Hepatic leukemia factor promotes resistance to cell death: Implications for therapeutics and chronotherapy

Toxicology and Applied Pharmacology

Volumn 268, Issue 2, 2013, Pages 141-148

  Waters, Katrina M ^a   Sontag, Ryan L ^a   Weber, Thomas J ^a  

^a PACIFIC NORTHWEST NATIONAL LABORATORY   (United States)

Author keywords

Apoptosis; Circadian; Gene regulation; PAR bZIP; Therapeutics

Indexed keywords

BASIC LEUCINE ZIPPER TRANSCRIPTION FACTOR; HEPATIC LEUKEMIA FACTOR; LACTATE DEHYDROGENASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL ADHESION; CELL COUNT; CELL PROTECTION; CELL VIABILITY; CHRONOTHERAPY; CIRCADIAN RHYTHM; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; GENE; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IONIZING RADIATION; KERATINOCYTE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN MICROARRAY; RADIATION DOSE; SERUM; SIGNAL NOISE RATIO; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; ANNEXINS; APOPTOSIS; BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS; CASPASE 3; CELL SURVIVAL; CELLS, CULTURED; CIRCADIAN RHYTHM; HUMANS; MICE; MICRONUCLEI, CHROMOSOME-DEFECTIVE; NEOPLASMS; RNA, MESSENGER; TRANSDUCTION, GENETIC;

EID: 84875071011     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2013.01.031     Document Type: Article

References (63)

1. Abdollahi A. LOT1 (ZAC1/PLAGL1) and its family members: mechanisms and functions. J. Cell. Physiol. 2007, 210:16-25.
2. Aglipay J.A., Lee S.W., Okada S., Fujiuchi N., Ohtsuka T., Kwak J.C., Wang Y., Johnstone R.W., Deng C., Qin J., Ouchi T. A member of the Pyrin family, IFI16, is a novel BRCA1-associated protein involved in the p53-mediated apoptosis pathway. Oncogene 2003, 22:8931-8938.
3. Banu S.K., Lee J., Speights V.O., Starzinski-Powitz A., Arosh J.A. Selective inhibition of prostaglandin E2 receptors EP2 and EP4 induces apoptosis of human endometriotic cells through suppression of ERK1/2, AKT, NFkappaB, and beta-catenin pathways and activation of intrinsic apoptotic mechanisms. Mol. Endocrinol. 2009, 23:1291-1305.
4. Benito A., Gutierrez O., Pipaon C., Real P.J., Gachon F., Ritchie A.E., Fernandez-Luna J.L. A novel role for proline- and acid-rich basic region leucine zipper (PAR bZIP) proteins in the transcriptional regulation of a BH3-only proapoptotic gene. J. Biol. Chem. 2006, 281:38351-38357.
5. Benjamini Y., Hochberg Y. Controlling the false discovery rate-a practical and powerful approach to multiple testing. J. R. Stat. Soc. B Methodol. 1995, 57:289-300.
6. Bolstad B.M., Irizarry R.A., Astrand M., Speed T.P. A comparison of normalization methods for high density oligonucleotide array data based on variance and bias. Bioinformatics (Oxford, England) 2003, 19:185-193.
7. Bolt H.M. Interactions between clinically used drugs and oral contraceptives. Environ. Health Perspect. 1994, 102(Suppl. 9):35-38.
8. Bonassi S., El-Zein R., Bolognesi C., Fenech M. Micronuclei frequency in peripheral blood lymphocytes and cancer risk: evidence from human studies. Mutagenesis 2011, 26:93-100.
9. Bozek K., Relogio A., Kielbasa S.M., Heine M., Dame C., Kramer A., Herzel H. Regulation of clock-controlled genes in mammals. PLoS One 2009, 4:e4882.
10. Casteel M., Nielsen C., Kothlow S., Dietrich R., Martlbauer E. Impact of DUSP1 on the apoptotic potential of deoxynivalenol in the epithelial cell line HepG2. Toxicol. Lett. 2010, 199:43-50.
11. de Bessa Garcia S.A., Pereira M.C., Nagai M.A. Expression pattern of the pro-apoptotic gene PAR-4 during the morphogenesis of MCF-10A human mammary epithelial cells. Cancer Microenviron. 2010, 4:33-38.
12. Dennis G., Sherman B.T., Hosack D.A., Yang J., Gao W., Lane H.C., Lempicki R.A. DAVID: database for annotation, visualization, and integrated discovery. Genome Biol. 2003, 4:R60.
13. Destici E., Oklejewicz M., Saito S., van der Horst G.T. Mammalian cryptochromes impinge on cell cycle progression in a circadian clock-independent manner. Cell Cycle 2011, 10:3788-3797.
14. Diener T., Neuhaus M., Koziel R., Micutkova L., Jansen-Durr P. Role of endonuclease G in senescence-associated cell death of human endothelial cells. Exp. Gerontol. 2010, 45:638-644.
15. Dorn D.C., Kou C.A., Png K.J., Moore M.A. The effect of cantharidins on leukemic stem cells. Int. J. Cancer 2009, 124:2186-2199.
16. Falvey E., Fleury-Olela F., Schibler U. The rat hepatic leukemia factor (HLF) gene encodes two transcriptional activators with distinct circadian rhythms, tissue distributions and target preferences. EMBO J. 1995, 14:4307-4317.
17. Figueroa J.D., Benton R.L., Velazquez I., Torrado A.I., Ortiz C.M., Hernandez C.M., Diaz J.J., Magnuson D.S., Whittemore S.R., Miranda J.D. Inhibition of EphA7 up-regulation after spinal cord injury reduces apoptosis and promotes locomotor recovery. J. Neurosci. Res. 2006, 84:1438-1451.
18. Filipski E., Li X.M., Levi F. Disruption of circadian coordination and malignant growth. Cancer Causes Control 2006, 17:509-514.
19. Gachon F. Physiological function of PARbZip circadian clock-controlled transcription factors. Ann. Med. 2007, 39:562-571.
20. Gachon F., Olela F.F., Schaad O., Descombes P., Schibler U. The circadian PAR-domain basic leucine zipper transcription factors DBP, TEF, and HLF modulate basal and inducible xenobiotic detoxification. Cell Metab. 2006, 4:25-36.
21. Guengerich F.P. Human cytochrome P450 enzymes. Cytochrome P450: Structure, Mechanisms, and Biochemistry 1995, 473-535. Plenum Press. P.R. Ortiz de Montellano (Ed.).
22. Han H.J., Tokino T., Nakamura Y. CSR, a scavenger receptor-like protein with a protective role against cellular damage caused by UV irradiation and oxidative stress. Hum. Mol. Genet. 1998, 7:1039-1046.
23. Hart G.T., Wang X., Hogquist K.A., Jameson S.C. Kruppel-like factor 2 (KLF2) regulates B-cell reactivity, subset differentiation, and trafficking molecule expression. Proc. Natl. Acad. Sci. U. S. A. 2011, 108:716-721.
24. Hashiramoto A., Yamane T., Tsumiyama K., Yoshida K., Komai K., Yamada H., Yamazaki F., Doi M., Okamura H., Shiozawa S. Mammalian clock gene cryptochrome regulates arthritis via proinflammatory cytokine TNF-alpha. J. Immunol. 2010, 184:1560-1565.
25. Haus E. Chronobiology of the mammalian response to ionizing radiation. Potential applications in oncology. Chronobiol. Int. 2002, 19:77-100.
26. Honda H., Inaba T., Suzuki T., Oda H., Ebihara Y., Tsuiji K., Nakahata T., Ishikawa T., Yazaki Y., Hirai H. Expression of E2A-HLF chimeric protein induced T-cell apoptosis, B-cell maturation arrest, and development of acute lymphoblastic leukemia. Blood 1999, 93:2780-2790.
27. Hu Y., Wang T., Stormo G.D., Gordon J.I. RNA interference of achaete-scute homolog 1 in mouse prostate neuroendocrine cells reveals its gene targets and DNA binding sites. Proc. Natl. Acad. Sci. U. S. A. 2004, 101:5559-5564.
28. Hu Z., Dandekar D., O'Shaughnessy P.J., De Gendt K., Verhoeven G., Wilkinson M.F. Androgen-induced Rhox homeobox genes modulate the expression of AR-regulated genes. Mol. Endocrinol. 2010, 24:60-75.
29. Inaba T., Inukai T., Yoshihara T., Seyschab H., Ashmun R.A., Canman C.E., Laken S.J., Kastan M.B., Look A.T. Reversal of apoptosis by the leukaemia-associated E2A-HLF chimaeric transcription factor. Nature 1996, 382:541-544.
30. Inaba T., Roberts W.M., Shapiro L.H., Jolly K.W., Raimondi S.C., Smith S.D., Look A.T. Fusion of the leucine zipper gene HLF to the E2A gene in human acute B-lineage leukemia. Science 1992, 257:531-534.
31. Ishihara H., Tanaka I., Yakumaru H., Chikamori M., Ishihara F., Tanaka M., Ishiwata A., Kurematsu A., Satoh A., Ueda J., Akashi M. Circadian transitions in radiation dose-dependent augmentation of mRNA levels for DNA damage-induced genes elicited by accurate real-time RT-PCR quantification. J. Radiat. Res. 2010, 51:265-275.
32. Jarmalaite S., Laurinaviciene A., Tverkuviene J., Kalinauskaite N., Petroska D., Bohling T., Husgafvel-Pursiainen K. Tumor suppressor gene ZAC/PLAGL1: altered expression and loss of the nonimprinted allele in pheochromocytomas. Cancer Genet. 2011, 204:398-404.
33. Katagiri N., Shobuike T., Chang B., Kukita A., Miyamoto H. The human apoptosis inhibitor NAIP induces pyroptosis in macrophages infected with Legionella pneumophila. Microbes Infect. 2012, 14:1123-1132.
34. Kimzey A.L., Weitz K.K., Guengerich F.P., Zangar R.C. Hydroperoxy-10,12-octadecadienoic acid stimulates cytochrome P450 3A protein aggregation by a mechanism that is inhibited by substrate. Biochemistry 2003, 42:12691-12699.
35. Kurosawa H., Goi K., Inukai T., Inaba T., Chang K.S., Shinjyo T., Rakestraw K.M., Naeve C.W., Look A.T. Two candidate downstream target genes for E2A-HLF. Blood 1999, 93:321-332.
36. Levi F. Chronotherapeutics: the relevance of timing in cancer therapy. Cancer Causes Control 2006, 17:611-621.
37. Levi F., Karaboue A., Gorden L., Innominato P.F., Saffroy R., Giacchetti S., Hauteville D., Guettier C., Adam R., Bouchahda M. Cetuximab and circadian chronomodulated chemotherapy as salvage treatment for metastatic colorectal cancer (mCRC): safety, efficacy and improved secondary surgical resectability. Cancer Chemother. Pharmacol. 2011, 67:339-348.
38. Levi F., Okyar A., Dulong S., Innominato P.F., Clairambault J. Circadian timing in cancer treatments. Annu. Rev. Pharmacol. Toxicol. 2010, 50:377-421.
39. Li L., Abdel Fattah E., Cao G., Ren C., Yang G., Goltsov A.A., Chinault A.C., Cai W.W., Timme T.L., Thompson T.C. Glioma pathogenesis-related protein 1 exerts tumor suppressor activities through proapoptotic reactive oxygen species-c-Jun-NH2 kinase signaling. Cancer Res. 2008, 68:434-443.
40. Li X.M., Kanekal S., Crepin D., Guettier C., Carriere J., Elliott G., Levi F. Circadian pharmacology of l-alanosine (SDX-102) in mice. Mol. Cancer Ther. 2006, 5:337-346.
41. Liu W., Han B., Sun B., Gao Y., Huang Y., Hu M. Overexpression of interleukin-18 induces growth inhibition, apoptosis and gene expression changes in a human tongue squamous cell carcinoma cell line. J. Int. Med. Res. 2012, 40:537-544.
42. Ma L., Xu G., Sotnikova A., Szczepanowski M., Giefing M., Krause K., Krams M., Siebert R., Jin J., Klapper W. Loss of expression of LyGDI (ARHGDIB), a rho GDP-dissociation inhibitor, in Hodgkin lymphoma. Br. J. Haematol. 2007, 139:217-223.
43. Mitsui S., Yamaguchi S., Matsuo T., Ishida Y., Okamura H. Antagonistic role of E4BP4 and PAR proteins in the circadian oscillatory mechanism. Genes Dev. 2001, 15:995-1006.
44. Phan T.C., Ooi J., Goonewardene M.S. A novel molecule, SLURP-1, enhances the survival of periodontal ligament fibroblasts. J. Periodontal. Res. 2010, 45:331-336.
45. Sonpavde G., Thompson T.C., Jain R.K., Ayala G.E., Kurosaka S., Edamura K., Tabata K., Ren C., Goltsov A.A., Mims M.P., Hayes T.G., Ittmann M.M., Wheeler T.M., Gee A., Miles B.J., Kadmon D. GLIPR1 tumor suppressor gene expressed by adenoviral vector as neoadjuvant intraprostatic injection for localized intermediate or high-risk prostate cancer preceding radical prostatectomy. Clin. Cancer Res. 2011, 17:7174-7182.
46. Strasser A., O'Connor L., Dixit V.M. Apoptosis signaling. Annu. Rev. Biochem. 2000, 69:217-245.
47. Suzukawa K., Weber T.J., Colburn N.H. AP-1, NF-kappa-B, and ERK activation thresholds for promotion of neoplastic transformation in the mouse epidermal JB6 model. Environ. Health Perspect. 2002, 110:865-870.
48. Swann K., Whitaker M.J. Second messengers at fertilization in sea-urchin eggs. J. Reprod. Fertil. Suppl. 1990, 42:141-153.
49. Szklarz G.D., Halpert J.R. Molecular modeling of cytochrome P450 3A4. J. Comput. Aided Mol. Des. 1997, 11:265-272.
50. Tanimura N., Kusunose N., Matsunaga N., Koyanagi S., Ohdo S. Aryl hydrocarbon receptor-mediated Cyp1a1 expression is modulated in a CLOCK-dependent circadian manner. Toxicology 2011, 290:203-207.
51. Tao Y., Leteur C., Calderaro J., Girdler F., Zhang P., Frascogna V., Varna M., Opolon P., Castedo M., Bourhis J., Kroemer G., Deutsch E. The aurora B kinase inhibitor AZD1152 sensitizes cancer cells to fractionated irradiation and induces mitotic catastrophe. Cell Cycle 2009, 8:3172-3181.
52. Thummel K.E., Wilkinson G.R. In vitro and in vivo drug interactions involving human CYP3A. Annu. Rev. Pharmacol. Toxicol. 1998, 38:389-430.
53. Tian X.Y., Yung L.H., Wong W.T., Liu J., Leung F.P., Liu L., Chen Y., Kong S.K., Kwan K.M., Ng S.M., Lai P.B., Yung L.M., Yao X., Huang Y. Bone morphogenic protein-4 induces endothelial cell apoptosis through oxidative stress-dependent p38MAPK and JNK pathway. J. Mol. Cell. Cardiol. 2012, 52:237-244.
54. Tong S.W., Yang Y.X., Hu H.D., An X., Ye F., Hu P., Ren H., Li S.L., Zhang D.Z. Proteomic investigation of 5-fluorouracil resistance in a human hepatocellular carcinoma cell line. J. Cell. Biochem. 2011, 113:1671-1680.
55. Ueki K., Fruman D.A., Yballe C.M., Fasshauer M., Klein J., Asano T., Cantley L.C., Kahn C.R. Positive and negative roles of p85 alpha and p85 beta regulatory subunits of phosphoinositide 3-kinase in insulin signaling. J. Biol. Chem. 2003, 278:48453-48466.
56. von Moltke L.L., Greenblatt D.J., Schmider J., Harmatz J.S., Shader R.I. Metabolism of drugs by cytochrome P450 3A isoforms. Implications for drug interactions in psychopharmacology. Clin. Pharmacokinet. 1995, 29(Suppl. 1):33-43. (discussion 43-34).
57. Waters K.M., Tan R., Opresko L.K., Quesenberry R.D., Bandyopadhyay S., Chrisler W.B., Weber T.J. Cellular dichotomy between anchorage-independent growth responses to bFGF and TPA reflects molecular switch in commitment to carcinogenesis. Mol. Carcinog. 2009, 48:1059-1069.
58. Weber T.J., Markillie L.M., Chrisler W.B., Vielhauer G.A., Regan J.W. Modulation of JB6 mouse epidermal cell transformation response by the prostaglandin F2alpha receptor. Mol. Carcinog. 2002, 35:163-172.
59. Weber T.J., Monks T.J., Lau S.S. DDM-PGE(2)-mediated cytoprotection in renal epithelial cells by a thromboxane A(2) receptor coupled to NF-kappaB. Am. J. Physiol. Renal. Physiol. 2000, 278:F270-F278.
60. Weber T.J., Smallwood H.S., Kathmann L.E., Markillie L.M., Squier T.C., Thrall B.D. Functional linkage between tumor necrosis factor biosynthesis and calmodulin-dependent activation of iNOS in RAW 264.7 macrophages. Am. J. Physiol. Cell Physiol. 2006, 290:C1512-C1520.
61. Wu K., Yang Y., Wang C., Davoli M.A., D'Amico M., Li A., Cveklova K., Kozmik Z., Lisanti M.P., Russell R.G., Cvekl A., Pestell R.G. DACH1 inhibits transforming growth factor-beta signaling through binding Smad4. J. Biol. Chem. 2003, 278:51673-51684.
62. Zhang R., Lu Z., Liu T., Soong S.J., Diasio R.B. Relationship between circadian-dependent toxicity of 5-fluorodeoxyuridine and circadian rhythms of pyrimidine enzymes: possible relevance to fluoropyrimidine chemotherapy. Cancer Res. 1993, 53:2816-2822.
63. Zhou W., Wang X., Li L., Feng X., Yang Z., Zhang W., Hu R. Depletion of tubulin polymerization promoting protein family member 3 suppresses HeLa cell proliferation. Mol. Cell. Biochem. 2010, 333:91-98.