Antagonistic role of E4BP4 and PAR proteins in the circadian oscillatory mechanism

Genes and Development

Volumn 15, Issue 8, 2001, Pages 995-1006

  Mitsui, Shigeru ^a   Yamaguchi, Shun ^a   Matsuo, Takuya ^a,b   Ishida, Yoshiki ^a   Okamura, Hitoshi ^a  

^a KOBE UNIVERSITY   (Japan)

^b YAMAGUCHI UNIVERSITY   (Japan)

Author keywords

Active repressor; Basic leucine zipper transcription factor; Circadian rhythm; E4BP4; PAR domain; Suprachiasmatic nucleus

Indexed keywords

COMPLEMENTARY DNA; DNA BINDING PROTEIN; LEUCINE ZIPPER PROTEIN; MESSENGER RNA; TRANSCRIPTION FACTOR;

ANIMAL EXPERIMENT; ARTICLE; CIRCADIAN RHYTHM; DNA BINDING; GENE EXPRESSION; GENETIC TRANSCRIPTION; IMMUNOCYTOCHEMISTRY; IN SITU HYBRIDIZATION; LIVER; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OSCILLATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; SUPRACHIASMATIC NUCLEUS;

ANIMALS; BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS; BLOTTING, NORTHERN; BLOTTING, WESTERN; CELL NUCLEUS; CIRCADIAN RHYTHM; DIMERIZATION; DNA-BINDING PROTEINS; G-BOX BINDING FACTORS; GENETIC VECTORS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; KINETICS; LEUCINE ZIPPERS; LIVER; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED BALB C; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; NEOPLASM PROTEINS; PLASMIDS; PROTEIN BINDING; PROTEIN BIOSYNTHESIS; PROTEIN STRUCTURE, TERTIARY; PROTEINS; RNA, MESSENGER; TIME FACTORS; TISSUE DISTRIBUTION; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

ANIMALIA; ERAGROSTIS TEF; MAMMALIA; RICKETTSIA SP. PAR;

EID: 0035871311     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.873501     Document Type: Article

References (44)

1. Cycling vrille expression is required for a functional Drosophila clock
2. Transcriptional repression by a novel member of the bZIP family of transcription factors
3. Transcriptional repression by the human bZIP factor E4BP4: Definition of a minimal repression domain
4. TEF, a transcription factor expressed specifically in the anterior pituitary during embryogenesis, defines a new class of leucine zipper proteins
5. Molecular bases for circadian clocks
6. The rat hepatic leukemia factor (HLF) gene encodes two transcriptional activators with distinct circadian rhythms, tissue distributions and target preferences
7. DNA-binding specificity of PAR and C/EBP leucine zipper proteins: A single amino acid substitution in the C/EBP DNA-binding domain confers PAR-like specificity to C/EBP
8. Analysis of clock proteins in mouse SCN demonstrates phylogenetic divergence of the circadian clockwork and resetting mechanisms
9. The two PAR leucine zipper proteins, TEF and DBP, display similar circadian and tissue-specific expression, but have different target promoter preferences
10. Role of the CLOCK protein in the mammalian circadian mechanism
11. The vrille gene of Drosophila is a maternal enhancer of decapentaplegic and encodes a new member of the bZIP family of transcription factors
12. Light-independent role of CRY1 and CRY2 in the mammalian circadian clock
13. PAS is a dimerization domain common to Drosophila period and several transcription factors
14. The proto-oncogene HLF and the related basic leucine zipper protein TEF display highly similar DNA-binding and transcriptional regulatory properties
15. Pivotal role for the NFIL3/E4BP4 transcription factor in interleukin 3-mediated survival of pro-B lymphocytes
16. The current state and problems of circadian clock studies in cyanobacteria
17. A molecular mechanism regulating rhythmic output from the suprachiasmatic circadian clock
18. Molecular genetics of circadian rhythms in mammals
19. Characterization of photolyase/blue-light receptor homologs in mouse and human cells
20. mCRY1 and mCRY2 are essential components of the negative limb of the circadian clock feedback loop
21. Two distinct interleukin-3-mediated signal pathways, Ras-NFIL3 (E4BP4) and Bcl-xL, regulate the survival of murine pro-B lymphocytes
22. D-site binding protein transactivation requires the proline- and acid-rich domain and involves the coactivator p300
23. Circadian expression of the steroid 15 α-hydroxylase (Cyp2a4) and coumarin 7-hydroxylase (Cyp2a5) genes in mouse liver is regulated by the PAR leucine zipper transcription factor DBP
24. Protein-protein interaction via PAS domains: Role of the PAS domain in positive and negative regulation of the bHLH/PAS dioxin receptor-Arnt transcription factor complex
25. The DBP gene is expressed according to a circadian rhythm in the suprachiasmatic nucleus and influences circadian behavior
26. Photic induction of mPer1 and mPer2 in Cry-deficient mice lacking a biological clock
27. CLOCK, an essential pacemaker component, controls expression of the circadian transcription factor DBP
28. Transcriptional control: Rheostat converted to on/off switch
29. Interacting molecular loops in the mammalian circadian clock
30. Light-induced resetting of a mammalian circadian clock is associated with rapid induction of the mPer1 transcript
31. A new mammalian period gene predominantly expressed in the suprachiasmatic nucleus
32. A light-independent oscillatory gene mPer3 in mouse SCN and OVLT
33. Circadian oscillation of a mammalian homologue of the Drosophila period gene
34. Similarity among the Drosophila (6-4) photolyase, a human photolyase homolog, and the DNA photolyase-blue-light photoreceptor family
35. Mammalian Cry1 and Cry2 are essential for maintenance of circadian rhythms
36. Dimerization and nuclear entry of mPER proteins in mammalian cells
37. Regional expression and regulation of alternative forms of mRNAs derived from two distinct transcription initiation sites of the rat mGluR5 gene
38. The 5′ upstream region of mPer1 gene contains two promoters and is responsible for circadian oscillation
39. Role of DBP in the circadian oscillatory mechanism
40. Distribution and circadian expression of dbp in SCN and extra-SCN areas in the mouse brain
41. Life's 24-hour clock: Molecular control of circadian rhythms in animal cells
42. Molecular cloning and characterization of NF-IL3A, a transcriptional activator of the human interleukin-3 promoter
43. The mPer2 gene encodes a functional component of the mammalian circadian clock
44. Three period homologs in mammals: Differential light responses in the suprachiasmatic circadian clock and oscillating transcripts outside of brain