Systemic delivery of siRNA with cationic lipid assisted PEG-PLA nanoparticles for cancer therapy

Journal of Controlled Release

Volumn 156, Issue 2, 2011, Pages 203-211

  Yang, Xian Zhu ^a   Dou, Shuang ^b   Sun, Tian Meng ^a   Mao, Cheng Qiong ^b   Wang, Hong Xia ^b   Wang, Jun ^b  

^a UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

^b UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

Author keywords

Cancer therapy; Nanoparticle; Polo like kinase 1; RNA interference; siRNA delivery

Indexed keywords

CANCER CELLS; CANCER THERAPY; CATIONIC LIPIDS; D , L-LACTIDE; DISEASE TREATMENT; DOUBLE EMULSION-SOLVENT EVAPORATION; DOWN-REGULATION; ENCAPSULATION EFFICIENCY; ENDOSOMES; GENE KNOCK DOWN; HEPG2 CELLS; LIVER CANCERS; LOADING WEIGHT; LUCIFERASE EXPRESSION; MURINE XENOGRAFT MODEL; ORTHOTOPIC; POLO-LIKE KINASE; POLO-LIKE KINASE 1; POLYMERIC NANOPARTICLES; RNA INTERFERENCE; SIRNA DELIVERY; SMALL INTERFERING RNA (SIRNA); TUMOR GROWTH;

CELL DEATH; DISEASES; EMULSIFICATION; ENCAPSULATION; ENZYMES; ETHYLENE; GLYCOLS; NANOPARTICLES; ONCOLOGY; ORGANIC SOLVENTS; POLYETHYLENE GLYCOLS; RNA;

GENE THERAPY;

LIPID; LUCIFERASE; MACROGOL; NANOPARTICLE; POLO LIKE KINASE 1; POLYLACTIDE; SMALL INTERFERING RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER CELL; CANCER THERAPY; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; EMULSION; ENCAPSULATION; ENDOSOME; GENE EXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR GROWTH; TUMOR XENOGRAFT;

ANIMALS; CELL CYCLE PROTEINS; CELL LINE, TUMOR; GENE THERAPY; HUMANS; MICE; MICE, INBRED BALB C; MICE, NUDE; NANOPARTICLES; NEOPLASMS; POLYETHYLENE GLYCOLS; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 81255157791     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2011.07.035     Document Type: Article

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