Modified branched peptides with a histidine-rich tail enhance in vitro gene transfection

Nucleic Acids Research

Volumn 33, Issue 4, 2005, Pages 1-9

  Leng, Qixin ^a   Mixson, A James ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; BUFFER; HISTIDINE; LIPOSOME; LYSINE; NUCLEIC ACID; PEPTIDE DERIVATIVE; PLASMID DNA; POLYMER; BIOPOLYMER; H2K4BT PROTEIN; PEPTIDE;

ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; CULTURE MEDIUM; FLOW CYTOMETRY; GENETIC TRANSFECTION; HETEROZYGOTE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; PARTICLE SIZE; PRIORITY JOURNAL; PROTEIN DNA INTERACTION; PROTEIN MODIFICATION; STAINING; AMINO ACID SEQUENCE; CELL SURVIVAL; CHEMISTRY; EVALUATION; GENETICS; METHODOLOGY; MOLECULAR GENETICS; PLASMID; TUMOR CELL LINE;

AMINO ACID SEQUENCE; BETA-GALACTOSIDASE; BIOPOLYMERS; CELL LINE, TUMOR; CELL SURVIVAL; HISTIDINE; HUMANS; LIPOSOMES; MOLECULAR SEQUENCE DATA; PEPTIDES; PLASMIDS; TRANSFECTION;

EID: 26644469058     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gni040     Document Type: Article

References (23)

1. Li,S. and Huang,L. (2000) Nonviral gene therapy: Promises and challenges. Gene Ther., 7, 31-34.
2. Subramanian,A., Ranganathan,P. and Diamond,S.L. (1999) Nuclear targeting peptide scaffolds for lipofection of nondividing mammalian cells. Nat. Biotechnol., 17, 873-877.
3. Uchida,E., Mizuguchi,H., Ishii-Watabe,A. and Hayakawa,T. (2002) Comparison of the efficiency and safety of non-viral vector-mediated gene transfer into a wide range of human cells. Biol. Pharm. Bull. 25, 891-897.
4. Chen,Q.R., Zhang,L., Stass,S.A. and Mixson,A.J. (2000) Co-polymer of histidine and lysine markedly enhances transfection of liposomes. Gene Ther., 7, 698-704.
5. Midoux,P. and Monsigny,M. (1999) Efficient gene transfer by histidylated polylysine/pDNA complexes. Bioconjug. Chem., 10, 406-411.
6. Pichon,C., Roufai,M.B., Monsigny,M. and Midoux,P. (2000) Histidylated oligolysines increase the transmembrane passage and the biological activity of antisense oligonucleotides. Nucleic Acids Res., 28 504-512.
7. Niidome,T., Ohmori,N., Ichinose,A., Wada,A., Mihara,H., Hirayama,T. and Aoyagi,H. (1997) Binding of cationic alpha-helical peptides to plasmid DNA and their gene transfer abilities into cells. J. Biol. Chem., 272, 15307-15312.
8. Morris,M.C., Chaloin,L., Mery,J., Heitz,F. and Divita,G. (1999) A novel potent strategy for gene delivery using a single peptide vector as a carrier. Nucleic Acids Res., 27, 3510-3517.
9. Wyman,T.B., Nicol,F., Zelphati,O., Scarla,P.V., Plank,C. and Szoka,F.C.,Jr (1997) Design, synthesis, and characterization of a cationic peptide that binds to nucleic acids and permeabilizes bilayers. Biochemistry, 36, 3008-3017.
10. Boussif,O., Lezouac'h,F., Zanta,M.A., Mergny,M.D., Scherman,D., Demeneix,B. and Behr,J.P. (1995) A versatile vector for gene and oligonucleotide transfer into cell in culture and in vivo: polyethylenimine. Proc. Natl Acad. Sci. USA, 92, 7297-7300.
11. Ferrari,S., Moro,E., Pettenazzo,A., Behr,J.P., Zacchello,F. and Scarpa,M. (1997) ExGen 500 is an efficient vector for gene delivery to lung epithelial cells in vitro and in vivo. Gene Ther., 4 1100-1106.
12. Haensler,J. and Szoka,F.C. (1993) Polyamidoamine cascade polymers mediate efficient transfection of cells in culture. Bioconjug. Chem. 4, 372-379.
13. Kukowska-Latallo,J.F., Bielinska,A.U., Johnson,J., Spindler,R., Tomalia,D.A. and Baker,J.R.,Jr (1996) Efficient transfer of genetic material into mammalian cells using Starburst polyamidoamine dendrimers. Proc. Natl Acad. Sci. USA, 93, 4897-4902.
14. Chen,Q.R., Zhang,L., Stass,S.A. and Mixson,A.J. (2001) Branched co-polymers of histidine and lysine are efficient carriers of plasmids. Nucleic Acids Res., 29, 1334-1340.
15. Chen,Q.R., Zhang,L., Luther,P.W. and Mixson,A.J. (2002) Optimal transfection with the HK polymer depends on its degree of branching and the pH of endocytic vesicles. Nucleic Acids Res., 30, 1338-1345.
16. Zhang,L., Ambulos,N. and Mixson,A.J. (2004) DNA delivery to cells in culture using peptides. Methods Mol. Biol., 245, 33-52.
17. Tseng,W.C., Tang,C.H. and Fang,T.Y. (2004) The role of dextran conjugation in transfection mediated by dextran-grafted polyethylenimine. J. Gene Med., 6, 895-905.
18. Xu,M., Kumar,D., Srinivas,S., Detolla,L.J., Yu,S.F., Stass,S.A. and Mixson,A.J. (1997) Parenteral gene therapy with p53 inhibits human breast tumors in vivo through a bystander mechanism without evidence of toxicity. Hum. Gene Ther., 8, 177-185.
19. Tang,M.X., Redemann,C.T. and Szoka,F.C.,Jr (1996) In vitro gene delivery by degraded polyamidoamine dendrimers. Bioconjug. Chem., 7, 703-714.
20. Makkerh,J.P., Dingwall,C. and Laskey,R.A. (1996) Comparative mutagenesis of nuclear localization signals reveals the importance of neutral and acidic amino acids. Curr. Biol., 6, 1025-1027.
21. Ciolina,C., Byk,G., Blanche,F., Thuillier,V., Scherman,D. and Wils,P. (1999) Coupling of nuclear localization signals to plasmid DNA and specific interaction of the conjugates with importin alpha. Bioconjug. Chem., 10, 49-55.
22. Harbottle,R.P., Cooper,R.G., Hart,S.L., Ladhoff A., McKay,T., Knight,A.M., Wagner,E., Miller,A.D. and Coutelle,C. (1998) An RGD-oligolysine peptide: A prototype construct for integrin-mediated gene delivery. Hum. Gene Ther., 9, 1037-1047.
23. 64Cu-labeled RGD peptide. Bioconjug. Chem., 15, 41-49.