1
-
16
-
-
0020960066
-
Direct bone resorbing activity of murine myeloma cells
-
McDonald DF, Schofield BH, Prezioso EM et al. Direct bone resorbing activity of murine myeloma cells. Cancer Lett 1983;19:119-124.
-
(1983)
Cancer Lett
, vol.19
, pp. 119-124
-
-
McDonald, D.F.1
Schofield, B.H.2
Prezioso, E.M.3
-
17
-
-
33846201640
-
Osteoclast nuclei of myeloma patients show chromosome translocations specific for the myeloma cell clone: Anew type of cancer-host partnership?
-
Andersen TL, Boissy P, Sondergaard TE et al. Osteoclast nuclei of myeloma patients show chromosome translocations specific for the myeloma cell clone: Anew type of cancer-host partnership? J Pathol 2007;211:10-17.
-
(2007)
J Pathol
, vol.211
, pp. 10-17
-
-
Andersen, T.L.1
Boissy, P.2
Sondergaard, T.E.3
-
18
-
-
27244441444
-
Functional osteoclast-like transformation of cultured human myeloma cell lines
-
Calvani N, Cafforio P, Silvestris F et al. Functional osteoclast-like transformation of cultured human myeloma cell lines. Br J Haematol 2005;130: 926-938.
-
(2005)
Br J Haematol
, vol.130
, pp. 926-938
-
-
Calvani, N.1
Cafforio, P.2
Silvestris, F.3
-
19
-
-
0035808458
-
Tumor necrosis factor-alpha (TNF) stimulates RANKL-induced osteoclastogenesis viacoupling ofTNF type 1 receptor and RANK signaling pathways
-
Zhang YH, Heulsmann A, Tondravi MM et al. Tumor necrosis factor-alpha (TNF) stimulates RANKL-induced osteoclastogenesis viacoupling ofTNF type 1 receptor and RANK signaling pathways. J Biol Chem 2001;276: 563-568.
-
(2001)
J Biol Chem
, vol.276
, pp. 563-568
-
-
Zhang, Y.H.1
Heulsmann, A.2
Tondravi, M.M.3
-
20
-
-
31044436261
-
M-CSF mediates TNF-induced inflammatory osteolysis
-
Kitaura H, Zhou P, Kim HJ et al. M-CSF mediates TNF-induced inflammatory osteolysis. J Clin Invest 2005;115:3418-3427.
-
(2005)
J Clin Invest
, vol.115
, pp. 3418-3427
-
-
Kitaura, H.1
Zhou, P.2
Kim, H.J.3
-
21
-
-
0037443533
-
RANK ligand and osteoprotegerin in myeloma bone disease
-
Sezer O, Heider U, Zavrski I et al. RANK ligand and osteoprotegerin in myeloma bone disease. Blood 2003;101:2094-2098.
-
(2003)
Blood
, vol.101
, pp. 2094-2098
-
-
Sezer, O.1
Heider, U.2
Zavrski, I.3
-
22
-
-
0037108435
-
Osteoprotegerin is bound, internalized, and degraded by multiple myeloma cells
-
Standal T, Seidel C, Hjertner 0 et al. Osteoprotegerin is bound, internalized, and degraded by multiple myeloma cells. Blood 2002;100:3002-3007.
-
(2002)
Blood
, vol.100
, pp. 3002-3007
-
-
Standal, T.1
Seidel, C.2
Hjertner 03
-
23
-
-
0035496947
-
Nordic Myeloma Study Group. Serum osteoprotegerin levels are reduced in patients with multiple myeloma with lytic bone disease
-
Seidel C, Hjertner 0, Abildgaard N et al.; Nordic Myeloma Study Group. Serum osteoprotegerin levels are reduced in patients with multiple myeloma with lytic bone disease. Blood 2001;98:2269-2271.
-
(2001)
Blood
, vol.98
, pp. 2269-2271
-
-
Seidel, C.1
Hjertner 02
Abildgaard, N.3
-
24
-
-
0043245842
-
Soluble receptor activator ofnuclear factor κB ligand-osteoprotegerin ratio predicts survival in multiple myeloma: Proposal fora novel prognostic index
-
Terpos E, Szydlo R, Apperley JF et al. Soluble receptor activator ofnuclear factor κB ligand-osteoprotegerin ratio predicts survival in multiple myeloma: Proposal fora novel prognostic index. Blood 2003;102:1064-1069.
-
(2003)
Blood
, vol.102
, pp. 1064-1069
-
-
Terpos, E.1
Szydlo, R.2
Apperley, J.F.3
-
25
-
-
4544360663
-
Role ofreceptoractivatorof nuclear factor-kappa B ligand (RANKL), osteoprotegerin and macrophage protein 1-alpha (MIP-1a) in monoclonal gammopathy of undetermined significance (MGUS)
-
Politou M, Terpos E, Anagnostopoulos A et al. Role ofreceptoractivatorof nuclear factor-kappa B ligand (RANKL), osteoprotegerin and macrophage protein 1-alpha (MIP-1a) in monoclonal gammopathy of undetermined significance (MGUS). Br J Haematol 2004;126:686-689.
-
(2004)
Br J Haematol
, vol.126
, pp. 686-689
-
-
Politou, M.1
Terpos, E.2
Anagnostopoulos, A.3
-
26
-
-
4143119930
-
Impaired osteoblastogenesis in myeloma bone disease: Role of upregulated apoptosis by cytokines and malignant plasma cells
-
Silvestris F, Cafforio P, Calvani N et al. Impaired osteoblastogenesis in myeloma bone disease: Role of upregulated apoptosis by cytokines and malignant plasma cells. Br J Haematol 2004;126:475-486.
-
(2004)
Br J Haematol
, vol.126
, pp. 475-486
-
-
Silvestris, F.1
Cafforio, P.2
Calvani, N.3
-
27
-
-
0346363760
-
The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma
-
Tian E, Zhan F, Walker R et al. The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma. N Engl J Med 2003;349:2483-2494.
-
(2003)
N Engl J Med
, vol.349
, pp. 2483-2494
-
-
Tian, E.1
Zhan, F.2
Walker, R.3
-
28
-
-
0345534770
-
Hepatocyte growthfactor (HGF) induces interleukin-11 secretion from osteoblasts: A possible role for HGF in myeloma-associated osteolytic bone disease
-
Hjertner O, Torgersen ML, Seidel C et al. Hepatocyte growthfactor (HGF) induces interleukin-11 secretion from osteoblasts: A possible role for HGF in myeloma-associated osteolytic bone disease. Blood 1999;94:3883-3888.
-
(1999)
Blood
, vol.94
, pp. 3883-3888
-
-
Hjertner, O.1
Torgersen, M.L.2
Seidel, C.3
-
29
-
-
0033034054
-
Potential role ofinsulin-like growthfac- tor binding protein-4 in the uncoupling of bone turnover in multiple myeloma
-
Feliers D, WoodruffK, Abboud S. Potential role ofinsulin-like growthfac- tor binding protein-4 in the uncoupling of bone turnover in multiple myeloma. Br J Haematol 1999;104:715-722.
-
(1999)
Br J Haematol
, vol.104
, pp. 715-722
-
-
Feliers, D.1
Woodruff, K.2
Abboud, S.3
-
30
-
-
33745219872
-
Myeloma and bone disease: "The dangerous tango."Clin Adv
-
Epstein J, Walker R. Myeloma and bone disease: "The dangerous tango."Clin Adv Hematol Oncol 2006;4:300-306.
-
(2006)
Hematol Oncol
, vol.4
, pp. 300-306
-
-
Epstein, J.1
Walker, R.2
-
31
-
-
0015915188
-
The cellular basis of metabolic bone disease
-
Rasmussen H, Bordier P. The cellular basis of metabolic bone disease. N Engl J Med 1973;289:25-32.
-
(1973)
N Engl J Med
, vol.289
, pp. 25-32
-
-
Rasmussen, H.1
Bordier, P.2
-
32
-
-
0016811449
-
Bone resorption restored in osteopetrotic mice by transplants of normal bone marrow and spleen cells
-
Walker DG. Bone resorption restored in osteopetrotic mice by transplants of normal bone marrow and spleen cells. Science 1975;190:784-785.
-
(1975)
Science
, vol.190
, pp. 784-785
-
-
Walker, D.G.1
-
33
-
-
0023928381
-
Osteoclast-like cell formation and its regulation by osteotropic hormones in mouse bone marrow cultures
-
Takahashi N, Yamana H, Yoshiki S et al. Osteoclast-like cell formation and its regulation by osteotropic hormones in mouse bone marrow cultures. Endocrinology 1988;122:1373-1382.
-
(1988)
Endocrinology
, vol.122
, pp. 1373-1382
-
-
Takahashi, N.1
Yamana, H.2
Yoshiki, S.3
-
34
-
-
0031005576
-
Osteoprotegerin: A novel secreted protein involved in the regulation of bone density
-
Simonet WS, Lacey DL, Dunstan CR et al. Osteoprotegerin: A novel secreted protein involved in the regulation of bone density. Cell 1997;89: 309 -319.
-
(1997)
Cell
, vol.89
, pp. 309-319
-
-
Simonet, W.S.1
Lacey, D.L.2
Dunstan, C.R.3
-
35
-
-
0031439265
-
TRANCE (tumor necrosis factor [TNF]- related activation-induced cytokine), a new TNF family member predominantly expressed inTcells, is a dendriticcell-specificsurvival factor
-
Wong BR, Josien R, Lee SY et al. TRANCE (tumor necrosis factor [TNF]- related activation-induced cytokine), a new TNF family member predominantly expressed inTcells, is a dendriticcell-specificsurvival factor. J Exp Med 1997;186:2075-2080.
-
(1997)
J Exp Med
, vol.186
, pp. 2075-2080
-
-
Wong, B.R.1
Josien, R.2
Lee, S.Y.3
-
36
-
-
0032540319
-
Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation
-
Lacey DL, Timms E, Tan HL et al. Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation. Cell 1998;93:165-176.
-
(1998)
Cell
, vol.93
, pp. 165-176
-
-
Lacey, D.L.1
Timms, E.2
Tan, H.L.3
-
37
-
-
0037673945
-
Osteoclast differentiation and activation
-
Boyle WJ, Simonet WS, Lacey DL. Osteoclast differentiation and activation. Nature 2003;423:337-342.
-
(2003)
Nature
, vol.423
, pp. 337-342
-
-
Boyle, W.J.1
Simonet, W.S.2
Lacey, D.L.3
-
38
-
-
0025332897
-
The murine mutation osteopetro- sis is in the coding region of the macrophage colony stimulating factor gene
-
Yoshida H, Hayashi SI, Kunisada T et al. The murine mutation osteopetro- sis is in the coding region of the macrophage colony stimulating factor gene. Nature 1990;345:442-444.
-
(1990)
Nature
, vol.345
, pp. 442-444
-
-
Yoshida, H.1
Hayashi, S.I.2
Kunisada, T.3
-
39
-
-
11144355389
-
The immunomodulatory adapter proteins DAP12 and Fc receptor gamma-chain (FcRy) regulate development of functional osteoclasts through the Syk tyrosine kinase
-
Mocsai A, Humphrey MB, Van Ziffle JA et al. The immunomodulatory adapter proteins DAP12 and Fc receptor gamma-chain (FcRy) regulate development of functional osteoclasts through the Syk tyrosine kinase. Proc Natl Acad SciUSA 2004;101:6158-6163.
-
(2004)
Proc Natl Acad SciUSA
, vol.101
, pp. 6158-6163
-
-
Mocsai, A.1
Humphrey, M.B.2
Van Ziffle, J.A.3
-
40
-
-
11144354330
-
Costimulatory signals mediated by the ITAM motif cooperate with RANKL for bone homeostasis
-
KogaT, Inui M, Inoue K et al. Costimulatory signals mediated by the ITAM motif cooperate with RANKL for bone homeostasis. Nature 2004;428: 758 -763.
-
(2004)
Nature
, vol.428
, pp. 758-763
-
-
Koga, T.1
Inui, M.2
Inoue, K.3
-
41
-
-
85047685623
-
TNFalpha potently activates oste- oclasts, througha direct action independentofand strongly synergistic with RANKL
-
Fuller K, Murphy C, Kirstein B et al. TNFalpha potently activates oste- oclasts, througha direct action independentofand strongly synergistic with RANKL. Endocrinology 2002;143:1108 -1118.
-
(2002)
Endocrinology
, vol.143
, pp. 1108-1118
-
-
Fuller, K.1
Murphy, C.2
Kirstein, B.3
-
42
-
-
0034523328
-
TNF-alpha induces osteoclastogenesis by direct stimulation of macrophages exposed to permissive levels of RANK ligand
-
Lam J, Takeshita S, Barker JE et al. TNF-alpha induces osteoclastogenesis by direct stimulation of macrophages exposed to permissive levels of RANK ligand. J Clin Invest 2000;106:1481-1488.
-
(2000)
J Clin Invest
, vol.106
, pp. 1481-1488
-
-
Lam, J.1
Takeshita, S.2
Barker, J.E.3
-
43
-
-
0041731907
-
-
Faccio R, Novack DV, Zallone A et al. Dynamic changes in the osteoclast cytoskeleton in response to growth factors and cell attachment are controlled by β3 integrin. J Cell Biol 2003;162:499-509.
-
Faccio R, Novack DV, Zallone A et al. Dynamic changes in the osteoclast cytoskeleton in response to growth factors and cell attachment are controlled by β3 integrin. J Cell Biol 2003;162:499-509.
-
-
-
-
44
-
-
0033621890
-
Mice lacking β3 integrins are osteosclerotic because of dysfunctional osteoclasts
-
McHugh KP, Hodivala-Dilke K, Zheng MH et al. Mice lacking β3 integrins are osteosclerotic because of dysfunctional osteoclasts. J Clin Invest 2000; 105:433-440.
-
(2000)
J Clin Invest
, vol.105
, pp. 433-440
-
-
McHugh, K.P.1
Hodivala-Dilke, K.2
Zheng, M.H.3
-
45
-
-
33748107509
-
Role of DC-STAMP in cellular fusion of osteoclasts and macrophage giant cells
-
Yagi M, Miyamoto T, Toyama Y et al. Role of DC-STAMP in cellular fusion of osteoclasts and macrophage giant cells. J Bone Miner Metab 2006; 24:355-358.
-
(2006)
J Bone Miner Metab
, vol.24
, pp. 355-358
-
-
Yagi, M.1
Miyamoto, T.2
Toyama, Y.3
-
47
-
-
34548248999
-
Induction of DC-STAMP by alternative activation and downstream signalling mechanisms
-
Yagi M, Ninomiya K, Fujita N et al. Induction of DC-STAMP by alternative activation and downstream signalling mechanisms. J Bone Miner Res 2007;22:992-1001.
-
(2007)
J Bone Miner Res
, vol.22
, pp. 992-1001
-
-
Yagi, M.1
Ninomiya, K.2
Fujita, N.3
-
48
-
-
23744459835
-
DC-STAMP is essential for cell-cell fusion in osteoclasts and foreign body giant cells
-
Yagi M, Miyamoto T, Sawatani Y et al. DC-STAMP is essential for cell-cell fusion in osteoclasts and foreign body giant cells. J Exp Med 2005;202: 345-351.
-
(2005)
J Exp Med
, vol.202
, pp. 345-351
-
-
Yagi, M.1
Miyamoto, T.2
Sawatani, Y.3
-
49
-
-
0141707692
-
Serum levels of macrophage inflammatory protein-1 alpha (MIP-1α) correlate with the extent of bone disease and survival in patients with multiple myeloma
-
Terpos E, Politou M, Szydlo R et al. Serum levels of macrophage inflammatory protein-1 alpha (MIP-1α) correlate with the extent of bone disease and survival in patients with multiple myeloma. Br J Haematol 2003;123: 106 -109.
-
(2003)
Br J Haematol
, vol.123
, pp. 106-109
-
-
Terpos, E.1
Politou, M.2
Szydlo, R.3
-
50
-
-
16844377831
-
Mechanistic insight into osteoclast differentiation in osteo-immunology
-
Takayanagi H. Mechanistic insight into osteoclast differentiation in osteo-immunology. J Mol Med 2005;83:170-179.
-
(2005)
J Mol Med
, vol.83
, pp. 170-179
-
-
Takayanagi, H.1
-
51
-
-
33644558753
-
Inhibitory effects ofosteoblasts and increased bone formation on myeloma in novel culture systems and a myelomatous mouse model
-
Yaccoby S, WezemanMJ, Zangari M et al. Inhibitory effects ofosteoblasts and increased bone formation on myeloma in novel culture systems and a myelomatous mouse model. Haematologica 2006;91:192-199.
-
(2006)
Haematologica
, vol.91
, pp. 192-199
-
-
Yaccoby, S.1
Wezeman, M.J.2
Zangari, M.3
-
52
-
-
0030728888
-
Non-secretory multiple myeloma with multinucleated giant plasma cells
-
Ghevaert C, Fournier M, Bernardi F et al. Non-secretory multiple myeloma with multinucleated giant plasma cells. Leuk Lymphoma 1997;27:185- 189.
-
(1997)
Leuk Lymphoma
, vol.27
, pp. 185-189
-
-
Ghevaert, C.1
Fournier, M.2
Bernardi, F.3
-
53
-
-
0025267281
-
Plasma cell myeloma with cleaved, multilobated, and monocytoid nuclei
-
Zukerberg LR, Ferry JA, Conlon M et al. Plasma cell myeloma with cleaved, multilobated, and monocytoid nuclei. Am J Clin Pathol 1990;93: 657-661.
-
(1990)
Am J Clin Pathol
, vol.93
, pp. 657-661
-
-
Zukerberg, L.R.1
Ferry, J.A.2
Conlon, M.3
-
54
-
-
0024371883
-
Ultrastructure of multinucleated giant myeloma cells: Report of one case
-
Kurabayashi H, Miyawaki S, Murakami H et al. Ultrastructure of multinucleated giant myeloma cells: Report of one case. Am J Hematol 1989;31: 284-285.
-
(1989)
Am J Hematol
, vol.31
, pp. 284-285
-
-
Kurabayashi, H.1
Miyawaki, S.2
Murakami, H.3
-
56
-
-
0024549325
-
Myelomonocytic myeloma cell line (LB 84-1)
-
Durie BGM, Grogan TM, Spier C et al. Myelomonocytic myeloma cell line (LB 84-1). Blood 1989;73:770-776.
-
(1989)
Blood
, vol.73
, pp. 770-776
-
-
Durie, B.G.M.1
Grogan, T.M.2
Spier, C.3
-
57
-
-
0024505031
-
Phenotypic analysis of human myeloma cell lines
-
Duperray C, Klein B, Durie BGM et al. Phenotypic analysis of human myeloma cell lines. Blood 1989;73:566-572.
-
(1989)
Blood
, vol.73
, pp. 566-572
-
-
Duperray, C.1
Klein, B.2
Durie, B.G.M.3
-
58
-
-
33846653850
-
Induction of multilineage markers in human myeloma cells and their down-regulation by interleukin 6
-
Liu S, Otsuyama K, Ma Z et al. Induction of multilineage markers in human myeloma cells and their down-regulation by interleukin 6. Int J Hematol 2007;85:49-58.
-
(2007)
Int J Hematol
, vol.85
, pp. 49-58
-
-
Liu, S.1
Otsuyama, K.2
Ma, Z.3
-
59
-
-
0037082473
-
Negative regulation of erythroblast maturation by Fas-L( + )/TRAIL( +) highly malignant plasma cells: A major pathogenetic mechanism of anemia in multiple myeloma
-
Silvestris F, Cafforio P, Tucci M et al. Negative regulation of erythroblast maturation by Fas-L( + )/TRAIL( +) highly malignant plasma cells: A major pathogenetic mechanism of anemia in multiple myeloma. Blood 2002; 99:1305-1313.
-
(2002)
Blood
, vol.99
, pp. 1305-1313
-
-
Silvestris, F.1
Cafforio, P.2
Tucci, M.3
-
60
-
-
0032890449
-
Osteoclast markers accumulate on cells developing from human peripheral blood mononuclear precursors
-
Faust J, Lacey DL, Hunt P et al. Osteoclast markers accumulate on cells developing from human peripheral blood mononuclear precursors. J Cell Biochem 1999;72:67-80.
-
(1999)
J Cell Biochem
, vol.72
, pp. 67-80
-
-
Faust, J.1
Lacey, D.L.2
Hunt, P.3
-
61
-
-
39049101272
-
Expression and function of the calcitonin receptor by myeloma cells in their osteoclast-like activity in vitro
-
Silvestris F, Cafforio P, De Matteo M et al. Expression and function of the calcitonin receptor by myeloma cells in their osteoclast-like activity in vitro. Leuk Res 2008;32:611-623.
-
(2008)
Leuk Res
, vol.32
, pp. 611-623
-
-
Silvestris, F.1
Cafforio, P.2
De Matteo, M.3
-
62
-
-
33750448666
-
In-vitro functional phenotypes of plasma cell lines from patients with multiple myeloma
-
Silvestris F, Cafforio P, Calvani N et al. In-vitro functional phenotypes of plasma cell lines from patients with multiple myeloma. Leuk Lymphoma 2006;47:1921-1931.
-
(2006)
Leuk Lymphoma
, vol.47
, pp. 1921-1931
-
-
Silvestris, F.1
Cafforio, P.2
Calvani, N.3
-
63
-
-
0018120428
-
Directresorption of bone by human breast cancer cells in vitro
-
Eilon G, Mundy GR. Directresorption of bone by human breast cancer cells in vitro. Nature 1978;276:726-728.
-
(1978)
Nature
, vol.276
, pp. 726-728
-
-
Eilon, G.1
Mundy, G.R.2
-
64
-
-
0030747949
-
Direct osteolysis induced by metastatic murine melanoma cells: Role of matrix metalloproteinases
-
Sanchez-Sweatman OH, Lee J, Orr FW et al. Direct osteolysis induced by metastatic murine melanoma cells: Role of matrix metalloproteinases. Eur J Cancer 1997;33:918-925.
-
(1997)
Eur J Cancer
, vol.33
, pp. 918-925
-
-
Sanchez-Sweatman, O.H.1
Lee, J.2
Orr, F.W.3
-
65
-
-
0030791806
-
Mechanisms of bone lesions in multiple myeloma and lymphoma
-
Roodman GD. Mechanisms of bone lesions in multiple myeloma and lymphoma. Cancer 1997;80:1557-1563.
-
(1997)
Cancer
, vol.80
, pp. 1557-1563
-
-
Roodman, G.D.1
-
66
-
-
3343001310
-
Evidence of a role for RANKL in the development of myeloma bone disease
-
De Leenheer E, Mueller GS, Vanderkerken K et al. Evidence of a role for RANKL in the development of myeloma bone disease. Curr Opin Pharmacol 2004;4:340-346.
-
(2004)
Curr Opin Pharmacol
, vol.4
, pp. 340-346
-
-
De Leenheer, E.1
Mueller, G.S.2
Vanderkerken, K.3
-
67
-
-
0026728085
-
The relationshipbetweenthe numberofnuclei of an osteoclast and its resorptive capability in vitro
-
PiperK, Boyde A, Jones SJ. The relationshipbetweenthe numberofnuclei of an osteoclast and its resorptive capability in vitro. Anat Embryol (Berl) 1992;186:291-299.
-
(1992)
Anat Embryol (Berl)
, vol.186
, pp. 291-299
-
-
Piper, K.1
Boyde, A.2
Jones, S.J.3
-
68
-
-
0035128622
-
Resorptive state and cell size influence intracellular pH regulation in rabbit osteoclasts cultured on collagen-hydroxyapatite films
-
Lees RL, Sabharwal VK, Heersche JNM. Resorptive state and cell size influence intracellular pH regulation in rabbit osteoclasts cultured on collagen-hydroxyapatite films. Bone 2001;28:187-194.
-
(2001)
Bone
, vol.28
, pp. 187-194
-
-
Lees, R.L.1
Sabharwal, V.K.2
Heersche, J.N.M.3
-
69
-
-
2542455620
-
Stepwise reprogramming of B cells into mac-rophages
-
Xie HF, Ye M, Feng R et al. Stepwise reprogramming of B cells into mac-rophages. Cell 2004;117:663-676.
-
(2004)
Cell
, vol.117
, pp. 663-676
-
-
Xie, H.F.1
Ye, M.2
Feng, R.3
-
70
-
-
34548559114
-
Targeting MEK1/2 blocks osteoclast differentiation, function and cytokine secretion in multiple myeloma
-
Breitkreutz I, Raab MS, Vallet S et al. Targeting MEK1/2 blocks osteoclast differentiation, function and cytokine secretion in multiple myeloma. Br J Haematol 2007;139:55-63.
-
(2007)
Br J Haematol
, vol.139
, pp. 55-63
-
-
Breitkreutz, I.1
Raab, M.S.2
Vallet, S.3
-
71
-
-
64049112545
-
AlphaVBeta3 + (AvB3) adhesion molecule drives the osteoclast (OC)-like functional differentiation of myeloma cells
-
Presented at the, Greece, June 25-30
-
Lombardi L, Tucci L, Quatraro C et al. AlphaVBeta3 + (AvB3) adhesion molecule drives the osteoclast (OC)-like functional differentiation of myeloma cells. Presented at the XI International Myeloma Workshop, Kos Island, Greece, June 25-30, 2007.
-
(2007)
XI International Myeloma Workshop, Kos Island
-
-
Lombardi, L.1
Tucci, L.2
Quatraro, C.3
-
72
-
-
0037817454
-
Spontaneously formed tumori- genic hybrids of Meth A sarcoma cells and macrophages in vivo
-
Busund LTR, Killie MK, Bartnes K et al. Spontaneously formed tumori- genic hybrids of Meth A sarcoma cells and macrophages in vivo. Int J Cancer 2003;106:153-159.
-
(2003)
Int J Cancer
, vol.106
, pp. 153-159
-
-
Busund, L.T.R.1
Killie, M.K.2
Bartnes, K.3
-
73
-
-
0028270892
-
New model for bone resorption study in vitro: Human osteoclast-like cells from giant cell tumors of bone
-
Grano M, Colucci S, De Bellis M et al. New model for bone resorption study in vitro: Human osteoclast-like cells from giant cell tumors of bone. J Bone Miner Res 1994;9:1013-1020.
-
(1994)
J Bone Miner Res
, vol.9
, pp. 1013-1020
-
-
Grano, M.1
Colucci, S.2
De Bellis, M.3
|