메뉴 건너뛰기




Volumn 15, Issue 8, 2008, Pages 485-495

Systemic delivery of HK Raf-1 siRNA polyplexes inhibits MDA-MB-435 xenografts

Author keywords

Histidine; Lysine; Peptides; Raf 1; Tumor xenograft

Indexed keywords

HISTIDINE; LYSINE; MESSENGER RNA; POLYMER; RAF PROTEIN; SMALL INTERFERING RNA;

EID: 48349135578     PISSN: 09291903     EISSN: 14765500     Source Type: Journal    
DOI: 10.1038/cgt.2008.29     Document Type: Article
Times cited : (47)

References (28)
  • 1
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE, Mello CC. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 1998; 391: 806-811.
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3    Kostas, S.A.4    Driver, S.E.5    Mello, C.C.6
  • 2
    • 4444220551 scopus 로고    scopus 로고
    • Steroid and lipid conjugates of siRNAs to enhance cellular uptake and gene silencing in liver cells
    • Lorenz C, Hadwiger P, John M, Vornlocher HP, Unverzagt C. Steroid and lipid conjugates of siRNAs to enhance cellular uptake and gene silencing in liver cells. Bioorg Med Chem Lett 2004; 14: 4975-4977.
    • (2004) Bioorg Med Chem Lett , vol.14 , pp. 4975-4977
    • Lorenz, C.1    Hadwiger, P.2    John, M.3    Vornlocher, H.P.4    Unverzagt, C.5
  • 3
    • 2442668068 scopus 로고    scopus 로고
    • A small interfering RNA targeting vascular endothelial growth factor as cancer therapeutics
    • Takei Y, Kadomatsu K, Yuzawa Y, Matsuo S, Muramatsu T. A small interfering RNA targeting vascular endothelial growth factor as cancer therapeutics. Cancer Res 2004; 64: 3365-3370.
    • (2004) Cancer Res , vol.64 , pp. 3365-3370
    • Takei, Y.1    Kadomatsu, K.2    Yuzawa, Y.3    Matsuo, S.4    Muramatsu, T.5
  • 4
    • 25444482607 scopus 로고    scopus 로고
    • Sequence-specific knockdown of EWS-FLI1 by targeted, nonviral delivery of small interfering RNA inhibits tumor growth in a murine model of metastatic Ewing's sarcoma
    • Hu-Lieskovan S, Heidel JD, Bartlett DW, Davis ME, Triche TJ. Sequence-specific knockdown of EWS-FLI1 by targeted, nonviral delivery of small interfering RNA inhibits tumor growth in a murine model of metastatic Ewing's sarcoma. Cancer Res 2005; 65: 8984-8992.
    • (2005) Cancer Res , vol.65 , pp. 8984-8992
    • Hu-Lieskovan, S.1    Heidel, J.D.2    Bartlett, D.W.3    Davis, M.E.4    Triche, T.J.5
  • 5
    • 34347272315 scopus 로고    scopus 로고
    • Administration in non-human primates of escalating intravenous doses of targeted nanoparticles containing ribonucleotide reductase subunit M2 siRNA
    • Heidel JD, Yu Z, Liu JY, Rele SM, Liang Y, Zeidan RK et al. Administration in non-human primates of escalating intravenous doses of targeted nanoparticles containing ribonucleotide reductase subunit M2 siRNA. Proc Natl Acad Sci USA 2007; 104: 5715-5721.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 5715-5721
    • Heidel, J.D.1    Yu, Z.2    Liu, J.Y.3    Rele, S.M.4    Liang, Y.5    Zeidan, R.K.6
  • 6
    • 33947696667 scopus 로고    scopus 로고
    • Physicochemical and biological characterization of targeted, nucleic acid-containing nanoparticles
    • Bartlett DW, Davis ME. Physicochemical and biological characterization of targeted, nucleic acid-containing nanoparticles. Bioconjug Chem 2007; 18: 456-468.
    • (2007) Bioconjug Chem , vol.18 , pp. 456-468
    • Bartlett, D.W.1    Davis, M.E.2
  • 7
    • 14544298301 scopus 로고    scopus 로고
    • Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle
    • Schiffelers RM, Ansari A, Xu J, Zhou Q, Tang Q, Storm G et al. Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle. Nucleic Acids Res 2004; 32: e149.
    • (2004) Nucleic Acids Res , vol.32
    • Schiffelers, R.M.1    Ansari, A.2    Xu, J.3    Zhou, Q.4    Tang, Q.5    Storm, G.6
  • 8
    • 24744466699 scopus 로고    scopus 로고
    • Using siRNA in prophylactic and therapeutic regimens against SARS coronavirus in Rhesus macaque
    • Li BJ, Tang Q, Cheng D, Qin C, Xie FY, Wei Q et al. Using siRNA in prophylactic and therapeutic regimens against SARS coronavirus in Rhesus macaque. Nat Med 2005; 11: 944-951.
    • (2005) Nat Med , vol.11 , pp. 944-951
    • Li, B.J.1    Tang, Q.2    Cheng, D.3    Qin, C.4    Xie, F.Y.5    Wei, Q.6
  • 9
    • 23844474160 scopus 로고    scopus 로고
    • Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors
    • Song E, Zhu P, Lee SK, Chowdhury D, Kussman S, Dykxhoorn DM et al. Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors. Nat Biotechnol 2005; 23: 709-717.
    • (2005) Nat Biotechnol , vol.23 , pp. 709-717
    • Song, E.1    Zhu, P.2    Lee, S.K.3    Chowdhury, D.4    Kussman, S.5    Dykxhoorn, D.M.6
  • 11
    • 33846014254 scopus 로고    scopus 로고
    • A branched histidine/lysine peptide, H2K4b, in complex with plasmids encoding antitumor proteins inhibits tumor xenografts
    • Leng Q, Scaria P, Ioffe OB, Woodle M, Mixson AJ. A branched histidine/lysine peptide, H2K4b, in complex with plasmids encoding antitumor proteins inhibits tumor xenografts. J Gene Med 2006; 8: 1407-1415.
    • (2006) J Gene Med , vol.8 , pp. 1407-1415
    • Leng, Q.1    Scaria, P.2    Ioffe, O.B.3    Woodle, M.4    Mixson, A.J.5
  • 13
    • 22944469778 scopus 로고    scopus 로고
    • Small interfering RNA targeting Raf-1 inhibits tumor growth in vitro and in vivo
    • Leng Q, Mixson AJ. Small interfering RNA targeting Raf-1 inhibits tumor growth in vitro and in vivo. Cancer Gene Ther 2005; 12: 682-690.
    • (2005) Cancer Gene Ther , vol.12 , pp. 682-690
    • Leng, Q.1    Mixson, A.J.2
  • 14
    • 0037085731 scopus 로고    scopus 로고
    • Optimal transfection with the HK polymer depends on its degree of branching and the pH of endocytic vesicles
    • Chen QR, Zhang L, Luther PW, Mixson AJ. Optimal transfection with the HK polymer depends on its degree of branching and the pH of endocytic vesicles. Nucleic Acids Res 2002; 30: 1338-1345.
    • (2002) Nucleic Acids Res , vol.30 , pp. 1338-1345
    • Chen, Q.R.1    Zhang, L.2    Luther, P.W.3    Mixson, A.J.4
  • 15
    • 0033759241 scopus 로고    scopus 로고
    • Co-polymer of histidine and lysine markedly enhances transfection of liposomes
    • Chen QR, Zhang L, Stass SA, Mixson AJ. Co-polymer of histidine and lysine markedly enhances transfection of liposomes. Gene Therapy 2000; 7: 698-704.
    • (2000) Gene Therapy , vol.7 , pp. 698-704
    • Chen, Q.R.1    Zhang, L.2    Stass, S.A.3    Mixson, A.J.4
  • 16
    • 17144433510 scopus 로고    scopus 로고
    • Enhanced transfection efficiency of a systemically delivered tumor-targeting immunolipoplex by inclusion of a pH-sensitive histidylated oligolysine peptide
    • Yu W, Pirollo KF, Yu B, Rait A, Xiang L, Huang W et al. Enhanced transfection efficiency of a systemically delivered tumor-targeting immunolipoplex by inclusion of a pH-sensitive histidylated oligolysine peptide. Nucleic Acids Res 2004; 32: e48.
    • (2004) Nucleic Acids Res , vol.32
    • Yu, W.1    Pirollo, K.F.2    Yu, B.3    Rait, A.4    Xiang, L.5    Huang, W.6
  • 17
    • 0037329372 scopus 로고    scopus 로고
    • RNA interference is a functional pathway with therapeutic potential in human myeloid leukemia cell lines
    • Cioca DP, Aoki Y, Kiyosawa K. RNA interference is a functional pathway with therapeutic potential in human myeloid leukemia cell lines. Cancer Gene Ther 2003; 10: 125-133.
    • (2003) Cancer Gene Ther , vol.10 , pp. 125-133
    • Cioca, D.P.1    Aoki, Y.2    Kiyosawa, K.3
  • 18
    • 0032483514 scopus 로고    scopus 로고
    • Protein kinase G mediates vascular endothelial growth factor-induced Raf-1 activation and proliferation in human endothelial cells
    • Hood J, Granger HJ. Protein kinase G mediates vascular endothelial growth factor-induced Raf-1 activation and proliferation in human endothelial cells. J Biol Chem 1998; 273: 23504-23508.
    • (1998) J Biol Chem , vol.273 , pp. 23504-23508
    • Hood, J.1    Granger, H.J.2
  • 19
    • 8444253256 scopus 로고    scopus 로고
    • Delivery of a liposomal c-raf-1 antisense oligonucleotide by weekly bolus dosing in patients with advanced solid tumors: A phase I study
    • Rudin CM, Marshall JL, Huang CH, Kindler HL, Zhang C, Kumar D et al. Delivery of a liposomal c-raf-1 antisense oligonucleotide by weekly bolus dosing in patients with advanced solid tumors: a phase I study. Clin Cancer Res 2004; 10: 7244-7251.
    • (2004) Clin Cancer Res , vol.10 , pp. 7244-7251
    • Rudin, C.M.1    Marshall, J.L.2    Huang, C.H.3    Kindler, H.L.4    Zhang, C.5    Kumar, D.6
  • 20
    • 1842479976 scopus 로고    scopus 로고
    • Combination with liposome-entrapped, ends-modified raf antisense oligonucleotide (LErafAON) improves the anti-tumor efficacies of cisplatin, epirubicin, mitoxantrone, docetaxel and gemcitabine
    • Pei J, Zhang C, Gokhale PC, Rahman A, Dritschilo A, Ahmad I et al. Combination with liposome-entrapped, ends-modified raf antisense oligonucleotide (LErafAON) improves the anti-tumor efficacies of cisplatin, epirubicin, mitoxantrone, docetaxel and gemcitabine. Anticancer Drugs 2004; 15: 243-253.
    • (2004) Anticancer Drugs , vol.15 , pp. 243-253
    • Pei, J.1    Zhang, C.2    Gokhale, P.C.3    Rahman, A.4    Dritschilo, A.5    Ahmad, I.6
  • 21
    • 0028834638 scopus 로고
    • Both v-Ha-Ras and v-Raf stimulate expression of the vascular endothelial growth factor in NIH 3T3 cells
    • Grugel S, Finkenzeller G, Weindel K, Barleon B, Marme D. Both v-Ha-Ras and v-Raf stimulate expression of the vascular endothelial growth factor in NIH 3T3 cells. J Biol Chem 1995; 270: 25915-25919.
    • (1995) J Biol Chem , vol.270 , pp. 25915-25919
    • Grugel, S.1    Finkenzeller, G.2    Weindel, K.3    Barleon, B.4    Marme, D.5
  • 22
    • 0042386426 scopus 로고    scopus 로고
    • Differential alphav integrin-mediated Ras-ERK signaling during two pathways of angiogenesis
    • Hood JD, Frausto R, Kiosses WB, Schwartz MA, Cheresh DA. Differential alphav integrin-mediated Ras-ERK signaling during two pathways of angiogenesis. J Cell Biol 2003; 162: 933-943.
    • (2003) J Cell Biol , vol.162 , pp. 933-943
    • Hood, J.D.1    Frausto, R.2    Kiosses, W.B.3    Schwartz, M.A.4    Cheresh, D.A.5
  • 23
    • 0036791127 scopus 로고    scopus 로고
    • Inhibition of hepatic endothelial E-selectin expression by C-raf antisense oligonucleotides blocks colorectal carcinoma liver metastasis
    • Khatib AM, Fallavollita L, Wancewicz EV, Monia BP, Brodt P. Inhibition of hepatic endothelial E-selectin expression by C-raf antisense oligonucleotides blocks colorectal carcinoma liver metastasis. Cancer Res 2002; 62: 5393-5398.
    • (2002) Cancer Res , vol.62 , pp. 5393-5398
    • Khatib, A.M.1    Fallavollita, L.2    Wancewicz, E.V.3    Monia, B.P.4    Brodt, P.5
  • 24
    • 46549085186 scopus 로고    scopus 로고
    • Needle-like morphology of H2K4b polyplexes associated with increases in transfection in vitro
    • Leng Q, Kahn J, Zhu J, Scaria P, Mixson J. Needle-like morphology of H2K4b polyplexes associated with increases in transfection in vitro. Cancer Ther 2007; 5B: 193-202.
    • (2007) Cancer Ther , vol.5 B , pp. 193-202
    • Leng, Q.1    Kahn, J.2    Zhu, J.3    Scaria, P.4    Mixson, J.5
  • 25
    • 0035869214 scopus 로고    scopus 로고
    • Branched co-polymers of histidine and lysine are efficient carriers of plasmids
    • Chen QR, Zhang L, Stass SA, Mixson AJ. Branched co-polymers of histidine and lysine are efficient carriers of plasmids. Nucleic Acids Res 2001; 29: 1334-1340.
    • (2001) Nucleic Acids Res , vol.29 , pp. 1334-1340
    • Chen, Q.R.1    Zhang, L.2    Stass, S.A.3    Mixson, A.J.4
  • 27
    • 0345357073 scopus 로고    scopus 로고
    • Transferrin-containing, cyclodextrin polymer-based particles for tumor-targeted gene delivery
    • Bellocq NC, Pun SH, Jensen GS, Davis ME. Transferrin-containing, cyclodextrin polymer-based particles for tumor-targeted gene delivery. Bioconjug Chem 2003; 14: 1122-1132.
    • (2003) Bioconjug Chem , vol.14 , pp. 1122-1132
    • Bellocq, N.C.1    Pun, S.H.2    Jensen, G.S.3    Davis, M.E.4
  • 28
    • 0141715047 scopus 로고    scopus 로고
    • Integrin targeting using RGD-PEI conjugates for in vitro gene transfer
    • Kunath K, Merdan T, Hegener O, Haberlein H, Kissel T. Integrin targeting using RGD-PEI conjugates for in vitro gene transfer. J Gene Med 2003; 5: 588-599.
    • (2003) J Gene Med , vol.5 , pp. 588-599
    • Kunath, K.1    Merdan, T.2    Hegener, O.3    Haberlein, H.4    Kissel, T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.