Topoisomerase IIβ deficiency enhances camptothecin-induced apoptosis

Journal of Biological Chemistry

Volumn 288, Issue 10, 2013, Pages 7182-7192

  Lin, Ren Kuo ^a   Ho, Chia Wen ^a   Liu, Leroy F ^a   Lyu, Yi Lisa ^a  

^a RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAMPTOTHECIN (CPT); RNA POLYMERASE II; TOPOISOMERASE II;

RNA;

BODY FLUIDS;

CAMPTOTHECIN; DNA TOPOISOMERASE (ATP HYDROLYSING); PROTEIN P53; RAZOXANE; TOPOISOMERASE IIBETA; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DNA DAMAGE; DOWN REGULATION; EMBRYO; ENZYME ASSAY; ENZYME DEFICIENCY; ENZYME DEGRADATION; INHIBITION KINETICS; MOLECULAR MODEL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEPLETION; PROTEIN INDUCTION; SENSITIVITY ANALYSIS; TRANSCRIPTION INITIATION;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BLOTTING, WESTERN; CAMPTOTHECIN; CELL SURVIVAL; CELLS, CULTURED; DNA TOPOISOMERASES, TYPE II; DNA-BINDING PROTEINS; DNA-DIRECTED RNA POLYMERASES; DOSE-RESPONSE RELATIONSHIP, DRUG; EMBRYO, MAMMALIAN; FIBROBLASTS; MICE; MICE, KNOCKOUT; PROTEIN SUBUNITS; RAZOXANE; TOPOISOMERASE I INHIBITORS; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84874848115     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.415471     Document Type: Article

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