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Volumn 67, Issue 1, 2010, Pages 17-27

The M-superfamily of conotoxins: A review

Author keywords

Conotoxin; M superfamily; Marine snail; Peptide; Review; Venom

Indexed keywords

ANALGESIC AGENT; CALCIUM CHANNEL BLOCKING AGENT; CODEINE; CONOTOXIN; CYSTEINE; CYSTINE; KAPPA M CONOTOXIN; M PROTEIN; M SUPERFAMILY PEPTIDE; MARINE TOXIN; MORPHINE; MU CONOTOXIN; OMEGA CONOTOXIN MVIIA; OPIATE DERIVATIVE; PEPTIDE; PEPTIDE M; POTASSIUM CHANNEL BLOCKING AGENT; PSI CONOTOXIN; UNCLASSIFIED DRUG;

EID: 73749084685     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-009-0125-0     Document Type: Review
Times cited : (82)

References (68)
  • 1
    • 34447534651 scopus 로고    scopus 로고
    • Hyperhydroxylation: A new strategy for neuronal targeting by venomous marine molluscs
    • 1:CAS:528:DC%2BD28Xos1ymsb0%3D 17153339
    • A Franco K Pisarewicz C Moller D Mora GB Fields F Mari 2006 Hyperhydroxylation: a new strategy for neuronal targeting by venomous marine molluscs Prog Mol Subcell Biol 43 83 103 1:CAS:528:DC%2BD28Xos1ymsb0%3D 17153339
    • (2006) Prog Mol Subcell Biol , vol.43 , pp. 83-103
    • Franco, A.1    Pisarewicz, K.2    Moller, C.3    Mora, D.4    Fields, G.B.5    Mari, F.6
  • 2
    • 0001021863 scopus 로고
    • Conus peptides as chemical probes for receptors and ion channels
    • 10.1021/cr00021a013 1:CAS:528:DyaK3sXkvFKjur4%3D
    • RA Myers LJ Cruz JE Rivier BM Olivera 1993 Conus peptides as chemical probes for receptors and ion channels Chem Rev 93 5 1923 1936 10.1021/cr00021a013 1:CAS:528:DyaK3sXkvFKjur4%3D
    • (1993) Chem Rev , vol.93 , Issue.5 , pp. 1923-1936
    • Myers, R.A.1    Cruz, L.J.2    Rivier, J.E.3    Olivera, B.M.4
  • 3
    • 0032739544 scopus 로고    scopus 로고
    • Snail spears and scimitars: A character analysis of Conus radular teeth
    • 10.1093/mollus/65.4.461
    • AJ Kohn M Nishi B Pernet 1999 Snail spears and scimitars: a character analysis of Conus radular teeth J Mollus Stud 65 461 481 10.1093/mollus/65.4.461
    • (1999) J Mollus Stud , vol.65 , pp. 461-481
    • Kohn, A.J.1    Nishi, M.2    Pernet, B.3
  • 4
    • 40149108204 scopus 로고    scopus 로고
    • Three-dimensional structure of conotoxin tx3a: An m-1 branch peptide of the M-superfamily
    • DOI 10.1021/bi702388b
    • OM McDougal MW Turner AJ Ormond CD Poulter 2008 Three-dimensional structure of conotoxin tx3a: an m-1 branch peptide of the M-superfamily Biochemistry 47 2826 2832 10.1021/bi702388b 1:CAS:528:DC%2BD1cXptlyltg%3D%3D 18205318 (Pubitemid 351328833)
    • (2008) Biochemistry , vol.47 , Issue.9 , pp. 2826-2832
    • McDougal, O.M.1    Turner, M.W.2    Ormond, A.J.3    Poulter, C.D.4
  • 5
    • 0035239229 scopus 로고    scopus 로고
    • Conotoxins, in retrospect
    • 10.1016/S0041-0101(00)00157-4 1:CAS:528:DC%2BD3cXmsFKju7c%3D 10936619
    • BM Olivera LJ Cruz 2001 Conotoxins, in retrospect Toxicon 39 7 14 10.1016/S0041-0101(00)00157-4 1:CAS:528:DC%2BD3cXmsFKju7c%3D 10936619
    • (2001) Toxicon , vol.39 , pp. 7-14
    • Olivera, B.M.1    Cruz, L.J.2
  • 6
    • 0000748434 scopus 로고
    • Piscivorous gastropods of the genus Conus
    • 10.1073/pnas.42.3.168 1:STN:280:DC%2BD28zitFSlsQ%3D%3D 16589843
    • AJ Kohn 1956 Piscivorous gastropods of the genus Conus Proc Natl Acad Sci USA 42 168 171 10.1073/pnas.42.3.168 1:STN:280:DC%2BD28zitFSlsQ%3D%3D 16589843
    • (1956) Proc Natl Acad Sci USA , vol.42 , pp. 168-171
    • Kohn, A.J.1
  • 7
    • 0017567302 scopus 로고    scopus 로고
    • Characterization of the neurotoxic constituents of Conus geographus (L) venom
    • 10.1016/0024-3205(77)90156-4
    • I Spence D Gillessen RP Gregson RJ Quinn 1997 Characterization of the neurotoxic constituents of Conus geographus (L) venom Life Sci 21 1759 1770 10.1016/0024-3205(77)90156-4
    • (1997) Life Sci , vol.21 , pp. 1759-1770
    • Spence, I.1    Gillessen, D.2    Gregson, R.P.3    Quinn, R.J.4
  • 8
    • 0019844909 scopus 로고
    • A toxin from Conus geographus venom which acts on the vertebrate central nervous system
    • 10.1016/0041-0101(81)90106-9 1:CAS:528:DyaL38XivFKksw%3D%3D 6895426
    • C Clark BM Olivera LJ Cruz 1981 A toxin from Conus geographus venom which acts on the vertebrate central nervous system Toxicon 19 691 699 10.1016/0041-0101(81)90106-9 1:CAS:528:DyaL38XivFKksw%3D%3D 6895426
    • (1981) Toxicon , vol.19 , pp. 691-699
    • Clark, C.1    Olivera, B.M.2    Cruz, L.J.3
  • 9
    • 33645395545 scopus 로고    scopus 로고
    • A novel M-superfamily conotoxin with a unique motif from Conus vexillum
    • 10.1016/j.peptides.2005.08.004 1:CAS:528:DC%2BD28XjtFWru7s%3D 16181706
    • H Jiang CZ Wang CQ Xu CX Fan XD Dai JS Chen CW Chi 2006 A novel M-superfamily conotoxin with a unique motif from Conus vexillum Peptides 27 682 689 10.1016/j.peptides.2005.08.004 1:CAS:528:DC%2BD28XjtFWru7s%3D 16181706
    • (2006) Peptides , vol.27 , pp. 682-689
    • Jiang, H.1    Wang, C.Z.2    Xu, C.Q.3    Fan, C.X.4    Dai, X.D.5    Chen, J.S.6    Chi, C.W.7
  • 10
    • 0030729069 scopus 로고    scopus 로고
    • Conus venom peptides, receptor and ion channel targets and drug design: 50 million years of neuropharmacology
    • 1:CAS:528:DyaK2sXntFylu7c%3D 9362055
    • BM Olivera 1997 Conus venom peptides, receptor and ion channel targets and drug design: 50 million years of neuropharmacology Mol Biol Cell 8 2101 2109 1:CAS:528:DyaK2sXntFylu7c%3D 9362055
    • (1997) Mol Biol Cell , vol.8 , pp. 2101-2109
    • Olivera, B.M.1
  • 11
    • 33751049816 scopus 로고    scopus 로고
    • Conotoxins down under
    • DOI 10.1016/j.toxicon.2006.07.022, PII S0041010106002455
    • RS Norton BM Olivera 2006 Conotoxins down under Toxicon 48 780 798 10.1016/j.toxicon.2006.07.022 1:CAS:528:DC%2BD28Xht1WnsLbL 16952384 (Pubitemid 44755394)
    • (2006) Toxicon , vol.48 , Issue.7 , pp. 780-798
    • Norton, R.S.1    Olivera, B.M.2
  • 12
    • 57749115799 scopus 로고    scopus 로고
    • Pruning nature: Biodiversity-derived discovery of novel sodium channel blocking conotoxins from Conus bullatus
    • 10.1016/j.toxicon.2008.10.017 1:CAS:528:DC%2BD1cXhsFCjsL%2FJ 18950653
    • M Holford MM Zhang KH Gowd L Azam BR Green M Watkins JP Ownby D Yoshikami G Bulaj BM Olivera 2009 Pruning nature: biodiversity-derived discovery of novel sodium channel blocking conotoxins from Conus bullatus Toxicon 53 90 98 10.1016/j.toxicon.2008.10.017 1:CAS:528:DC%2BD1cXhsFCjsL%2FJ 18950653
    • (2009) Toxicon , vol.53 , pp. 90-98
    • Holford, M.1    Zhang, M.M.2    Gowd, K.H.3    Azam, L.4    Green, B.R.5    Watkins, M.6    Ownby, J.P.7    Yoshikami, D.8    Bulaj, G.9    Olivera, B.M.10
  • 14
    • 53749086169 scopus 로고    scopus 로고
    • Structure, dynamics, and selectivity of the sodium channel blocker (mu)-conotoxin SIIIA
    • 10.1021/bi801010u 1:CAS:528:DC%2BD1cXhtFaqtLnP 18798648
    • S Yao MM Zhang D Yoshikami L Azam BM Olivera G Bulaj RS Norton 2008 Structure, dynamics, and selectivity of the sodium channel blocker (mu)-conotoxin SIIIA Biochemistry 47 10940 10949 10.1021/bi801010u 1:CAS:528:DC%2BD1cXhtFaqtLnP 18798648
    • (2008) Biochemistry , vol.47 , pp. 10940-10949
    • Yao, S.1    Zhang, M.M.2    Yoshikami, D.3    Azam, L.4    Olivera, B.M.5    Bulaj, G.6    Norton, R.S.7
  • 15
    • 38849119207 scopus 로고    scopus 로고
    • ConoServer, a database for conopeptide sequences and structures
    • DOI 10.1093/bioinformatics/btm596
    • Q Kass JC Westermann R Halai CK Wang DJ Craik 2008 ConoServer, a database for conopeptide sequences and structures Bioinformatics 24 3 445 446 10.1093/bioinformatics/btm596 (Pubitemid 351189028)
    • (2008) Bioinformatics , vol.24 , Issue.3 , pp. 445-446
    • Kaas, Q.1    Westermann, J.-C.2    Halai, R.3    Wang, C.K.L.4    Craik, D.J.5
  • 16
    • 33846934770 scopus 로고    scopus 로고
    • Bio-business in brief: The case of conotoxins
    • 1:CAS:528:DC%2BD2sXitFSjs7k%3D
    • R Mehdiratta G Saberwal 2007 Bio-business in brief: the case of conotoxins Curr Sci 92 1 39 45 1:CAS:528:DC%2BD2sXitFSjs7k%3D
    • (2007) Curr Sci , vol.92 , Issue.1 , pp. 39-45
    • Mehdiratta, R.1    Saberwal, G.2
  • 18
    • 0642377359 scopus 로고    scopus 로고
    • Drugs from the sea: Conotoxins as drug leads for neuropathic pain and other neurological conditions
    • 10.2174/1389557033487746 1:CAS:528:DC%2BD3sXotlWjtr4%3D 14529519
    • D Alonso Z Khalil N Stakunanthan BG Livett 2003 Drugs from the sea: conotoxins as drug leads for neuropathic pain and other neurological conditions Mini Rev Med Chem 3 785 787 10.2174/1389557033487746 1:CAS:528: DC%2BD3sXotlWjtr4%3D 14529519
    • (2003) Mini Rev Med Chem , vol.3 , pp. 785-787
    • Alonso, D.1    Khalil, Z.2    Stakunanthan, N.3    Livett, B.G.4
  • 19
    • 0031796866 scopus 로고    scopus 로고
    • Pharmacotherapeutic potential of omega-conotoxin MVIIA (SNX-111), an N-type neuronal calcium channel blocker found in the venom of Conus magus
    • DOI 10.1016/S0041-0101(98)00158-5, PII S0041010198001585
    • SS Bowersox R Luther 1998 Pharmacotherapeutic potential of omega-conotoxin MVIIA (SNX-111), an N-type neuronal calcium channel blocker found in the venom of Conus magus Toxicon 36 11 1651 1658 10.1016/S0041-0101(98) 00158-5 1:CAS:528:DyaK1cXmsVWmsbo%3D 9792182 (Pubitemid 28511080)
    • (1998) Toxicon , vol.36 , Issue.11 , pp. 1651-1658
    • Bowersox, S.S.1    Luther, R.2
  • 21
    • 0033952153 scopus 로고    scopus 로고
    • Adverse effects associated with the intrathecal administration of ziconotide
    • DOI 10.1016/S0304-3959(99)00254-7, PII S0304395999002547
    • RD Penn JA Paice 2000 Adverse effects associated with the intrathecal administration of ziconotide Pain 85 1-2 291 296 10.1016/S0304-3959(99)00254-7 1:CAS:528:DC%2BD3cXht1OitLs%3D 10692631 (Pubitemid 30110772)
    • (2000) Pain , vol.85 , Issue.1-2 , pp. 291-296
    • Penn, R.D.1    Paice, J.A.2
  • 22
    • 0036185020 scopus 로고    scopus 로고
    • Intractable delirium associated with ziconotide successfully treated with electroconvulsive therapy
    • DOI 10.1176/appi.psy.43.1.63
    • T Levin G Petrides J Weiner S Saravay AS Multz S Bailine 2002 Intractable delirium associated with ziconotide successfully treated with electroconvulsive therapy Psychosomatics 43 63 66 10.1176/appi.psy.43.1.63 11927761 (Pubitemid 34214165)
    • (2002) Psychosomatics , vol.43 , Issue.1 , pp. 63-66
    • Levin, T.1    Petrides, G.2    Weiner, J.3    Saravay, S.4    Multz, A.S.5    Bailine, S.6
  • 23
    • 35648932526 scopus 로고    scopus 로고
    • Nonclinical safety of ziconotide: An intrathecal analgesic of a new pharmaceutical class
    • DOI 10.1080/10915810701582970, PII 783449631
    • MJ Skov JC Beck AW de Kater GM Shopp 2007 Nonclinical safety of ziconotide: an intrathecal analgesic of a new pharmaceutical class Int J Toxicol 26 5 411 421 10.1080/10915810701582970 1:CAS:528:DC%2BD2sXht1WgsbzJ 17963128 (Pubitemid 350034888)
    • (2007) International Journal of Toxicology , vol.26 , Issue.5 , pp. 411-421
    • Skov, M.J.1    Beck, J.C.2    De Kater, A.W.3    Shopp, G.M.4
  • 25
    • 33750054370 scopus 로고    scopus 로고
    • Characterization of novel M-superfamily conotoxins with new disulfide linkage
    • DOI 10.1111/j.1742-4658.2006.05493.x
    • YH Han Q Wang H Jiang L Liu C Xiao DD Yuan XX Shao QY Dai JS Chemng CW Chi 2006 Characterization of novel M-superfamily conotoxins with new disulfide linkage FEBS J 273 4972 4982 10.1111/j.1742-4658.2006.05493.x 1:CAS:528:DC%2BD28Xht1Grt7%2FF 17042781 (Pubitemid 44583519)
    • (2006) FEBS Journal , vol.273 , Issue.21 , pp. 4972-4982
    • Han, Y.-H.1    Wang, Q.2    Jiang, H.3    Liu, L.4    Xiao, C.5    Yuan, D.-D.6    Shao, X.-X.7    Dai, Q.-Y.8    Cheng, J.-S.9    Chi, C.-W.10
  • 26
    • 34247565154 scopus 로고    scopus 로고
    • Solution structure of an M-1 conotoxin with a novel disulfide linkage
    • DOI 10.1111/j.1742-4658.2007.05795.x
    • WH Du YH Han FJ Huang J Li CW Chi WH Fang 2007 Solution structure of an M-1 conotoxin with a novel disulfide linkage FEBS J 274 2596 2602 10.1111/j.1742-4658.2007.05795.x 1:CAS:528:DC%2BD2sXmtFGltrs%3D 17437523 (Pubitemid 46669345)
    • (2007) FEBS Journal , vol.274 , Issue.10 , pp. 2596-2602
    • Du, W.-H.1    Han, Y.-H.2    Huang, F.-J.3    Li, J.4    Chi, C.-W.5    Fang, W.-H.6
  • 27
    • 0346463128 scopus 로고    scopus 로고
    • Three-Dimensional Structure of the Mini-M Conotoxin mr3a
    • DOI 10.1021/bi0353732
    • O McDougal CD Poulter 2004 Three-dimensional structure of the Mini-M conotoxin mr3a Biochemistry 43 425 429 10.1021/bi0353732 1:CAS:528: DC%2BD3sXpvFKhtrk%3D 14717596 (Pubitemid 38082564)
    • (2004) Biochemistry , vol.43 , Issue.2 , pp. 425-429
    • McDougal, O.M.1    Poulter, C.D.2
  • 28
    • 40649093511 scopus 로고    scopus 로고
    • Two different groups of signal sequence in M-superfamily conotoxins
    • 10.1016/j.toxicon.2007.12.007 1:CAS:528:DC%2BD1cXjtlSju7s%3D 18242657
    • Q Wang H Jiang YH Han DD Yuan CW Chi 2008 Two different groups of signal sequence in M-superfamily conotoxins Toxicon 51 813 822 10.1016/j.toxicon.2007. 12.007 1:CAS:528:DC%2BD1cXjtlSju7s%3D 18242657
    • (2008) Toxicon , vol.51 , pp. 813-822
    • Wang, Q.1    Jiang, H.2    Han, Y.H.3    Yuan, D.D.4    Chi, C.W.5
  • 32
    • 64349101308 scopus 로고    scopus 로고
    • Structure of the analgesic (mu)-conotoxin KIIA and effects on structure and function of disulfide deletion
    • 10.1021/bi801998a 1:CAS:528:DC%2BD1MXhtVaqtLs%3D 19170536
    • KK Khoo ZP Feng BJ Smith MM Zhang D Yoshikami BM Olivera G Bulaj RS Norton 2009 Structure of the analgesic (mu)-conotoxin KIIA and effects on structure and function of disulfide deletion Biochemistry 48 1210 1219 10.1021/bi801998a 1:CAS:528:DC%2BD1MXhtVaqtLs%3D 19170536
    • (2009) Biochemistry , vol.48 , pp. 1210-1219
    • Khoo, K.K.1    Feng, Z.P.2    Smith, B.J.3    Zhang, M.M.4    Yoshikami, D.5    Olivera, B.M.6    Bulaj, G.7    Norton, R.S.8
  • 33
    • 33645302360 scopus 로고    scopus 로고
    • Recent advances in Cys-loop receptor structure and function
    • 10.1038/nature04708 1:CAS:528:DC%2BD28Xis1OlsL0%3D 16554804
    • SM Sine AG Engel 2006 Recent advances in Cys-loop receptor structure and function Nature 440 448 455 10.1038/nature04708 1:CAS:528:DC%2BD28Xis1OlsL0%3D 16554804
    • (2006) Nature , vol.440 , pp. 448-455
    • Sine, S.M.1    Engel, A.G.2
  • 35
    • 0022359989 scopus 로고
    • Conus geagraphus Toxins that discriminate between neuronal and muscle sodium channels
    • 1:CAS:528:DyaL2MXlvFWitL0%3D 2410412
    • LJ Cruz WR Gray BM Olivera RD Zeikus L Kerr D Yoshikami E Moczydlowski 1985 Conus geagraphus Toxins that discriminate between neuronal and muscle sodium channels J Biol Chem 260 16 9280 9288 1:CAS:528:DyaL2MXlvFWitL0%3D 2410412
    • (1985) J Biol Chem , vol.260 , Issue.16 , pp. 9280-9288
    • Cruz, L.J.1    Gray, W.R.2    Olivera, B.M.3    Zeikus, R.D.4    Kerr, L.5    Yoshikami, D.6    Moczydlowski, E.7
  • 36
    • 35649001607 scopus 로고
    • A quantitative description of membrane current and its application to conduction and excitation in nerve
    • 1:STN:280:DyaG3s%2FhsFGjug%3D%3D
    • AL Hodgkin AF Huxley 1952 A quantitative description of membrane current and its application to conduction and excitation in nerve J Physiol (Lond) 117 500 544 1:STN:280:DyaG3s%2FhsFGjug%3D%3D
    • (1952) J Physiol (Lond) , vol.117 , pp. 500-544
    • Hodgkin, A.L.1    Huxley, A.F.2
  • 37
    • 0021330126 scopus 로고
    • The molecular basis of neuronal excitability
    • 10.1126/science.6320365
    • WA Catterall 1984 The molecular basis of neuronal excitability Science 233 653 661 10.1126/science.6320365
    • (1984) Science , vol.233 , pp. 653-661
    • Catterall, W.A.1
  • 38
    • 2942687339 scopus 로고    scopus 로고
    • Identification of a mammalian target of κM-conotoxin RIIIK
    • DOI 10.1016/j.toxicon.2003.12.010, PII S0041010104001370
    • M Ferber A Al-Sabi M Stocker BM Olivera H Terlau 2004 Identification of a mammalian target of κM-conotoxin RIIIK Toxicon 43 915 921 10.1016/j.toxicon.2003.12.010 1:CAS:528:DC%2BD2cXkvFynsbs%3D 15208025 (Pubitemid 38781027)
    • (2004) Toxicon , vol.43 , Issue.8 , pp. 915-921
    • Ferber, M.1    Al-Sabi, A.2    Stocker, M.3    Olivera, B.M.4    Terlau, H.5
  • 42
    • 38349039512 scopus 로고    scopus 로고
    • Characterization of a novel psi-conotoxin from Conus parius
    • 10.1016/j.toxicon.2007.07.009 1:CAS:528:DC%2BD1cXnvVeltw%3D%3D 18054976
    • AO Lluisma E Lopez-Vera G Bulaj M Watkins BM Olivera 2008 Characterization of a novel psi-conotoxin from Conus parius Toxicon 51 174 180 10.1016/j.toxicon.2007.07.009 1:CAS:528:DC%2BD1cXnvVeltw%3D%3D 18054976
    • (2008) Toxicon , vol.51 , pp. 174-180
    • Lluisma, A.O.1    Lopez-Vera, E.2    Bulaj, G.3    Watkins, M.4    Olivera, B.M.5
  • 43
    • 0038010721 scopus 로고    scopus 로고
    • Characterization and three-dimensional structure determination of ψ-conotoxin PIIIF, a novel noncompetitive antagonist of nicotinic acetylcholine receptors
    • DOI 10.1021/bi0272757
    • RM Van Wagoner RB Jacobsen BM Olivera CM Ireland 2003 Characterization and three-dimensional structure determination of psi-conotoxin PIIIF, a novel noncompetitive antagonist of nicotinic acetylcholine receptors Biochemistry 42 21 6353 6362 10.1021/bi0272757 12767216 (Pubitemid 36665809)
    • (2003) Biochemistry , vol.42 , Issue.21 , pp. 6353-6362
    • Van Wagoner, R.M.1    Jacobsen, R.B.2    Olivera, B.M.3    Ireland, C.M.4
  • 44
    • 0344972098 scopus 로고    scopus 로고
    • Three-dimensional solution structure of conotoxin ψ-PIIIE, an acetylcholine gated ion channel antagonist
    • DOI 10.1021/bi972186t
    • SS Mitchell KJ Shon MP Foster DR Davis BM Olivera CM Ireland 1998 Three-dimensional solution structure of conotoxin psi-PIIIE, and acetylcholine gated ion channel antagonist Biochemistry 37 5 1215 1220 10.1021/bi972186t 1:CAS:528:DyaK1cXjs1Kltg%3D%3D 9477946 (Pubitemid 28135707)
    • (1998) Biochemistry , vol.37 , Issue.5 , pp. 1215-1220
    • Mitchell, S.S.1    Shon, K.J.2    Foster, M.P.3    Davis, D.R.4    Olivera, B.M.5    Ireland, C.M.6
  • 45
    • 0038348783 scopus 로고    scopus 로고
    • An improved solution structure for ψ-conotoxin PIIIE
    • DOI 10.1021/bi027274e
    • RM Van Wagoner CM Ireland 2003 An improved solution structure for psi-conotoxin PIIIE Biochemistry 43 21 6347 6352 10.1021/bi027274e (Pubitemid 36665808)
    • (2003) Biochemistry , vol.42 , Issue.21 , pp. 6347-6352
    • Van Wagoner, R.M.1    Ireland, C.M.2
  • 46
    • 29944442294 scopus 로고    scopus 로고
    • A novel conotoxin from Conus striatus, μ-SIIIA, selectively blocking rat tetrodotoxin-resistant sodium channels
    • DOI 10.1016/j.toxicon.2005.10.008, PII S0041010105003648
    • C-Z Wang H Zhang H Jiung W Lu Z-Q Zhao C-W Chi 2006 A novel conotoxin from Conus striatus, mu-SIIIA, selectively blocking rat tetrodotoxin-resistant sodium channels Toxicon 47 122 132 10.1016/j.toxicon.2005.10.008 1:CAS:528:DC%2BD28Xht1OisA%3D%3D 16325217 (Pubitemid 43042403)
    • (2006) Toxicon , vol.47 , Issue.1 , pp. 122-132
    • Wang, C.-Z.1    Zhang, H.2    Jiang, H.3    Lu, W.4    Zhao, Z.-Q.5    Chi, C.-W.6
  • 47
    • 33847158419 scopus 로고    scopus 로고
    • Isolation and structure-activity of μ-conotoxin TIIIA, a potent inhibitor of tetrodotoxin-sensitive voltage-gated sodium channels
    • DOI 10.1124/mol.106.028225
    • RJ Lewis CI Schroeder J Ekberg KJ Nielson M Loughnan L Thomas DA Adams R Drinkwater DJ Adams PF Alewood 2007 Isolation and structure-activity of mu-conotoxin TIIIA, a potent inhibitor of tetrodotoxin-sensitive voltage-gated sodium channels Mol Pharmacol 71 676 685 10.1124/mol.106.028225 1:CAS:528:DC%2BD2sXis1aqtLk%3D 17142296 (Pubitemid 46294079)
    • (2007) Molecular Pharmacology , vol.71 , Issue.3 , pp. 676-685
    • Lewis, R.J.1    Schroeder, C.I.2    Ekberg, J.3    Nielsen, K.J.4    Loughnan, M.5    Thomas, L.6    Adams, D.A.7    Drinkwater, R.8    Adams, D.J.9    Alewood, P.F.10
  • 48
    • 29844438166 scopus 로고    scopus 로고
    • International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels
    • DOI 10.1124/pr.57.4.4
    • WA Catterall AL Goldin SG Waxman 2005 International union of pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels Pharmacol Rev 57 397 409 10.1124/pr.57.4.4 1:CAS:528:DC%2BD28XhtFWgu74%3D 16382098 (Pubitemid 43036431)
    • (2005) Pharmacological Reviews , vol.57 , Issue.4 , pp. 397-409
    • Catterall, W.A.1    Goldin, A.L.2    Waxman, S.G.3
  • 50
    • 0033994386 scopus 로고    scopus 로고
    • Distinction among neuronal subtypes of voltage-activated sodium channels by mu-conotoxin PIIIA
    • 1:CAS:528:DC%2BD3cXhtF2itbY%3D 10627583
    • P Safo T Rosenbaum A Shcherbatko DY Choi E Han JJ Toledo-Aral BM Olivera P Brehm G Mandel 2000 Distinction among neuronal subtypes of voltage-activated sodium channels by mu-conotoxin PIIIA J Neurosci 20 1 76 80 1:CAS:528: DC%2BD3cXhtF2itbY%3D 10627583
    • (2000) J Neurosci , vol.20 , Issue.1 , pp. 76-80
    • Safo, P.1    Rosenbaum, T.2    Shcherbatko, A.3    Choi, D.Y.4    Han, E.5    Toledo-Aral, J.J.6    Olivera, B.M.7    Brehm, P.8    Mandel, G.9
  • 52
    • 0035839122 scopus 로고    scopus 로고
    • Modification of Arg-13 of μ-conotoxin GIIIA with piperidinyl-Arg analogs and their relation to the inhibition of sodium channels
    • DOI 10.1016/S0014-5793(01)02714-4, PII S0014579301027144
    • M Nakamura Y Niwa Y Ishida T Kohno K Sato Y Oba H Nakumura 2001 Modification of Arg-13 of μ-conotoxin GIIIA with piperidinyl-Arg analogs and their relation to the inhibition of sodium channels FEBS Lett 503 107 110 10.1016/S0014-5793(01)02714-4 1:CAS:528:DC%2BD3MXmtFWitrw%3D 11513864 (Pubitemid 32769965)
    • (2001) FEBS Letters , vol.503 , Issue.1 , pp. 107-110
    • Nakamura, M.1    Niwa, Y.2    Ishida, Y.3    Kohno, T.4    Sato, K.5    Oba, Y.6    Nakamura, H.7
  • 53
    • 18544378146 scopus 로고    scopus 로고
    • Novel conotoxins from Conus striatus and Conus kinoshitai selectively block TTX-resistant sodium channels
    • DOI 10.1021/bi0473408
    • G Bulaj PJ West JE Garrett M Watkins M-M Zhan RS Norton BJ Smith D Yoshikami BM Olivera 2005 Novel conotoxins from Conus striatus and Conus kinoshitai selectively block TTX-resistant sodium channels Biochemistry 44 19 7259 7265 10.1021/bi0473408 1:CAS:528:DC%2BD2MXjtl2jsbo%3D 15882064 (Pubitemid 40656669)
    • (2005) Biochemistry , vol.44 , Issue.19 , pp. 7259-7265
    • Bulaj, G.1    West, P.J.2    Garrett, J.E.3    Marsh, M.4    Zhang, M.-M.5    Norton, R.S.6    Smith, B.J.7    Yoshikami, D.8    Olivera, B.M.9
  • 55
    • 38549110472 scopus 로고    scopus 로고
    • Voltage-dependent Nav1.7 sodium channels: Multiple roles in adrenal chromaffin cells and peripheral nervous system
    • 1:CAS:528:DC%2BD1cXitFagsrY%3D
    • A Wada E Wanke F Gullo E Schiavon 2008 Voltage-dependent Nav1.7 sodium channels: multiple roles in adrenal chromaffin cells and peripheral nervous system Acta Physiol 192 221 231 1:CAS:528:DC%2BD1cXitFagsrY%3D
    • (2008) Acta Physiol , vol.192 , pp. 221-231
    • Wada, A.1    Wanke, E.2    Gullo, F.3    Schiavon, E.4
  • 56
    • 0034327493 scopus 로고    scopus 로고
    • Voltage-gated sodium channels as therapeutic targets
    • DOI 10.1016/S1359-6446(00)01570-1, PII S1359644600015701
    • JJ Clare SN Tate M Nobbs MA Romanos 2000 Voltage-gated sodium channels as therapeutic targets Drug Discov Today 5 506 520 10.1016/S1359-6446(00)01570-1 1:CAS:528:DC%2BD3cXotVKqtL0%3D 11084387 (Pubitemid 30838593)
    • (2000) Drug Discovery Today , vol.5 , Issue.11 , pp. 506-520
    • Clare, J.J.1    Tate, S.N.2    Nobbs, M.3    Romanos, M.A.4
  • 57
    • 52049126211 scopus 로고    scopus 로고
    • Neuronally mu-conotoxins from Conus striatus utilize an alpha-helical motif to target mammalian sodium channels
    • 10.1074/jbc.M802852200 1:CAS:528:DC%2BD1cXovFWrsb0%3D 18522941
    • CI Schroeder J Ekberg KJ Nielsen D Adams ML Loughnan L Thomas DJ Adams PF Alewood RJ Lewis 2008 Neuronally mu-conotoxins from Conus striatus utilize an alpha-helical motif to target mammalian sodium channels J Biol Chem 283 21621 21628 10.1074/jbc.M802852200 1:CAS:528:DC%2BD1cXovFWrsb0%3D 18522941
    • (2008) J Biol Chem , vol.283 , pp. 21621-21628
    • Schroeder, C.I.1    Ekberg, J.2    Nielsen, K.J.3    Adams, D.4    Loughnan, M.L.5    Thomas, L.6    Adams, D.J.7    Alewood, P.F.8    Lewis, R.J.9
  • 58
    • 23844559200 scopus 로고    scopus 로고
    • Sodium channel blockers in neuropathic pain
    • DOI 10.2174/1381612054865028
    • E Kalso 2005 Sodium channel blockers in neuropathic pain Curr Pharm Des 11 3005 3011 10.2174/1381612054865028 1:CAS:528:DC%2BD2MXotFaisL0%3D 16178759 (Pubitemid 41149937)
    • (2005) Current Pharmaceutical Design , vol.11 , Issue.23 , pp. 3005-3011
    • Kalso, E.1
  • 59
    • 4644357372 scopus 로고    scopus 로고
    • Voltage-gated sodium channels and pain pathways
    • DOI 10.1002/neu.20094
    • JN Wood JP Boorman K Okuse MD Baker 2004 Voltage-gated sodium channels and pain pathways J Neurobiol 61 55 71 10.1002/neu.20094 1:CAS:528: DC%2BD2cXovVajtrw%3D 15362153 (Pubitemid 39287770)
    • (2004) Journal of Neurobiology , vol.61 , Issue.1 , pp. 55-71
    • Wood, J.N.1    Boorman, J.P.2    Okuse, K.3    Baker, M.D.4
  • 61
    • 0030016085 scopus 로고    scopus 로고
    • Three-dimensional solution structure of μ-conotoxin GIIIB, a specific blocker of skeletal muscle sodium channels
    • DOI 10.1021/bi960073o
    • JM Hill PF Alewood DJ Craik 1996 Three-dimensional solution structure of μ-conotoxin GIIIB, a specific blocker of skeletal muscle sodium channels Biochemistry 35 8824 8835 10.1021/bi960073o 1:CAS:528:DyaK28XjsF2ku7w%3D 8688418 (Pubitemid 26243723)
    • (1996) Biochemistry , vol.35 , Issue.27 , pp. 8824-8835
    • Hill, J.M.1    Alewood, P.F.2    Craik, D.J.3
  • 62
    • 54849440134 scopus 로고    scopus 로고
    • NMR-based mapping of disulfide bridges in cysteine-rich peptides: Application to the mu-conotoxin SxIIIA
    • 10.1021/ja804303p 1:CAS:528:DC%2BD1cXht1Sjt7bK 18831583
    • A Walewska JJ Skalicky DR Davis M-M Zhang E Lopez-Vera M Watkins TS Han D Yoshikami BM Olivera G Bulaj 2008 NMR-based mapping of disulfide bridges in cysteine-rich peptides: application to the mu-conotoxin SxIIIA J Am Chem Soc 130 43 14280 14286 10.1021/ja804303p 1:CAS:528:DC%2BD1cXht1Sjt7bK 18831583
    • (2008) J Am Chem Soc , vol.130 , Issue.43 , pp. 14280-14286
    • Walewska, A.1    Skalicky, J.J.2    Davis, D.R.3    Zhang, M.-M.4    Lopez-Vera, E.5    Watkins, M.6    Han, T.S.7    Yoshikami, D.8    Olivera, B.M.9    Bulaj, G.10
  • 64
    • 0037168454 scopus 로고    scopus 로고
    • μ-conotoxin smIIIA, a potent inhibitor of tetrodotoxin-resistant sodium channels in amphibian sympathetic and sensory neurons
    • DOI 10.1021/bi0265628
    • PJ West G Bulaj JE Garrett BM Olivera D Yoshikami 2002 μ-Conotoxin SmIIIA, a potent inhibitor of tetrodotoxin-resistant sodium channels in amphibian sympathetic and sensory neurons Biochemistry 41 51 15388 15393 10.1021/bi0265628 1:CAS:528:DC%2BD38XovVeqsbw%3D 12484778 (Pubitemid 36008149)
    • (2002) Biochemistry , vol.41 , Issue.51 , pp. 15388-15393
    • West, P.J.1    Bulaj, G.2    Garrett, J.E.3    Olivera, B.M.4    Yoshikami, D.5
  • 65
    • 0033694833 scopus 로고    scopus 로고
    • From ionic currents to molecular mechanisms: The structure and function of voltage-gated sodium channels
    • 10.1016/S0896-6273(00)81133-2
    • WA Catteral 2000 From ionic currents to molecular mechanisms: the structure and function of voltage-gated sodium channels Neuron 26 13 25 10.1016/S0896-6273(00)81133-2
    • (2000) Neuron , vol.26 , pp. 13-25
    • Catteral, W.A.1
  • 66
    • 0345306633 scopus 로고    scopus 로고
    • Structural Basis for Tetrodotoxin-resistant Sodium Channel Binding by μ-Conotoxin SmIIIA
    • DOI 10.1074/jbc.M309222200
    • DW Keizer PJ West EF Lee D Yoshikami BM Olivera G Bulaj RS Norton 2003 Structural basis for tetrodotoxin-resistant sodium channel binding by μ-conotoxin SmIIIA J Biol Chem 278 47 46805 46813 10.1074/jbc.M309222200 1:CAS:528:DC%2BD3sXovFKksLo%3D 12970353 (Pubitemid 37452260)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.47 , pp. 46805-46813
    • Keizer, D.W.1    West, P.J.2    Lee, E.F.3    Yoshikami, D.4    Olivera, B.M.5    Bulaj, G.6    Norton, R.S.7
  • 67
    • 0346614200 scopus 로고
    • Discrimination of muscle and neuronal Na-channel subtypes by binding competition between saxitoxin and p-conotoxins
    • 10.1073/pnas.83.14.5321 1:CAS:528:DyaL28XltFSlurg%3D 2425365
    • E Moczydlowski BM Olivera WR Gray GR Strichartz 1986 Discrimination of muscle and neuronal Na-channel subtypes by binding competition between saxitoxin and p-conotoxins Proc Natl Acad Sci USA 83 5321 5325 10.1073/pnas.83.14.5321 1:CAS:528:DyaL28XltFSlurg%3D 2425365
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 5321-5325
    • Moczydlowski, E.1    Olivera, B.M.2    Gray, W.R.3    Strichartz, G.R.4


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