Surface-modified HK:siRNA nanoplexes with enhanced pharmacokinetics and tumor growth inhibition

Biomacromolecules

Volumn 14, Issue 3, 2013, Pages 752-760

  Chou, Szu Ting ^a,b   Leng, Qixin ^a   Scaria, Puthupparampil ^c   Kahn, Jason D ^d   Tricoli, Lucas J ^d   Woodle, Martin ^c   Mixson, A James ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MARYLAND   (United States)

^c Aparna Biosciences Corporation   (United States)

^d University of Maryland   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI-TUMOR EFFICACY; INHIBITION OF TUMOR GROWTH; LUCIFERASE ACTIVITIES; NON-INVASIVE IMAGING; SURFACE-MODIFIED; SYSTEMIC ADMINISTRATION; TARGETING LIGANDS; TUMOR LOCALIZATION;

AMINO ACIDS; BLOOD; DISEASE CONTROL; LIGANDS; PHARMACOKINETICS;

TUMORS;

ALPHAVBETA5 INTEGRIN; ANTINEOPLASTIC AGENT; ARGINYLGLYCYLASPARTIC ACID; HISTIDINE; LUCIFERASE; LYSINE; RAF PROTEIN; SMALL INTERFERING RNA; VITRONECTIN RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CONTROLLED STUDY; DRUG BLOOD LEVEL; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN TARGETING;

ANIMALS; CELL LINE, TUMOR; FEMALE; GENE EXPRESSION; GENE SILENCING; HISTIDINE; HUMANS; LYSINE; MICE; NANOSTRUCTURES; NEOPLASMS; PROTO-ONCOGENE PROTEINS C-RAF; RNA, SMALL INTERFERING; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84874894682     PISSN: 15257797     EISSN: 15264602     Source Type: Journal    
DOI: 10.1021/bm3018356     Document Type: Article

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