메뉴 건너뛰기




Volumn 93, Issue 9, 1999, Pages 2780-2790

Expression of E2A-HLF chimeric protein induced T-cell apoptosis, B-cell maturation arrest, and development of acute lymphoblastic leukemia

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR;

EID: 0033135718     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v93.9.2780.409a47_2780_2790     Document Type: Article
Times cited : (37)

References (42)
  • 1
    • 0027970838 scopus 로고
    • Chromosomal translocations in human cancer
    • Rabbitts TH: Chromosomal translocations in human cancer [review]. Nature 372:143, 1994
    • (1994) Nature , vol.372 , pp. 143
    • Rabbitts, T.H.1
  • 2
    • 0025910286 scopus 로고
    • Oncogenic conversion of transcription factors by chromosomal translocations
    • Cleary ML: Oncogenic conversion of transcription factors by chromosomal translocations. Cell 66:619, 1991
    • (1991) Cell , vol.66 , pp. 619
    • Cleary, M.L.1
  • 3
    • 0025137176 scopus 로고
    • A new homeobox gene contributes the DNA binding domain of the t(1;19) translocation protein in pre-B ALL
    • Kamps MP, Murre C, Sun XH, Baltimore D: A new homeobox gene contributes the DNA binding domain of the t(1;19) translocation protein in pre-B ALL. Cell 60:547, 1990
    • (1990) Cell , vol.60 , pp. 547
    • Kamps, M.P.1    Murre, C.2    Sun, X.H.3    Baltimore, D.4
  • 4
    • 0025064238 scopus 로고
    • Chromosomal translocation t(1;19) results in synthesis of a homeobox fusion mRNA that codes for a potential chimeric transcription factor
    • Nourse J, Mellentin JD, Galili N, Wilkinson J, Stanbridge E, Smith SD, Cleary ML: Chromosomal translocation t(1;19) results in synthesis of a homeobox fusion mRNA that codes for a potential chimeric transcription factor. Cell 60:535, 1990
    • (1990) Cell , vol.60 , pp. 535
    • Nourse, J.1    Mellentin, J.D.2    Galili, N.3    Wilkinson, J.4    Stanbridge, E.5    Smith, S.D.6    Cleary, M.L.7
  • 6
    • 0026761786 scopus 로고
    • HLF, a novel hepatic bZIP protein, shows altered DNA-binding properties following fusion to E2A in t(17;19) acute lymphoblastic leukemia
    • Hunger SP, Ohyashiki K, Toyama K, Cleary ML: HLF, a novel hepatic bZIP protein, shows altered DNA-binding properties following fusion to E2A in t(17;19) acute lymphoblastic leukemia. Genes Dev 6:1608, 1992
    • (1992) Genes Dev , vol.6 , pp. 1608
    • Hunger, S.P.1    Ohyashiki, K.2    Toyama, K.3    Cleary, M.L.4
  • 7
    • 0024554495 scopus 로고
    • A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins
    • Murre C, McCaw PS, Baltimore D: A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins. Cell 56:777, 1989
    • (1989) Cell , vol.56 , pp. 777
    • Murre, C.1    McCaw, P.S.2    Baltimore, D.3
  • 8
    • 0027228167 scopus 로고
    • Localization of E2A mRNA expression in developing and adult rat tissues
    • Roberts VJ, Steenbergen R, Murre C: Localization of E2A mRNA expression in developing and adult rat tissues. Proc Natl Acad Sci USA 90:7583, 1993
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 7583
    • Roberts, V.J.1    Steenbergen, R.2    Murre, C.3
  • 9
    • 0028219456 scopus 로고
    • DNA-binding specificity and trans-activating potential of the leukemia-associated E2A-hepatic leukemia factor fusion protein
    • Inaba T, Shapiro LH, Funabiki T, Sinclair AE, Jones BG, Ashmun RA, Look AT: DNA-binding specificity and trans-activating potential of the leukemia-associated E2A-hepatic leukemia factor fusion protein. Mol Cell Biol 14:3403, 1994
    • (1994) Mol Cell Biol , vol.14 , pp. 3403
    • Inaba, T.1    Shapiro, L.H.2    Funabiki, T.3    Sinclair, A.E.4    Jones, B.G.5    Ashmun, R.A.6    Look, A.T.7
  • 10
    • 0028997689 scopus 로고
    • E2A-HLF-mediated cell transformation requires both the trans-activation domains of E2A and the leucine zipper dimerization domain of HLF
    • Yoshihara T, Inaba T, Shapiro LH, Kato JY, Look AT: E2A-HLF-mediated cell transformation requires both the trans-activation domains of E2A and the leucine zipper dimerization domain of HLF. Mol Cell Biol 15:3247, 1995
    • (1995) Mol Cell Biol , vol.15 , pp. 3247
    • Yoshihara, T.1    Inaba, T.2    Shapiro, L.H.3    Kato, J.Y.4    Look, A.T.5
  • 12
    • 0030899395 scopus 로고    scopus 로고
    • E2A-HLF chimeric transcription factors in pro-B cell acute lymphoblastic leukemia
    • Look AT: E2A-HLF chimeric transcription factors in pro-B cell acute lymphoblastic leukemia. Curr Top Microbiol Immunol 220:45, 1997
    • (1997) Curr Top Microbiol Immunol , vol.220 , pp. 45
    • Look, A.T.1
  • 15
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction
    • Chomczinski P, Sacchi N: Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156, 1987
    • (1987) Anal Biochem , vol.162 , pp. 156
    • Chomczinski, P.1    Sacchi, N.2
  • 17
    • 0025868702 scopus 로고
    • Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow
    • Hardy RR, Carmack CE, Shinton SA, Kemp JD, Hayakawa K: Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow. J Exp Med 173:1213, 1991
    • (1991) J Exp Med , vol.173 , pp. 1213
    • Hardy, R.R.1    Carmack, C.E.2    Shinton, S.A.3    Kemp, J.D.4    Hayakawa, K.5
  • 18
    • 0026327553 scopus 로고
    • Transgenic models of tumor development
    • Adams JM, Cory S: Transgenic models of tumor development. Science 254:1161, 1991
    • (1991) Science , vol.254 , pp. 1161
    • Adams, J.M.1    Cory, S.2
  • 24
    • 0024434881 scopus 로고
    • Strain dependency of B and T lymphoma development in immunoglobulin heavy chain enhancer (Eμ)-myc transgenic mice
    • Yukawa K, Kikutani H, Inomoto T, Uehira M, Bin SH, Akagi K, Yamamura K, Kishimoto T: Strain dependency of B and T lymphoma development in immunoglobulin heavy chain enhancer (Eμ)-myc transgenic mice. J Exp Med 170:711, 1989
    • (1989) J Exp Med , vol.170 , pp. 711
    • Yukawa, K.1    Kikutani, H.2    Inomoto, T.3    Uehira, M.4    Bin, S.H.5    Akagi, K.6    Yamamura, K.7    Kishimoto, T.8
  • 27
    • 0021679848 scopus 로고
    • Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation
    • Tsujimoto Y, Finger LR, Yunis J, C. NP, Croce CM: Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation. Science 226:1097, 1984
    • (1984) Science , vol.226 , pp. 1097
    • Tsujimoto, Y.1    Finger, L.R.2    Yunis, J.3    C, N.P.4    Croce, C.M.5
  • 30
    • 0031656237 scopus 로고    scopus 로고
    • The AD1 and AD2 transactivation domains of E2A are essential for the antiapoptotic activity of the E2A-HLF chimeric oncoprotein
    • Inukai T, Inaba T, Ikushima S, Look AT: The AD1 and AD2 transactivation domains of E2A are essential for the antiapoptotic activity of the E2A-HLF chimeric oncoprotein. Mol Cell Biol 18:6035, 1998
    • (1998) Mol Cell Biol , vol.18 , pp. 6035
    • Inukai, T.1    Inaba, T.2    Ikushima, S.3    Look, A.T.4
  • 31
    • 24244478065 scopus 로고    scopus 로고
    • Downstream target genes for E2A-HLF indentified by cDNA microarray analysis
    • abstr
    • Goi K, Kurosawa H, Inaba T, Meltzer PS, Look AT: Downstream target genes for E2A-HLF indentified by cDNA microarray analysis. Blood 92:590a, 1998 (abstr, suppl 1)
    • (1998) Blood , vol.92 , Issue.SUPPL. 1
    • Goi, K.1    Kurosawa, H.2    Inaba, T.3    Meltzer, P.S.4    Look, A.T.5
  • 33
    • 0028231938 scopus 로고
    • Fusion with E2A converts the Pbx1 homeodomain protein into a constitutive transcriptional activator in human leukemias carrying the t(1;19) translocation
    • Lu Q, Wright DD, Kamps MP: Fusion with E2A converts the Pbx1 homeodomain protein into a constitutive transcriptional activator in human leukemias carrying the t(1;19) translocation. Mol Cell Biol 14:3938, 1994
    • (1994) Mol Cell Biol , vol.14 , pp. 3938
    • Lu, Q.1    Wright, D.D.2    Kamps, M.P.3
  • 35
    • 0028148938 scopus 로고
    • The helix-loop-helix gene E2A is required for B cell formation
    • Zhuang Y, Soriano P, Weintraub H: The helix-loop-helix gene E2A is required for B cell formation. Cell 79:875, 1994
    • (1994) Cell , vol.79 , pp. 875
    • Zhuang, Y.1    Soriano, P.2    Weintraub, H.3
  • 37
    • 0031029142 scopus 로고    scopus 로고
    • Cell transformation mediated by homodimeric E2A-HLF transcription factor
    • Inukai T, Inaba T, Yoshihara T, Look AT: Cell transformation mediated by homodimeric E2A-HLF transcription factor. Mol Cell Biol 17:1413, 1997
    • (1997) Mol Cell Biol , vol.17 , pp. 1413
    • Inukai, T.1    Inaba, T.2    Yoshihara, T.3    Look, A.T.4
  • 38
    • 0028089760 scopus 로고
    • Transformation properties of the E2a-Pbx1 chimeric oncoprotein: Fusion with E2a is essential, but the Pbx1 homeodomain is dispensable
    • Monica K, LeBrun DP, Dedera DA, Brown R, Cleary ML: Transformation properties of the E2a-Pbx1 chimeric oncoprotein: Fusion with E2a is essential, but the Pbx1 homeodomain is dispensable. Mol Cell Biol 14:8304, 1994
    • (1994) Mol Cell Biol , vol.14 , pp. 8304
    • Monica, K.1    LeBrun, D.P.2    Dedera, D.A.3    Brown, R.4    Cleary, M.L.5
  • 39
    • 0030054255 scopus 로고    scopus 로고
    • DNA-binding by oncoprotein E2A-Pbx1 is important for blocking differentiation but dispensable for flbroblast transformation
    • Kamps MP, Wright DD, Lu Q: DNA-binding by oncoprotein E2A-Pbx1 is important for blocking differentiation but dispensable for flbroblast transformation. Oncogene 12:19, 1996
    • (1996) Oncogene , vol.12 , pp. 19
    • Kamps, M.P.1    Wright, D.D.2    Lu, Q.3
  • 40
    • 0025804491 scopus 로고
    • Enhancer-binding activity of the tal-1 oncoprotein in association with the E47/E12 helix-loop-helix proteins
    • Hsu HL, Cheng JT, Chen Q, Baer R: Enhancer-binding activity of the tal-1 oncoprotein in association with the E47/E12 helix-loop-helix proteins. Mol Cell Biol 11:3037, 1991
    • (1991) Mol Cell Biol , vol.11 , pp. 3037
    • Hsu, H.L.1    Cheng, J.T.2    Chen, Q.3    Baer, R.4
  • 41
    • 0028348648 scopus 로고
    • Formation of in vivo complexes between the Tall and E2A polypeptides of leukemic T cells
    • Hsu HL, Wadman I, Baer R: Formation of in vivo complexes between the Tall and E2A polypeptides of leukemic T cells. Proc Natl Acad Sci USA 91:3181, 1994
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 3181
    • Hsu, H.L.1    Wadman, I.2    Baer, R.3
  • 42
    • 0029981648 scopus 로고    scopus 로고
    • Protein dimerization between Lmo2 (Rbtn2) and Tall alters thymocyte development and potentiates T cell tumorigenesis in transgenic mice
    • Larson RC, Lavenir I, Larson TA, Baer R, Warren AJ, Wadman I, Nottage K, Rabbitts TH: Protein dimerization between Lmo2 (Rbtn2) and Tall alters thymocyte development and potentiates T cell tumorigenesis in transgenic mice. EMBO J 15:1021, 1996
    • (1996) EMBO J , vol.15 , pp. 1021
    • Larson, R.C.1    Lavenir, I.2    Larson, T.A.3    Baer, R.4    Warren, A.J.5    Wadman, I.6    Nottage, K.7    Rabbitts, T.H.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.