Synonymous codon changes in the oncogenes of the cottontail rabbit papillomavirus lead to increased oncogenicity and immunogenicity of the virus

Virology

Volumn 438, Issue 2, 2013, Pages 70-83

  Cladel, Nancy M ^a,b   Budgeon, Lynn R ^a,b   Hu, Jiafen ^a,b   Balogh, Karla K ^a,b   Christensen, Neil D ^a,b  

^a PENN STATE CANCER INSTITUTE   (United States)

^b PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

Cancer; Codon usage; CRPV; E6; E7; Immunogenicity; In vivo model; Papillomavirus; Synonymous codons

Indexed keywords

HISTONE H3; MESSENGER RNA; MINICHROMOSOME MAINTENANCE PROTEIN 7; PHOSPHOHISTONE H3; PROTEIN E6; PROTEIN E7; TRANSFER RNA; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; CANCER DIAGNOSIS; CARCINOGENICITY; CODON; CONTROLLED STUDY; COPY NUMBER VARIATION; COTTONTAIL RABBIT PAPILLOMAVIRUS; DNA EXTRACTION; DNA SEQUENCE; DYSPLASIA; EARLY CANCER; GENETIC VARIABILITY; HISTOPATHOLOGY; IMMUNOGENICITY; IMMUNOSURVEILLANCE; NONHUMAN; NUCLEOTIDE SEQUENCE; ONCOGENE; PHENOTYPIC VARIATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RABBIT; RNA STABILITY; RNA STRUCTURE; STUNTING; SYNONYMOUS CODON; VIRUS GENOME;

AMINO ACID SEQUENCE; ANIMALS; CODON; COTTONTAIL RABBIT PAPILLOMAVIRUS; GENES, VIRAL; MUTATION; ONCOGENE PROTEINS, VIRAL; ONCOGENES; PAPILLOMA; PAPILLOMAVIRUS INFECTIONS; RABBITS;

ANIMALIA; COTTONTAIL RABBIT PAPILLOMAVIRUS; MAMMALIA; PAPILLOMAVIRIDAE;

EID: 84875257951     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2013.01.005     Document Type: Article

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