Succinate increases neuronal post-synaptic excitatory potentials in vitro and induces convulsive behavior through N-methyl-D-aspartate-mediated mechanisms

Neuroscience

Volumn 125, Issue 4, 2004, Pages 965-971

  Roehrs, C ^a   Garrido Sanabria, E R ^b,c   Da Silva, A C ^b   Faria, L C ^b   Sinhorin, V D G ^a   Marques, R H ^b   Priel, M R ^b   Rubin, M A ^a   Cavalheiro, E A ^b   Mello, C F ^a  

^a FEDERAL UNIVERSITY OF SANTA MARIA   (Brazil)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^c UNIVERSITY OF TEXAS AT BROWNSVILLE   (United States)

Author keywords

ACSF; analysis of variance; ANOVA; AP5; artificial cerebrospinal fluid; CNQX; convulsion; D 2 amino 5 phosphonovaleric acid; field excitatory post synaptic potentials; malonic acidemia; methylmalonic acidemia; succinate; succinate dehydrogenase

Indexed keywords

2 AMINO 5 PHOSPHONOVALERIC ACID; DIZOCILPINE; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; SUCCINATE DEHYDROGENASE; SUCCINIC ACID;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CONTROLLED STUDY; CONVULSION; DOSE RESPONSE; DRUG EFFECT; EXCITATORY POSTSYNAPTIC POTENTIAL; HIPPOCAMPUS; IN VITRO STUDY; MALE; MOUSE; NERVE CELL MEMBRANE POTENTIAL; NONHUMAN; PRIORITY JOURNAL; RAT; SEIZURE;

ANIMALS; DIZOCILPINE MALEATE; DOSE-RESPONSE RELATIONSHIP, DRUG; EXCITATORY AMINO ACID ANTAGONISTS; EXCITATORY POSTSYNAPTIC POTENTIALS; HIPPOCAMPUS; INJECTIONS, INTRAVENTRICULAR; MALE; MICE; NEURONS; NEUROPROTECTIVE AGENTS; RATS; RECEPTORS, N-METHYL-D-ASPARTATE; SEIZURES; SUCCINIC ACID;

EID: 11144354018     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2004.01.058     Document Type: Article

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