3D MI-DRAGON: New model for the reconstruction of US FDA drug- target network and theoretical-experimental studies of inhibitors of rasagiline derivatives for AChE

Current Topics in Medicinal Chemistry

Volumn 12, Issue 16, 2012, Pages 1843-1865

  Prado Prado, Francisco ^a,c   García Mera, Xerardo ^a   Escobar, Manuel ^a   Alonso, Nerea ^a   Caamaño, Olga ^a   Yañez, Matilde ^b   González Díaz, Humberto ^b  

^a UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^b Financial and Tributary Law Area   (Spain)

^c UNIVERSIDAD DE QUINTANA ROO   (Mexico)

Author keywords

AChE inhibitors; Drug protein interaction complex networks; Markov model; Multi target QSAR; Protein structure networks

Indexed keywords

ACETYLCHOLINESTERASE; LIGAND; MALONYL COENZYME A DECARBOXYLASE; PROTEIN; RASAGILINE;

ARTICLE; ARTIFICIAL NEURAL NETWORK; BIOLOGICAL ACTIVITY; COMPARATIVE MOLECULAR FIELD ANALYSIS; COMPARATIVE MOLECULAR SIMILARITY INDICES ANALYSIS; COMPUTER MODEL; COMPUTER PREDICTION; COMPUTER PROGRAM; DRUG ANALYSIS; DRUG DATABASE; DRUG DESIGN; DRUG PROTEIN BINDING; EXPERIMENTAL STUDY; HUMAN; KINETICS; LDA MODEL; MEASUREMENT ACCURACY; MOLECULAR DOCKING; PARAMETERS; PERCEPTRON; PKA; PROTEIN STRUCTURE; QUANTITATIVE STRUCTURE ACTIVITY RELATION; SENSITIVITY AND SPECIFICITY; THEORETICAL STUDY;

CHOLINESTERASE INHIBITORS; INDANS; MODELS, THEORETICAL; UNITED STATES; UNITED STATES FOOD AND DRUG ADMINISTRATION;

EID: 84875359061     PISSN: 15680266     EISSN: 18734294     Source Type: Journal    
DOI: 10.2174/156802612803989228     Document Type: Article

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