Modulation of heme oxygenase in tissue injury and its implication in protection against gastrointestinal diseases

Life Sciences

Volumn 69, Issue 25-26, 2001, Pages 3113-3119

  Guo, Xin ^a   Shin, Vivian Yvonne ^a   Cho, Chi Hin ^a,b  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b 1/F Li Shu Fan Building ^*  (Hong Kong)

Author keywords

Gastrointestinal diseases; Heme oxygenase; Inflammation; Tissue injury

Indexed keywords

BILIRUBIN; BILIVERDIN; CARBON MONOXIDE; CYTOKINE; ENDOTOXIN; ENZYME; HEAVY METAL; HEME; HEME OXYGENASE; IRON; TRINITROBENZENESULFONIC ACID;

BRAIN INJURY; CATABOLISM; COLON INJURY; CONFERENCE PAPER; DISEASE ASSOCIATION; ENZYME INDUCTION; GASTROINTESTINAL DISEASE; GASTROINTESTINAL TRACT; HUMAN; INFLAMMATION; INTESTINE INJURY; KIDNEY; KIDNEY INJURY; LIVER INJURY; LIVER PROTECTION; LUNG; NEUROPROTECTION; NONHUMAN; PROTECTION; PROTEIN EXPRESSION; TISSUE INJURY;

ANIMALS; BRAIN INJURIES; COLON; CYTOPROTECTION; DISEASE MODELS, ANIMAL; ENZYME INDUCTION; GASTROINTESTINAL DISEASES; HEME OXYGENASE (DECYCLIZING); HEME OXYGENASE-1; HUMANS; INFLAMMATION; KIDNEY; LIVER; MALE; MEMBRANE PROTEINS; RATS; REPERFUSION INJURY; TRINITROBENZENESULFONIC ACID; WOUNDS AND INJURIES;

EID: 0035834304     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(01)01417-5     Document Type: Conference Paper

References (30)

1. The enzymatic conversion of heme fo bilirubin by microsomal heme oxygenase
2. Overview of HO-1 in inflammatory pathologies
3. The indispensability of heme oxygenase-1 in protecting against acute heme protein-induced toxicity in vivo
4. Heme oxygenase: Who needs it?
5. Heme oxygenase: Recent advances in understanding its regulation and role
6. Heme oxygenase inhibits nitric oxide synthase by degrading heme: A negative feedback regulation mechanism for nitric oxide production
7. The heme oxygenase pathway and its interaction with nitric oxide in the control of cellular homeostasis
8. New physiological importance of two classic residual products: Carbon monoxide and bilirubin
9. Effect of tumor necrosis factor-α and interleukin-1α on heme oxygenase-1 expression in human endothelial cells
10. Expression of the antioxidant stress protein heme oxygenase-1 (HO-1) in human leukocytes
11. Heme oxygenase: A novel target for the modulation of the inflammatory response
12. Heme oxygenase isoform expression in cellular and antibody-mediated models of acute inflammation in the rat
13. Heme oxygenase induction with attenuation of experimentally induced corneal inflammation
14. Heme oxygenase is induced in nephrotoxic nephritis and hemin, a stimulator of heme oxygenase synthesis, ameliorates disease
15. Reversal of HO-1 related cytoprotection with increased expression is due to reactive iron
16. Focal hyperexpression of hemeoxygenase-1 protein and messenger RNA in rat brain caused by cellular stress following subarachnoid injections of lysed blood
17. Overexpression of heme oxygenase-1 is neuroprotective in a model of permanent middle cerebral artery occlusion in transgenic mice
18. Upregulation of heme oxygenase-1 protects genetically fat Zucker rat livers from ischemia/reperfusion injury
19. Doxorubicin preconditioning: A protection against rat hepatic ischemia-reperfusion injury
20. Glomerular inflammation induces resistance to tubular injury in the rat. A novel form of acquired, heme oxygenase-dependent resistance to renal injury
21. Spin trap (N-t-butyl-alpha-phenylnitrone)-mediated suprainduction of heme oxygenase-1 in kidney ischemia/reperfusion model: Role of the oxygenase in protection against oxidative injury
22. Exogenous administration of heme oxygenase-1 by gene transfer provides protection against hyperoxia-induced lung injury
23. Balloon injury does not induce heme oxygenase-1 expression, but administration of hemin inhibits neointimal formation in balloon-injured rat carotid artery
24. Cytoprotective role of antioxidant stress protein induced by adenosine A1 receptor antagonist in rat heart ischemic injury
25. Characterization of heme oxygenase in the small intestinal epithelium
26. Induction of heme oxygenase in intestinal epithelial cells: Studies in Caco-2 cell cultures
27. Distribution of heme oxygenase and effects of exogenous carbon monoxide in canine jejunum
28. Induction of heme oxygenase-1 as a response in sensing the signals evoked by distinct nitric oxide donors
29. Glutamine-induced heme oxygenase-1 protects intestines and hearts from warm ischemic injury
30. The protective effect of heme oxygenase-1 induction on the experimental colitis induced by trinitrobenzene sulfonic acid in rats