-
1
-
-
0026775958
-
Free radical theory of aging
-
Harman D. Free radical theory of aging. Mutat Res 1992; 275 (3-6): 257-66.
-
(1992)
Mutat Res
, vol.275
, Issue.3-6
, pp. 257-266
-
-
Harman, D.1
-
2
-
-
0036710886
-
Mechanisms of aging: An appraisal of the oxidative stress hypothesis
-
Sohal RS, Mockett RJ, Orr WC. Mechanisms of aging: an appraisal of the oxidative stress hypothesis. Free Rad Biol Med 2002; 33 (5): 575-86.
-
(2002)
Free Rad Biol Med
, vol.33
, Issue.5
, pp. 575-586
-
-
Sohal, R.S.1
Mockett, R.J.2
Orr, W.C.3
-
3
-
-
0037218826
-
The Biology of aging
-
Troen BR. The Biology of aging. Mt Sinai J Med 2003; 70(1): 3-22.
-
(2003)
Mt Sinai J Med
, vol.70
, Issue.1
, pp. 3-22
-
-
Troen, B.R.1
-
4
-
-
0031845040
-
Oxidative damage in the central nervous system: Protection by melatonin
-
Reiter RJ. Oxidative damage in the central nervous system: protection by melatonin. Prog Neurobiol 1998; 56: 359-84.
-
(1998)
Prog Neurobiol
, vol.56
, pp. 359-384
-
-
Reiter, R.J.1
-
5
-
-
0033001521
-
The oxidant/antioxidant network: Role of melatonin
-
Reiter RJ, Tan DX, Cabrera J, D'Arpa D, Sainz RM, Mayo JC, Ramos S. The oxidant/antioxidant network: role of melatonin. Biol Signals Recept 1999; 8: 56-63.
-
(1999)
Biol Signals Recept
, vol.8
, pp. 56-63
-
-
Reiter, R.J.1
Tan, D.X.2
Cabrera, J.3
D'Arpa, D.4
Sainz, R.M.5
Mayo, J.C.6
Ramos, S.7
-
6
-
-
0029984062
-
Antioxidant and redox regulation of gene transcription
-
Sen CK, Packer L. Antioxidant and redox regulation of gene transcription. FASEB J 1996; 10: 709-20.
-
(1996)
FASEB J
, vol.10
, pp. 709-720
-
-
Sen, C.K.1
Packer, L.2
-
7
-
-
0032527705
-
The cellular response to oxidative stress: Influences of mitogen-activated protein kinase signaling pathways on cell survival
-
Wang X, Martindale JL. The cellular response to oxidative stress: influences of mitogen-activated protein kinase signaling pathways on cell survival. Biochem J 1998; 333: 291-300.
-
(1998)
Biochem J
, vol.333
, pp. 291-300
-
-
Wang, X.1
Martindale, J.L.2
-
8
-
-
0037432615
-
Multiple pathways of peroxynitrite cytotoxicity
-
Szabo C. Multiple pathways of peroxynitrite cytotoxicity. Toxicol Lett 2003; 140-141:105-12.
-
(2003)
Toxicol Lett
, vol.140-141
, pp. 105-112
-
-
Szabo, C.1
-
9
-
-
0033945846
-
Mitochondrial oxidative stress plays a key role in aging and apoptosis
-
Sastre J, Pallardo FV, Vina J. Mitochondrial oxidative stress plays a key role in aging and apoptosis. IUBMB Life 2000; 45: 427-35.
-
(2000)
IUBMB Life
, vol.45
, pp. 427-435
-
-
Sastre, J.1
Pallardo, F.V.2
Vina, J.3
-
10
-
-
4243550127
-
Heme oxyganase/carbon monoxide signaling pathways: Regulation and functional significance
-
Ryter SW, Otterbein LE, Morse D, Choi AM. Heme oxyganase/carbon monoxide signaling pathways: regulation and functional significance. Mol Cell Biochem 2002; 234-235: 249-63.
-
(2002)
Mol Cell Biochem
, vol.234-235
, pp. 249-263
-
-
Ryter, S.W.1
Otterbein, L.E.2
Morse, D.3
Choi, A.M.4
-
11
-
-
0037653659
-
Gender difference in glutathione metabolism during aging in mice
-
Wang H, Liu H, Liu RM. Gender difference in glutathione metabolism during aging in mice. Exp Gerontol 2003; 38(5): 507-17.
-
(2003)
Exp Gerontol
, vol.38
, Issue.5
, pp. 507-517
-
-
Wang, H.1
Liu, H.2
Liu, R.M.3
-
12
-
-
12144265572
-
Microsomal Glutathione S-transferase 1 in the retinal pigment epithelium: Protection against oxidative stress and a potential role in aging
-
Maeda A, Crabb JW. Microsomal Glutathione S-transferase 1 in the retinal pigment epithelium: Protection against oxidative stress and a potential role in aging. Biochemistry 2005; 44: 480-89.
-
(2005)
Biochemistry
, vol.44
, pp. 480-489
-
-
Maeda, A.1
Crabb, J.W.2
-
14
-
-
0025549551
-
Do hepatocytes age?
-
Schmucker D. Do hepatocytes age? Exp Gerontol 1990; 25:403-12.
-
(1990)
Exp Gerontol
, vol.25
, pp. 403-412
-
-
Schmucker, D.1
-
15
-
-
0031732240
-
Ageing affects anoxia/reoxygenation injury in rat hepatocytes
-
Gasbarrini A, Simoncini M, Di Campli C, et al. Ageing affects anoxia/reoxygenation injury in rat hepatocytes. Scand J Gastroenterol 1998; 33(10): 1107-12.
-
(1998)
Scand J Gastroenterol
, vol.33
, Issue.10
, pp. 1107-1112
-
-
Gasbarrini, A.1
Simoncini, M.2
di Campli, C.3
-
16
-
-
0035871677
-
Effects of ageing on the susceptibility to the toxic effects of Cyclosporin A in rats. Changers in liver glutathione and antioxidant enzymes
-
Palomero J, Galan AI, Munoz ME, et al. Effects of ageing on the susceptibility to the toxic effects of Cyclosporin A in rats. Changers in liver glutathione and antioxidant enzymes. Free Radic Biol Med 2001; 30 (8): 836-45.
-
(2001)
Free Radic Biol Med
, vol.30
, Issue.8
, pp. 836-845
-
-
Palomero, J.1
Galan, A.I.2
Munoz, M.E.3
-
17
-
-
0034564392
-
Melatonin directly scavenges hydrogen peroxide: A potentially new metabolic pathway of melatonin biotransformation
-
Tan DX, Manchester LC, Reiter RJ. Melatonin directly scavenges hydrogen peroxide: a potentially new metabolic pathway of melatonin biotransformation. Free Radic Biol Med 2000; 29: 1177-85.
-
(2000)
Free Radic Biol Med
, vol.29
, pp. 1177-1185
-
-
Tan, D.X.1
Manchester, L.C.2
Reiter, R.J.3
-
18
-
-
0029563204
-
Oxygen radical detoxification process during aging: The functional importance of melatonin
-
Reiter RJ. Oxygen radical detoxification process during aging: the functional importance of melatonin. Aging (Milano) 1995; 7: 340-51.
-
(1995)
Aging (Milano)
, vol.7
, pp. 340-351
-
-
Reiter, R.J.1
-
19
-
-
0030914428
-
Pharmacological actions of melatonin in oxygen radical pathophysiology
-
Reiter R, Tang L, Garcia JJ. Pharmacological actions of melatonin in oxygen radical pathophysiology. Life Sci 1997; 60: 2255-71.
-
(1997)
Life Sci
, vol.60
, pp. 2255-2271
-
-
Reiter, R.1
Tang, L.2
Garcia, J.J.3
-
20
-
-
0027725205
-
Distribution of melatonin in mammalian tissues: The importance of nuclear versus cytosolic localization
-
Menendez-Pelaez A, Reiter RJ. Distribution of melatonin in mammalian tissues: the importance of nuclear versus cytosolic localization. J Pineal Res 1993; 15: 59-67.
-
(1993)
J Pineal Res
, vol.15
, pp. 59-67
-
-
Menendez-Pelaez, A.1
Reiter, R.J.2
-
21
-
-
0035754146
-
Biochemical reactivity of melatonin with reactive oxygen and nitrogen species
-
Reiter RJ, Tan DX, Manchester LC, Qi W. Biochemical reactivity of melatonin with reactive oxygen and nitrogen species. Cell Biochem Biophys 2001; 34:237-56.
-
(2001)
Cell Biochem Biophys
, vol.34
, pp. 237-256
-
-
Reiter, R.J.1
Tan, D.X.2
Manchester, L.C.3
Qi, W.4
-
22
-
-
1642562820
-
Regulation of antioxidant enzymes: A significant role for melatonin
-
Rodrigues C, Mayo JC, Sainz RM, et al. Regulation of antioxidant enzymes: a significant role for melatonin. J. Pineal Res. 2004; 36 (1): 1-9.
-
(2004)
J. Pineal Res
, vol.36
, Issue.1
, pp. 1-9
-
-
Rodrigues, C.1
Mayo, J.C.2
Sainz, R.M.3
-
23
-
-
0033817812
-
Free radical generation and oxidative stress with aging an dexercise: Differential effects in the myocardium and liver
-
Bejma J, Ramires P, Ji LL. Free radical generation and oxidative stress with aging an dexercise: differential effects in the myocardium and liver. Acta Physiol Scand 2000; 169 (4): 343-51.
-
(2000)
Acta Physiol Scand
, vol.169
, Issue.4
, pp. 343-351
-
-
Bejma, J.1
Ramires, P.2
Ji, L.L.3
-
24
-
-
0034906869
-
Effect of dietary restriction on agerelated increase of liver-related increase of liver susceptibility to peroxidation
-
Jeon TI, Lim BO, Yu BP. Effect of dietary restriction on agerelated increase of liver-related increase of liver susceptibility to peroxidation. Lipids. 2001; 36 (6): 589-93.
-
(2001)
Lipids
, vol.36
, Issue.6
, pp. 589-593
-
-
Jeon, T.I.1
Lim, B.O.2
Yu, B.P.3
-
25
-
-
0242333261
-
Melatonin protects against pro-oxidant enzymes and reduces lipid peroxidation in distinct membranes induced by the hydroxyl and ascorbyl radicals and by peroxynitrite
-
Teixeira A, Morfim MP, De Cordova CA. et al. Melatonin protects against pro-oxidant enzymes and reduces lipid peroxidation in distinct membranes induced by the hydroxyl and ascorbyl radicals and by peroxynitrite. J Pineal Res. 2003, 35: 262-68.
-
(2003)
J Pineal Res
, vol.35
, pp. 262-268
-
-
Teixeira, A.1
Morfim, M.P.2
de Cordova, C.A.3
-
26
-
-
0034988397
-
Oxidative damage to mitochondria and aging
-
Van Remmen H, Richardson A. Oxidative damage to mitochondria and aging. Exp Gerontol 2001; 36 (7): 957-68.
-
(2001)
Exp Gerontol
, vol.36
, Issue.7
, pp. 957-968
-
-
van Remmen, H.1
Richardson, A.2
-
28
-
-
0036172464
-
Melatonin increases the activity of the oxidative phosphorylation enzymes and the production of ATP in rat brain and liver mitochondria
-
Martin M, Macias M, Leonm J, et al. Melatonin increases the activity of the oxidative phosphorylation enzymes and the production of ATP in rat brain and liver mitochondria. Int J Biochem Cell Biol 2002; 34: 348-57.
-
(2002)
Int J Biochem Cell Biol
, vol.34
, pp. 348-357
-
-
Martin, M.1
Macias, M.2
Leonm, J.3
-
29
-
-
0038661151
-
Melatonin counteracts lipopolysaccharide-induced expression and activity of mitochondrial nitric oxide synthase in rats
-
Escames G, Leon J, Macias M, et al. Melatonin counteracts lipopolysaccharide-induced expression and activity of mitochondrial nitric oxide synthase in rats. FASEB J. 2003; 17: 932-24.
-
(2003)
FASEB J
, vol.17
, pp. 932-1024
-
-
Escames, G.1
Leon, J.2
Macias, M.3
-
30
-
-
0036252301
-
Melatonin reduces oxidative damage of neural lipids and proteins in senescence-accelerated mouse
-
Okatani Y, Wakatsuki A, Reiter RJ, et al. Melatonin reduces oxidative damage of neural lipids and proteins in senescence-accelerated mouse. Neurobiol Aging 2002; 23: 639-44.
-
(2002)
Neurobiol Aging
, vol.23
, pp. 639-644
-
-
Okatani, Y.1
Wakatsuki, A.2
Reiter, R.J.3
-
31
-
-
0038054054
-
Protective effect of melatonin against mitochondrial injury induced by ischemia and reperfusion of rat liver
-
Okatani Y, Wakatsuki A, Reiter RJ, et al. Protective effect of melatonin against mitochondrial injury induced by ischemia and reperfusion of rat liver. Eur J Pharmacol 2003; 469: 145-52.
-
(2003)
Eur J Pharmacol
, vol.469
, pp. 145-152
-
-
Okatani, Y.1
Wakatsuki, A.2
Reiter, R.J.3
-
32
-
-
0036425007
-
Protective effect of melatonin in carrageenan-induced acute local inflammation
-
Bilici D, Akpinar E, Kiziltunc A. Protective effect of melatonin in carrageenan-induced acute local inflammation. Pharmacol Res 2002; 46: 133-39.
-
(2002)
Pharmacol Res
, vol.46
, pp. 133-139
-
-
Bilici, D.1
Akpinar, E.2
Kiziltunc, A.3
-
33
-
-
0344131940
-
Melatonin inhibits expression of the inducible NO synthase II in liver and lung and prevents endotoxemia in lipopolysaccharide-induced multiple organ dysfunction syndrome in rats
-
Crespo E, Macias M, Pozo D. et al. Melatonin inhibits expression of the inducible NO synthase II in liver and lung and prevents endotoxemia in lipopolysaccharide-induced multiple organ dysfunction syndrome in rats. FASEB J 1999; 13: 1537-46.
-
(1999)
FASEB J
, vol.13
, pp. 1537-1546
-
-
Crespo, E.1
Macias, M.2
Pozo, D.3
-
34
-
-
0346059342
-
Melatonin inhibits nuclear factor kappa B activation and oxidative stress and protects against thioacetamide induced liver damage in rats
-
Bruck R, Aeed H, Avni Y. et al. Melatonin inhibits nuclear factor kappa B activation and oxidative stress and protects against thioacetamide induced liver damage in rats. J Hepatol 2004; 40: 86-93.
-
(2004)
J Hepatol
, vol.40
, pp. 86-93
-
-
Bruck, R.1
Aeed, H.2
Avni, Y.3
-
35
-
-
0035949667
-
Snyder SH Neural roles for heme oxygenase: Contrast to nitric oxide synthase
-
Barañano DE, Snyder SH Neural roles for heme oxygenase: contrast to nitric oxide synthase. Proc Natl Acad Sci 2001; 98: 10996-1002.
-
(2001)
Proc Natl Acad Sci
, vol.98
, pp. 10996-11002
-
-
Barañano, D.E.1
-
36
-
-
0034071424
-
Carbon monoxide has antiinflammatory effects involving the mitogen-activated protein kinase pathway
-
Otterbein LE, Bach FH, Alam J. et al. Carbon monoxide has antiinflammatory effects involving the mitogen-activated protein kinase pathway. Nat Med 2000; 6: 422-28.
-
(2000)
Nat Med
, vol.6
, pp. 422-428
-
-
Otterbein, L.E.1
Bach, F.H.2
Alam, J.3
-
37
-
-
0035834304
-
Modulation of heme oxagenase in tissue injury and its implication in protection against gastrointestinal diseases
-
Guo X, Shin VY, Cho CH. Modulation of heme oxagenase in tissue injury and its implication in protection against gastrointestinal diseases. Life Sci 2001; 69: 3113-19.
-
(2001)
Life Sci
, vol.69
, pp. 3113-3119
-
-
Guo, X.1
Shin, V.Y.2
Cho, C.H.3
-
38
-
-
0037131586
-
Melatonin prevents focal rat cerebellum injury as assessed by induction of heat shock protein (HO-1) following subarachnoid injections of lysed blood
-
Martínez-Cruz F, Espinar A, Pozo D, et al. Melatonin prevents focal rat cerebellum injury as assessed by induction of heat shock protein (HO-1) following subarachnoid injections of lysed blood. Neurosci Lett 2002; 331: 208-10.
-
(2002)
Neurosci Lett
, vol.331
, pp. 208-210
-
-
Martínez-Cruz, F.1
Espinar, A.2
Pozo, D.3
-
39
-
-
1442282910
-
Age-related changes in the activity of antioxidant and redox enzymes in rats
-
Kim HG, Hong SM, Kim SJ. Age-related changes in the activity of antioxidant and redox enzymes in rats. Mol Cells 2003; 16: 278-84.
-
(2003)
Mol Cells
, vol.16
, pp. 278-284
-
-
Kim, H.G.1
Hong, S.M.2
Kim, S.J.3
-
40
-
-
0022259872
-
Interaction of glutathione peroxidase by superoxide radical
-
Blum J, Fridovich I. Interaction of glutathione peroxidase by superoxide radical. Arch.Bioche. Biophys 1985; 280: 500-8.
-
(1985)
Arch.Bioche. Biophys
, vol.280
, pp. 500-508
-
-
Blum, J.1
Fridovich, I.2
-
41
-
-
0037621502
-
Park YS Oxidative stress caused by inactivation of glutathione peroxidase and adaptive responses
-
Miyamoto Y, Koh YH, Park YS Oxidative stress caused by inactivation of glutathione peroxidase and adaptive responses. Biol Chem. 2003; 384(4): 567-74.
-
(2003)
Biol Chem
, vol.384
, Issue.4
, pp. 567-574
-
-
Miyamoto, Y.1
Koh, Y.H.2
-
42
-
-
0033896832
-
2-induced cell induced death via coordinated regulation of stress kinases
-
2-induced cell induced death via coordinated regulation of stress kinases. Cancer Res. 2000; 60: 4053-57.
-
(2000)
Cancer Res
, vol.60
, pp. 4053-4057
-
-
Yin, Z.1
Ivanov, V.N.2
Habelsah, H.3
-
43
-
-
21644483188
-
Effect of rh GH on age related hepatocyte changes in old male and female
-
Endocrine
-
Castillo C, Salazar V, Ariznavarreta C, et al. Effect of rh GH on age related hepatocyte changes in old male and female Wistar rats. 2004; Endocrine 25: 33-9.
-
(2004)
Wistar Rats
, vol.25
, pp. 33-39
-
-
Castillo, C.1
Salazar, V.2
Ariznavarreta, C.3
-
44
-
-
0030581151
-
Induction of apoptotic program in cell-free extracts: Requirement for dATP and cytochrome c
-
Liu X, Kim CN, Yang J, Jemmerson R, Wang X. Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell 1996; 86: 147-57.
-
(1996)
Cell
, vol.86
, pp. 147-157
-
-
Liu, X.1
Kim, C.N.2
Yang, J.3
Jemmerson, R.4
Wang, X.5
-
45
-
-
0030715323
-
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
-
Li P, Nijhawan D, Budihardjo I, Srinivasula SM, Ahmad M, Alnemri ES and Wang X. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 1997; 91: 479-89.
-
(1997)
Cell
, vol.91
, pp. 479-489
-
-
Li, P.1
Nijhawan, D.2
Budihardjo, I.3
Srinivasula, S.M.4
Ahmad, M.5
Alnemri, E.S.6
Wang, X.7
-
46
-
-
0025123554
-
The Framingham Disability Study: Relationship of various coronary heart disease manifestations to disability in older persons living in the community
-
Pinsky JL, Jette AM, Branch LG, Kannel WB, Feinleib M. The Framingham Disability Study: relationship of various coronary heart disease manifestations to disability in older persons living in the community. Am. J Public Health 1990; 80: 1363-67.
-
(1990)
Am. J Public Health
, vol.80
, pp. 1363-1367
-
-
Pinsky, J.L.1
Jette, A.M.2
Branch, L.G.3
Kannel, W.B.4
Feinleib, M.5
-
47
-
-
0037083794
-
Clinical characteristics of coronary heart disease in women: Emphasis on gender differences
-
Wenger NK. Clinical characteristics of coronary heart disease in women: emphasis on gender differences. Cardiovasc Res 2002; 53: 558-67.
-
(2002)
Cardiovasc Res
, vol.53
, pp. 558-567
-
-
Wenger, N.K.1
-
48
-
-
0026562278
-
Epidemiology of the menopause
-
Khaw KT. Epidemiology of the menopause. Br Med Bull 1992; 48: 249-61.
-
(1992)
Br Med Bull
, vol.48
, pp. 249-261
-
-
Khaw, K.T.1
-
49
-
-
0033305551
-
Neuroendocrine influences and repercussions of the menopause
-
Wise PM, Smith MJ, Dubal DB, Wilson ME, Krajnak KM, Rosewell KL. Neuroendocrine influences and repercussions of the menopause. Endocr Rev 1999; 20: 243-48.
-
(1999)
Endocr Rev
, vol.20
, pp. 243-248
-
-
Wise, P.M.1
Smith, M.J.2
Dubal, D.B.3
Wilson, M.E.4
Krajnak, K.M.5
Rosewell, K.L.6
-
51
-
-
0021949448
-
Glutathione peroxidase and reductase activities in the aging mouse
-
Hazelton GA and Lang CA. Glutathione peroxidase and reductase activities in the aging mouse. Mech Ageing Dev 1985; 29: 71-81.
-
(1985)
Mech Ageing Dev
, vol.29
, pp. 71-81
-
-
Hazelton, G.A.1
Lang, C.A.2
-
52
-
-
23844513201
-
Effect of growth hormone and estrogen administration on hepatocyte alterations in old ovariectomized female wistar rats
-
Castillo C, Salazar V, Ariznavarreta C, Vara E, Tresguerres JAF. Effect of growth hormone and estrogen administration on hepatocyte alterations in old ovariectomized female wistar rats. Endocrine 2005; 26: 11-8.
-
(2005)
Endocrine
, vol.26
, pp. 11-18
-
-
Castillo, C.1
Salazar, V.2
Ariznavarreta, C.3
Vara, E.4
Tresguerres, J.A.F.5
-
53
-
-
19544366297
-
Oxidative stress induces vascular heme oxygenase-1 expression in ovariectomized rats
-
Lee YM, Cheng PY, Hong SF, Chen SY, Lam KK, Sheu JR, Yen MH. Oxidative stress induces vascular heme oxygenase-1 expression in ovariectomized rats. Free Radic Biol Med 2005; 39 (1): 108-17.
-
(2005)
Free Radic Biol Med
, vol.39
, Issue.1
, pp. 108-117
-
-
Lee, Y.M.1
Cheng, P.Y.2
Hong, S.F.3
Chen, S.Y.4
Lam, K.K.5
Sheu, J.R.6
Yen, M.H.7
-
54
-
-
33644845068
-
The effect of oestradiol and neta on immunohistochemical attaining of iNOS and eNOS in coronary arteries of ovariectomized rats
-
Koyuncu FM, Ozbiling K, Kuscu NK, Inan S, Vatansever S, Ceylan E. The effect of oestradiol and neta on immunohistochemical attaining of iNOS and eNOS in coronary arteries of ovariectomized rats. Histol Histopathol 2006; 21 (4): 367-71.
-
(2006)
Histol Histopathol
, vol.21
, Issue.4
, pp. 367-371
-
-
Koyuncu, F.M.1
Ozbiling, K.2
Kuscu, N.K.3
Inan, S.4
Vatansever, S.5
Ceylan, E.6
-
55
-
-
0000939207
-
Natural history and mechanisms of reproductive aging in humans, laboratory rodents and other selected vertebrates
-
a ed., Raven Press, NY
-
Vom Saal FS, Finch CE, Nelson JF. Natural history and mechanisms of reproductive aging in humans, laboratory rodents and other selected vertebrates. In: Knobil, E., Neill, J.D. (Eds.), The physiology of reproduction, 2a ed., Raven Press, NY, 1994; pp. 1213-314.
-
(1994)
The Physiology of Reproduction
, pp. 1213-1314
-
-
Vom, S.F.S.1
Finch, C.E.2
Nelson, J.F.3
-
56
-
-
0142151379
-
Mitochondrial theory of aging: Importance to explain why females live longer than males
-
Vina J, Sastre J, Pallardo F, Borras C. Mitochondrial theory of aging: importance to explain why females live longer than males. Antioxid Redox Signal 2003; 5: 549-56.
-
(2003)
Antioxid Redox Signal
, vol.5
, pp. 549-556
-
-
Vina, J.1
Sastre, J.2
Pallardo, F.3
Borras, C.4
-
57
-
-
22844445559
-
Effect of melatonin administration on parameters related to oxidative damage in hepatocytes isolated from old Wistar rats
-
Castillo C, Salazar V, Ariznavarreta C, et al. Effect of melatonin administration on parameters related to oxidative damage in hepatocytes isolated from old Wistar rats. J. Pineal Res 2005; 38: 240-46.
-
(2005)
J. Pineal Res
, vol.38
, pp. 240-246
-
-
Castillo, C.1
Salazar, V.2
Ariznavarreta, C.3
-
58
-
-
0034985577
-
The aging liver: Consequences for drug treatment in old age
-
Zeeh J. The aging liver: consequences for drug treatment in old age. Arch Gerontol Geriatr 2001; 32: 255-63.
-
(2001)
Arch Gerontol Geriatr
, vol.32
, pp. 255-263
-
-
Zeeh, J.1
-
59
-
-
0035845492
-
Genomic profiling of short-and long-term caloric restriction effects in the liver of aging mice
-
Cao SX, Dhahbi JM, Mote PL, Spindler SR. Genomic profiling of short-and long-term caloric restriction effects in the liver of aging mice. Proc Natl Acad Sci USA 2001; 98: 10630-35.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 10630-10635
-
-
Cao, S.X.1
Dhahbi, J.M.2
Mote, P.L.3
Spindler, S.R.4
-
60
-
-
0027480925
-
Kupffer cells: Their activation and role in animal models of liver injury and human liver disease
-
Winwood PJ, Arthur MJP. Kupffer cells: their activation and role in animal models of liver injury and human liver disease. Semin Liver Dis 1993; 13: 50-9.
-
(1993)
Semin Liver Dis
, vol.13
, pp. 50-59
-
-
Winwood, P.J.1
Arthur, M.J.P.2
-
61
-
-
0033060611
-
Cytokine regulation of hepatic stellate cells in liver fibrosis
-
Tsukamoto H. Cytokine regulation of hepatic stellate cells in liver fibrosis. Alcoholism. Clin Exp Res 1999; 23: 911-6.
-
(1999)
Alcoholism. Clin Exp Res
, vol.23
, pp. 911-916
-
-
Tsukamoto, H.1
-
62
-
-
0026734847
-
Stimulation of the nitric oxide pathway in human hepatocytes by cytokines and endotoxin
-
Nussler AK, Disilvio M, Billiar TR, et al. Stimulation of the nitric oxide pathway in human hepatocytes by cytokines and endotoxin. J Exp Med 1992; 176: 261-4.
-
(1992)
J Exp Med
, vol.176
, pp. 261-264
-
-
Nussler, A.K.1
Disilvio, M.2
Billiar, T.R.3
-
63
-
-
0031862076
-
Melatonin inhibits expression of the inducible isoform of nitric oxide synthase in murine macrophages: Role of inhibition of NFkappaB activation
-
Gilad E, Wong HR, Zingarelli B, et al. Melatonin inhibits expression of the inducible isoform of nitric oxide synthase in murine macrophages: role of inhibition of NFkappaB activation. FASEB J 1998; 12: 685-93.
-
(1998)
FASEB J
, vol.12
, pp. 685-693
-
-
Gilad, E.1
Wong, H.R.2
Zingarelli, B.3
-
64
-
-
0035350773
-
Melatonin enhances Th-2 cell mediated immune response: Lack of sensitivity to reversal by naltrexone or benzodiazepine receptor antagonists
-
Raghavendra V, Singh V, Kulkarni SK, Agrewala JN. Melatonin enhances Th-2 cell mediated immune response: lack of sensitivity to reversal by naltrexone or benzodiazepine receptor antagonists. Mol Cell Biochem 2001; 221: 57-62.
-
(2001)
Mol Cell Biochem
, vol.221
, pp. 57-62
-
-
Raghavendra, V.1
Singh, V.2
Kulkarni, S.K.3
Agrewala, J.N.4
-
65
-
-
0035087432
-
Melatonin prevents endotoxininduced circulatory failure in rats
-
Wu CC, Chiao CW, Hsiao G, et al. Melatonin prevents endotoxininduced circulatory failure in rats. J Pineal Res 2001; 30:147-56.
-
(2001)
J Pineal Res
, vol.30
, pp. 147-156
-
-
Wu, C.C.1
Chiao, C.W.2
Hsiao, G.3
-
66
-
-
0032847560
-
Senescence-accelerated mouse (SAM): A biogerontological resource in aging research
-
Takeda T. Senescence-accelerated mouse (SAM): a biogerontological resource in aging research. Neurobiol Aging 1999; 20: 105-10.
-
(1999)
Neurobiol Aging
, vol.20
, pp. 105-110
-
-
Takeda, T.1
-
67
-
-
0032078031
-
Difference between senescence -accelerated prone and resistant mice in response to insulin in the heart
-
Kurokawa T, Ozaki N, Ishibashi S. Difference between senescence -accelerated prone and resistant mice in response to insulin in the heart. Mech Ageing Dev 1998; 102: 25-32.
-
(1998)
Mech Ageing Dev
, vol.102
, pp. 25-32
-
-
Kurokawa, T.1
Ozaki, N.2
Ishibashi, S.3
-
68
-
-
34147199638
-
Chronic administration of melatonin reduces cerebral injury biomarkers in SAMP8
-
Gutierrez-Cuesta J, Sureda FX, Romeu M, Canudas AM, Caballero B, Coto-Montes A, Camins A and Pallàs M. Chronic administration of melatonin reduces cerebral injury biomarkers in SAMP8. J Pineal Res 2007; 42: 394-402.
-
(2007)
J Pineal Res
, vol.42
, pp. 394-402
-
-
Gutierrez-Cuesta, J.1
Sureda, F.X.2
Romeu, M.3
Canudas, A.M.4
Caballero, B.5
Coto-Montes, A.6
Camins, A.7
Pallàs, M.8
-
69
-
-
0036051068
-
Cardiovascular ageing in health sets the stage for cardiovascular disease
-
Lakatta EG. Cardiovascular ageing in health sets the stage for cardiovascular disease. Heart Lung Circ 2002; 11: 76-91.
-
(2002)
Heart Lung Circ
, vol.11
, pp. 76-91
-
-
Lakatta, E.G.1
-
70
-
-
22144452590
-
Aging induces cardiac diastolic dysfunction, oxidative stress, accumulation of advanced glycation endproducts and protein modification
-
Li SY, Du M, Dolence EK, et al. Aging induces cardiac diastolic dysfunction, oxidative stress, accumulation of advanced glycation endproducts and protein modification. Aging Cell 2005; 4: 57-64.
-
(2005)
Aging Cell
, vol.4
, pp. 57-64
-
-
Li, S.Y.1
Du, M.2
Dolence, E.K.3
-
71
-
-
9344256749
-
Mechanisms of aging-induced impairment of endothelium dependent relaxation: Role of tetrahydrobiopterin
-
Blackwell KA, Sorenson JP, Richardson DM, Smith LA, Suda O, Nath K Katusic ZS. Mechanisms of aging-induced impairment of endothelium dependent relaxation: role of tetrahydrobiopterin. Am J Physiol Heart Circ Physiol 2004; 287: H2448-53.
-
(2004)
Am J Physiol Heart Circ Physiol
, vol.287
-
-
Blackwell, K.A.1
Sorenson, J.P.2
Richardson, D.M.3
Smith, L.A.4
Suda, O.5
Nath, K.6
Katusic, Z.S.7
-
72
-
-
55449136486
-
Inflammation and endothelial dysfunction during aging: Role of NF-Kb
-
Csiszar A, Wang M, Lakatta EG, Ungvari Z. Inflammation and endothelial dysfunction during aging: role of NF-Kb. J Appl Physiol 2008; 105: 1333-41.
-
(2008)
J Appl Physiol
, vol.105
, pp. 1333-1341
-
-
Csiszar, A.1
Wang, M.2
Lakatta, E.G.3
Ungvari, Z.4
-
73
-
-
0034634281
-
Harrison Endothelial dysfunction in cardiovascular diseases: The role of oxidant stress
-
Hua Cai and David G. Harrison Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress. Circ Res 2000; 87(10): 840-4.
-
(2000)
Circ Res
, vol.87
, Issue.10
, pp. 840-844
-
-
Cai, H.1
David, G.2
-
74
-
-
0036238915
-
The role of apoptosis in the normal aging brain, skeletal muscle, and heart
-
Pollack M, Phaneuf S, Dirks A, Leeuwenburgh C. The role of apoptosis in the normal aging brain, skeletal muscle, and heart. Ann NY Acad Sci 2002; 959: 93-107.
-
(2002)
Ann NY Acad Sci
, vol.959
, pp. 93-107
-
-
Pollack, M.1
Phaneuf, S.2
Dirks, A.3
Leeuwenburgh, C.4
-
76
-
-
0344392953
-
Apoptosis and oxidants in the heart
-
Kumar D, Jugdutt BI. Apoptosis and oxidants in the heart. J Lab Clin Med 2003; 142: 288-97.
-
(2003)
J Lab Clin Med
, vol.142
, pp. 288-297
-
-
Kumar, D.1
Jugdutt, B.I.2
-
77
-
-
27744433573
-
Effects of ovariectomy and growth hormone administration on body composition and vascular function and structure and in old female rats
-
Castillo C, Ariznavarreta MC, Lahera V, Cachofeiro V, Gil-Loyzaga P, Tresguerres JA. Effects of ovariectomy and growth hormone administration on body composition and vascular function and structure and in old female rats. Biogerontology 2005; 6: 49-60.
-
(2005)
Biogerontology
, vol.6
, pp. 49-60
-
-
Castillo, C.1
Ariznavarreta, M.C.2
Lahera, V.3
Cachofeiro, V.4
Gil-Loyzaga, P.5
Tresguerres, J.A.6
-
78
-
-
60349124651
-
Endothelial ageing: Molecular mechanisms and functional significance
-
Brown MD. Endothelial ageing: molecular mechanisms and functional significance. Exp Physiol 2009; 94: 297-8.
-
(2009)
Exp Physiol
, vol.94
, pp. 297-298
-
-
Brown, M.D.1
-
79
-
-
0024475227
-
NF-kappa B: A pleiotropic mediator of inducible and tissue-specific gene control
-
Lenardo MJ, Baltimore D. NF-kappa B: a pleiotropic mediator of inducible and tissue-specific gene control. Cell 1989; 58: 227-9.
-
(1989)
Cell
, vol.58
, pp. 227-229
-
-
Lenardo, M.J.1
Baltimore, D.2
-
80
-
-
0035082777
-
Characterization of aging-associated up-regulation of constitutive nuclear factor-kappa B binding activity
-
Helenius M, Kyrylenko S, Vehviläinen P, Salminen A. Characterization of aging-associated up-regulation of constitutive nuclear factor-kappa B binding activity. Antioxidants & Redox Signaling 2001; 3: 147-56.
-
(2001)
Antioxidants & Redox Signaling
, vol.3
, pp. 147-156
-
-
Helenius, M.1
Kyrylenko, S.2
Vehviläinen, P.3
Salminen, A.4
-
82
-
-
0037112204
-
Molecular inflammation hypothesis of aging based on the anti-aging mechanism of calorie restriction
-
Chung HY, Kim HJ, Kim KW, Choi JS, Yu BP. Molecular inflammation hypothesis of aging based on the anti-aging mechanism of calorie restriction. Microsc Res Tech 2002; 59: 264-72.
-
(2002)
Microsc Res Tech
, vol.59
, pp. 264-272
-
-
Chung, H.Y.1
Kim, H.J.2
Kim, K.W.3
Choi, J.S.4
Yu, B.P.5
-
84
-
-
33847607366
-
Chronic melatonin treatment reduces the age-dependent inflammatory process in senescence-accelerated mice
-
Rodríguez MI, Escames G, López LC, López A, García JA, Ortiz F, Acuña-Castroviejo D. Chronic melatonin treatment reduces the age-dependent inflammatory process in senescence-accelerated mice. J Pineal Res 2007; 42:272-9.
-
(2007)
J Pineal Res
, vol.42
, pp. 272-279
-
-
Rodríguez, M.I.1
Escames, G.2
López, L.C.3
López, A.4
García, J.A.5
Ortiz, F.6
Acuña-Castroviejo, D.7
-
85
-
-
36849008650
-
Cardiovascular diseases: Protective effects of melatonin
-
Tengattini S, Reiter RJ, Tan DX, Terron MP, Rodella LF, Rezzani R. Cardiovascular diseases: protective effects of melatonin. J Pineal Res 2008; 44:16-25.
-
(2008)
J Pineal Res
, vol.44
, pp. 16-25
-
-
Tengattini, S.1
Reiter, R.J.2
Tan, D.X.3
Terron, M.P.4
Rodella, L.F.5
Rezzani, R.6
-
86
-
-
0034740584
-
Expression of the MT1 melatonin receptor subtype in human coronary arteries
-
Ekmekcioglu C, Haslmayer P, Philipp C, et al. Expression of the MT1 melatonin receptor subtype in human coronary arteries. J Recept Signal Transduct Res 2001; 21:85-91.
-
(2001)
J Recept Signal Transduct Res
, vol.21
, pp. 85-91
-
-
Ekmekcioglu, C.1
Haslmayer, P.2
Philipp, C.3
-
87
-
-
10744232166
-
The melatonin receptor subtype MT2 is present in the human cardiovascular system
-
Ekmekcioglu C, Thalhammer T, Humpeler S, et al. The melatonin receptor subtype MT2 is present in the human cardiovascular system. J Pineal Res 2003; 35:40-4.
-
(2003)
J Pineal Res
, vol.35
, pp. 40-44
-
-
Ekmekcioglu, C.1
Thalhammer, T.2
Humpeler, S.3
-
88
-
-
0036721503
-
MT(2) melatonin receptors are present and functional in rat caudal artery
-
Masana MI, Doolen S, Ersahin C, et al. MT(2) melatonin receptors are present and functional in rat caudal artery. J Pharmacol Exp Ther 2002; 302: 1295-302.
-
(2002)
J Pharmacol Exp Ther
, vol.302
, pp. 1295-1302
-
-
Masana, M.I.1
Doolen, S.2
Ersahin, C.3
-
89
-
-
0037192558
-
Constitutively active melatonin MT1 receptors in male rat caudal arteries
-
Erşahin C, Masana MI, Dubocovich ML. Constitutively active melatonin MT1 receptors in male rat caudal arteries. Eur J Pharmacol 2002; 439:171-2.
-
(2002)
Eur J Pharmacol
, vol.439
, pp. 171-172
-
-
Erşahin, C.1
Masana, M.I.2
Dubocovich, M.L.3
-
90
-
-
0029762091
-
Suppression of UV-induced erythema by topical treatment with melatonin (N-acetyl-5-methoxytryptamine). A dose response study
-
Bangha E, Elsner P, Kistler GS. Suppression of UV-induced erythema by topical treatment with melatonin (N-acetyl-5-methoxytryptamine). A dose response study. Arch Dermatol Res 1996; 288: 522-6.
-
(1996)
Arch Dermatol Res
, vol.288
, pp. 522-526
-
-
Bangha, E.1
Elsner, P.2
Kistler, G.S.3
-
91
-
-
0030840267
-
Suppression of UV-induced erythema by topical treatment with melatonin (N-acetyl-5-methoxytryptamine). Influence of the application time point
-
Bangha E, Elsner P, Kistler GS. Suppression of UV-induced erythema by topical treatment with melatonin (N-acetyl-5-methoxytryptamine). Influence of the application time point. Dermatology 1997; 195: 248-52.
-
(1997)
Dermatology
, vol.195
, pp. 248-252
-
-
Bangha, E.1
Elsner, P.2
Kistler, G.S.3
-
92
-
-
0028056803
-
Ultraviolet light-induced free radical formation in skin: An electron paramagnetic resonance study
-
Jurkiewicz BA, Buettner GR. Ultraviolet light-induced free radical formation in skin: an electron paramagnetic resonance study. Photochem Photobiol 1994; 59: 1-4.
-
(1994)
Photochem Photobiol
, vol.59
, pp. 1-4
-
-
Jurkiewicz, B.A.1
Buettner, G.R.2
-
93
-
-
84885861231
-
Melatonin Serum Concentration in Psoriasis, Klinefelters-Syndrome and Spina-Bifida
-
Birau N and Schloot W. Melatonin Serum Concentration in Psoriasis, Klinefelters-Syndrome and Spina-Bifida. Acta Endocrinologica 1979; 91: 240.
-
(1979)
Acta Endocrinologica
, vol.91
, pp. 240
-
-
Birau, N.1
Schloot, W.2
-
95
-
-
0141702110
-
Neuroprotective role of melatonin in oxidative stress vulnerable brain
-
Gupta YK, Gupta M and Kohli K. Neuroprotective role of melatonin in oxidative stress vulnerable brain. Indian J.Physiol Pharmacol 2003; 47: 373-86.
-
(2003)
Indian J.Physiol Pharmacol
, vol.47
, pp. 373-386
-
-
Gupta, Y.K.1
Gupta, M.2
Kohli, K.3
-
96
-
-
0031733003
-
Melatonin counteracts ischemia-induced apoptosis in human retinal pigment epithelial cells
-
Osborne NN, Nash MS, and Wood JP. Melatonin counteracts ischemia-induced apoptosis in human retinal pigment epithelial cells. Invest Ophthalmol Vis Sci 1998; 39: 2374-83.
-
(1998)
Invest Ophthalmol Vis Sci
, vol.39
, pp. 2374-2383
-
-
Osborne, N.N.1
Nash, M.S.2
Wood, J.P.3
-
97
-
-
0042869981
-
Melatonin and cell death: Differential actions on apoptosis in normal and cancer cells
-
Sainz RM, Mayo JC, Rodriguez C, Tan DX, Lopez-Burillo S, Reiter RJ. Melatonin and cell death: differential actions on apoptosis in normal and cancer cells. Cell Mol Life Sci 2003; 60: 1407-26.
-
(2003)
Cell Mol Life Sci
, vol.60
, pp. 1407-1426
-
-
Sainz, R.M.1
Mayo, J.C.2
Rodriguez, C.3
Tan, D.X.4
Lopez-Burillo, S.5
Reiter, R.J.6
|