메뉴 건너뛰기




Volumn 45, Issue 1, 2012, Pages 165-176

Altered expression of brain monocarboxylate transporter 1 in models of temporal lobe epilepsy

Author keywords

Animal models; Blood brain barrier; Glutamine synthetase; Hippocampal sclerosis; Ketogenic diet; Ketone bodies

Indexed keywords

GLUTAMATE AMMONIA LIGASE; KETONE BODY; METHIONINE SULFOXIMINE; MONOCARBOXYLATE TRANSPORTER 1;

EID: 81955167995     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2011.08.001     Document Type: Article
Times cited : (42)

References (60)
  • 1
    • 0013895501 scopus 로고
    • Entorhinal activation of dentate granule cells
    • Andersen P., et al. Entorhinal activation of dentate granule cells. Acta Physiol. Scand. 1966, 66:448-460.
    • (1966) Acta Physiol. Scand. , vol.66 , pp. 448-460
    • Andersen, P.1
  • 2
    • 2342516133 scopus 로고    scopus 로고
    • Expression and cellular distribution of multidrug resistance-related proteins in the hippocampus of patients with mesial temporal lobe epilepsy
    • Aronica E., et al. Expression and cellular distribution of multidrug resistance-related proteins in the hippocampus of patients with mesial temporal lobe epilepsy. Epilepsia 2004, 45:441-451.
    • (2004) Epilepsia , vol.45 , pp. 441-451
    • Aronica, E.1
  • 3
    • 0021921141 scopus 로고
    • Limbic seizure and brain damage produced by kainic acid: mechanisms and relevance to human temporal lobe epilepsy
    • Ben-Ari Y. Limbic seizure and brain damage produced by kainic acid: mechanisms and relevance to human temporal lobe epilepsy. Neuroscience 1985, 14:375-403.
    • (1985) Neuroscience , vol.14 , pp. 375-403
    • Ben-Ari, Y.1
  • 4
    • 33846910806 scopus 로고    scopus 로고
    • Is lactate food for neurons? Comparison of monocarboxylate transporter subtypes in brain and muscle
    • Bergersen L.H. Is lactate food for neurons? Comparison of monocarboxylate transporter subtypes in brain and muscle. Neuroscience 2007, 145:11-19.
    • (2007) Neuroscience , vol.145 , pp. 11-19
    • Bergersen, L.H.1
  • 5
    • 0344527986 scopus 로고    scopus 로고
    • Cellular and subcellular expression of monocarboxylate transporters in the pigment epithelium and retina of the rat
    • Bergersen L., et al. Cellular and subcellular expression of monocarboxylate transporters in the pigment epithelium and retina of the rat. Neuroscience 1999, 90:319-331.
    • (1999) Neuroscience , vol.90 , pp. 319-331
    • Bergersen, L.1
  • 6
    • 33644844119 scopus 로고    scopus 로고
    • Cross-reinnervation changes the expression patterns of the monocarboxylate transporters 1 and 4: an experimental study in slow and fast rat skeletal muscle
    • Bergersen L.H., et al. Cross-reinnervation changes the expression patterns of the monocarboxylate transporters 1 and 4: an experimental study in slow and fast rat skeletal muscle. Neuroscience 2006, 138:1105-1113.
    • (2006) Neuroscience , vol.138 , pp. 1105-1113
    • Bergersen, L.H.1
  • 7
    • 0031398952 scopus 로고    scopus 로고
    • Design and construction of a long-term continuous video-EEG monitoring unit for simultaneous recording of multiple small animals
    • Bertram E.H., et al. Design and construction of a long-term continuous video-EEG monitoring unit for simultaneous recording of multiple small animals. Brain Res. Brain Res. Protoc. 1997, 1997:85-97.
    • (1997) Brain Res. Brain Res. Protoc. , vol.1997 , pp. 85-97
    • Bertram, E.H.1
  • 8
    • 55349119933 scopus 로고    scopus 로고
    • Energy metabolism as part of the anticonvulsant mechanism of the ketogenic diet
    • Bough K. Energy metabolism as part of the anticonvulsant mechanism of the ketogenic diet. Epilepsia 2008, 49(Suppl 8):91-93.
    • (2008) Epilepsia , vol.49 , Issue.SUPPL. 8 , pp. 91-93
    • Bough, K.1
  • 9
    • 53149145699 scopus 로고    scopus 로고
    • Minimal latency to hippocampal epileptogenesis and clinical epilepsy after perforant pathway stimulation-induced status epilepticus in awake rats
    • Bumanglag A.V., Sloviter R.S. Minimal latency to hippocampal epileptogenesis and clinical epilepsy after perforant pathway stimulation-induced status epilepticus in awake rats. J. Comp. Neurol. 2008, 510:561-580.
    • (2008) J. Comp. Neurol. , vol.510 , pp. 561-580
    • Bumanglag, A.V.1    Sloviter, R.S.2
  • 10
    • 34548459048 scopus 로고    scopus 로고
    • Ketogenic diet: electrophysiological effects on the normal human cortex
    • Cantello R., et al. Ketogenic diet: electrophysiological effects on the normal human cortex. Epilepsia 2007, 48:1756-1763.
    • (2007) Epilepsia , vol.48 , pp. 1756-1763
    • Cantello, R.1
  • 11
    • 72849142118 scopus 로고    scopus 로고
    • ABC transporters in drug-refractory epilepsy: limited clinical significance of pharmacogenetics?
    • Cascorbi I. ABC transporters in drug-refractory epilepsy: limited clinical significance of pharmacogenetics?. Clin. Pharmacol. Ther. 2010, 87:15-18.
    • (2010) Clin. Pharmacol. Ther. , vol.87 , pp. 15-18
    • Cascorbi, I.1
  • 12
    • 13144302856 scopus 로고    scopus 로고
    • Extracellular metabolites in the cortex and hippocampus of epileptic patients
    • Cavus I., et al. Extracellular metabolites in the cortex and hippocampus of epileptic patients. Ann. Neurol. 2005, 57:226-235.
    • (2005) Ann. Neurol. , vol.57 , pp. 226-235
    • Cavus, I.1
  • 13
    • 0020074781 scopus 로고
    • Developmental modulations of blood-brain barrier permeability as an indicator of changing nutritional requirements in the brain
    • Cornford E.M., et al. Developmental modulations of blood-brain barrier permeability as an indicator of changing nutritional requirements in the brain. Pediatr. Res. 1982, 16:324-328.
    • (1982) Pediatr. Res. , vol.16 , pp. 324-328
    • Cornford, E.M.1
  • 14
    • 0017177061 scopus 로고
    • Changes during development in transport processes of the blood-brain barrier
    • Cremer J.E., et al. Changes during development in transport processes of the blood-brain barrier. Biochim. Biophys. Acta 1976, 448:633-637.
    • (1976) Biochim. Biophys. Acta , vol.448 , pp. 633-637
    • Cremer, J.E.1
  • 15
  • 16
    • 57649171130 scopus 로고    scopus 로고
    • Imaging brain activation: simple pictures of complex biology
    • Dienel G.A., Cruz N.F. Imaging brain activation: simple pictures of complex biology. Ann. N. Y. Acad. Sci. 2008, 1147:139-170.
    • (2008) Ann. N. Y. Acad. Sci. , vol.1147 , pp. 139-170
    • Dienel, G.A.1    Cruz, N.F.2
  • 17
    • 0027262604 scopus 로고
    • Extracellular hippocampal glutamate and spontaneous seizure in the conscious human brain
    • During M.J., Spencer D.D. Extracellular hippocampal glutamate and spontaneous seizure in the conscious human brain. Lancet 1993, 341:1607-1610.
    • (1993) Lancet , vol.341 , pp. 1607-1610
    • During, M.J.1    Spencer, D.D.2
  • 18
    • 0028322158 scopus 로고
    • Direct measurement of extracellular lactate in the human hippocampus during spontaneous seizures
    • During M.J., et al. Direct measurement of extracellular lactate in the human hippocampus during spontaneous seizures. J. Neurochem. 1994, 62:2356-2361.
    • (1994) J. Neurochem. , vol.62 , pp. 2356-2361
    • During, M.J.1
  • 19
    • 12844282842 scopus 로고    scopus 로고
    • + homeostasis in the human epileptogenic hippocampus
    • + homeostasis in the human epileptogenic hippocampus. Proc. Natl. Acad. Sci. U. S. A. 2005, 102:1193-1198.
    • (2005) Proc. Natl. Acad. Sci. U. S. A. , vol.102 , pp. 1193-1198
    • Eid, T.1
  • 20
    • 49449111897 scopus 로고    scopus 로고
    • Recurrent seizures and brain pathology after inhibition of glutamine synthetase in the hippocampus in rats
    • Eid T., et al. Recurrent seizures and brain pathology after inhibition of glutamine synthetase in the hippocampus in rats. Brain 2008, 131:2061-2070.
    • (2008) Brain , vol.131 , pp. 2061-2070
    • Eid, T.1
  • 21
    • 52949115270 scopus 로고    scopus 로고
    • Transport of valproate at intestinal epithelial (Caco-2) and brain endothelial (RBE4) cells: mechanism and substrate specificity
    • Fischer W., et al. Transport of valproate at intestinal epithelial (Caco-2) and brain endothelial (RBE4) cells: mechanism and substrate specificity. Eur. J. Pharm. Biopharm. 2008, 70:486-492.
    • (2008) Eur. J. Pharm. Biopharm. , vol.70 , pp. 486-492
    • Fischer, W.1
  • 22
    • 0029009408 scopus 로고
    • Immunolocalization of the mercurial-insensitive water channel and glycerol intrinsic protein in epithelial cell plasma membranes
    • Frigeri A., et al. Immunolocalization of the mercurial-insensitive water channel and glycerol intrinsic protein in epithelial cell plasma membranes. Proc. Natl. Acad. Sci. U. S. A. 1995, 92:4328-4331.
    • (1995) Proc. Natl. Acad. Sci. U. S. A. , vol.92 , pp. 4328-4331
    • Frigeri, A.1
  • 23
    • 0030837750 scopus 로고    scopus 로고
    • Expression of monocarboxylate tranpsorter MCT1 by brain endothelium and glia in adult and suckling rats
    • Gerhart D.Z., et al. Expression of monocarboxylate tranpsorter MCT1 by brain endothelium and glia in adult and suckling rats. Am. J. Physiol. 1997, 273:207-213.
    • (1997) Am. J. Physiol. , vol.273 , pp. 207-213
    • Gerhart, D.Z.1
  • 24
    • 0002545867 scopus 로고
    • Mesial temporal sclerosis: historical background and an overview from a modern perspective
    • Raven Press, New York, H. Luders (Ed.)
    • Gloor P. Mesial temporal sclerosis: historical background and an overview from a modern perspective. Epilepsy Surgery 1991, 689-703. Raven Press, New York. H. Luders (Ed.).
    • (1991) Epilepsy Surgery , pp. 689-703
    • Gloor, P.1
  • 25
    • 0023760665 scopus 로고
    • The new stereological tools
    • 379-394 & 857-881
    • Gundersen H.J.G., et al. The new stereological tools. APMIS 1988, 96. 379-394 & 857-881.
    • (1988) APMIS , vol.96
    • Gundersen, H.J.G.1
  • 26
    • 21644443575 scopus 로고    scopus 로고
    • Hippocampal granule cell activity and c-Fos expression during spontaneous seizures in awake, chronically epileptic, pilocarpine-treated rats: implications for hippocampal epileptogenesis
    • Harvey B.D., Sloviter R.S. Hippocampal granule cell activity and c-Fos expression during spontaneous seizures in awake, chronically epileptic, pilocarpine-treated rats: implications for hippocampal epileptogenesis. J. Comp. Neurol. 2005, 488:442-463.
    • (2005) J. Comp. Neurol. , vol.488 , pp. 442-463
    • Harvey, B.D.1    Sloviter, R.S.2
  • 27
    • 0027152087 scopus 로고
    • Incidence of epilepsy and unprovoked seizures in Rochester, Minnesota: 1935-1984
    • Hauser W.A., et al. Incidence of epilepsy and unprovoked seizures in Rochester, Minnesota: 1935-1984. Epilepsia 1993, 34:453-468.
    • (1993) Epilepsia , vol.34 , pp. 453-468
    • Hauser, W.A.1
  • 28
    • 12244295472 scopus 로고    scopus 로고
    • Lactate transport and transporters: general principles and functional roles in brain cells
    • Hertz L., Dienel G.A. Lactate transport and transporters: general principles and functional roles in brain cells. J. Neurosci. Res. 2005, 79:11-18.
    • (2005) J. Neurosci. Res. , vol.79 , pp. 11-18
    • Hertz, L.1    Dienel, G.A.2
  • 29
    • 58249136154 scopus 로고    scopus 로고
    • Characterization of (14)C-acetate uptake in cultured rat astrocytes
    • Hosoi R., et al. Characterization of (14)C-acetate uptake in cultured rat astrocytes. Brain Res. 2009, 1253:69-73.
    • (2009) Brain Res. , vol.1253 , pp. 69-73
    • Hosoi, R.1
  • 30
    • 72649101944 scopus 로고    scopus 로고
    • 14C-acetate uptake in an epilepsy model rat brain induced by lithium-pilocarpine
    • 14C-acetate uptake in an epilepsy model rat brain induced by lithium-pilocarpine. Brain Res. 2010, 1311:158-165.
    • (2010) Brain Res. , vol.1311 , pp. 158-165
    • Hosoi, R.1
  • 31
    • 0019423594 scopus 로고
    • Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures
    • Hsu S., et al. Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures. J. Histochem. Cytochem. 1981, 29:577-580.
    • (1981) J. Histochem. Cytochem. , vol.29 , pp. 577-580
    • Hsu, S.1
  • 32
    • 0029115356 scopus 로고
    • CDNA cloning of MCT1, a monocarboxylate transporter from rat skeletal muscle
    • Jackson V.N., et al. cDNA cloning of MCT1, a monocarboxylate transporter from rat skeletal muscle. Biochim. Biophys. Acta 1995, 1238:193-196.
    • (1995) Biochim. Biophys. Acta , vol.1238 , pp. 193-196
    • Jackson, V.N.1
  • 33
    • 77957307251 scopus 로고    scopus 로고
    • Metabolic control of vesicular glutamate transport and release
    • Juge N., et al. Metabolic control of vesicular glutamate transport and release. Neuron 2010, 68:99-112.
    • (2010) Neuron , vol.68 , pp. 99-112
    • Juge, N.1
  • 34
    • 0025322779 scopus 로고
    • Acidic drug transport in vivo through the blood-brain barrier. A role of the transport carrier for monocarboxylic acids
    • Kang Y.S., et al. Acidic drug transport in vivo through the blood-brain barrier. A role of the transport carrier for monocarboxylic acids. J. Pharmacobiodyn. 1990, 13:158-163.
    • (1990) J. Pharmacobiodyn. , vol.13 , pp. 158-163
    • Kang, Y.S.1
  • 35
    • 0031719871 scopus 로고    scopus 로고
    • Monocarboxylate ransporter expression in mouse brain
    • Koehler-Stec E.M., et al. Monocarboxylate ransporter expression in mouse brain. Am. J. Physiol. 1998, 275:E516-E524.
    • (1998) Am. J. Physiol. , vol.275
    • Koehler-Stec, E.M.1
  • 36
    • 33644503533 scopus 로고    scopus 로고
    • Distribution and functional activity of P-glycoprotein and multidrug resistance-associated proteins in human brain microvascular endothelial cells in hippocampal sclerosis
    • Kubota H., et al. Distribution and functional activity of P-glycoprotein and multidrug resistance-associated proteins in human brain microvascular endothelial cells in hippocampal sclerosis. Epilepsy Res. 2006, 68:213-228.
    • (2006) Epilepsy Res. , vol.68 , pp. 213-228
    • Kubota, H.1
  • 37
    • 78650622142 scopus 로고    scopus 로고
    • Monocarboxylate transporter 1 is deficient on microvessels in the human epileptogenic hippocampus
    • Lauritzen F., et al. Monocarboxylate transporter 1 is deficient on microvessels in the human epileptogenic hippocampus. Neurobiol. Dis. 2011, 41:577-584.
    • (2011) Neurobiol. Dis. , vol.41 , pp. 577-584
    • Lauritzen, F.1
  • 38
    • 8844266903 scopus 로고    scopus 로고
    • Aquaporin-4 is increased in the sclerotic hippocampus in human temporal lobe epilepsy
    • Lee T.S., et al. Aquaporin-4 is increased in the sclerotic hippocampus in human temporal lobe epilepsy. Acta Neuropathol. (Berl) 2004, 108:493-502.
    • (2004) Acta Neuropathol. (Berl) , vol.108 , pp. 493-502
    • Lee, T.S.1
  • 39
    • 0033548527 scopus 로고    scopus 로고
    • Monocarboxylate transporter (MCT1) abundance in brains of suckling and adult rats: a quantitative electron microscopic immunogold study
    • Leino R.L., et al. Monocarboxylate transporter (MCT1) abundance in brains of suckling and adult rats: a quantitative electron microscopic immunogold study. Brain Res. Dev. Brain Res. 1999, 113:47-54.
    • (1999) Brain Res. Dev. Brain Res. , vol.113 , pp. 47-54
    • Leino, R.L.1
  • 40
    • 0035106634 scopus 로고    scopus 로고
    • Diet-induced ketosis increases monocarboxylate transporter (MCT1) levels in rat brain
    • Leino R.L., et al. Diet-induced ketosis increases monocarboxylate transporter (MCT1) levels in rat brain. Neurochem. Int. 2001, 38:519-527.
    • (2001) Neurochem. Int. , vol.38 , pp. 519-527
    • Leino, R.L.1
  • 41
    • 33847095107 scopus 로고    scopus 로고
    • Drug transporters in the epileptic brain
    • Loscher W. Drug transporters in the epileptic brain. Epilepsia 2007, 48(Suppl 1):8-13.
    • (2007) Epilepsia , vol.48 , Issue.SUPPL. 1 , pp. 8-13
    • Loscher, W.1
  • 42
    • 72849124491 scopus 로고    scopus 로고
    • Transporters in drug-refractory epilepsy: clinical significance
    • Marchi N., et al. Transporters in drug-refractory epilepsy: clinical significance. Clin. Pharmacol. Ther. 2010, 87:13-15.
    • (2010) Clin. Pharmacol. Ther. , vol.87 , pp. 13-15
    • Marchi, N.1
  • 43
    • 0018848558 scopus 로고
    • Kainic acid neurotoxicity toward the hippocampal formation: dependence on specific excitatory pathways
    • Nadler J., Cuthbertson G. Kainic acid neurotoxicity toward the hippocampal formation: dependence on specific excitatory pathways. Brain Res. 1980, 195:47-56.
    • (1980) Brain Res. , vol.195 , pp. 47-56
    • Nadler, J.1    Cuthbertson, G.2
  • 44
    • 0031022918 scopus 로고    scopus 로고
    • Specialized membrane domains for water transport in glial cells: high-resolution immunogold cytochemistry of aquaporin-4 in rat brain
    • Nielsen S., et al. Specialized membrane domains for water transport in glial cells: high-resolution immunogold cytochemistry of aquaporin-4 in rat brain. J. Neurosci. 1997, 17:171-180.
    • (1997) J. Neurosci. , vol.17 , pp. 171-180
    • Nielsen, S.1
  • 45
    • 0033142036 scopus 로고    scopus 로고
    • Ketosis and epilepsy: 31P spectroscopic imaging at 4.1T
    • Pan J.W., et al. Ketosis and epilepsy: 31P spectroscopic imaging at 4.1T. Epilepsia 1999, 40:703-707.
    • (1999) Epilepsia , vol.40 , pp. 703-707
    • Pan, J.W.1
  • 47
    • 0032584084 scopus 로고    scopus 로고
    • Expression of monocarboxylate transporter mRNAs in mouse brain: support for a distinct role of lactate as an energy substrate for the neonatal vs. adult brain
    • Pellerin L., et al. Expression of monocarboxylate transporter mRNAs in mouse brain: support for a distinct role of lactate as an energy substrate for the neonatal vs. adult brain. Proc. Natl. Acad. Sci. U. S. A. 1998, 95:3990-3995.
    • (1998) Proc. Natl. Acad. Sci. U. S. A. , vol.95 , pp. 3990-3995
    • Pellerin, L.1
  • 48
    • 0034721575 scopus 로고    scopus 로고
    • Cell-specific localization of monocarboxylate transporters, MCT1 and MCT2, in the adult mouse brain revealed by double immunohistochemical labeling and confocal microscopy
    • Pierre K., et al. Cell-specific localization of monocarboxylate transporters, MCT1 and MCT2, in the adult mouse brain revealed by double immunohistochemical labeling and confocal microscopy. Neuroscience 2000, 100:617-627.
    • (2000) Neuroscience , vol.100 , pp. 617-627
    • Pierre, K.1
  • 49
    • 0032518981 scopus 로고    scopus 로고
    • Cloning and sequencing of four new mammalian monocarboxylate transporter (MCT) homologues confirms the existence of a transporter family with an ancient past
    • Price N.T., et al. Cloning and sequencing of four new mammalian monocarboxylate transporter (MCT) homologues confirms the existence of a transporter family with an ancient past. Biochem. J. 1998, 329(Pt 2):321-328.
    • (1998) Biochem. J. , vol.329 , Issue.PART. 2 , pp. 321-328
    • Price, N.T.1
  • 50
    • 0015895746 scopus 로고
    • Rates of motor seizure development in rats subjected to electrical brain stimulation: strain and inter-stimulation interval effects
    • Racine R.J., et al. Rates of motor seizure development in rats subjected to electrical brain stimulation: strain and inter-stimulation interval effects. Electroencephalogr. Clin. Neurophysiol. 1973, 35:553-556.
    • (1973) Electroencephalogr. Clin. Neurophysiol. , vol.35 , pp. 553-556
    • Racine, R.J.1
  • 51
    • 57249094423 scopus 로고    scopus 로고
    • Hippocampal epileptogenesis in animal models of mesial temporal lobe epilepsy with hippocampal sclerosis: the importance of the "latent period" and other concepts
    • Sloviter R.S. Hippocampal epileptogenesis in animal models of mesial temporal lobe epilepsy with hippocampal sclerosis: the importance of the "latent period" and other concepts. Epilepsia 2008, 49(Suppl 9):85-92.
    • (2008) Epilepsia , vol.49 , Issue.SUPPL. 9 , pp. 85-92
    • Sloviter, R.S.1
  • 52
    • 0029813744 scopus 로고    scopus 로고
    • Basal expression and induction of glutamate decarboxylase and GABA in excitatory granule cells of the rat and monkey hippocampal dentate gyrus
    • Sloviter R.S., et al. Basal expression and induction of glutamate decarboxylase and GABA in excitatory granule cells of the rat and monkey hippocampal dentate gyrus. J. Comp. Neurol. 1996, 373:593-618.
    • (1996) J. Comp. Neurol. , vol.373 , pp. 593-618
    • Sloviter, R.S.1
  • 53
    • 35748958399 scopus 로고    scopus 로고
    • On the relevance of prolonged convulsive status epilepticus in animals to the etiology and neurobiology of human temporal lobe epilepsy
    • Sloviter R.S., et al. On the relevance of prolonged convulsive status epilepticus in animals to the etiology and neurobiology of human temporal lobe epilepsy. Epilepsia 2007, 48(Suppl 8):6-10.
    • (2007) Epilepsia , vol.48 , Issue.SUPPL. 8 , pp. 6-10
    • Sloviter, R.S.1
  • 54
    • 34250548773 scopus 로고
    • Erkrankung des Ammonshorns als aetiologisches Moment der Epilepsie
    • Sommer W. Erkrankung des Ammonshorns als aetiologisches Moment der Epilepsie. Arch. Psychiatr. Nervenkr. 1880, 10:631-675.
    • (1880) Arch. Psychiatr. Nervenkr. , vol.10 , pp. 631-675
    • Sommer, W.1
  • 55
    • 0036208029 scopus 로고    scopus 로고
    • Neural networks in human epilepsy: evidence of and implications for treatment
    • Spencer S.S. Neural networks in human epilepsy: evidence of and implications for treatment. Epilepsia 2002, 43:219-227.
    • (2002) Epilepsia , vol.43 , pp. 219-227
    • Spencer, S.S.1
  • 56
    • 0025989302 scopus 로고
    • Transport of monocarboxylic acids at the blood-brain barrier: studies with monolayers of primary cultured bovine brain capillary endothelial cells
    • Terasaki T., et al. Transport of monocarboxylic acids at the blood-brain barrier: studies with monolayers of primary cultured bovine brain capillary endothelial cells. J. Pharmacol. Exp. Ther. 1991, 258:932-937.
    • (1991) J. Pharmacol. Exp. Ther. , vol.258 , pp. 932-937
    • Terasaki, T.1
  • 57
    • 0020545095 scopus 로고
    • Limbic seizures produced by pilocarpine in rats: behavioural, electroencephalographic and neuropathological study
    • Turski W.A., et al. Limbic seizures produced by pilocarpine in rats: behavioural, electroencephalographic and neuropathological study. Behav. Brain Res. 1983, 9:315-335.
    • (1983) Behav. Brain Res. , vol.9 , pp. 315-335
    • Turski, W.A.1
  • 58
    • 0033962691 scopus 로고    scopus 로고
    • Carrier-mediated transport of valproic acid in BeWo cells, a human trophoblast cell line
    • Utoguchi N., Audus K.L. Carrier-mediated transport of valproic acid in BeWo cells, a human trophoblast cell line. Int. J. Pharm. 2000, 195:115-124.
    • (2000) Int. J. Pharm. , vol.195 , pp. 115-124
    • Utoguchi, N.1    Audus, K.L.2
  • 59
    • 71549141314 scopus 로고    scopus 로고
    • The development of recurrent seizures after continuous intrahippocampal infusion of methionine sulfoximine in rats: a video-intracranial electroencephalographic study
    • Wang Y., et al. The development of recurrent seizures after continuous intrahippocampal infusion of methionine sulfoximine in rats: a video-intracranial electroencephalographic study. Exp. Neurol. 2009, 220:293-302.
    • (2009) Exp. Neurol. , vol.220 , pp. 293-302
    • Wang, Y.1
  • 60
    • 1042265007 scopus 로고    scopus 로고
    • Ketogenic diet, brain glutamate metabolism and seizure control
    • Yudkoff M., et al. Ketogenic diet, brain glutamate metabolism and seizure control. Prostaglandins Leukot. Essent. Fatty Acids 2004, 70:277-285.
    • (2004) Prostaglandins Leukot. Essent. Fatty Acids , vol.70 , pp. 277-285
    • Yudkoff, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.