Mammalian clock gene Cryptochrome regulates arthritis via proinflammatory cytokine TNF-α

Journal of Immunology

Volumn 184, Issue 3, 2010, Pages 1560-1565

  Hashiramoto, Akira ^a,b,c   Yamane, Takashi ^b   Tsumiyama, Ken ^a   Yoshida, Kohsuke ^a   Komai, Koichiro ^a   Yamada, Hiroyuki ^d   Yamazaki, Fumiyoshi ^d   Doi, Masao ^d   Okamura, Hitoshi ^d   Shiozawa, Shunichi ^a,b,c  

^a KOBE UNIVERSITY   (Japan)

^b KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c KOBE UNIVERSITY HOSPITAL   (Japan)

^d KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CD69 ANTIGEN; CRYPTOCHROME 1; CRYPTOCHROME 2; INTERLEUKIN 1BETA; INTERLEUKIN 6; PROTEIN BMAL1; STROMELYSIN; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA ANTIBODY; AUTACOID; CRY1 PROTEIN, MOUSE; CRY2 PROTEIN, MOUSE; CRYPTOCHROME; TRANSCRIPTION FACTOR CLOCK;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTHRITIS; ARTICLE; CD3+ T LYMPHOCYTE; CELL NUCLEUS; CIRCADIAN RHYTHM; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE COURSE; DISEASE EXACERBATION; DISEASE SEVERITY; EMBRYO; FEMALE; FIBROBLAST; GENE ACTIVATION; GENE DELETION; GENE EXPRESSION; JOINT SWELLING; LYMPHOCYTE COUNT; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPLEEN CELL; SYNOVIOCYTE; UPREGULATION; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; GENETICS; IMMUNOLOGY; MOUSE MUTANT; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; ARTHRITIS, EXPERIMENTAL; CIRCADIAN RHYTHM; CLOCK PROTEINS; CRYPTOCHROMES; FEMALE; INFLAMMATION MEDIATORS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 77949333592     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0903284     Document Type: Article

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