QSAR study of malonyl-CoA decarboxylase inhibitors using GA-MLR and a new strategy of consensus modeling

Journal of Computational Chemistry

Volumn 29, Issue 16, 2008, Pages 2636-2647

  Li, Jiazhong ^a   Lei, Bei ^a   Liu, Huanxiang ^a   Li, Shuyan ^a   Yao, Xiaojun ^a   Liu, Mancang ^a   Gramatica, Paola ^b  

^a LANZHOU UNIVERSITY   (China)

^b UNIVERSITY OF INSUBRIA   (Italy)

Author keywords

Average consensus model; Genetic algorithm; Malonyl coenzyme a decarboxylase; Q2 guided model selection; Sell organizing map; Weighted consensus model

Indexed keywords

GENETIC ALGORITHMS; HAMMING DISTANCE; NEURAL NETWORKS; POPULATION STATISTICS; STATISTICAL TESTS; SULFUR COMPOUNDS;

AVERAGE CONSENSUS MODEL; MALONYL COENZYME A DECARBOXYLASE; Q2 GUIDED MODEL SELECTION; SELL-ORGANIZING MAP; WEIGHTED CONSENSUS MODEL;

CONFORMAL MAPPING;

CARBOXYLYASE; ENZYME INHIBITOR; MALONYL COENZYME A DECARBOXYLASE; MALONYL-COA DECARBOXYLASE;

ALGORITHM; ARTICLE; ARTIFICIAL NEURAL NETWORK; CHEMISTRY; DRUG ANTAGONISM; QUANTITATIVE STRUCTURE ACTIVITY RELATION; STATISTICAL MODEL;

ALGORITHMS; CARBOXY-LYASES; ENZYME INHIBITORS; LINEAR MODELS; NEURAL NETWORKS (COMPUTER); QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 56949090293     PISSN: 01928651     EISSN: 1096987X     Source Type: Journal    
DOI: 10.1002/jcc.21002     Document Type: Article

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