메뉴 건너뛰기




Volumn 107, Issue 47, 2010, Pages 20370-20375

Human tumor virus utilizes exosomes for intercellular communication

Author keywords

Herpesvirus; Oncogene

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; LATENT MEMBRANE PROTEIN 1; MICRORNA; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B;

EID: 78650553841     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1014194107     Document Type: Article
Times cited : (443)

References (38)
  • 1
    • 0036435166 scopus 로고    scopus 로고
    • Epstein-Barr virus in the pathogenesis of NPC
    • Raab-Traub N (2002) Epstein-Barr virus in the pathogenesis of NPC. Semin Cancer Biol 12:431-441.
    • (2002) Semin Cancer Biol , vol.12 , pp. 431-441
    • Raab-Traub, N.1
  • 3
    • 0022309824 scopus 로고
    • An EBV membrane protein expressed in immortalized lymphocytes transforms established rodent cells
    • Wang D, Liebowitz D, Kieff E (1985) An EBV membrane protein expressed in immortalized lymphocytes transforms established rodent cells. Cell 43:831-840.
    • (1985) Cell , vol.43 , pp. 831-840
    • Wang, D.1    Liebowitz, D.2    Kieff, E.3
  • 4
    • 70349210826 scopus 로고    scopus 로고
    • Role of the Epstein-Barr virus-encoded latent membrane protein-1, LMP1, in the pathogenesis of nasopharyngeal carcinoma
    • Morris MA, Dawson CW, Young LS (2009) Role of the Epstein-Barr virus-encoded latent membrane protein-1, LMP1, in the pathogenesis of nasopharyngeal carcinoma. Future Oncol 5:811-825.
    • (2009) Future Oncol , vol.5 , pp. 811-825
    • Morris, M.A.1    Dawson, C.W.2    Young, L.S.3
  • 5
    • 0029063936 scopus 로고
    • The Epstein-Barr virus latent membrane protein 1 induces expression of the epidermal growth factor receptor
    • Miller WE, Earp HS, Raab-Traub N (1995) The Epstein-Barr virus latent membrane protein 1 induces expression of the epidermal growth factor receptor. J Virol 69:4390-4398.
    • (1995) J Virol , vol.69 , pp. 4390-4398
    • Miller, W.E.1    Earp, H.S.2    Raab-Traub, N.3
  • 6
    • 0033230736 scopus 로고    scopus 로고
    • The EGFR as a target for viral oncoproteins
    • Miller WE, Raab-Traub N (1999) The EGFR as a target for viral oncoproteins. Trends Microbiol 7:453-458.
    • (1999) Trends Microbiol , vol.7 , pp. 453-458
    • Miller, W.E.1    Raab-Traub, N.2
  • 7
    • 62649095692 scopus 로고    scopus 로고
    • Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR
    • Al-Nedawi K, Meehan B, Kerbel RS, Allison AC, Rak J (2009) Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR. Proc Natl Acad Sci USA 106:3794-3799.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 3794-3799
    • Al-Nedawi, K.1    Meehan, B.2    Kerbel, R.S.3    Allison, A.C.4    Rak, J.5
  • 8
    • 57049103401 scopus 로고    scopus 로고
    • Glioblastomamicrovesicles transportRNAandproteins thatpromote tumour growth and provide diagnostic biomarkers
    • SkogJ, et al. (2008) Glioblastomamicrovesicles transportRNAandproteins thatpromote tumour growth and provide diagnostic biomarkers. Nat Cell Biol 10:1470-1476.
    • (2008) Nat Cell Biol , vol.10 , pp. 1470-1476
    • Skog, J.1
  • 9
    • 43149120419 scopus 로고    scopus 로고
    • Exosome function: From tumor immunology to pathogen biology
    • Schorey JS, Bhatnagar S (2008) Exosome function: From tumor immunology to pathogen biology. Traffic 9:871-881.
    • (2008) Traffic , vol.9 , pp. 871-881
    • Schorey, J.S.1    Bhatnagar, S.2
  • 10
    • 67949097489 scopus 로고    scopus 로고
    • Exosomes-vesicular carriers for intercellular communication
    • Simons M, Raposo G (2009) Exosomes-vesicular carriers for intercellular communication. Curr Opin Cell Biol 21:575-581.
    • (2009) Curr Opin Cell Biol , vol.21 , pp. 575-581
    • Simons, M.1    Raposo, G.2
  • 11
    • 51849117744 scopus 로고    scopus 로고
    • Human herpesvirus-6 induces MVB formation, and virus egress occurs by an exosomal release pathway
    • Mori Y, et al. (2008) Human herpesvirus-6 induces MVB formation, and virus egress occurs by an exosomal release pathway. Traffic 9:1728-1742.
    • (2008) Traffic , vol.9 , pp. 1728-1742
    • Mori, Y.1
  • 12
    • 33846864645 scopus 로고    scopus 로고
    • Exosomes released by EBV-infected nasopharyngeal carcinoma cells convey the viral latent membrane protein 1 and the immunomodulatory protein galectin 9
    • Keryer-Bibens C, et al. (2006) Exosomes released by EBV-infected nasopharyngeal carcinoma cells convey the viral latent membrane protein 1 and the immunomodulatory protein galectin 9. BMC Cancer 6:283.
    • (2006) BMC Cancer , vol.6 , pp. 283
    • Keryer-Bibens, C.1
  • 13
    • 61849139471 scopus 로고    scopus 로고
    • Blood diffusion and Th1-suppressive effects of galectin-9- containing exosomes released by Epstein-Barr virus-infected nasopharyngeal carcinoma cells
    • Klibi J, et al. (2009) Blood diffusion and Th1-suppressive effects of galectin-9- containing exosomes released by Epstein-Barr virus-infected nasopharyngeal carcinoma cells. Blood 113:1957-1966.
    • (2009) Blood , vol.113 , pp. 1957-1966
    • Klibi, J.1
  • 14
    • 0034661694 scopus 로고    scopus 로고
    • Direct immunosuppressive effects of EBV-encoded latent membrane protein 1
    • Dukers DF, et al. (2000) Direct immunosuppressive effects of EBV-encoded latent membrane protein 1. J Immunol 165:663-670.
    • (2000) J Immunol , vol.165 , pp. 663-670
    • Dukers, D.F.1
  • 15
    • 34548212356 scopus 로고    scopus 로고
    • Epstein-Barr virus latent membrane protein 1 promotes concentration in multivesicular bodies of fibroblast growth factor 2 and its release through exosomes
    • Ceccarelli S, et al. (2007) Epstein-Barr virus latent membrane protein 1 promotes concentration in multivesicular bodies of fibroblast growth factor 2 and its release through exosomes. Int J Cancer 121:1494-1506.
    • (2007) Int J Cancer , vol.121 , pp. 1494-1506
    • Ceccarelli, S.1
  • 16
    • 34548814463 scopus 로고    scopus 로고
    • A new diagnostic marker for secreted Epstein Barr virus encoded LMP1 and BARF1 oncoproteins in the serum and saliva of patients with nasopharyngeal carcinoma
    • Houali K, et al. (2007) A new diagnostic marker for secreted Epstein Barr virus encoded LMP1 and BARF1 oncoproteins in the serum and saliva of patients with nasopharyngeal carcinoma. Clin Cancer Res 13:4993-5000.
    • (2007) Clin Cancer Res , vol.13 , pp. 4993-5000
    • Houali, K.1
  • 17
    • 0032822527 scopus 로고    scopus 로고
    • Nasopharyngeal carcinoma cell line (C666-1) consistently harbouring Epstein-Barr virus
    • Cheung ST, et al. (1999) Nasopharyngeal carcinoma cell line (C666-1) consistently harbouring Epstein-Barr virus. Int J Cancer 83:121-126.
    • (1999) Int J Cancer , vol.83 , pp. 121-126
    • Cheung, S.T.1
  • 18
    • 63649092087 scopus 로고    scopus 로고
    • Systemic presence and tumor-growth promoting effect of ovarian carcinoma released exosomes
    • Keller S, et al. (2009) Systemic presence and tumor-growth promoting effect of ovarian carcinoma released exosomes. Cancer Lett 278:73-81.
    • (2009) Cancer Lett , vol.278 , pp. 73-81
    • Keller, S.1
  • 19
    • 55749112807 scopus 로고    scopus 로고
    • Proteomic profiling of exosomes: Current perspectives
    • Simpson RJ, Jensen SS, Lim JW (2008) Proteomic profiling of exosomes: Current perspectives. Proteomics 8:4083-4099.
    • (2008) Proteomics , vol.8 , pp. 4083-4099
    • Simpson, R.J.1    Jensen, S.S.2    Lim, J.W.3
  • 20
    • 35348850792 scopus 로고    scopus 로고
    • Unique signaling properties of CTAR1 in LMP1-mediated transformation
    • Mainou BA, Everly DN, Jr., Raab-Traub N (2007) Unique signaling properties of CTAR1 in LMP1-mediated transformation. J Virol 81:9680-9692.
    • (2007) J Virol , vol.81 , pp. 9680-9692
    • Mainou, B.A.1    Everly Jr., D.N.2    Raab-Traub, N.3
  • 21
    • 34249302620 scopus 로고    scopus 로고
    • Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells
    • Valadi H, et al. (2007) Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat Cell Biol 9:654-659.
    • (2007) Nat Cell Biol , vol.9 , pp. 654-659
    • Valadi, H.1
  • 22
    • 77950889558 scopus 로고    scopus 로고
    • Functional delivery of viral miRNAs via exosomes
    • Pegtel DM, et al. (2010) Functional delivery of viral miRNAs via exosomes. Proc Natl Acad Sci USA 107:6328-6333.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 6328-6333
    • Pegtel, D.M.1
  • 23
    • 33645758064 scopus 로고    scopus 로고
    • Epstein-Barr virus microRNAs are evolutionarily conserved and differentially expressed
    • Cai X, et al. (2006) Epstein-Barr virus microRNAs are evolutionarily conserved and differentially expressed. PLoS Pathog 2:e23.
    • (2006) PLoS Pathog , vol.2
    • Cai, X.1
  • 24
    • 0025169060 scopus 로고
    • Novel transcription from the Epstein-Barr virus terminal EcoRI fragment, DIJhet, in a nasopharyngeal carcinoma
    • Gilligan K, et al. (1990) Novel transcription from the Epstein-Barr virus terminal EcoRI fragment, DIJhet, in a nasopharyngeal carcinoma. J Virol 64:4948-4956.
    • (1990) J Virol , vol.64 , pp. 4948-4956
    • Gilligan, K.1
  • 25
    • 77951783385 scopus 로고    scopus 로고
    • The immunological synapse: A focal point for endocytosis and exocytosis
    • Griffiths GM, Tsun A, Stinchcombe JC (2010) The immunological synapse: A focal point for endocytosis and exocytosis. J Cell Biol 189:399-406.
    • (2010) J Cell Biol , vol.189 , pp. 399-406
    • Griffiths, G.M.1    Tsun, A.2    Stinchcombe, J.C.3
  • 26
    • 39149132089 scopus 로고    scopus 로고
    • ESCRT complexes and the biogenesis of multivesicular bodies
    • Hurley JH (2008) ESCRT complexes and the biogenesis of multivesicular bodies. Curr Opin Cell Biol 20:4-11.
    • (2008) Curr Opin Cell Biol , vol.20 , pp. 4-11
    • Hurley, J.H.1
  • 28
    • 0041335560 scopus 로고    scopus 로고
    • Ubiquitination of the Epstein-Barr virus-encoded latent membrane protein 1 depends on the integrity of the TRAF binding site
    • Rothenberger S, Burns K, Rousseaux M, Tschopp J, Bron C (2003) Ubiquitination of the Epstein-Barr virus-encoded latent membrane protein 1 depends on the integrity of the TRAF binding site. Oncogene 22:5614-5618.
    • (2003) Oncogene , vol.22 , pp. 5614-5618
    • Rothenberger, S.1    Burns, K.2    Rousseaux, M.3    Tschopp, J.4    Bron, C.5
  • 29
    • 0013495952 scopus 로고    scopus 로고
    • Proteomic and biochemical analyses of human B cell-derived exosomes. Potential implications for their function and multivesicular body formation
    • Wubbolts R, et al. (2003) Proteomic and biochemical analyses of human B cell-derived exosomes. Potential implications for their function and multivesicular body formation. J Biol Chem 278:10963-10972.
    • (2003) J Biol Chem , vol.278 , pp. 10963-10972
    • Wubbolts, R.1
  • 30
    • 10344245532 scopus 로고    scopus 로고
    • TRAF interactions with raft-like buoyant complexes, better than TRAF rates of degradation, differentiate signaling by CD40 and EBV latent membrane protein 1
    • Ardila-Osorio H, et al. (2005) TRAF interactions with raft-like buoyant complexes, better than TRAF rates of degradation, differentiate signaling by CD40 and EBV latent membrane protein 1. Int J Cancer 113:267-275.
    • (2005) Int J Cancer , vol.113 , pp. 267-275
    • Ardila-Osorio, H.1
  • 31
    • 0347088997 scopus 로고    scopus 로고
    • Latent infection membrane protein transmembrane FWLY is critical for intermolecular interaction, raft localization, and signaling
    • Yasui T, Luftig M, Soni V, Kieff E (2004) Latent infection membrane protein transmembrane FWLY is critical for intermolecular interaction, raft localization, and signaling. Proc Natl Acad Sci USA 101:278-283.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 278-283
    • Yasui, T.1    Luftig, M.2    Soni, V.3    Kieff, E.4
  • 32
    • 32944473016 scopus 로고    scopus 로고
    • Virus entry: Open sesame
    • Marsh M, Helenius A (2006) Virus entry: Open sesame. Cell 124:729-740.
    • (2006) Cell , vol.124 , pp. 729-740
    • Marsh, M.1    Helenius, A.2
  • 33
    • 69949117622 scopus 로고    scopus 로고
    • Multivesicular bodies associate with components of miRNA effector complexes and modulate miRNA activity
    • Gibbings DJ, Ciaudo C, Erhardt M, Voinnet O (2009) Multivesicular bodies associate with components of miRNA effector complexes and modulate miRNA activity. Nat Cell Biol 11:1143-1149.
    • (2009) Nat Cell Biol , vol.11 , pp. 1143-1149
    • Gibbings, D.J.1    Ciaudo, C.2    Erhardt, M.3    Voinnet, O.4
  • 34
    • 43949130116 scopus 로고    scopus 로고
    • Epstein-Barr virus latent membrane protein 1 induces expression of the epidermal growth factor receptor through effects on Bcl-3 and STAT3
    • Kung CP, Raab-Traub N (2008) Epstein-Barr virus latent membrane protein 1 induces expression of the epidermal growth factor receptor through effects on Bcl-3 and STAT3. J Virol 82:5486-5493.
    • (2008) J Virol , vol.82 , pp. 5486-5493
    • Kung, C.P.1    Raab-Traub, N.2
  • 35
    • 52049090124 scopus 로고    scopus 로고
    • EBV latent membrane protein 1 effects on plakoglobin, cell growth, and migration
    • Shair KH, Schnegg CI, Raab-Traub N (2008) EBV latent membrane protein 1 effects on plakoglobin, cell growth, and migration. Cancer Res 68:6997-7005.
    • (2008) Cancer Res , vol.68 , pp. 6997-7005
    • Shair, K.H.1    Schnegg, C.I.2    Raab-Traub, N.3
  • 36
    • 66449086207 scopus 로고    scopus 로고
    • Proteomics of MUC1-containing lipid rafts from plasma membranes and exosomes of human breast carcinoma cells MCF-7
    • Staubach S, Razawi H, Hanisch FG (2009) Proteomics of MUC1-containing lipid rafts from plasma membranes and exosomes of human breast carcinoma cells MCF-7. Proteomics 9:2820-2835.
    • (2009) Proteomics , vol.9 , pp. 2820-2835
    • Staubach, S.1    Razawi, H.2    Hanisch, F.G.3
  • 37
    • 70350681050 scopus 로고    scopus 로고
    • Paracrine induction of endothelium by tumor exosomes
    • Consortium for Translational Research in Advanced Imaging and Nanomedicine (C-TRAIN)
    • Hood JL, Pan H, Lanza GM, Wickline SA; Consortium for Translational Research in Advanced Imaging and Nanomedicine (C-TRAIN) (2009) Paracrine induction of endothelium by tumor exosomes. Lab Invest 89:1317-1328.
    • (2009) Lab Invest , vol.89 , pp. 1317-1328
    • Hood, J.L.1    Pan, H.2    Lanza, G.M.3    Wickline, S.A.4
  • 38
    • 50949104366 scopus 로고    scopus 로고
    • Epstein-Barr virus BART microRNAs are produced from a large intron prior to splicing
    • Edwards RH, Marquitz AR, Raab-Traub N (2008) Epstein-Barr virus BART microRNAs are produced from a large intron prior to splicing. J Virol 82:9094-9106.
    • (2008) J Virol , vol.82 , pp. 9094-9106
    • Edwards, R.H.1    Marquitz, A.R.2    Raab-Traub, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.