α(v) Integrins mediate adhesion and migration of breast carcinoma cell lines

Clinical and Experimental Metastasis

Volumn 16, Issue 1, 1998, Pages 50-61

  Wong, Nanette C ^a   Mueller, Barbara M ^b   Barbas, Carlos F ^b   Ruminski, Pete ^c   Quaranta, Vito ^b   Lin, Emme C K ^a   Smith, Jeffrey W ^a  

^a BURNHAM INSTITUTE   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c PFIZER INC   (United States)

Author keywords

Adhesion; Integrin; Invasion; Metastasis; Migration

Indexed keywords

INTEGRIN; CD51 ANTIGEN; LEUKOCYTE ANTIGEN; TUMOR PROTEIN; VITRONECTIN;

ARTICLE; BREAST CARCINOGENESIS; BREAST CARCINOMA; BREAST METASTASIS; CELL ADHESION; CELL MIGRATION; HUMAN; HUMAN CELL; MALIGNANT TRANSFORMATION; PROTEIN EXPRESSION; BREAST TUMOR; CARCINOMA; CELL CULTURE; CELL MOTION; ENZYMOLOGY; FEMALE; FLOW CYTOMETRY; ISOLATION AND PURIFICATION; PATHOLOGY; PHYSIOLOGY; SERODIAGNOSIS;

ANTIGENS, CD; BREAST NEOPLASMS; CARCINOMA; CELL ADHESION; CELL MOVEMENT; FEMALE; FLOW CYTOMETRY; HUMANS; INTEGRIN ALPHAV; INTEGRINS; NEOPLASM PROTEINS; PRECIPITIN TESTS; TUMOR CELLS, CULTURED; VITRONECTIN;

EID: 0031594601     PISSN: 02620898     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1006512018609     Document Type: Article

References (60)

1. Miller AB and Bulbrook RD, 1986, UICC multi-disciplinary project on breast cancer: the epidemiology, aetiology and prevention of breast cancer. Int J Cancer, 37, 173-7.
2. Clarke R, Dickson RB and Brunner N, 1990, The process of malignant progression in human breast cancer. Ann Oncol, 1, 401-7.
3. van de Vijer MJ, 1993, Molecular genetic changes in human breast cancer. In: Vande Woude GF and Klein G, eds. Advances in Cancer Research. San Diego: Academic Press, pp. 25-56.
4. Hynes RO, 1987, Integrins: a family of cell surface receptors. Cell, 48, 549-50.
5. Albelda SM and Buck CA, 1990, Integrins and other cell adhesion molecules. FASEB J, 4, 2868-80.
6. Schwartz MA, 1993, Signaling by integrins: implications for tumorigenesis. Cancer Res, 53, 1503-6.
7. Schwartz MA, Brown EJ and Fazeli B, 1993, A 50-kDa integrin-associated protein is required for integrin-regulated calcium entry in endothelial cells. J Biol Chem, 268, 19931-4.
8. 3 rescues melanoma cells from apoptosis in three-dimensional dermal collagen. Proc Natl Acad Sci USA, 91, 8856-60.
9. 3 by osteopontin stimulates phosphatidylinositol 3-hydroxyl kinase activity. Endocrinology, 136, 2984-92.
10. 3. Cell, 85, 683-93.
11. Zutter MM, Krigman HR and Santoro SA, 1993, Altered integrin expression in adenocarcinoma of the breast. Am J Pathol, 142, 1439-48.
12. Jones JL, Critchley DR and Walker RA, 1992, Alteration of stromal protein and integrin expression in breast - A marker of premalignant change. J Pathol. 167, 399-406.
13. 4 integrin subunits coincides with loss of basement membrane components in oral squamous cell carcinomas. J Pathol, 171, 183-90.
14. Pignatelli M, Cardillo MR, Hanby A and Stamp GWH, 1992, Integrins and their accessory adhesion molecules in mammary carcinomas: Loss of polarization in poorly differentiated tumors. Hum Pathol, 23, 1159-66.
15. Staatz WD, Rajpara SM, Wayner EA, Carter WG and Santoro SA, 1989, The membrane glycoprotein Ia-IIa (VLA-2) complex mediates the Mg++-dependent adhesion of platelets to collagen. J Cell Biol, 108, 1917-24.
16. Elices MJ and Hemler ME, 1989, The human integrin VLA-2 is a collagen receptor on some cells and a collagen/laminin receptor on others. Proc Natl Acad Sci USA, 86, 9906-10.
17. 4 is a laminin receptor. J Cell Biol, 117, 671-8.
18. Clczardin P, Frappart L, Clerget M, Pechoux C and Delmas PD, 1993, Expression of thrombospondin (TSP1) and it receptors (CD36 and CD51) in normal, hyperplastic and neoplastic human breast. Cancer Res, 53, 1421-30.
19. 3 expression by bone-residing breast cancer metastases. Diag Mol Pathol, 5, 127-35.
20. Hynes RO, 1992, Integrins: versatility, modulation and signaling in cell adhesion. Cell, 69, 11-25.
21. 1). J Biol Chem, 265, 5934-7.
22. v subunit to form a novel vitronectin receptor in a human embryonic kidney cell line. J Biol Chem, 265, 5938-41.
23. 5. J Biol Chem, 265, 11008-13.
24. 6 as a fibronectin-binding protein. J Biol Chem, 267, 5790-6.
25. 5 integrin receptor regulates receptor-mediated endocytosis of vitronectin. J Biol Chem, 268, 11492-5.
26. 3-mediated endothelial cell migration is triggered through distinct signaling mechanisms. J Cell Biol, 121, 163-70.
27. 1 integrin functions as a fibronectin receptor but does not support fibronectin matrix assembly and cell migration on fibronectin. J Cell Biol, 122, 235-42.
28. 3 subunit with tumor progression. Cancer Res, 50, 6757-64.
29. Price JE, Polyzos A, Zhang RD and Daniels LM, 1990, Tumorigenicity and metastasis of human breast carcinoma cell lines in nude mice. Cancer Res, 50, 717-21.
30. Shafie SM and Liotta LA, 1980, Formation of metastasis by human breast carcinoma cells (MCF-7) in nude mice. Cancer Lett, 11, 81-7.
31. Kurebayashi J, Mcleskey S, Johnson MD, et al. 1993, Quantitative demonstration of spontaneous metastasis of MCF-7 human breast cancer cells co-transfected with fibroblast growth factor 4 and LacZ. Cancer Res, 53, 2178-87.
32. Yatohgo T, Izumi M, Kashiwagi H and Hayashi M, 1988, Novel purification of vitronectin from human plasma by heparin affinity chromatography. Cell Struct Funct, 13, 281-92.
33. Doolittle RF, Schubert D and Schwartz SA, 1967, Amino acid sequence studies of an artiodtactyl fibrinopeptide I. Dromedary camel, mule deer and cape buffalo. Arch Biochem Biophys, 118, 456-521.
34. 5. Hybridoma, 14, 545-550.
35. Cheresh DA and Spiro RC, 1987, Biosynthetic and functional properties of an Arg-Gly-Asp-directed receptor involved in human melanoma cell attachment to vitronectin, fibrinogen, and von Willebrand Factor. J Biol Chem, 262, 17703-11.
36. Newman PJ, Allen RW, Kahn RA and Kunicki TJ, 1985, Quantitation of membrane glycoprotein IIIa on intact human platelets using the monoclonal antibody, AP-3. Blood, 65, 227-32.
37. Patent Cooperation Treaty International Application. Title: Platelet Aggregation Inhibitors. PCT NO.WO 96/23771, 1996.
38. Barbas CF, Languino LR and Smith JW, 1993, High-affinity self-reactive human antibodies by design and selection: targeting the integrin ligand binding site. Proc Natl Acad Sci USA, 90, 10003-7.
39. Smith JW, Hu D, Satterthwait A, Pinz-Sweeney S and Barbas CF, 1994, Building synthetic antibodies as adhesive ligands for integrins. J Biol Chem, 269, 32788-95.
40. Pratner CA, Plotkin J, Jaye D and Frazier WA, 1991, The properdin-like type I repeats of human thrombospondin contain a cell attachment site. J Cell Biol, 112, 1031-40.
41. Bauer JS, Schreiner CL, Giancotti FG, Ruoslahti E and Juliano RL, 1992, Motility of fibronectin receptor-deficient cells on fibronectin and vitronectin: collaborative interactions among integrins. J Cell Biol, 116, 477-87.
42. Pytela R, Pierschbacher MD, Argraves S, Suziki S and Ruoslahti E, 1987, Arginine-glycine-aspartic acid adhesion receptors. Meth Enzymol, 144, 475-89.
43. 3 integrin. J Cell Biochem, 16F, 152.
44. Lawler J, Weinstein R and Hynes RO, 1988, Cell attachment to thrombospondin: the role of Arg-Gly-Asp, calcium and integrin receptors. J Cell Biol, 107, 2351-61.
45. Zablocki JA, Miyano M, Garland RB, et al. 1993, Potent in vitro and in vivo inhibitors of platelet aggregation based upon the Arg-Gly-Asp-Phe sequence of fibrinogen. A proposal on the nature of the binding interaction between the Arg-guanidine of RGDX mimetics and the platelet GP IIb-IIIa receptor. J Med Chem, 36, 1811-19.
46. Ruoslahti E and Giancotti FG, 1989, Integrins and tumor cell dissemination. Cancer Cells, 1, 119-26.
47. v gene expression in human melanoma tumorigenicity. J Clin Invest, 89, 2018-22.
48. Humphries MJ, Olden K and Yamada KM, 1986, A synthetic peptide from fibronectin inhibits experimental metastasis of murine melanoma cells. Science, 233, 467-9.
49. Soszka T, Knudsen KA, Beviglia L, Rossi C, Poggi A and Niewiarowski S, 1991, Inhibition of murine melanoma cell-matrix adhesion and experimental metastasis by albolabrin, an RGD-containing peptide isolated from the venom of Trimeresurus albolabris. Exp Cell Res, 196, 6-12.
50. Ugen KE, Mahalingam M, Klein PA and Kao KJ, 1988, Inhibition of tumor cell-induced platelet aggregation and experimental tumor metastasis by the synthetic Gly-Arg-Gly-Asp-Ser peptide. J Natl Cancer Inst, 80, 1461-6.
51. Isoai A, Ueno Y, Giga-Hama Y, Goto H and Kumagai H, 1992, A novel Arg-Gly-Asp containing peptide specific for platelet aggregation and its effect on tumor metastasis: a possible mechanism of RGD peptide-mediated inhibition of tumor metastasis. Cancer Lett, 65, 259-64.
52. Hayman EG, Pierschbacher MD, Ohgren Y and Ruoslahti E, 1983, Serum spreading factor (vitro-nectin) is present at the cell surface and in tissues. Proc Natl Acad Sci USA, 80, 4003-7.
53. Simpson APF and Horton MA, 1989, Expression of the vitronectin receptor during embryonic development: an immunohistological study of the ontogeny of the osteoclast in rabbit. Br J Exp Pathol, 70. 257-65.
54. 3 to adhere to lymph node vitronectin. J Clin Invest, 90, 1406-13.
55. 5 contribute to cell attachment to vitronectin but differentially distribute on the cell surface. J Cell Biol, 113, 919-29.
56. 3 subunit for carcinoma cell spreading or migration on vitronectin and fibrinogen. J Cell Biol, 117, 1101-7.
57. 3 integrin with a small peptide antagonist GpenGRGDSPCA. J Vasc Surg, 19, 125-34.
58. 1 subunit with a variant cytoplasmic domain. J Biol Chem, 267, 7116-20.
59. Wei Y, Lukashev M, Simon DI, et al. 1996, Regulation of integrin function by the urokinase receptor. Science, 273, 1551-5.
60. Topol EJ and Plow EF, 1993, Clinical trials of platelet receptor inhibitors. Thromb Haemost, 70, 94-8.