-
1
-
-
77957079503
-
What causes a broken heart-molecular insights into heart failure
-
Barry S.P., Townsend P.A. What causes a broken heart-molecular insights into heart failure. Int. Rev. Cell Mol. Biol. 2010, 284:113-179.
-
(2010)
Int. Rev. Cell Mol. Biol.
, vol.284
, pp. 113-179
-
-
Barry, S.P.1
Townsend, P.A.2
-
3
-
-
0037050022
-
The failing heart
-
Towbin J.A., Bowles N.E. The failing heart. Nature 2002, 415:227-233.
-
(2002)
Nature
, vol.415
, pp. 227-233
-
-
Towbin, J.A.1
Bowles, N.E.2
-
4
-
-
56849090830
-
Fibrosis: a living tissue and the infarcted heart
-
Weber K.T., Sun Y., Diez J. Fibrosis: a living tissue and the infarcted heart. J. Am. Coll. Cardiol. 2008, 52:2029-2031.
-
(2008)
J. Am. Coll. Cardiol.
, vol.52
, pp. 2029-2031
-
-
Weber, K.T.1
Sun, Y.2
Diez, J.3
-
5
-
-
37849026328
-
Molecular remodeling in human heart failure
-
Cappola T.P. Molecular remodeling in human heart failure. J. Am. Coll. Cardiol. 2008, 51:137-178.
-
(2008)
J. Am. Coll. Cardiol.
, vol.51
, pp. 137-178
-
-
Cappola, T.P.1
-
6
-
-
1842579393
-
Hypertrophy of the heart: a new therapeutic target?
-
Frey N., Katus H.A., Olson E.N., Hill J.A. Hypertrophy of the heart: a new therapeutic target?. Circulation 2004, 109:1580-1589.
-
(2004)
Circulation
, vol.109
, pp. 1580-1589
-
-
Frey, N.1
Katus, H.A.2
Olson, E.N.3
Hill, J.A.4
-
7
-
-
33947150568
-
A-kinase anchoring proteins take shape
-
Beene D.L., Scott J.D. A-kinase anchoring proteins take shape. Curr. Opin. Cell Biol. 2007, 19:192-198.
-
(2007)
Curr. Opin. Cell Biol.
, vol.19
, pp. 192-198
-
-
Beene, D.L.1
Scott, J.D.2
-
8
-
-
77953953091
-
Signal integration through blending, bolstering and bifurcating of intracellular information
-
Pawson C.T., Scott J.D. Signal integration through blending, bolstering and bifurcating of intracellular information. Nat. Struct. Mol. Biol. 2010, 17:653-658.
-
(2010)
Nat. Struct. Mol. Biol.
, vol.17
, pp. 653-658
-
-
Pawson, C.T.1
Scott, J.D.2
-
9
-
-
77950642292
-
Networking with AKAPs: context-dependent regulation of anchored enzymes
-
Welch E.J., Jones B.W., Scott J.D. Networking with AKAPs: context-dependent regulation of anchored enzymes. Mol. Interv. 2010, 10:86-97.
-
(2010)
Mol. Interv.
, vol.10
, pp. 86-97
-
-
Welch, E.J.1
Jones, B.W.2
Scott, J.D.3
-
11
-
-
33750480828
-
Molecular basis of AKAP specificity for PKA regulatory subunits
-
Gold M.G., Lygren B., Dokurno P., Hoshi N., McConnachie G., Tasken K., Carlson C.R., Scott J.D., Barford D. Molecular basis of AKAP specificity for PKA regulatory subunits. Mol. Cell 2006, 24:383-395.
-
(2006)
Mol. Cell
, vol.24
, pp. 383-395
-
-
Gold, M.G.1
Lygren, B.2
Dokurno, P.3
Hoshi, N.4
McConnachie, G.5
Tasken, K.6
Carlson, C.R.7
Scott, J.D.8
Barford, D.9
-
12
-
-
33750474414
-
A dynamic mechanism for AKAP binding to RII isoforms of cAMP-dependent protein kinase
-
Kinderman F.S., Kim C., von Daake S., Ma Y., Pham B.Q., Spraggon G., Xuong N.H., Jennings P.A., Taylor S.S. A dynamic mechanism for AKAP binding to RII isoforms of cAMP-dependent protein kinase. Mol. Cell 2006, 24:397-408.
-
(2006)
Mol. Cell
, vol.24
, pp. 397-408
-
-
Kinderman, F.S.1
Kim, C.2
von Daake, S.3
Ma, Y.4
Pham, B.Q.5
Spraggon, G.6
Xuong, N.H.7
Jennings, P.A.8
Taylor, S.S.9
-
13
-
-
77956151719
-
Mechanisms of protein kinase A anchoring
-
Skroblin P., Grossmann S., Schafer G., Rosenthal W., Klussmann E. Mechanisms of protein kinase A anchoring. Int. Rev. Cell Mol. Biol. 2010, 283:235-330.
-
(2010)
Int. Rev. Cell Mol. Biol.
, vol.283
, pp. 235-330
-
-
Skroblin, P.1
Grossmann, S.2
Schafer, G.3
Rosenthal, W.4
Klussmann, E.5
-
14
-
-
33750804385
-
Phosphorylation of serine 1928 in the distal C-terminal domain of cardiac CaV1.2 channels during beta1-adrenergic regulation
-
Hulme J.T., Westenbroek R.E., Scheuer T., Catterall W.A. Phosphorylation of serine 1928 in the distal C-terminal domain of cardiac CaV1.2 channels during beta1-adrenergic regulation. Proc. Natl. Acad. Sci. U. S. A. 2006, 103:16574-16579.
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 16574-16579
-
-
Hulme, J.T.1
Westenbroek, R.E.2
Scheuer, T.3
Catterall, W.A.4
-
15
-
-
0034640113
-
PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts
-
Marx S.O., Reiken S., Hisamatsu Y., Jayaraman T., Burkhoff D., Rosemblit N., Marks A.R. PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts. Cell 2000, 101:365-376.
-
(2000)
Cell
, vol.101
, pp. 365-376
-
-
Marx, S.O.1
Reiken, S.2
Hisamatsu, Y.3
Jayaraman, T.4
Burkhoff, D.5
Rosemblit, N.6
Marks, A.R.7
-
16
-
-
0036167330
-
Dual site phospholamban phosphorylation and its physiological relevance in the heart
-
Hagemann D., Xiao R.P. Dual site phospholamban phosphorylation and its physiological relevance in the heart. Trends Cardiovasc. Med. 2002, 12:51-56.
-
(2002)
Trends Cardiovasc. Med.
, vol.12
, pp. 51-56
-
-
Hagemann, D.1
Xiao, R.P.2
-
18
-
-
0035947749
-
Phosphorylation of troponin I by protein kinase A accelerates relaxation and crossbridge cycle kinetics in mouse ventricular muscle
-
Kentish J.C., McCloskey D.T., Layland J., Palmer S., Leiden J.M., Martin A.F., Solaro R.J. Phosphorylation of troponin I by protein kinase A accelerates relaxation and crossbridge cycle kinetics in mouse ventricular muscle. Circ. Res. 2001, 88:1059-1065.
-
(2001)
Circ. Res.
, vol.88
, pp. 1059-1065
-
-
Kentish, J.C.1
McCloskey, D.T.2
Layland, J.3
Palmer, S.4
Leiden, J.M.5
Martin, A.F.6
Solaro, R.J.7
-
19
-
-
34548356872
-
Differential roles of cardiac myosin-binding protein C and cardiac troponin I in the myofibrillar force responses to protein kinase A phosphorylation
-
Stelzer J.E., Patel J.R., Walker J.W., Moss R.L. Differential roles of cardiac myosin-binding protein C and cardiac troponin I in the myofibrillar force responses to protein kinase A phosphorylation. Circ. Res. 2007, 101:503-511.
-
(2007)
Circ. Res.
, vol.101
, pp. 503-511
-
-
Stelzer, J.E.1
Patel, J.R.2
Walker, J.W.3
Moss, R.L.4
-
20
-
-
0037127028
-
Requirement of a macromolecular signaling complex for beta adrenergic receptor modulation of the KCNQ1-KCNE1 potassium channel
-
Marx S.O., Kurokawa J., Reiken S., Motoike H., D'Armiento J., Marks A.R., Kass R.S. Requirement of a macromolecular signaling complex for beta adrenergic receptor modulation of the KCNQ1-KCNE1 potassium channel. Science 2002, 295:496-499.
-
(2002)
Science
, vol.295
, pp. 496-499
-
-
Marx, S.O.1
Kurokawa, J.2
Reiken, S.3
Motoike, H.4
D'Armiento, J.5
Marks, A.R.6
Kass, R.S.7
-
21
-
-
0035895592
-
AKAP-mediated targeting of protein kinase a regulates contractility in cardiac myocytes
-
Fink M.A., Zakhary D.R., Mackey J.A., Desnoyer R.W., Apperson-Hansen C., Damron D.S., Bond M. AKAP-mediated targeting of protein kinase a regulates contractility in cardiac myocytes. Circ. Res. 2001, 88:291-297.
-
(2001)
Circ. Res.
, vol.88
, pp. 291-297
-
-
Fink, M.A.1
Zakhary, D.R.2
Mackey, J.A.3
Desnoyer, R.W.4
Apperson-Hansen, C.5
Damron, D.S.6
Bond, M.7
-
22
-
-
59449102704
-
Disruption of protein kinase A interaction with A-kinase-anchoring proteins in the heart in vivo: effects on cardiac contractility, protein kinase A phosphorylation, and troponin I proteolysis
-
McConnell B.K., Popovic Z., Mal N., Lee K., Bautista J., Forudi F., Schwartzman R., Jin J.P., Penn M., Bond M. Disruption of protein kinase A interaction with A-kinase-anchoring proteins in the heart in vivo: effects on cardiac contractility, protein kinase A phosphorylation, and troponin I proteolysis. J. Biol. Chem. 2009, 284:1583-1592.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 1583-1592
-
-
McConnell, B.K.1
Popovic, Z.2
Mal, N.3
Lee, K.4
Bautista, J.5
Forudi, F.6
Schwartzman, R.7
Jin, J.P.8
Penn, M.9
Bond, M.10
-
23
-
-
79953189372
-
Small molecule AKAP-protein kinase A (PKA) interaction disruptors that activate PKA interfere with compartmentalized cAMP signaling in cardiac myocytes
-
Christian F., Szaszak M., Friedl S., Drewianka S., Lorenz D., Goncalves A., Furkert J., Vargas C., Schmieder P., Gotz F., Zuhlke K., Moutty M., Gottert H., Joshi M., Reif B., Haase H., Morano I., Grossmann S., Klukovits A., Verli J., Gaspar R., Noack C., Bergmann M., Kass R., Hampel K., Kashin D., Genieser H.G., Herberg F.W., Willoughby D., Cooper D.M., Baillie G.S., Houslay M.D., von Kries J.P., Zimmermann B., Rosenthal W., Klussmann E. Small molecule AKAP-protein kinase A (PKA) interaction disruptors that activate PKA interfere with compartmentalized cAMP signaling in cardiac myocytes. J. Biol. Chem. 2011, 286:9079-9096.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 9079-9096
-
-
Christian, F.1
Szaszak, M.2
Friedl, S.3
Drewianka, S.4
Lorenz, D.5
Goncalves, A.6
Furkert, J.7
Vargas, C.8
Schmieder, P.9
Gotz, F.10
Zuhlke, K.11
Moutty, M.12
Gottert, H.13
Joshi, M.14
Reif, B.15
Haase, H.16
Morano, I.17
Grossmann, S.18
Klukovits, A.19
Verli, J.20
Gaspar, R.21
Noack, C.22
Bergmann, M.23
Kass, R.24
Hampel, K.25
Kashin, D.26
Genieser, H.G.27
Herberg, F.W.28
Willoughby, D.29
Cooper, D.M.30
Baillie, G.S.31
Houslay, M.D.32
von Kries, J.P.33
Zimmermann, B.34
Rosenthal, W.35
Klussmann, E.36
more..
-
24
-
-
77956239101
-
Disruption of protein kinase A localization using a trans-activator of transcription (TAT)-conjugated A-kinase-anchoring peptide reduces cardiac function
-
Patel H.H., Hamuro L.L., Chun B.J., Kawaraguchi Y., Quick A., Rebolledo B., Pennypacker J., Thurston J., Rodriguez-Pinto N., Self C., Olson G., Insel P.A., Giles W.R., Taylor S.S., Roth D.M. Disruption of protein kinase A localization using a trans-activator of transcription (TAT)-conjugated A-kinase-anchoring peptide reduces cardiac function. J. Biol. Chem. 2010, 285:27632-27640.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 27632-27640
-
-
Patel, H.H.1
Hamuro, L.L.2
Chun, B.J.3
Kawaraguchi, Y.4
Quick, A.5
Rebolledo, B.6
Pennypacker, J.7
Thurston, J.8
Rodriguez-Pinto, N.9
Self, C.10
Olson, G.11
Insel, P.A.12
Giles, W.R.13
Taylor, S.S.14
Roth, D.M.15
-
25
-
-
77950473713
-
A-kinase anchoring proteins: getting to the heart of the matter
-
Scott J.D., Santana L.F. A-kinase anchoring proteins: getting to the heart of the matter. Circulation 2010, 121:1264-1271.
-
(2010)
Circulation
, vol.121
, pp. 1264-1271
-
-
Scott, J.D.1
Santana, L.F.2
-
26
-
-
35148828429
-
Hypoxia-inducible factor 1 (HIF-1) pathway
-
Semenza G.L. Hypoxia-inducible factor 1 (HIF-1) pathway. Sci. STKE 2007, cm8.
-
(2007)
Sci. STKE
-
-
Semenza, G.L.1
-
27
-
-
85047682984
-
Regulation of oxygen homeostasis by hypoxia-inducible factor 1
-
Semenza G.L. Regulation of oxygen homeostasis by hypoxia-inducible factor 1. Physiology 2009, 24:97-106.
-
(2009)
Physiology
, vol.24
, pp. 97-106
-
-
Semenza, G.L.1
-
28
-
-
0035917808
-
2-regulated prolyl hydroxylation
-
2-regulated prolyl hydroxylation. Science 2001, 292:468-472.
-
(2001)
Science
, vol.292
, pp. 468-472
-
-
Jaakkola, P.1
Mole, D.R.2
Tian, Y.M.3
Wilson, M.I.4
Gielbert, J.5
Gaskell, S.J.6
Kriegsheim, A.7
Hebestreit, H.F.8
Mukherji, M.9
Schofield, C.J.10
Maxwell, P.H.11
Pugh, C.W.12
Ratcliffe, P.J.13
-
29
-
-
0033587146
-
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
-
Maxwell P.H., Wiesener M.S., Chang G.W., Clifford S.C., Vaux E.C., Cockman M.E., Wykoff C.C., Pugh C.W., Maher E.R., Ratcliffe P.J. The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis. Nature 1999, 399:271-275.
-
(1999)
Nature
, vol.399
, pp. 271-275
-
-
Maxwell, P.H.1
Wiesener, M.S.2
Chang, G.W.3
Clifford, S.C.4
Vaux, E.C.5
Cockman, M.E.6
Wykoff, C.C.7
Pugh, C.W.8
Maher, E.R.9
Ratcliffe, P.J.10
-
30
-
-
2942731503
-
Siah2 regulates stability of prolyl-hydroxylases, controls HIF1alpha abundance, and modulates physiological responses to hypoxia
-
Nakayama K., Frew I.J., Hagensen M., Skals M., Habelhah H., Bhoumik A., Kadoya T., Erdjument-Bromage H., Tempst P., Frappell P.B., Bowtell D.D., Ronai Z. Siah2 regulates stability of prolyl-hydroxylases, controls HIF1alpha abundance, and modulates physiological responses to hypoxia. Cell 2004, 117:941-952.
-
(2004)
Cell
, vol.117
, pp. 941-952
-
-
Nakayama, K.1
Frew, I.J.2
Hagensen, M.3
Skals, M.4
Habelhah, H.5
Bhoumik, A.6
Kadoya, T.7
Erdjument-Bromage, H.8
Tempst, P.9
Frappell, P.B.10
Bowtell, D.D.11
Ronai, Z.12
-
31
-
-
58749099474
-
MAKAP compartmentalizes oxygen-dependent control of HIF-1alpha
-
Wong W., Goehring A.S., Kapiloff M.S., Langeberg L.K., Scott J.D. mAKAP compartmentalizes oxygen-dependent control of HIF-1alpha. Sci. Signal. 2008, 1:ra18.
-
(2008)
Sci. Signal.
, vol.1
-
-
Wong, W.1
Goehring, A.S.2
Kapiloff, M.S.3
Langeberg, L.K.4
Scott, J.D.5
-
32
-
-
33745274726
-
Mitochondria: dynamic organelles in disease, aging, and development
-
Chan D.C. Mitochondria: dynamic organelles in disease, aging, and development. Cell 2006, 125:1241-1252.
-
(2006)
Cell
, vol.125
, pp. 1241-1252
-
-
Chan, D.C.1
-
33
-
-
45349094984
-
Mitochondrial dynamics and apoptosis
-
Suen D.F., Norris K.L., Youle R.J. Mitochondrial dynamics and apoptosis. Genes Dev. 2008, 22:1577-1590.
-
(2008)
Genes Dev.
, vol.22
, pp. 1577-1590
-
-
Suen, D.F.1
Norris, K.L.2
Youle, R.J.3
-
34
-
-
77952236126
-
Inhibiting mitochondrial fission protects the heart against ischemia/reperfusion injury
-
Ong S.B., Subrayan S., Lim S.Y., Yellon D.M., Davidson S.M., Hausenloy D.J. Inhibiting mitochondrial fission protects the heart against ischemia/reperfusion injury. Circulation 2010, 121:2012-2022.
-
(2010)
Circulation
, vol.121
, pp. 2012-2022
-
-
Ong, S.B.1
Subrayan, S.2
Lim, S.Y.3
Yellon, D.M.4
Davidson, S.M.5
Hausenloy, D.J.6
-
35
-
-
0035166814
-
Dynamin-related protein Drp1 is required for mitochondrial division in mammalian cells
-
Smirnova E., Griparic L., Shurland D.L., van der Bliek A.M. Dynamin-related protein Drp1 is required for mitochondrial division in mammalian cells. Mol. Biol. Cell 2001, 12:2245-2256.
-
(2001)
Mol. Biol. Cell
, vol.12
, pp. 2245-2256
-
-
Smirnova, E.1
Griparic, L.2
Shurland, D.L.3
van der Bliek, A.M.4
-
36
-
-
33745026786
-
GTP-dependent twisting of dynamin implicates constriction and tension in membrane fission
-
Roux A., Uyhazi K., Frost A., De Camilli P. GTP-dependent twisting of dynamin implicates constriction and tension in membrane fission. Nature 2006, 441:528-531.
-
(2006)
Nature
, vol.441
, pp. 528-531
-
-
Roux, A.1
Uyhazi, K.2
Frost, A.3
De Camilli, P.4
-
37
-
-
0030903895
-
Identification of a novel dual specificity protein kinase A anchoring protein, D-AKAP1
-
Huang L.J., Durick K., Weiner J.A., Chun J., Taylor S.S. Identification of a novel dual specificity protein kinase A anchoring protein, D-AKAP1. J. Biol. Chem. 1997, 272:8057-8064.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 8057-8064
-
-
Huang, L.J.1
Durick, K.2
Weiner, J.A.3
Chun, J.4
Taylor, S.S.5
-
38
-
-
81355133169
-
Fine-tuning of Drp1/Fis1 availability by AKAP121/Siah2 regulates mitochondrial adaptation to hypoxia
-
Kim H., Scimia M.C., Wilkinson D., Trelles R.D., Wood M.R., Bowtell D., Dillin A., Mercola M., Ronai Z.A. Fine-tuning of Drp1/Fis1 availability by AKAP121/Siah2 regulates mitochondrial adaptation to hypoxia. Mol. Cell 2011, 44:532-544.
-
(2011)
Mol. Cell
, vol.44
, pp. 532-544
-
-
Kim, H.1
Scimia, M.C.2
Wilkinson, D.3
Trelles, R.D.4
Wood, M.R.5
Bowtell, D.6
Dillin, A.7
Mercola, M.8
Ronai, Z.A.9
-
39
-
-
77956602248
-
AKAP121 downregulation impairs protective cAMP signals, promotes mitochondrial dysfunction, and increases oxidative stress
-
Perrino C., Feliciello A., Schiattarella G.G., Esposito G., Guerriero R., Zaccaro L., Del Gatto A., Saviano M., Garbi C., Carangi R., Di Lorenzo E., Donato G., Indolfi C., Avvedimento V.E., Chiariello M. AKAP121 downregulation impairs protective cAMP signals, promotes mitochondrial dysfunction, and increases oxidative stress. Cardiovasc. Res. 2010, 88:101-110.
-
(2010)
Cardiovasc. Res.
, vol.88
, pp. 101-110
-
-
Perrino, C.1
Feliciello, A.2
Schiattarella, G.G.3
Esposito, G.4
Guerriero, R.5
Zaccaro, L.6
Del Gatto, A.7
Saviano, M.8
Garbi, C.9
Carangi, R.10
Di Lorenzo, E.11
Donato, G.12
Indolfi, C.13
Avvedimento, V.E.14
Chiariello, M.15
-
40
-
-
0033120591
-
Phosphorylation and inactivation of BAD by mitochondria-anchored protein kinase A
-
Harada H., Becknell B., Wilm M., Mann M., Huang L.J., Taylor S.S., Scott J.D., Korsmeyer S.J. Phosphorylation and inactivation of BAD by mitochondria-anchored protein kinase A. Mol. Cell 1999, 3:413-422.
-
(1999)
Mol. Cell
, vol.3
, pp. 413-422
-
-
Harada, H.1
Becknell, B.2
Wilm, M.3
Mann, M.4
Huang, L.J.5
Taylor, S.S.6
Scott, J.D.7
Korsmeyer, S.J.8
-
41
-
-
0037423304
-
Essential role of A-kinase anchor protein 121 for cAMP signaling to mitochondria
-
Affaitati A., Cardone L., de Cristofaro T., Carlucci A., Ginsberg M.D., Varrone S., Gottesman M.E., Avvedimento E.V., Feliciello A. Essential role of A-kinase anchor protein 121 for cAMP signaling to mitochondria. J. Biol. Chem. 2003, 278:4286-4294.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 4286-4294
-
-
Affaitati, A.1
Cardone, L.2
de Cristofaro, T.3
Carlucci, A.4
Ginsberg, M.D.5
Varrone, S.6
Gottesman, M.E.7
Avvedimento, E.V.8
Feliciello, A.9
-
42
-
-
0030969371
-
The cellular and molecular response of cardiac myocytes to mechanical stress
-
Sadoshima J., Izumo S. The cellular and molecular response of cardiac myocytes to mechanical stress. Annu. Rev. Physiol. 1997, 59:551-571.
-
(1997)
Annu. Rev. Physiol.
, vol.59
, pp. 551-571
-
-
Sadoshima, J.1
Izumo, S.2
-
43
-
-
2942751868
-
Mechanical stress activates angiotensin II type 1 receptor without the involvement of angiotensin II
-
Zou Y., Akazawa H., Qin Y., Sano M., Takano H., Minamino T., Makita N., Iwanaga K., Zhu W., Kudoh S., Toko H., Tamura K., Kihara M., Nagai T., Fukamizu A., Umemura S., Iiri T., Fujita T., Komuro I. Mechanical stress activates angiotensin II type 1 receptor without the involvement of angiotensin II. Nat. Cell Biol. 2004, 6:499-506.
-
(2004)
Nat. Cell Biol.
, vol.6
, pp. 499-506
-
-
Zou, Y.1
Akazawa, H.2
Qin, Y.3
Sano, M.4
Takano, H.5
Minamino, T.6
Makita, N.7
Iwanaga, K.8
Zhu, W.9
Kudoh, S.10
Toko, H.11
Tamura, K.12
Kihara, M.13
Nagai, T.14
Fukamizu, A.15
Umemura, S.16
Iiri, T.17
Fujita, T.18
Komuro, I.19
-
44
-
-
33645747309
-
The Rac and Rho hall of fame: a decade of hypertrophic signaling hits
-
Brown J.H., Del Re D.P., Sussman M.A. The Rac and Rho hall of fame: a decade of hypertrophic signaling hits. Circ. Res. 2006, 98:730-742.
-
(2006)
Circ. Res.
, vol.98
, pp. 730-742
-
-
Brown, J.H.1
Del Re, D.P.2
Sussman, M.A.3
-
45
-
-
30544452653
-
The mAKAP complex participates in the induction of cardiac myocyte hypertrophy by adrenergic receptor signaling
-
Pare G.C., Bauman A.L., McHenry M., Michel J.J., Dodge-Kafka K.L., Kapiloff M.S. The mAKAP complex participates in the induction of cardiac myocyte hypertrophy by adrenergic receptor signaling. J. Cell Sci. 2005, 118:5637-5646.
-
(2005)
J. Cell Sci.
, vol.118
, pp. 5637-5646
-
-
Pare, G.C.1
Bauman, A.L.2
McHenry, M.3
Michel, J.J.4
Dodge-Kafka, K.L.5
Kapiloff, M.S.6
-
46
-
-
25644452031
-
The protein kinase A anchoring protein mAKAP coordinates two integrated cAMP effector pathways
-
Dodge-Kafka K.L., Soughayer J., Pare G.C., Carlisle Michel J.J., Langeberg L.K., Kapiloff M.S., Scott J.D. The protein kinase A anchoring protein mAKAP coordinates two integrated cAMP effector pathways. Nature 2005, 437:574-578.
-
(2005)
Nature
, vol.437
, pp. 574-578
-
-
Dodge-Kafka, K.L.1
Soughayer, J.2
Pare, G.C.3
Carlisle Michel, J.J.4
Langeberg, L.K.5
Kapiloff, M.S.6
Scott, J.D.7
-
47
-
-
74149093368
-
The mAKAPbeta scaffold regulates cardiac myocyte hypertrophy via recruitment of activated calcineurin
-
Li J., Negro A., Lopez J., Bauman A.L., Henson E., Dodge-Kafka K., Kapiloff M.S. The mAKAPbeta scaffold regulates cardiac myocyte hypertrophy via recruitment of activated calcineurin. J. Mol. Cell. Cardiol. 2010, 48:387-394.
-
(2010)
J. Mol. Cell. Cardiol.
, vol.48
, pp. 387-394
-
-
Li, J.1
Negro, A.2
Lopez, J.3
Bauman, A.L.4
Henson, E.5
Dodge-Kafka, K.6
Kapiloff, M.S.7
-
48
-
-
34547166141
-
The A-kinase anchoring protein (AKAP)-Lbc-signaling complex mediates alpha1 adrenergic receptor-induced cardiomyocyte hypertrophy
-
Appert-Collin A., Cotecchia S., Nenniger-Tosato M., Pedrazzini T., Diviani D. The A-kinase anchoring protein (AKAP)-Lbc-signaling complex mediates alpha1 adrenergic receptor-induced cardiomyocyte hypertrophy. Proc. Natl. Acad. Sci. U. S. A. 2007, 104:10140-10145.
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 10140-10145
-
-
Appert-Collin, A.1
Cotecchia, S.2
Nenniger-Tosato, M.3
Pedrazzini, T.4
Diviani, D.5
-
49
-
-
63349098954
-
The A-kinase anchor protein AKAP121 is a negative regulator of cardiomyocyte hypertrophy
-
Abrenica B., AlShaaban M., Czubryt M.P. The A-kinase anchor protein AKAP121 is a negative regulator of cardiomyocyte hypertrophy. J. Mol. Cell. Cardiol. 2009, 46:674-681.
-
(2009)
J. Mol. Cell. Cardiol.
, vol.46
, pp. 674-681
-
-
Abrenica, B.1
AlShaaban, M.2
Czubryt, M.P.3
-
50
-
-
0034789448
-
MAKAP and the ryanodine receptor are part of a multi-component signaling complex on the cardiomyocyte nuclear envelope
-
Kapiloff M.S., Jackson N., Airhart N. mAKAP and the ryanodine receptor are part of a multi-component signaling complex on the cardiomyocyte nuclear envelope. J. Cell Sci. 2001, 114:3167-3176.
-
(2001)
J. Cell Sci.
, vol.114
, pp. 3167-3176
-
-
Kapiloff, M.S.1
Jackson, N.2
Airhart, N.3
-
51
-
-
0035355360
-
Activated MEK5 induces serial assembly of sarcomeres and eccentric cardiac hypertrophy
-
Nicol R.L., Frey N., Pearson G., Cobb M., Richardson J., Olson E.N. Activated MEK5 induces serial assembly of sarcomeres and eccentric cardiac hypertrophy. EMBO J. 2001, 20:2757-2767.
-
(2001)
EMBO J.
, vol.20
, pp. 2757-2767
-
-
Nicol, R.L.1
Frey, N.2
Pearson, G.3
Cobb, M.4
Richardson, J.5
Olson, E.N.6
-
52
-
-
0035901502
-
MAKAP assembles a protein kinase A/PDE4 phosphodiesterase cAMP signaling module
-
Dodge K.L., Khouangsathiene S., Kapiloff M.S., Mouton R., Hill E.V., Houslay M.D., Langeberg L.K., Scott J.D. mAKAP assembles a protein kinase A/PDE4 phosphodiesterase cAMP signaling module. EMBO J. 2001, 20:1921-1930.
-
(2001)
EMBO J.
, vol.20
, pp. 1921-1930
-
-
Dodge, K.L.1
Khouangsathiene, S.2
Kapiloff, M.S.3
Mouton, R.4
Hill, E.V.5
Houslay, M.D.6
Langeberg, L.K.7
Scott, J.D.8
-
53
-
-
79959572816
-
Phospholipase C epsilon scaffolds to muscle-specific A kinase anchoring protein (mAKAPbeta) and integrates multiple hypertrophic stimuli in cardiac myocytes
-
Zhang L., Malik S., Kelley G.G., Kapiloff M.S., Smrcka A.V. Phospholipase C epsilon scaffolds to muscle-specific A kinase anchoring protein (mAKAPbeta) and integrates multiple hypertrophic stimuli in cardiac myocytes. J. Biol. Chem. 2011, 286:23012-23021.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 23012-23021
-
-
Zhang, L.1
Malik, S.2
Kelley, G.G.3
Kapiloff, M.S.4
Smrcka, A.V.5
-
54
-
-
33748323383
-
Regulation of cardiac hypertrophy by intracellular signalling pathways
-
Heineke J., Molkentin J.D. Regulation of cardiac hypertrophy by intracellular signalling pathways. Nat. Rev. Mol. Cell Biol. 2006, 7:589-600.
-
(2006)
Nat. Rev. Mol. Cell Biol.
, vol.7
, pp. 589-600
-
-
Heineke, J.1
Molkentin, J.D.2
-
55
-
-
0035941212
-
AKAP-Lbc anchors protein kinase A and nucleates Galpha 12-selective Rho-mediated stress fiber formation
-
Diviani D., Soderling J., Scott J.D. AKAP-Lbc anchors protein kinase A and nucleates Galpha 12-selective Rho-mediated stress fiber formation. J. Biol. Chem. 2001, 276:44247-44257.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 44247-44257
-
-
Diviani, D.1
Soderling, J.2
Scott, J.D.3
-
56
-
-
53949090573
-
AKAP-Lbc mobilizes a cardiac hypertrophy signaling pathway
-
Carnegie G.K., Soughayer J., Smith F.D., Pedroja B.S., Zhang F., Diviani D., Bristow M.R., Kunkel M.T., Newton A.C., Langeberg L.K., Scott J.D. AKAP-Lbc mobilizes a cardiac hypertrophy signaling pathway. Mol. Cell 2008, 32:169-179.
-
(2008)
Mol. Cell
, vol.32
, pp. 169-179
-
-
Carnegie, G.K.1
Soughayer, J.2
Smith, F.D.3
Pedroja, B.S.4
Zhang, F.5
Diviani, D.6
Bristow, M.R.7
Kunkel, M.T.8
Newton, A.C.9
Langeberg, L.K.10
Scott, J.D.11
-
57
-
-
78649832811
-
AKAP-Lbc enhances cyclic AMP control of the ERK1/2 cascade
-
Smith F.D., Langeberg L.K., Cellurale C., Pawson T., Morrison D.K., Davis R.J., Scott J.D. AKAP-Lbc enhances cyclic AMP control of the ERK1/2 cascade. Nat. Cell Biol. 2010, 12:1242-1249.
-
(2010)
Nat. Cell Biol.
, vol.12
, pp. 1242-1249
-
-
Smith, F.D.1
Langeberg, L.K.2
Cellurale, C.3
Pawson, T.4
Morrison, D.K.5
Davis, R.J.6
Scott, J.D.7
-
58
-
-
79953141982
-
A-kinase anchoring protein (AKAP)-Lbc anchors a PKN-based signaling complex involved in alpha1-adrenergic receptor-induced p38 activation
-
Cariolato L., Cavin S., Diviani D. A-kinase anchoring protein (AKAP)-Lbc anchors a PKN-based signaling complex involved in alpha1-adrenergic receptor-induced p38 activation. J. Biol. Chem. 2011, 286:7925-7937.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 7925-7937
-
-
Cariolato, L.1
Cavin, S.2
Diviani, D.3
-
59
-
-
79251617662
-
Extracellular signal-regulated kinases 1 and 2 regulate the balance between eccentric and concentric cardiac growth
-
Kehat I., Davis J., Tiburcy M., Accornero F., Saba-El-Leil M.K., Maillet M., York A.J., Lorenz J.N., Zimmermann W.H., Meloche S., Molkentin J.D. Extracellular signal-regulated kinases 1 and 2 regulate the balance between eccentric and concentric cardiac growth. Circ. Res. 2010, 108:176-183.
-
(2010)
Circ. Res.
, vol.108
, pp. 176-183
-
-
Kehat, I.1
Davis, J.2
Tiburcy, M.3
Accornero, F.4
Saba-El-Leil, M.K.5
Maillet, M.6
York, A.J.7
Lorenz, J.N.8
Zimmermann, W.H.9
Meloche, S.10
Molkentin, J.D.11
-
60
-
-
77952479238
-
MAPK-activated protein kinase-2 in cardiac hypertrophy and cyclooxygenase-2 regulation in heart
-
Streicher J.M., Ren S., Herschman H., Wang Y. MAPK-activated protein kinase-2 in cardiac hypertrophy and cyclooxygenase-2 regulation in heart. Circ. Res. 2010, 106:1434-1443.
-
(2010)
Circ. Res.
, vol.106
, pp. 1434-1443
-
-
Streicher, J.M.1
Ren, S.2
Herschman, H.3
Wang, Y.4
-
61
-
-
4344642877
-
AKAP-Lbc nucleates a protein kinase D activation scaffold
-
Carnegie G.K., Smith F.D., McConnachie G., Langeberg L.K., Scott J.D. AKAP-Lbc nucleates a protein kinase D activation scaffold. Mol. Cell 2004, 15:889-899.
-
(2004)
Mol. Cell
, vol.15
, pp. 889-899
-
-
Carnegie, G.K.1
Smith, F.D.2
McConnachie, G.3
Langeberg, L.K.4
Scott, J.D.5
-
62
-
-
84865597148
-
The A-kinase anchoring protein AKAP-Lbc facilitates cardioprotective PKA phosphorylation of Hsp20 on Serine 16
-
(Epub ahead of print), doi.org/10.1042/BJ20120570
-
Edwards H.V., Scott J.D., Baillie G.S. The A-kinase anchoring protein AKAP-Lbc facilitates cardioprotective PKA phosphorylation of Hsp20 on Serine 16. Biochem. J. 2012, (Epub ahead of print), doi.org/10.1042/BJ20120570.
-
(2012)
Biochem. J.
-
-
Edwards, H.V.1
Scott, J.D.2
Baillie, G.S.3
-
63
-
-
84856280870
-
PKA phosphorylation of the small heat-shock protein Hsp20 enhances its cardioprotective effects
-
Edwards H.V., Scott J.D., Baillie G.S. PKA phosphorylation of the small heat-shock protein Hsp20 enhances its cardioprotective effects. Biochem. Soc. Trans. 2012, 40:210-214.
-
(2012)
Biochem. Soc. Trans.
, vol.40
, pp. 210-214
-
-
Edwards, H.V.1
Scott, J.D.2
Baillie, G.S.3
-
64
-
-
77950638532
-
The Rho guanine nucleotide exchange factor AKAP13 (BRX) is essential for cardiac development in mice
-
Mayers C.M., Wadell J., McLean K., Venere M., Malik M., Shibata T., Driggers P.H., Kino T., Guo X.C., Koide H., Gorivodsky M., Grinberg A., Mukhopadhyay M., Abu-Asab M., Westphal H., Segars J.H. The Rho guanine nucleotide exchange factor AKAP13 (BRX) is essential for cardiac development in mice. J. Biol. Chem. 2010, 285:12344-12354.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 12344-12354
-
-
Mayers, C.M.1
Wadell, J.2
McLean, K.3
Venere, M.4
Malik, M.5
Shibata, T.6
Driggers, P.H.7
Kino, T.8
Guo, X.C.9
Koide, H.10
Gorivodsky, M.11
Grinberg, A.12
Mukhopadhyay, M.13
Abu-Asab, M.14
Westphal, H.15
Segars, J.H.16
-
65
-
-
4644325723
-
Trends molecular restoration of beta-adrenergic receptor signaling improves contractile function of failing hearts
-
Tevaearai H.T., Koch W.J. Trends molecular restoration of beta-adrenergic receptor signaling improves contractile function of failing hearts. Cardiovasc. Med. 2004, 14:252-256.
-
(2004)
Cardiovasc. Med.
, vol.14
, pp. 252-256
-
-
Tevaearai, H.T.1
Koch, W.J.2
-
66
-
-
0037050009
-
Seven-transmembrane-spanning receptors and heart function
-
Rockman H.A., Koch W.J., Lefkowitz R.J. Seven-transmembrane-spanning receptors and heart function. Nature 2002, 415:206-212.
-
(2002)
Nature
, vol.415
, pp. 206-212
-
-
Rockman, H.A.1
Koch, W.J.2
Lefkowitz, R.J.3
-
67
-
-
0037088608
-
Beta-Arrestin/AP-2 interaction in G protein-coupled receptor internalization: identification of a beta-arrestin binging site in beta 2-adaptin
-
Laporte S.A., Miller W.E., Kim K.M., Caron M.G. beta-Arrestin/AP-2 interaction in G protein-coupled receptor internalization: identification of a beta-arrestin binging site in beta 2-adaptin. J. Biol. Chem. 2002, 277:9247-9254.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 9247-9254
-
-
Laporte, S.A.1
Miller, W.E.2
Kim, K.M.3
Caron, M.G.4
-
68
-
-
0034725650
-
The interaction of beta-arrestin with the AP-2 adaptor is required for the clustering of beta 2-adrenergic receptor into clathrin-coated pits
-
Laporte S.A., Oakley R.H., Holt J.A., Barak L.S., Caron M.G. The interaction of beta-arrestin with the AP-2 adaptor is required for the clustering of beta 2-adrenergic receptor into clathrin-coated pits. J. Biol. Chem. 2000, 275:23120-23126.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 23120-23126
-
-
Laporte, S.A.1
Oakley, R.H.2
Holt, J.A.3
Barak, L.S.4
Caron, M.G.5
-
69
-
-
0036327388
-
Phosphoinositide 3-kinase regulates beta2-adrenergic receptor endocytosis by AP-2 recruitment to the receptor/beta-arrestin complex
-
Naga Prasad S.V., Laporte S.A., Chamberlain D., Caron M.G., Barak L., Rockman H.A. Phosphoinositide 3-kinase regulates beta2-adrenergic receptor endocytosis by AP-2 recruitment to the receptor/beta-arrestin complex. J. Cell Biol. 2002, 158:563-575.
-
(2002)
J. Cell Biol.
, vol.158
, pp. 563-575
-
-
Naga Prasad, S.V.1
Laporte, S.A.2
Chamberlain, D.3
Caron, M.G.4
Barak, L.5
Rockman, H.A.6
-
70
-
-
79953331935
-
Integrating cardiac PIP3 and cAMP signaling through a PKA anchoring function of p110γ
-
Perino A., Ghigo A., Ferrero E., Morello F., Santulli G., Baillie G.S., Damilano F., Dunlop A.J., Pawson C., Walser R., Levi R., Altruda F., Silengo L., Langeberg L.K., Neubauer G., Heyman S., Lembo G., Wymann M.P., Wetzker R., Houslay M.D., Iaccarino G., Scott J.D., Hirsch E. Integrating cardiac PIP3 and cAMP signaling through a PKA anchoring function of p110γ. Mol. Cell 2011, 42:84-95.
-
(2011)
Mol. Cell
, vol.42
, pp. 84-95
-
-
Perino, A.1
Ghigo, A.2
Ferrero, E.3
Morello, F.4
Santulli, G.5
Baillie, G.S.6
Damilano, F.7
Dunlop, A.J.8
Pawson, C.9
Walser, R.10
Levi, R.11
Altruda, F.12
Silengo, L.13
Langeberg, L.K.14
Neubauer, G.15
Heyman, S.16
Lembo, G.17
Wymann, M.P.18
Wetzker, R.19
Houslay, M.D.20
Iaccarino, G.21
Scott, J.D.22
Hirsch, E.23
more..
-
71
-
-
0034724376
-
Regulation of PKA binding to AKAPs in the heart: alterations in human heart failure
-
Zakhary D.R., Moravec C.S., Bond M. Regulation of PKA binding to AKAPs in the heart: alterations in human heart failure. Circulation 2000, 101:1459-1464.
-
(2000)
Circulation
, vol.101
, pp. 1459-1464
-
-
Zakhary, D.R.1
Moravec, C.S.2
Bond, M.3
-
72
-
-
12244296453
-
Inhibition of cardiac myofibroblast formation and collagen synthesis by activation and overexpression of adenylyl cyclase
-
Swaney J.S., Roth D.M., Olson E.R., Naugle J.E., Meszaros J.G., Insel P.A. Inhibition of cardiac myofibroblast formation and collagen synthesis by activation and overexpression of adenylyl cyclase. Proc. Natl. Acad. Sci. U. S. A. 2005, 102:437-442.
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 437-442
-
-
Swaney, J.S.1
Roth, D.M.2
Olson, E.R.3
Naugle, J.E.4
Meszaros, J.G.5
Insel, P.A.6
-
73
-
-
0023760533
-
Phosphorylation of myocardial fructose-6-phosphate,2-kinase: fructose-2,6-bisphosphatase by cAMP-dependent protein kinase and protein kinase C. Activation by phosphorylation and amino acid sequences of the phosphorylation sites
-
Kitamura K., Kangawa K., Matsuo H., Uyeda K. Phosphorylation of myocardial fructose-6-phosphate,2-kinase: fructose-2,6-bisphosphatase by cAMP-dependent protein kinase and protein kinase C. Activation by phosphorylation and amino acid sequences of the phosphorylation sites. J. Biol. Chem. 1988, 263:16796-16801.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 16796-16801
-
-
Kitamura, K.1
Kangawa, K.2
Matsuo, H.3
Uyeda, K.4
-
74
-
-
0030748651
-
Phosphorylation and activation of heart 6-phosphofructo-2-kinase by protein kinase B and other protein kinases of the insulin signaling cascades
-
Deprez J., Vertommen D., Alessi D.R., Hue L., Rider M.H. Phosphorylation and activation of heart 6-phosphofructo-2-kinase by protein kinase B and other protein kinases of the insulin signaling cascades. J. Biol. Chem. 1997, 272:17269-17275.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 17269-17275
-
-
Deprez, J.1
Vertommen, D.2
Alessi, D.R.3
Hue, L.4
Rider, M.H.5
-
75
-
-
0036173161
-
The NADH: ubiquinone oxidoreductase (complex I) of the mammalian respiratory chain and the cAMP cascade
-
Papa S., Sardanelli A.M., Scacco S., Petruzzella V., Technikova-Dobrova Z., Vergari R., Signorile A. The NADH: ubiquinone oxidoreductase (complex I) of the mammalian respiratory chain and the cAMP cascade. J. Bioenerg. Biomembr. 2002, 34:1-10.
-
(2002)
J. Bioenerg. Biomembr.
, vol.34
, pp. 1-10
-
-
Papa, S.1
Sardanelli, A.M.2
Scacco, S.3
Petruzzella, V.4
Technikova-Dobrova, Z.5
Vergari, R.6
Signorile, A.7
|