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Volumn 15, Issue 1, 2013, Pages 1-24

Deregulated chromatin remodeling in the pathobiology of brain tumors

Author keywords

Brain tumors; Chromatin remodeling; DNA methylation inhibitors; Gliomas; Histone deacetylation inhibitors; Histone modifications

Indexed keywords

4 PHENYLBUTYRIC ACID; 5 AZA 2' DEOXYCYTIDINE; BEVACIZUMAB; BORTEZOMIB; BUTYRIC ACID; CISPLATIN; DNA; DNA METHYLTRANSFERASE INHIBITOR; ENTINOSTAT; ERLOTINIB; ETOPOSIDE; FIRTECAN; GEFITINIB; HISTONE; HISTONE DEACETYLASE; HISTONE DEACETYLASE INHIBITOR; HISTONE METHYLTRANSFERASE; PACLITAXEL; PANOBINOSTAT; PIVALOYLOXYMETHYL BUTYRATE; RETINOIC ACID; ROMIDEPSIN; SALINOSPORAMIDE A; TEMOZOLOMIDE; TRICHOSTATIN A; UNINDEXED DRUG; VALPROIC ACID; VANDETANIB; VINCRISTINE; VORINOSTAT;

EID: 84874736040     PISSN: 15351084     EISSN: 15591174     Source Type: Journal    
DOI: 10.1007/s12017-012-8205-y     Document Type: Review
Times cited : (18)

References (173)
  • 1
    • 67349128584 scopus 로고    scopus 로고
    • Reactivation of death receptor 4 (DR4) expression sensitizes medulloblastoma cell lines to TRAIL
    • 19148581
    • Aguilera, D. G.; Das, C. M.; Sinnappah-Kang, N. D.; Joyce, C.; Taylor, P. H.; Wen, S.; et al. (2009). Reactivation of death receptor 4 (DR4) expression sensitizes medulloblastoma cell lines to TRAIL. Journal of Neuro-oncology, 93, 303-318.
    • (2009) Journal of Neuro-oncology , vol.93 , pp. 303-318
    • Aguilera, D.G.1    Das, C.M.2    Sinnappah-Kang, N.D.3    Joyce, C.4    Taylor, P.H.5    Wen, S.6
  • 2
    • 20144387913 scopus 로고    scopus 로고
    • EMP3, a myelin-related gene located in the critical 19q13.3 region, is epigenetically silenced and exhibits features of a candidate tumor suppressor in glioma and neuroblastoma
    • DOI 10.1158/0008-5472.CAN-04-4283
    • Alaminos, M.; Davalos, V.; Ropero, S.; Setien, F.; Paz, M. F.; Herranz, M.; et al. (2005). EMP3, a myelin-related gene located in the critical 19q13.3 region, is epigenetically silenced and exhibits features of a candidate tumor suppressor in glioma and neuroblastoma. Cancer Research, 65, 2565-2571. (Pubitemid 40490052)
    • (2005) Cancer Research , vol.65 , Issue.7 , pp. 2565-2571
    • Alaminos, M.1    Davalos, V.2    Ropero, S.3    Setien, F.4    Paz, M.F.5    Herranz, M.6    Fraga, M.F.7    Mora, J.8    Cheung, N.-K.V.9    Gerald, W.L.10    Esteller, M.11
  • 5
    • 80055106066 scopus 로고    scopus 로고
    • Genetic and epigenetic modifications of Sox2 contribute to the invasive phenotype of malignant gliomas
    • 22069467
    • Alonso, M. M.; Diez-Valle, R.; Manterola, L.; Rubio, A.; Liu, D.; Cortes-Santiago, N.; et al. (2011). Genetic and epigenetic modifications of Sox2 contribute to the invasive phenotype of malignant gliomas. PLoS ONE, 6, e26740.
    • (2011) PLoS ONE , vol.6 , pp. 26740
    • Alonso, M.M.1    Diez-Valle, R.2    Manterola, L.3    Rubio, A.4    Liu, D.5    Cortes-Santiago, N.6
  • 6
    • 77951931604 scopus 로고    scopus 로고
    • Suberoylanilide hydroxamic acid limits migration and invasion of glioma cells in two and three dimensional culture
    • 20060208
    • An, Z.; Gluck, C. B.; Choy, M. L.; & Kaufman, L. J. (2010). Suberoylanilide hydroxamic acid limits migration and invasion of glioma cells in two and three dimensional culture. Cancer Letters, 292, 215-227.
    • (2010) Cancer Letters , vol.292 , pp. 215-227
    • An, Z.1    Gluck, C.B.2    Choy, M.L.3    Kaufman, L.J.4
  • 7
    • 57149120670 scopus 로고    scopus 로고
    • Global analysis of the medulloblastoma epigenome identifies disease-subgroup-specific inactivation of COL1A2
    • 18664619
    • Anderton, J. A.; Lindsey, J. C.; Lusher, M. E.; Gilbertson, R. J.; Bailey, S.; Ellison, D. W.; et al. (2008). Global analysis of the medulloblastoma epigenome identifies disease-subgroup-specific inactivation of COL1A2. Neuro-oncology, 10, 981-994.
    • (2008) Neuro-oncology , vol.10 , pp. 981-994
    • Anderton, J.A.1    Lindsey, J.C.2    Lusher, M.E.3    Gilbertson, R.J.4    Bailey, S.5    Ellison, D.W.6
  • 9
    • 79958254773 scopus 로고    scopus 로고
    • Chemosensitization of glioblastoma cells by the histone deacetylase inhibitor MS275
    • 21566522
    • Bangert, A.; Hacker, S.; Cristofanon, S.; Debatin, K. M.; & Fulda, S. (2011). Chemosensitization of glioblastoma cells by the histone deacetylase inhibitor MS275. Anti-Cancer Drugs, 22, 494-499.
    • (2011) Anti-Cancer Drugs , vol.22 , pp. 494-499
    • Bangert, A.1    Hacker, S.2    Cristofanon, S.3    Debatin, K.M.4    Fulda, S.5
  • 10
    • 34247465955 scopus 로고    scopus 로고
    • SnapShot: Chromatin remodeling complexes
    • 17482554
    • Bao, Y.; & Shen, X. (2007). SnapShot: Chromatin remodeling complexes. Cell, 129, 632.
    • (2007) Cell , vol.129 , pp. 632
    • Bao, Y.1    Shen, X.2
  • 11
    • 0035997356 scopus 로고    scopus 로고
    • Atp-dependent nucleosome remodeling
    • DOI 10.1146/annurev.biochem.71.110601.135400
    • Becker, P. B.; & Horz, W. (2002). ATP-dependent nucleosome remodeling. Annual Review of Biochemistry, 71, 247-273. (Pubitemid 34800221)
    • (2002) Annual Review of Biochemistry , vol.71 , pp. 247-273
    • Becker, P.B.1    Horz, W.2
  • 13
    • 51249101290 scopus 로고    scopus 로고
    • Selective repression of YKL-40 by NF-kappaB in glioma cell lines involves recruitment of histone deacetylase-1 and -2
    • 18708058
    • Bhat, K. P.; Pelloski, C. E.; Zhang, Y.; Kim, S. H.; deLaCruz, C.; Rehli, M.; et al. (2008). Selective repression of YKL-40 by NF-kappaB in glioma cell lines involves recruitment of histone deacetylase-1 and -2. FEBS Letters, 582, 3193-3200.
    • (2008) FEBS Letters , vol.582 , pp. 3193-3200
    • Bhat, K.P.1    Pelloski, C.E.2    Zhang, Y.3    Kim, S.H.4    Delacruz, C.5    Rehli, M.6
  • 14
    • 0032940605 scopus 로고    scopus 로고
    • Germ-line and acquired mutations of INI1 in atypical teratoid and rhabdoid tumors
    • Biegel, J. A.; Zhou, J. Y.; Rorke, L. B.; Stenstrom, C.; Wainwright, L. M.; & Fogelgren, B. (1999). Germ-line and acquired mutations of INI1 in atypical teratoid and rhabdoid tumors. Cancer Research, 59, 74-79. (Pubitemid 29062960)
    • (1999) Cancer Research , vol.59 , Issue.1 , pp. 74-79
    • Biegel, J.A.1    Zhou, J.-Y.2    Rorke, L.B.3    Stenstrom, C.4    Wainwright, L.M.5    Fogelgren, B.6
  • 15
    • 0036849922 scopus 로고    scopus 로고
    • Alterations of the hSNF5/INI1 gene in central nervous system atypical teratoid/rhabdoid tumors and renal and extrarenal rhabdoid tumors
    • Biegel, J. A.; Tan, L.; Zhang, F.; Wainwright, L.; Russo, P.; & Rorke, L. B. (2002). Alterations of the hSNF5/INI1 gene in central nervous system atypical teratoid/rhabdoid tumors and renal and extrarenal rhabdoid tumors. Clinical Cancer Research, 8, 3461-3467. (Pubitemid 35340722)
    • (2002) Clinical Cancer Research , vol.8 , Issue.11 , pp. 3461-3467
    • Biegel, J.A.1    Tan, L.2    Zhang, F.3    Wainwright, L.4    Russo, P.5    Rorke, L.B.6
  • 16
    • 39649117157 scopus 로고    scopus 로고
    • Chromatin proteomics and epigenetic regulatory circuits
    • DOI 10.1586/14789450.5.1.105
    • Bonisch, C.; Nieratschker, S. M.; Orfanos, N. K.; & Hake, S. B. (2008). Chromatin proteomics and epigenetic regulatory circuits. Expert Review of Proteomics, 5, 105-119. (Pubitemid 351287745)
    • (2008) Expert Review of Proteomics , vol.5 , Issue.1 , pp. 105-119
    • Bonisch, C.1    Nieratschker, S.M.2    Orfanos, N.K.3    Hake, S.B.4
  • 18
    • 0017698493 scopus 로고
    • Chromosomal aberrations in human neuroblastomas
    • Brodeur, G. M.; Sekhon, G.; & Goldstein, M. N. (1977). Chromosomal aberrations in human neuroblastomas. Cancer, 40, 2256-2263. (Pubitemid 8239715)
    • (1977) Cancer , vol.40 , Issue.5 , pp. 2256-2263
    • Brodeur, G.M.1    Sekhon, G.S.2    Goldstein, M.N.3
  • 19
    • 0033582914 scopus 로고    scopus 로고
    • Slit proteins bind robo receptors and have an evolutionarily conserved role in repulsive axon guidance
    • Brose, K.; Bland, K. S.; Wang, K. H.; Arnott, D.; Henzel, W.; Goodman, C. S.; et al. (1999). Slit proteins bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance. Cell, 96, 795-806. (Pubitemid 29165083)
    • (1999) Cell , vol.96 , Issue.6 , pp. 795-806
    • Brose, K.1    Bland, K.S.2    Kuan, H.W.3    Arnott, D.4    Henzel, W.5    Goodman, C.S.6    Tessier-Lavigne, M.7    Kidd, T.8
  • 20
    • 33846821916 scopus 로고    scopus 로고
    • High TGFβ-Smad Activity Confers Poor Prognosis in Glioma Patients and Promotes Cell Proliferation Depending on the Methylation of the PDGF-B Gene
    • DOI 10.1016/j.ccr.2006.11.023, PII S1535610806003813
    • Bruna, A.; Darken, R. S.; Rojo, F.; Ocana, A.; Penuelas, S.; Arias, A.; et al. (2007). High TGFbeta-Smad activity confers poor prognosis in glioma patients and promotes cell proliferation depending on the methylation of the PDGF-B gene. Cancer Cell, 11, 147-160. (Pubitemid 46209848)
    • (2007) Cancer Cell , vol.11 , Issue.2 , pp. 147-160
    • Bruna, A.1    Darken, R.S.2    Rojo, F.3    Ocana, A.4    Penuelas, S.5    Arias, A.6    Paris, R.7    Tortosa, A.8    Mora, J.9    Baselga, J.10    Seoane, J.11
  • 21
    • 33749039999 scopus 로고    scopus 로고
    • Genome-wide hypomethylation in human glioblastomas associated with specific copy number alteration, methylenetetrahydrofolate reductase allele status, and increased proliferation
    • DOI 10.1158/0008-5472.CAN-06-1547
    • Cadieux, B.; Ching, T. T.; VandenBerg, S. R.; & Costello, J. F. (2006). Genome-wide hypomethylation in human glioblastomas associated with specific copy number alteration, methylenetetrahydrofolate reductase allele status, and increased proliferation. Cancer Research, 66, 8469-8476. (Pubitemid 44449159)
    • (2006) Cancer Research , vol.66 , Issue.17 , pp. 8469-8476
    • Cadieux, B.1    Ching, T.-T.2    VandenBerg, S.R.3    Costello, J.F.4
  • 22
    • 79952085666 scopus 로고    scopus 로고
    • Expression of nuclear receptor corepressors and class i histone deacetylases in astrocytic gliomas
    • 21143702
    • Campos, B.; Bermejo, J. L.; Han, L.; Felsberg, J.; Ahmadi, R.; Grabe, N.; et al. (2011). Expression of nuclear receptor corepressors and class I histone deacetylases in astrocytic gliomas. Cancer Science, 102, 387-392.
    • (2011) Cancer Science , vol.102 , pp. 387-392
    • Campos, B.1    Bermejo, J.L.2    Han, L.3    Felsberg, J.4    Ahmadi, R.5    Grabe, N.6
  • 23
    • 75949106376 scopus 로고    scopus 로고
    • Histone deacetylase and Cullin3-REN(KCTD11) ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation
    • 20081843
    • Canettieri, G.; Di Marcotullio, L.; Greco, A.; Coni, S.; Antonucci, L.; Infante, P.; et al. (2010). Histone deacetylase and Cullin3-REN(KCTD11) ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation. Nature Cell Biology, 12, 132-142.
    • (2010) Nature Cell Biology , vol.12 , pp. 132-142
    • Canettieri, G.1    Di Marcotullio, L.2    Greco, A.3    Coni, S.4    Antonucci, L.5    Infante, P.6
  • 24
    • 79751526520 scopus 로고    scopus 로고
    • Identification of epigenetically regulated genes that predict patient outcome in neuroblastoma
    • 21314941
    • Caren, H.; Djos, A.; Nethander, M.; Sjoberg, R. M.; Kogner, P.; Enstrom, C.; et al. (2011). Identification of epigenetically regulated genes that predict patient outcome in neuroblastoma. BMC Cancer, 11, 66.
    • (2011) BMC Cancer , vol.11 , pp. 66
    • Caren, H.1    Djos, A.2    Nethander, M.3    Sjoberg, R.M.4    Kogner, P.5    Enstrom, C.6
  • 26
    • 67649770256 scopus 로고    scopus 로고
    • Epigenetic control of the invasion-promoting MT1-MMP/MMP-2/TIMP-2 axis in cancer cells
    • 19286653
    • Chernov, A. V.; Sounni, N. E.; Remacle, A. G.; & Strongin, A. Y. (2009). Epigenetic control of the invasion-promoting MT1-MMP/MMP-2/TIMP-2 axis in cancer cells. Journal of Biological Chemistry, 284, 12727-12734.
    • (2009) Journal of Biological Chemistry , vol.284 , pp. 12727-12734
    • Chernov, A.V.1    Sounni, N.E.2    Remacle, A.G.3    Strongin, A.Y.4
  • 27
    • 77953505957 scopus 로고    scopus 로고
    • Microarray-based transcriptional and epigenetic profiling of matrix metalloproteinases, collagens, and related genes in cancer
    • 20404328
    • Chernov, A. V.; Baranovskaya, S.; Golubkov, V. S.; Wakeman, D. R.; Snyder, E. Y.; Williams, R.; et al. (2010). Microarray-based transcriptional and epigenetic profiling of matrix metalloproteinases, collagens, and related genes in cancer. The Journal of Biological Chemistry, 285, 19647-19659.
    • (2010) The Journal of Biological Chemistry , vol.285 , pp. 19647-19659
    • Chernov, A.V.1    Baranovskaya, S.2    Golubkov, V.S.3    Wakeman, D.R.4    Snyder, E.Y.5    Williams, R.6
  • 28
    • 2542484533 scopus 로고    scopus 로고
    • Advances in chromatin remodeling and human disease
    • DOI 10.1016/j.gde.2004.04.015, PII S0959437X04000619
    • Cho, K. S.; Elizondo, L. I.; & Boerkoel, C. F. (2004). Advances in chromatin remodeling and human disease. Current Opinion in Genetics & Development, 14, 308-315. (Pubitemid 38686937)
    • (2004) Current Opinion in Genetics and Development , vol.14 , Issue.3 , pp. 308-315
    • Cho, K.S.1    Elizondo, L.I.2    Boerkoel, C.F.3
  • 29
    • 77954659099 scopus 로고    scopus 로고
    • Relationship between nucleosome positioning and DNA methylation
    • 20512117
    • Chodavarapu, R. K.; Feng, S.; Bernatavichute, Y. V.; Chen, P. Y.; Stroud, H.; Yu, Y.; et al. (2010). Relationship between nucleosome positioning and DNA methylation. Nature, 466, 388-392.
    • (2010) Nature , vol.466 , pp. 388-392
    • Chodavarapu, R.K.1    Feng, S.2    Bernatavichute, Y.V.3    Chen, P.Y.4    Stroud, H.5    Yu, Y.6
  • 30
    • 79954553605 scopus 로고    scopus 로고
    • Tumor-associated methylation of the putative tumor suppressor AJAP1 gene and association between decreased AJAP1 expression and shorter survival in patients with glioma
    • 21439246
    • Cogdell, D.; Chung, W.; Liu, Y.; McDonald, J. M.; Aldape, K.; Issa, J. P.; et al. (2011). Tumor-associated methylation of the putative tumor suppressor AJAP1 gene and association between decreased AJAP1 expression and shorter survival in patients with glioma. Chinese Journal of Cancer, 30, 247-253.
    • (2011) Chinese Journal of Cancer , vol.30 , pp. 247-253
    • Cogdell, D.1    Chung, W.2    Liu, Y.3    McDonald, J.M.4    Aldape, K.5    Issa, J.P.6
  • 31
    • 40649111338 scopus 로고    scopus 로고
    • Non-coding RNAs, epigenetics and complexity
    • 18226475
    • Costa, F. F. (2008). Non-coding RNAs, epigenetics and complexity. Gene, 410, 9-17.
    • (2008) Gene , vol.410 , pp. 9-17
    • Costa, F.F.1
  • 32
    • 76549121309 scopus 로고    scopus 로고
    • Reversing HOXA9 oncogene activation by PI3 K inhibition: Epigenetic mechanism and prognostic significance in human glioblastoma
    • 20068170
    • Costa, B. M.; Smith, J. S.; Chen, Y.; Chen, J.; Phillips, H. S.; Aldape, K. D.; et al. (2010). Reversing HOXA9 oncogene activation by PI3 K inhibition: epigenetic mechanism and prognostic significance in human glioblastoma. Cancer Research, 70, 453-462.
    • (2010) Cancer Research , vol.70 , pp. 453-462
    • Costa, B.M.1    Smith, J.S.2    Chen, Y.3    Chen, J.4    Phillips, H.S.5    Aldape, K.D.6
  • 33
    • 0043170818 scopus 로고    scopus 로고
    • Frequent epigenetic inactivation of the SLIT2 gene in gliomas
    • DOI 10.1038/sj.onc.1206687
    • Dallol, A.; Krex, D.; Hesson, L.; Eng, C.; Maher, E. R.; & Latif, F. (2003). Frequent epigenetic inactivation of the SLIT2 gene in gliomas. Oncogene, 22, 4611-4616. (Pubitemid 36920705)
    • (2003) Oncogene , vol.22 , Issue.29 , pp. 4611-4616
    • Dallol, A.1    Krex, D.2    Hesson, L.3    Eng, C.4    Maher, E.R.5    Latif, F.6
  • 34
    • 35448999681 scopus 로고    scopus 로고
    • Valproic acid induces p21 and topoisomerase-II (α/β) expression and synergistically enhances etoposide cytotoxicity in human glioblastoma cell lines
    • DOI 10.1007/s11060-007-9402-7
    • Das, C. M.; Aguilera, D.; Vasquez, H.; Prasad, P.; Zhang, M.; Wolff, J. E.; et al. (2007). Valproic acid induces p21 and topoisomerase-II (alpha/beta) expression and synergistically enhances etoposide cytotoxicity in human glioblastoma cell lines. Journal of Neuro-oncology, 85, 159-170. (Pubitemid 47629397)
    • (2007) Journal of Neuro-Oncology , vol.85 , Issue.2 , pp. 159-170
    • Das, C.M.1    Aguilera, D.2    Vasquez, H.3    Prasad, P.4    Zhang, M.5    Wolff, J.E.6    Gopalakrishnan, V.7
  • 35
    • 0032945178 scopus 로고    scopus 로고
    • The conditional probability of survival of patients with primary malignant brain tumors: Surveillance, epidemiology, and end results (SEER) data
    • DOI 10.1002/(SICI)1097-0142(19990115)85:2 <485::AID-CNCR29>3.0. CO;2-L
    • Davis, F. G.; McCarthy, B. J.; Freels, S.; Kupelian, V.; & Bondy, M. L. (1999). The conditional probability of survival of patients with primary malignant brain tumors: Surveillance, epidemiology, and end results (SEER) data. Cancer, 85, 485-491. (Pubitemid 29051306)
    • (1999) Cancer , vol.85 , Issue.2 , pp. 485-491
    • Davis, F.G.1    McCarthy, B.J.2    Freels, S.3    Kupelian, V.4    Bondy, M.L.5
  • 36
    • 58149183232 scopus 로고    scopus 로고
    • Phase i pharmacokinetic and pharmacodynamic study of LAQ824, a hydroxamate histone deacetylase inhibitor with a heat shock protein-90 inhibitory profile, in patients with advanced solid tumors
    • 18927309
    • de Bono, J. S.; Kristeleit, R.; Tolcher, A.; Fong, P.; Pacey, S.; Karavasilis, V.; et al. (2008). Phase I pharmacokinetic and pharmacodynamic study of LAQ824, a hydroxamate histone deacetylase inhibitor with a heat shock protein-90 inhibitory profile, in patients with advanced solid tumors. Clinical Cancer Research, 14, 6663-6673.
    • (2008) Clinical Cancer Research , vol.14 , pp. 6663-6673
    • De Bono, J.S.1    Kristeleit, R.2    Tolcher, A.3    Fong, P.4    Pacey, S.5    Karavasilis, V.6
  • 37
    • 0033539932 scopus 로고    scopus 로고
    • Alteration of hSNF5/INI1/BAF47 detected in rhabdoid cell lines and primary rhabdomyosarcomas but not Wilms' tumors
    • DeCristofaro, M. F.; Betz, B. L.; Wang, W.; & Weissman, B. E. (1999). Alteration of hSNF5/INI1/BAF47 detected in rhabdoid cell lines and primary rhabdomyosarcomas but not Wilms' tumors. Oncogene, 18, 7559-7565. (Pubitemid 30035057)
    • (1999) Oncogene , vol.18 , Issue.52 , pp. 7559-7565
    • DeCristofaro, M.F.1    Betz, B.L.2    Wang, W.3    Weissman, B.E.4
  • 39
    • 20444397430 scopus 로고    scopus 로고
    • Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF
    • DOI 10.1016/j.cell.2005.04.031, PII S0092867405004496
    • Dou, Y.; Milne, T. A.; Tackett, A. J.; Smith, E. R.; Fukuda, A.; Wysocka, J.; et al. (2005). Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF. Cell, 121, 873-885. (Pubitemid 40806419)
    • (2005) Cell , vol.121 , Issue.6 , pp. 873-885
    • Dou, Y.1    Milne, T.A.2    Tackett, A.J.3    Smith, E.R.4    Fukuda, A.5    Wysocka, J.6    Allis, C.D.7    Chait, B.T.8    Hess, J.L.9    Roeder, R.G.10
  • 40
    • 84861696508 scopus 로고    scopus 로고
    • Phase i study of panobinostat in combination with bevacizumab for recurrent high-grade glioma
    • 21984064
    • Drappatz, J.; Lee, E. Q.; Hammond, S.; Grimm, S. A.; Norden, A. D.; Beroukhim, R.; et al. (2012). Phase I study of panobinostat in combination with bevacizumab for recurrent high-grade glioma. Journal of Neuro-oncology, 107, 133-138.
    • (2012) Journal of Neuro-oncology , vol.107 , pp. 133-138
    • Drappatz, J.1    Lee, E.Q.2    Hammond, S.3    Grimm, S.A.4    Norden, A.D.5    Beroukhim, R.6
  • 41
    • 49649114803 scopus 로고    scopus 로고
    • Histone deacetylase inhibition and blockade of the glycolytic pathway synergistically induce glioblastoma cell death
    • 18483381
    • Egler, V.; Korur, S.; Failly, M.; Boulay, J. L.; Imber, R.; Lino, M. M.; et al. (2008). Histone deacetylase inhibition and blockade of the glycolytic pathway synergistically induce glioblastoma cell death. Clinical Cancer Research, 14, 3132-3140.
    • (2008) Clinical Cancer Research , vol.14 , pp. 3132-3140
    • Egler, V.1    Korur, S.2    Failly, M.3    Boulay, J.L.4    Imber, R.5    Lino, M.M.6
  • 42
    • 51649126841 scopus 로고    scopus 로고
    • Histone deacetylase inhibitor panobinostat induces clinical responses with associated alterations in gene expression profiles in cutaneous T-cell lymphoma
    • 18628465
    • Ellis, L.; Pan, Y.; Smyth, G. K.; George, D. J.; McCormack, C.; Williams-Truax, R.; et al. (2008). Histone deacetylase inhibitor panobinostat induces clinical responses with associated alterations in gene expression profiles in cutaneous T-cell lymphoma. Clinical Cancer Research, 14, 4500-4510.
    • (2008) Clinical Cancer Research , vol.14 , pp. 4500-4510
    • Ellis, L.1    Pan, Y.2    Smyth, G.K.3    George, D.J.4    McCormack, C.5    Williams-Truax, R.6
  • 43
    • 65949086183 scopus 로고    scopus 로고
    • Global histone modifications in breast cancer correlate with tumor phenotypes, prognostic factors, and patient outcome
    • 19366799
    • Elsheikh, S. E.; Green, A. R.; Rakha, E. A.; Powe, D. G.; Ahmed, R. A.; Collins, H. M.; et al. (2009). Global histone modifications in breast cancer correlate with tumor phenotypes, prognostic factors, and patient outcome. Cancer Research, 69, 3802-3809.
    • (2009) Cancer Research , vol.69 , pp. 3802-3809
    • Elsheikh, S.E.1    Green, A.R.2    Rakha, E.A.3    Powe, D.G.4    Ahmed, R.A.5    Collins, H.M.6
  • 44
    • 34147206651 scopus 로고    scopus 로고
    • In vivo efficacy of a novel histone deacetylase inhibitor in combination with radiation for the treatment of gliomas
    • DOI 10.1215/15228517-2006-032
    • Entin-Meer, M.; Yang, X.; VandenBerg, S. R.; Lamborn, K. R.; Nudelman, A.; Rephaeli, A.; et al. (2007). In vivo efficacy of a novel histone deacetylase inhibitor in combination with radiation for the treatment of gliomas. Neuro-oncology, 9, 82-88. (Pubitemid 46580309)
    • (2007) Neuro-Oncology , vol.9 , Issue.2 , pp. 82-88
    • Entin-Meer, M.1    Yang, X.2    VandenBerg, S.R.3    Lamborn, K.R.4    Nudelman, A.5    Rephaeli, A.6    Haas-Kogan, D.A.7
  • 45
    • 0037068312 scopus 로고    scopus 로고
    • CpG island hypermethylation and tumor suppressor genes: A booming present, a brighter future
    • DOI 10.1038/sj.onc.1205600
    • Esteller, M. (2002). CpG island hypermethylation and tumor suppressor genes: a booming present, a brighter future. Oncogene, 21, 5427-5440. (Pubitemid 34983479)
    • (2002) Oncogene , vol.21 , Issue.35 , pp. 5427-5440
    • Esteller, M.1
  • 46
    • 33947315736 scopus 로고    scopus 로고
    • Cancer epigenomics: DNA methylomes and histone-modification maps
    • DOI 10.1038/nrg2005, PII NRG2005
    • Esteller, M. (2007). Cancer epigenomics: DNA methylomes and histone-modification maps. Nature Reviews Genetics, 8, 286-298. (Pubitemid 46439286)
    • (2007) Nature Reviews Genetics , vol.8 , Issue.4 , pp. 286-298
    • Esteller, M.1
  • 50
    • 58049208190 scopus 로고    scopus 로고
    • Genome-wide loss-of-function screen reveals an important role for the proteasome in HDAC inhibitor-induced apoptosis
    • 19111881
    • Fotheringham, S.; Epping, M. T.; Stimson, L.; Khan, O.; Wood, V.; Pezzella, F.; et al. (2009). Genome-wide loss-of-function screen reveals an important role for the proteasome in HDAC inhibitor-induced apoptosis. Cancer Cell, 15, 57-66.
    • (2009) Cancer Cell , vol.15 , pp. 57-66
    • Fotheringham, S.1    Epping, M.T.2    Stimson, L.3    Khan, O.4    Wood, V.5    Pezzella, F.6
  • 51
    • 77955900071 scopus 로고    scopus 로고
    • Pediatric phase i trial and pharmacokinetic study of vorinostat: A Children's Oncology Group phase i consortium report
    • 20606092
    • Fouladi, M.; Park, J. R.; Stewart, C. F.; Gilbertson, R. J.; Schaiquevich, P.; Sun, J.; et al. (2010). Pediatric phase I trial and pharmacokinetic study of vorinostat: a Children's Oncology Group phase I consortium report. Journal of Clinical Oncology, 28, 3623-3629.
    • (2010) Journal of Clinical Oncology , vol.28 , pp. 3623-3629
    • Fouladi, M.1    Park, J.R.2    Stewart, C.F.3    Gilbertson, R.J.4    Schaiquevich, P.5    Sun, J.6
  • 52
    • 84859538161 scopus 로고    scopus 로고
    • Phase II trial of vorinostat in combination with bortezomib in recurrent glioblastoma: A north central cancer treatment group study
    • 22090453
    • Friday, B. B.; Anderson, S. K.; Buckner, J.; Yu, C.; Giannini, C.; Geoffroy, F.; et al. (2012). Phase II trial of vorinostat in combination with bortezomib in recurrent glioblastoma: a north central cancer treatment group study. Neuro-oncology, 14, 215-221.
    • (2012) Neuro-oncology , vol.14 , pp. 215-221
    • Friday, B.B.1    Anderson, S.K.2    Buckner, J.3    Yu, C.4    Giannini, C.5    Geoffroy, F.6
  • 53
    • 0038298289 scopus 로고    scopus 로고
    • Molecular analysis of the rhabdoid predisposition syndrome in a child: A novel germline hSNF5/INI1 mutation and absence of c-myc amplification
    • DOI 10.1023/A:1024345221792
    • Fujisawa, H.; Takabatake, Y.; Fukusato, T.; Tachibana, O.; Tsuchiya, Y.; & Yamashita, J. (2003). Molecular analysis of the rhabdoid predisposition syndrome in a child: A novel germline hSNF5/INI1 mutation and absence of c-myc amplification. Journal of Neuro-oncology, 63, 257-262. (Pubitemid 36874009)
    • (2003) Journal of Neuro-Oncology , vol.63 , Issue.3 , pp. 257-262
    • Fujisawa, H.1    Takabatake, Y.2    Fukusato, T.3    Tachibana, O.4    Tsuchiya, Y.5    Yamashita, J.6
  • 55
    • 33947153003 scopus 로고    scopus 로고
    • Inhibitors of histone deacetylases as potential therapeutic tools for high-risk embryonal tumors of the nervous system of childhood
    • DOI 10.1002/ijc.22401
    • Furchert, S. E.; Lanvers-Kaminsky, C.; Juurgens, H.; Jung, M.; Loidl, A.; & Fruhwald, M. C. (2007). Inhibitors of histone deacetylases as potential therapeutic tools for high-risk embryonal tumors of the nervous system of childhood. International Journal of Cancer, 120, 1787-1794. (Pubitemid 46399367)
    • (2007) International Journal of Cancer , vol.120 , Issue.8 , pp. 1787-1794
    • Furchert, S.E.1    Lanvers-Kaminsky, C.2    Jurgens, H.3    Jung, M.4    Loidl, A.5    Fruhwald, M.C.6
  • 56
    • 65349141942 scopus 로고    scopus 로고
    • Phase II trial of vorinostat in recurrent glioblastoma multiforme: A north central cancer treatment group study
    • 19307505
    • Galanis, E.; Jaeckle, K. A.; Maurer, M. J.; Reid, J. M.; Ames, M. M.; Hardwick, J. S.; et al. (2009). Phase II trial of vorinostat in recurrent glioblastoma multiforme: a north central cancer treatment group study. Journal of Clinical Oncology, 27, 2052-2058.
    • (2009) Journal of Clinical Oncology , vol.27 , pp. 2052-2058
    • Galanis, E.1    Jaeckle, K.A.2    Maurer, M.J.3    Reid, J.M.4    Ames, M.M.5    Hardwick, J.S.6
  • 57
    • 67650756975 scopus 로고    scopus 로고
    • Loss of NECL1, a novel tumor suppressor, can be restored in glioma by HDAC inhibitor-Trichostatin A through Sp1 binding site
    • 19062177
    • Gao, J.; Chen, T.; Liu, J.; Liu, W.; Hu, G.; Guo, X.; et al. (2009). Loss of NECL1, a novel tumor suppressor, can be restored in glioma by HDAC inhibitor-Trichostatin A through Sp1 binding site. Glia, 57, 989-999.
    • (2009) Glia , vol.57 , pp. 989-999
    • Gao, J.1    Chen, T.2    Liu, J.3    Liu, W.4    Hu, G.5    Guo, X.6
  • 58
    • 40449134399 scopus 로고    scopus 로고
    • MiRNAs: Little known mediators of oncogenesis
    • 18295504
    • Gartel, A. L.; & Kandel, E. S. (2008). miRNAs: Little known mediators of oncogenesis. Seminars in Cancer Biology, 18, 103-110.
    • (2008) Seminars in Cancer Biology , vol.18 , pp. 103-110
    • Gartel, A.L.1    Kandel, E.S.2
  • 59
    • 20844444898 scopus 로고    scopus 로고
    • Combination of the histone deacetylase inhibitor LBH589 and the hsp90 inhibitor 17-AAG is highly active against human CML-BC cells and AML cells with activating mutation of FLT-3
    • DOI 10.1182/blood-2004-09-3413
    • George, P.; Bali, P.; Annavarapu, S.; Scuto, A.; Fiskus, W.; Guo, F.; et al. (2005). Combination of the histone deacetylase inhibitor LBH589 and the hsp90 inhibitor 17-AAG is highly active against human CML-BC cells and AML cells with activating mutation of FLT-3. Blood, 105, 1768-1776. (Pubitemid 40223701)
    • (2005) Blood , vol.105 , Issue.4 , pp. 1768-1776
    • George, P.1    Bali, P.2    Annavarapu, S.3    Scuto, A.4    Fiskus, W.5    Guo, F.6    Sigua, C.7    Sondarva, G.8    Moscinski, L.9    Atadja, P.10    Bhalla, K.11
  • 60
    • 77954216767 scopus 로고    scopus 로고
    • Nucleosome occupancy landscape and dynamics at mouse recombination hotspots
    • 20508641
    • Getun, I. V.; Wu, Z. K.; Khalil, A. M.; & Bois, P. R. (2010). Nucleosome occupancy landscape and dynamics at mouse recombination hotspots. EMBO Reports, 11, 555-560.
    • (2010) EMBO Reports , vol.11 , pp. 555-560
    • Getun, I.V.1    Wu, Z.K.2    Khalil, A.M.3    Bois, P.R.4
  • 63
    • 33748067731 scopus 로고    scopus 로고
    • Functional interaction of the retinoblastoma and Ini1/Snf5 tumor suppressors in cell growth and pituitary tumorigenesis
    • DOI 10.1158/0008-5472.CAN-06-1451
    • Guidi, C. J.; Mudhasani, R.; Hoover, K.; Koff, A.; Leav, I.; Imbalzano, A. N.; et al. (2006). Functional interaction of the retinoblastoma and Ini1/Snf5 tumor suppressors in cell growth and pituitary tumorigenesis. Cancer Research, 66, 8076-8082. (Pubitemid 44299173)
    • (2006) Cancer Research , vol.66 , Issue.16 , pp. 8076-8082
    • Guidi, C.J.1    Mudhasani, R.2    Hoover, K.3    Koff, A.4    Leav, I.5    Imbalzano, A.N.6    Jones, S.N.7
  • 64
    • 22744444861 scopus 로고    scopus 로고
    • Epigenetic inactivation of the RASSF1A tumour suppressor gene in ependymoma
    • DOI 10.1016/j.canlet.2004.11.044, PII S0304383504009401
    • Hamilton, D. W.; Lusher, M. E.; Lindsey, J. C.; Ellison, D. W.; & Clifford, S. C. (2005). Epigenetic inactivation of the RASSF1A tumour suppressor gene in ependymoma. Cancer Letters, 227, 75-81. (Pubitemid 41033094)
    • (2005) Cancer Letters , vol.227 , Issue.1 , pp. 75-81
    • Hamilton, D.W.1    Lusher, M.E.2    Lindsey, J.C.3    Ellison, D.W.4    Clifford, S.C.5
  • 67
    • 60149095681 scopus 로고    scopus 로고
    • Regulation of the leucocyte chemoattractant receptor FPR in glioblastoma cells by cell differentiation
    • 19037090
    • Huang, J.; Chen, K.; Gong, W.; Dunlop, N. M.; Howard, O. M.; Bian, X.; et al. (2009). Regulation of the leucocyte chemoattractant receptor FPR in glioblastoma cells by cell differentiation. Carcinogenesis, 30, 348-355.
    • (2009) Carcinogenesis , vol.30 , pp. 348-355
    • Huang, J.1    Chen, K.2    Gong, W.3    Dunlop, N.M.4    Howard, O.M.5    Bian, X.6
  • 68
    • 79958087234 scopus 로고    scopus 로고
    • NBM-HD-3, a novel histone deacetylase inhibitor with anticancer activity through modulation of PTEN and AKT in brain cancer cells
    • 21530633
    • Huang, W. J.; Lin, C. W.; Lee, C. Y.; Chi, L. L.; Chao, Y. C.; Wang, H. N.; et al. (2011). NBM-HD-3, a novel histone deacetylase inhibitor with anticancer activity through modulation of PTEN and AKT in brain cancer cells. Journal of Ethnopharmacology, 136, 156-167.
    • (2011) Journal of Ethnopharmacology , vol.136 , pp. 156-167
    • Huang, W.J.1    Lin, C.W.2    Lee, C.Y.3    Chi, L.L.4    Chao, Y.C.5    Wang, H.N.6
  • 69
    • 33645395297 scopus 로고    scopus 로고
    • High promoter hypermethylation frequency of p14/ARF in supratentorial PNET but not in medulloblastoma
    • 16623784
    • Inda, M. M.; Munoz, J.; Coullin, P.; Fauvet, D.; Danglot, G.; Tunon, T.; et al. (2006). High promoter hypermethylation frequency of p14/ARF in supratentorial PNET but not in medulloblastoma. Histopathology, 48, 579-587.
    • (2006) Histopathology , vol.48 , pp. 579-587
    • Inda, M.M.1    Munoz, J.2    Coullin, P.3    Fauvet, D.4    Danglot, G.5    Tunon, T.6
  • 70
    • 63549132021 scopus 로고    scopus 로고
    • Genomic analysis using high-density single nucleotide polymorphism-based oligonucleotide arrays and multiplex ligation-dependent probe amplification provides a comprehensive analysis of INI1/SMARCB1 in malignant rhabdoid tumors
    • 19276269
    • Jackson, E. M.; Sievert, A. J.; Gai, X.; Hakonarson, H.; Judkins, A. R.; Tooke, L.; et al. (2009). Genomic analysis using high-density single nucleotide polymorphism-based oligonucleotide arrays and multiplex ligation-dependent probe amplification provides a comprehensive analysis of INI1/SMARCB1 in malignant rhabdoid tumors. Clinical Cancer Research, 15, 1923-1930.
    • (2009) Clinical Cancer Research , vol.15 , pp. 1923-1930
    • Jackson, E.M.1    Sievert, A.J.2    Gai, X.3    Hakonarson, H.4    Judkins, A.R.5    Tooke, L.6
  • 71
    • 70349329440 scopus 로고    scopus 로고
    • Abrogation of mitogen-activated protein kinase and Akt signaling by vandetanib synergistically potentiates histone deacetylase inhibitor-induced apoptosis in human glioma cells
    • 19622715
    • Jane, E. P.; Premkumar, D. R.; Addo-Yobo, S. O.; & Pollack, I. F. (2009). Abrogation of mitogen-activated protein kinase and Akt signaling by vandetanib synergistically potentiates histone deacetylase inhibitor-induced apoptosis in human glioma cells. The Journal of Pharmacology and Experimental Therapeutics, 331, 327-337.
    • (2009) The Journal of Pharmacology and Experimental Therapeutics , vol.331 , pp. 327-337
    • Jane, E.P.1    Premkumar, D.R.2    Addo-Yobo, S.O.3    Pollack, I.F.4
  • 72
    • 0036527775 scopus 로고    scopus 로고
    • Histone-deacetylase inhibitors: Novel drugs for the treatment of cancer
    • Johnstone, R. W. (2002). Histone-deacetylase inhibitors: novel drugs for the treatment of cancer. Nature Reviews Drug Discovery, 1, 287-299. (Pubitemid 37361445)
    • (2002) Nature Reviews Drug Discovery , vol.1 , Issue.4 , pp. 287-299
    • Johnstone, R.W.1
  • 73
    • 38549125699 scopus 로고    scopus 로고
    • Gene silencing of TSPYL5 mediated by aberrant promoter methylation in gastric cancers
    • DOI 10.1038/labinvest.3700706, PII 3700706
    • Jung, Y.; Park, J.; Bang, Y. J.; & Kim, T. Y. (2008). Gene silencing of TSPYL5 mediated by aberrant promoter methylation in gastric cancers. Laboratory Investigation, 88, 153-160. (Pubitemid 351161273)
    • (2008) Laboratory Investigation , vol.88 , Issue.2 , pp. 153-160
    • Jung, Y.1    Park, J.2    Bang, Y.-J.3    Kim, T.-Y.4
  • 74
    • 84855471990 scopus 로고    scopus 로고
    • HDAC inhibitors in cancer biology: Emerging mechanisms and clinical applications
    • 22124371
    • Khan, O.; & La Thangue, N. B. (2012). HDAC inhibitors in cancer biology: Emerging mechanisms and clinical applications. Immunology and Cell Biology, 90, 85-94.
    • (2012) Immunology and Cell Biology , vol.90 , pp. 85-94
    • Khan, O.1    La Thangue, N.B.2
  • 75
    • 33747889966 scopus 로고    scopus 로고
    • Epigenomic profiling reveals novel and frequent targets of aberrant DNA methylation-mediated silencing in malignant glioma
    • DOI 10.1158/0008-5472.CAN-05-4552
    • Kim, T. Y.; Zhong, S.; Fields, C. R.; Kim, J. H.; & Robertson, K. D. (2006). Epigenomic profiling reveals novel and frequent targets of aberrant DNA methylation-mediated silencing in malignant glioma. Cancer Research, 66, 7490-7501. (Pubitemid 44289203)
    • (2006) Cancer Research , vol.66 , Issue.15 , pp. 7490-7501
    • Kim, T.-Y.1    Zhong, S.2    Fields, C.R.3    Kim, J.H.4    Robertson, K.D.5
  • 76
    • 1642391063 scopus 로고    scopus 로고
    • Hypermethylation and transcriptional downregulation of the carboxyl-terminal modulator protein gene in glioblastomas
    • Knobbe, C. B.; Reifenberger, J.; Blaschke, B.; & Reifenberger, G. (2004). Hypermethylation and transcriptional downregulation of the carboxyl-terminal modulator protein gene in glioblastomas. Journal of the National Cancer Institute, 96, 483-486. (Pubitemid 38443652)
    • (2004) Journal of the National Cancer Institute , vol.96 , Issue.6 , pp. 483-486
    • Knobbe, C.B.1    Reifenberger, J.2    Blaschke, B.3    Reifenberger, G.4
  • 78
    • 57149094865 scopus 로고    scopus 로고
    • An epigenetic genome-wide screen identifies SPINT2 as a novel tumor suppressor gene in pediatric medulloblastoma
    • 19047176
    • Kongkham, P. N.; Northcott, P. A.; Ra, Y. S.; Nakahara, Y.; Mainprize, T. G.; Croul, S. E.; et al. (2008). An epigenetic genome-wide screen identifies SPINT2 as a novel tumor suppressor gene in pediatric medulloblastoma. Cancer Research, 68, 9945-9953.
    • (2008) Cancer Research , vol.68 , pp. 9945-9953
    • Kongkham, P.N.1    Northcott, P.A.2    Ra, Y.S.3    Nakahara, Y.4    Mainprize, T.G.5    Croul, S.E.6
  • 79
    • 77952671657 scopus 로고    scopus 로고
    • The SFRP family of WNT inhibitors function as novel tumor suppressor genes epigenetically silenced in medulloblastoma
    • 20208569
    • Kongkham, P. N.; Northcott, P. A.; Croul, S. E.; Smith, C. A.; Taylor, M. D.; & Rutka, J. T. (2010). The SFRP family of WNT inhibitors function as novel tumor suppressor genes epigenetically silenced in medulloblastoma. Oncogene, 29, 3017-3024.
    • (2010) Oncogene , vol.29 , pp. 3017-3024
    • Kongkham, P.N.1    Northcott, P.A.2    Croul, S.E.3    Smith, C.A.4    Taylor, M.D.5    Rutka, J.T.6
  • 80
    • 36849077136 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors induce cell death in supratentorial primitive neuroectodermal tumor cells
    • 17016591
    • Kumar, K. S.; Sonnemann, J.; & Beck, J. F. (2006). Histone deacetylase inhibitors induce cell death in supratentorial primitive neuroectodermal tumor cells. Oncology Reports, 16, 1047-1052.
    • (2006) Oncology Reports , vol.16 , pp. 1047-1052
    • Kumar, K.S.1    Sonnemann, J.2    Beck, J.F.3
  • 85
    • 0035839135 scopus 로고    scopus 로고
    • Snf1 - A histone kinase that works in concert with the histone acetyltransferase Gcn5 to regulate transcription
    • DOI 10.1126/science.1062322
    • Lo, W. S.; Duggan, L.; Emre, N. C.; Belotserkovskya, R.; Lane, W. S.; Shiekhattar, R.; et al. (2001). Snf1-a histone kinase that works in concert with the histone acetyltransferase Gcn5 to regulate transcription. Science, 293, 1142-1146. (Pubitemid 32758096)
    • (2001) Science , vol.293 , Issue.5532 , pp. 1142-1146
    • Lo, W.-S.1    Duggan, L.2    Emre, N.C.T.3    Belotserkovskya, R.4    Lane, W.S.5    Shiekhattar, R.6    Berger, S.L.7
  • 87
  • 88
    • 52249090461 scopus 로고    scopus 로고
    • Differential expression of 12 histone deacetylase (HDAC) genes in astrocytomas and normal brain tissue: Class II and IV are hypoexpressed in glioblastomas
    • 18713462
    • Lucio-Eterovic, A. K.; Cortez, M. A.; Valera, E. T.; Motta, F. J.; Queiroz, R. G.; Machado, H. R.; et al. (2008). Differential expression of 12 histone deacetylase (HDAC) genes in astrocytomas and normal brain tissue: class II and IV are hypoexpressed in glioblastomas. BMC Cancer, 8, 243.
    • (2008) BMC Cancer , vol.8 , pp. 243
    • Lucio-Eterovic, A.K.1    Cortez, M.A.2    Valera, E.T.3    Motta, F.J.4    Queiroz, R.G.5    Machado, H.R.6
  • 91
    • 77952888433 scopus 로고    scopus 로고
    • The DNA methylome of glioblastoma multiforme
    • 20064612
    • Martinez, R.; & Esteller, M. (2010). The DNA methylome of glioblastoma multiforme. Neurobiology of Disease, 39, 40-46.
    • (2010) Neurobiology of Disease , vol.39 , pp. 40-46
    • Martinez, R.1    Esteller, M.2
  • 93
    • 33646419301 scopus 로고    scopus 로고
    • The SHREW1 gene, frequently deleted in oligodendrogliomas, functions to inhibit cell adhesion and migration
    • McDonald, J. M.; Dunlap, S.; Cogdell, D.; Dunmire, V.; Wei, Q.; Starzinski-Powitz, A.; et al. (2006). The SHREW1 gene, frequently deleted in oligodendrogliomas, functions to inhibit cell adhesion and migration. Cancer Biology & Therapy, 5, 300-304.
    • (2006) Cancer Biology & Therapy , vol.5 , pp. 300-304
    • McDonald, J.M.1    Dunlap, S.2    Cogdell, D.3    Dunmire, V.4    Wei, Q.5    Starzinski-Powitz, A.6
  • 94
    • 34250643993 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors: Biology and mechanism of action
    • 17464243
    • Mehnert, J. M.; & Kelly, W. K. (2007). Histone deacetylase inhibitors: biology and mechanism of action. The Cancer Journal, 13, 23-29.
    • (2007) The Cancer Journal , vol.13 , pp. 23-29
    • Mehnert, J.M.1    Kelly, W.K.2
  • 95
    • 49649125042 scopus 로고    scopus 로고
    • Genome-scale DNA methylation maps of pluripotent and differentiated cells
    • 18600261
    • Meissner, A.; Mikkelsen, T. S.; Gu, H.; Wernig, M.; Hanna, J.; Sivachenko, A.; et al. (2008). Genome-scale DNA methylation maps of pluripotent and differentiated cells. Nature, 454, 766-770.
    • (2008) Nature , vol.454 , pp. 766-770
    • Meissner, A.1    Mikkelsen, T.S.2    Gu, H.3    Wernig, M.4    Hanna, J.5    Sivachenko, A.6
  • 96
    • 33645988574 scopus 로고    scopus 로고
    • Methylation of RASSF1A and TRAIL pathway-related genes is frequent in childhood intracranial ependymomas and benign choroid plexus papilloma
    • 16616114
    • Michalowski, M. B.; de Fraipont, F.; Michelland, S.; Entz-Werle, N.; Grill, J.; Pasquier, B.; et al. (2006). Methylation of RASSF1A and TRAIL pathway-related genes is frequent in childhood intracranial ependymomas and benign choroid plexus papilloma. Cancer Genetics and Cytogenetics, 166, 74-81.
    • (2006) Cancer Genetics and Cytogenetics , vol.166 , pp. 74-81
    • Michalowski, M.B.1    De Fraipont, F.2    Michelland, S.3    Entz-Werle, N.4    Grill, J.5    Pasquier, B.6
  • 97
    • 77953723856 scopus 로고    scopus 로고
    • HDAC5 and HDAC9 in medulloblastoma: Novel markers for risk stratification and role in tumor cell growth
    • 20413433
    • Milde, T.; Oehme, I.; Korshunov, A.; Kopp-Schneider, A.; Remke, M.; Northcott, P.; et al. (2010). HDAC5 and HDAC9 in medulloblastoma: novel markers for risk stratification and role in tumor cell growth. Clinical Cancer Research, 16, 3240-3252.
    • (2010) Clinical Cancer Research , vol.16 , pp. 3240-3252
    • Milde, T.1    Oehme, I.2    Korshunov, A.3    Kopp-Schneider, A.4    Remke, M.5    Northcott, P.6
  • 98
    • 30344477367 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer
    • DOI 10.1038/nrc1779
    • Minucci, S.; & Pelicci, P. G. (2006). Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer. Nature Reviews Cancer, 6, 38-51. (Pubitemid 43054973)
    • (2006) Nature Reviews Cancer , vol.6 , Issue.1 , pp. 38-51
    • Minucci, S.1    Pelicci, P.G.2
  • 99
    • 51049090194 scopus 로고    scopus 로고
    • Antitumor activity of histone deacetylase inhibitors in non-small cell lung cancer cells: Development of a molecular predictive model
    • 18606719
    • Miyanaga, A.; Gemma, A.; Noro, R.; Kataoka, K.; Matsuda, K.; Nara, M.; et al. (2008). Antitumor activity of histone deacetylase inhibitors in non-small cell lung cancer cells: development of a molecular predictive model. Molecular Cancer Therapeutics, 7, 1923-1930.
    • (2008) Molecular Cancer Therapeutics , vol.7 , pp. 1923-1930
    • Miyanaga, A.1    Gemma, A.2    Noro, R.3    Kataoka, K.4    Matsuda, K.5    Nara, M.6
  • 100
    • 58249096131 scopus 로고    scopus 로고
    • HDAC4 represses p21(WAF1/Cip1) expression in human cancer cells through a Sp1-dependent, p53-independent mechanism
    • 18850004
    • Mottet, D.; Pirotte, S.; Lamour, V.; Hagedorn, M.; Javerzat, S.; Bikfalvi, A.; et al. (2009). HDAC4 represses p21(WAF1/Cip1) expression in human cancer cells through a Sp1-dependent, p53-independent mechanism. Oncogene, 28, 243-256.
    • (2009) Oncogene , vol.28 , pp. 243-256
    • Mottet, D.1    Pirotte, S.2    Lamour, V.3    Hagedorn, M.4    Javerzat, S.5    Bikfalvi, A.6
  • 101
    • 0028947217 scopus 로고
    • A human protein with homology to Saccharomyces cerevisiae SNF5 interacts with the potential helicase hbrm
    • 7739891
    • Muchardt, C.; Sardet, C.; Bourachot, B.; Onufryk, C.; & Yaniv, M. (1995). A human protein with homology to Saccharomyces cerevisiae SNF5 interacts with the potential helicase hbrm. Nucleic Acids Research, 23, 1127-1132.
    • (1995) Nucleic Acids Research , vol.23 , pp. 1127-1132
    • Muchardt, C.1    Sardet, C.2    Bourachot, B.3    Onufryk, C.4    Yaniv, M.5
  • 103
    • 77957339220 scopus 로고    scopus 로고
    • Interplay between different epigenetic modifications and mechanisms
    • 20920747
    • Murr, R. (2010). Interplay between different epigenetic modifications and mechanisms. Advances in Genetics, 70, 101-141.
    • (2010) Advances in Genetics , vol.70 , pp. 101-141
    • Murr, R.1
  • 104
    • 67649090559 scopus 로고    scopus 로고
    • Molecular epigenetics and genetics in neuro-oncology
    • 19560734
    • Nagarajan, R. P.; & Costello, J. F. (2009). Molecular epigenetics and genetics in neuro-oncology. Neurotherapeutics, 6, 436-446.
    • (2009) Neurotherapeutics , vol.6 , pp. 436-446
    • Nagarajan, R.P.1    Costello, J.F.2
  • 105
    • 73949114835 scopus 로고    scopus 로고
    • Genetic and epigenetic inactivation of Kruppel-like factor 4 in medulloblastoma
    • 20072650
    • Nakahara, Y.; Northcott, P. A.; Li, M.; Kongkham, P. N.; Smith, C.; Yan, H.; et al. (2010). Genetic and epigenetic inactivation of Kruppel-like factor 4 in medulloblastoma. Neoplasia, 12, 20-27.
    • (2010) Neoplasia , vol.12 , pp. 20-27
    • Nakahara, Y.1    Northcott, P.A.2    Li, M.3    Kongkham, P.N.4    Smith, C.5    Yan, H.6
  • 106
    • 0035815360 scopus 로고    scopus 로고
    • Role of histone H3 lysine 9 methylation in epigenetic control of heterochromatin assembly
    • DOI 10.1126/science.1060118
    • Nakayama, J.; Rice, J. C.; Strahl, B. D.; Allis, C. D.; & Grewal, S. I. (2001). Role of histone H3 lysine 9 methylation in epigenetic control of heterochromatin assembly. Science, 292, 110-113. (Pubitemid 32289138)
    • (2001) Science , vol.292 , Issue.5514 , pp. 110-113
    • Nakayama, J.1    Rice, J.C.2    Strahl, B.D.3    Allis, C.D.4    Grewal, S.I.S.5
  • 107
    • 84866554223 scopus 로고    scopus 로고
    • Role of microRNAs in gliomagenesis: Targeting miRNAs in glioblastoma multiforme therapy
    • Nikaki, A.; Piperi, C.; & Papavassiliou, A. G. (2012). Role of microRNAs in gliomagenesis: targeting miRNAs in glioblastoma multiforme therapy. Expert Opinion on Investigational Drugs, 21, 1475-1488.
    • (2012) Expert Opinion on Investigational Drugs , vol.21 , pp. 1475-1488
    • Nikaki, A.1    Piperi, C.2    Papavassiliou . A, G.3
  • 108
    • 63449115501 scopus 로고    scopus 로고
    • Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma
    • 19270706
    • Northcott, P. A.; Nakahara, Y.; Wu, X.; Feuk, L.; Ellison, D. W.; Croul, S.; et al. (2009). Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma. Nature Genetics, 41, 465-472.
    • (2009) Nature Genetics , vol.41 , pp. 465-472
    • Northcott, P.A.1    Nakahara, Y.2    Wu, X.3    Feuk, L.4    Ellison, D.W.5    Croul, S.6
  • 109
    • 80655132137 scopus 로고    scopus 로고
    • SOX2-RNAi attenuates S-phase entry and induces RhoA-dependent switch to protease-independent amoeboid migration in human glioma cells
    • 22070920
    • Oppel, F.; Muller, N.; Schackert, G.; Hendruschk, S.; Martin, D.; Geiger, K. D.; et al. (2011). SOX2-RNAi attenuates S-phase entry and induces RhoA-dependent switch to protease-independent amoeboid migration in human glioma cells. Molecular Cancer, 10, 137.
    • (2011) Molecular Cancer , vol.10 , pp. 137
    • Oppel, F.1    Muller, N.2    Schackert, G.3    Hendruschk, S.4    Martin, D.5    Geiger, K.D.6
  • 110
    • 67349149403 scopus 로고    scopus 로고
    • Analysis of the matrix metalloproteinase family reveals that MMP8 is often mutated in melanoma
    • 19330028
    • Palavalli, L. H.; Prickett, T. D.; Wunderlich, J. R.; Wei, X.; Burrell, A. S.; Porter-Gill, P.; et al. (2009). Analysis of the matrix metalloproteinase family reveals that MMP8 is often mutated in melanoma. Nature Genetics, 41, 518-520.
    • (2009) Nature Genetics , vol.41 , pp. 518-520
    • Palavalli, L.H.1    Prickett, T.D.2    Wunderlich, J.R.3    Wei, X.4    Burrell, A.S.5    Porter-Gill, P.6
  • 111
    • 13444261160 scopus 로고    scopus 로고
    • Epigenetic inactivation of DLC-1 in supratentorial primitive neuroectodermal tumor
    • DOI 10.1016/j.humpath.2004.09.021
    • Pang, J. C.; Chang, Q.; Chung, Y. F.; Teo, J. G.; Poon, W. S.; Zhou, L. F.; et al. (2005). Epigenetic inactivation of DLC-1 in supratentorial primitive neuroectodermal tumor. Human Pathology, 36, 36-43. (Pubitemid 40215632)
    • (2005) Human Pathology , vol.36 , Issue.1 , pp. 36-43
    • Pang, J.C.-S.1    Chang, Q.2    Chung, Y.F.3    Teo, J.G.C.4    Poon, W.S.5    Zhou, L.-F.6    Kong, X.7    Ng, H.-K.8
  • 112
    • 78449275473 scopus 로고    scopus 로고
    • KIAA0495/PDAM is frequently downregulated in oligodendroglial tumors and its knockdown by siRNA induces cisplatin resistance in glioma cells
    • 20477830
    • Pang, J. C.; Li, K. K.; Lau, K. M.; Ng, Y. L.; Wong, J.; Chung, N. Y.; et al. (2010). KIAA0495/PDAM is frequently downregulated in oligodendroglial tumors and its knockdown by siRNA induces cisplatin resistance in glioma cells. Brain Pathology, 20, 1021-1032.
    • (2010) Brain Pathology , vol.20 , pp. 1021-1032
    • Pang, J.C.1    Li, K.K.2    Lau, K.M.3    Ng, Y.L.4    Wong, J.5    Chung, N.Y.6
  • 113
    • 77950543254 scopus 로고    scopus 로고
    • Epigenetic modifiers as anticancer drugs: Effectiveness of valproic acid in neural crest-derived tumor cells
    • 20332466
    • Papi, A.; Ferreri, A. M.; Rocchi, P.; Guerra, F.; & Orlandi, M. (2010). Epigenetic modifiers as anticancer drugs: effectiveness of valproic acid in neural crest-derived tumor cells. Anticancer Research, 30, 535-540.
    • (2010) Anticancer Research , vol.30 , pp. 535-540
    • Papi, A.1    Ferreri, A.M.2    Rocchi, P.3    Guerra, F.4    Orlandi, M.5
  • 114
    • 52949127312 scopus 로고    scopus 로고
    • An integrated genomic analysis of human glioblastoma multiforme
    • 18772396
    • Parsons, D. W.; Jones, S.; Zhang, X.; Lin, J. C.; Leary, R. J.; Angenendt, P.; et al. (2008). An integrated genomic analysis of human glioblastoma multiforme. Science, 321, 1807-1812.
    • (2008) Science , vol.321 , pp. 1807-1812
    • Parsons, D.W.1    Jones, S.2    Zhang, X.3    Lin, J.C.4    Leary, R.J.5    Angenendt, P.6
  • 115
    • 79251629946 scopus 로고    scopus 로고
    • The genetic landscape of the childhood cancer medulloblastoma
    • 21163964
    • Parsons, D. W.; Li, M.; Zhang, X.; Jones, S.; Leary, R. J.; Lin, J. C.; et al. (2011). The genetic landscape of the childhood cancer medulloblastoma. Science, 331, 435-439.
    • (2011) Science , vol.331 , pp. 435-439
    • Parsons, D.W.1    Li, M.2    Zhang, X.3    Jones, S.4    Leary, R.J.5    Lin, J.C.6
  • 116
    • 77958536805 scopus 로고    scopus 로고
    • Portrait of ependymoma recurrence in children: Biomarkers of tumor progression identified by dual-color microarray-based gene expression analysis
    • 20885975
    • Peyre, M.; Commo, F.; Dantas-Barbosa, C.; Andreiuolo, F.; Puget, S.; Lacroix, L.; et al. (2010). Portrait of ependymoma recurrence in children: biomarkers of tumor progression identified by dual-color microarray-based gene expression analysis. PLoS ONE, 5, e12932.
    • (2010) PLoS ONE , vol.5 , pp. 12932
    • Peyre, M.1    Commo, F.2    Dantas-Barbosa, C.3    Andreiuolo, F.4    Puget, S.5    Lacroix, L.6
  • 117
    • 34249850353 scopus 로고    scopus 로고
    • Array-based profiling of reference-independent methylation status (aPRIMES) identifies frequent promoter methylation and consecutive downregulation of ZIC2 in pediatric medulloblastoma
    • 17344319
    • Pfister, S.; Schlaeger, C.; Mendrzyk, F.; Wittmann, A.; Benner, A.; Kulozik, A.; et al. (2007). Array-based profiling of reference-independent methylation status (aPRIMES) identifies frequent promoter methylation and consecutive downregulation of ZIC2 in pediatric medulloblastoma. Nucleic Acids Research, 35, e51.
    • (2007) Nucleic Acids Research , vol.35 , pp. 51
    • Pfister, S.1    Schlaeger, C.2    Mendrzyk, F.3    Wittmann, A.4    Benner, A.5    Kulozik, A.6
  • 119
    • 73949090337 scopus 로고    scopus 로고
    • High incidence of MGMT and RARbeta promoter methylation in primary glioblastomas: Association with histopathological characteristics, inflammatory mediators and clinical outcome
    • 19809523
    • Piperi, C.; Themistocleous, M. S.; Papavassiliou, G. A.; Farmaki, E.; Levidou, G.; Korkolopoulou, P.; et al. (2010). High incidence of MGMT and RARbeta promoter methylation in primary glioblastomas: association with histopathological characteristics, inflammatory mediators and clinical outcome. Molecular Medicine, 16, 1-9.
    • (2010) Molecular Medicine , vol.16 , pp. 1-9
    • Piperi, C.1    Themistocleous, M.S.2    Papavassiliou, G.A.3    Farmaki, E.4    Levidou, G.5    Korkolopoulou, P.6
  • 120
    • 77957970301 scopus 로고    scopus 로고
    • Epigenetic modifications and human disease
    • 20944598
    • Portela, A.; & Esteller, M. (2010). Epigenetic modifications and human disease. Nature Biotechnology, 28, 1057-1068.
    • (2010) Nature Biotechnology , vol.28 , pp. 1057-1068
    • Portela, A.1    Esteller, M.2
  • 121
    • 79951684725 scopus 로고    scopus 로고
    • Marizomib, a proteasome inhibitor for all seasons: Preclinical profile and a framework for clinical trials
    • Potts, C. B.; Albitar, X. M.; Anderson, C. K.; Baritaki, S.; Berkers, C.; Bonavida, B.; et al. (2011a). Marizomib, a proteasome inhibitor for all seasons: preclinical profile and a framework for clinical trials. Current Cancer Drug Targets, 11, 254-284.
    • (2011) Current Cancer Drug Targets , vol.11 , pp. 254-284
    • Potts, C.B.1    Albitar, X.M.2    Anderson, C.K.3    Baritaki, S.4    Berkers, C.5    Bonavida, B.6
  • 122
    • 80052767861 scopus 로고    scopus 로고
    • CHD5, a brain-specific paralog of Mi2 chromatin remodeling enzymes, regulates expression of neuronal genes
    • 21931736
    • Potts, R. C.; Zhang, P.; Wurster, A. L.; Precht, P.; Mughal, M. R.; Wood, W. H.; 3rd, et al. (2011b). CHD5, a brain-specific paralog of Mi2 chromatin remodeling enzymes, regulates expression of neuronal genes. PLoS ONE, 6, e24515.
    • (2011) PLoS ONE , vol.6 , pp. 24515
    • Potts, R.C.1    Zhang, P.2    Wurster, A.L.3    Precht, P.4    Mughal, M.R.5    Wood III, W.H.6
  • 123
    • 84872601365 scopus 로고    scopus 로고
    • Bortezomib-induced sensitization of malignant human glioma cells to vorinostat-induced apoptosis depends on reactive oxygen species production, mitochondrial dysfunction, Noxa upregulation, Mcl-1 cleavage, and DNA damage
    • 10.1002/mc.21835
    • Premkumar, D. R.; Jane, E. P.; Agostino, N. R.; Didomenico, J. D.; & Pollack, I. F. (2011). Bortezomib-induced sensitization of malignant human glioma cells to vorinostat-induced apoptosis depends on reactive oxygen species production, mitochondrial dysfunction, Noxa upregulation, Mcl-1 cleavage, and DNA damage. Molecular Carcinogenesis,. doi: 10.1002/mc.21835.
    • (2011) Molecular Carcinogenesis
    • Premkumar, D.R.1    Jane, E.P.2    Agostino, N.R.3    Didomenico, J.D.4    Pollack, I.F.5
  • 124
    • 79951910702 scopus 로고    scopus 로고
    • Phase i study of vorinostat in patients with advanced solid tumors and hepatic dysfunction: A National Cancer Institute Organ Dysfunction Working Group study
    • 20837947
    • Ramalingam, S. S.; Kummar, S.; Sarantopoulos, J.; Shibata, S.; LoRusso, P.; Yerk, M.; et al. (2010). Phase I study of vorinostat in patients with advanced solid tumors and hepatic dysfunction: a National Cancer Institute Organ Dysfunction Working Group study. Journal of Clinical Oncology, 28, 4507-4512.
    • (2010) Journal of Clinical Oncology , vol.28 , pp. 4507-4512
    • Ramalingam, S.S.1    Kummar, S.2    Sarantopoulos, J.3    Shibata, S.4    Lorusso, P.5    Yerk, M.6
  • 126
    • 79951661556 scopus 로고    scopus 로고
    • Epigenetic regulation of glial fibrillary acidic protein by DNA methylation in human malignant gliomas
    • 21075782
    • Restrepo, A.; Smith, C. A.; Agnihotri, S.; Shekarforoush, M.; Kongkham, P. N.; Seol, H. J.; et al. (2011). Epigenetic regulation of glial fibrillary acidic protein by DNA methylation in human malignant gliomas. Neuro-oncology, 13, 42-50.
    • (2011) Neuro-oncology , vol.13 , pp. 42-50
    • Restrepo, A.1    Smith, C.A.2    Agnihotri, S.3    Shekarforoush, M.4    Kongkham, P.N.5    Seol, H.J.6
  • 130
    • 0028264312 scopus 로고
    • Effects of antisense glial fibrillary acidic protein complementary DNA on the growth, invasion, and adhesion of human astrocytoma cells
    • Rutka, J. T.; Hubbard, S. L.; Fukuyama, K.; Matsuzawa, K.; Dirks, P. B.; & Becker, L. E. (1994). Effects of antisense glial fibrillary acidic protein complementary DNA on the growth, invasion, and adhesion of human astrocytoma cells. Cancer Research, 54, 3267-3272. (Pubitemid 24208940)
    • (1994) Cancer Research , vol.54 , Issue.12 , pp. 3267-3272
    • Rutka, J.T.1    Hubbard, S.L.2    Fukuyama, K.3    Matsuzawa, K.4    Dirks, P.B.5    Becker, L.E.6
  • 132
    • 77956059770 scopus 로고    scopus 로고
    • Vorinostat enhances the cytotoxic effects of the topoisomerase i inhibitor SN38 in glioblastoma cell lines
    • 20135194
    • Sarcar, B.; Kahali, S.; & Chinnaiyan, P. (2010). Vorinostat enhances the cytotoxic effects of the topoisomerase I inhibitor SN38 in glioblastoma cell lines. Journal of Neuro-oncology, 99, 201-207.
    • (2010) Journal of Neuro-oncology , vol.99 , pp. 201-207
    • Sarcar, B.1    Kahali, S.2    Chinnaiyan, P.3
  • 134
    • 83555173277 scopus 로고    scopus 로고
    • DNA hypermethylation and histone modifications downregulate the candidate tumor suppressor gene RRP22 on 22q12 in human gliomas
    • 21631628
    • Schmidt, N.; Windmann, S.; Reifenberger, G.; & Riemenschneider, M. J. (2012). DNA hypermethylation and histone modifications downregulate the candidate tumor suppressor gene RRP22 on 22q12 in human gliomas. Brain Pathology, 22, 17-25.
    • (2012) Brain Pathology , vol.22 , pp. 17-25
    • Schmidt, N.1    Windmann, S.2    Reifenberger, G.3    Riemenschneider, M.J.4
  • 136
    • 76049106059 scopus 로고    scopus 로고
    • Germline nonsense mutation and somatic inactivation of SMARCA4/BRG1 in a family with rhabdoid tumor predisposition syndrome
    • 20137775
    • Schneppenheim, R.; Fruhwald, M. C.; Gesk, S.; Hasselblatt, M.; Jeibmann, A.; Kordes, U.; et al. (2010). Germline nonsense mutation and somatic inactivation of SMARCA4/BRG1 in a family with rhabdoid tumor predisposition syndrome. American Journal of Human Genetics, 86, 279-284.
    • (2010) American Journal of Human Genetics , vol.86 , pp. 279-284
    • Schneppenheim, R.1    Fruhwald, M.C.2    Gesk, S.3    Hasselblatt, M.4    Jeibmann, A.5    Kordes, U.6
  • 137
    • 0141794252 scopus 로고    scopus 로고
    • Differential expression of bikunin (HAI-2/PB), a proposed mediator of glioma invasion, by demethylation treatment
    • DOI 10.1023/A:1025674227750
    • Schuster, J. M.; Longo, M.; & Nelson, P. S. (2003). Differential expression of bikunin (HAI-2/PB), a proposed mediator of glioma invasion, by demethylation treatment. Journal of Neuro-oncology, 64, 219-225. (Pubitemid 37203462)
    • (2003) Journal of Neuro-Oncology , vol.64 , Issue.3 , pp. 219-225
    • Schuster, J.M.1    Longo, M.2    Nelson, P.S.3
  • 138
    • 84862777348 scopus 로고    scopus 로고
    • Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma
    • 22286061
    • Schwartzentruber, J.; Korshunov, A.; Liu, X. Y.; Jones, D. T.; Pfaff, E.; Jacob, K.; et al. (2012). Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma. Nature, 482, 226-231.
    • (2012) Nature , vol.482 , pp. 226-231
    • Schwartzentruber, J.1    Korshunov, A.2    Liu, X.Y.3    Jones, D.T.4    Pfaff, E.5    Jacob, K.6
  • 139
    • 21744457108 scopus 로고    scopus 로고
    • Global histone modification patterns predict risk of prostate cancer recurrence
    • DOI 10.1038/nature03672
    • Seligson, D. B.; Horvath, S.; Shi, T.; Yu, H.; Tze, S.; Grunstein, M.; et al. (2005). Global histone modification patterns predict risk of prostate cancer recurrence. Nature, 435, 1262-1266. (Pubitemid 40943093)
    • (2005) Nature , vol.435 , Issue.7046 , pp. 1262-1266
    • Seligson, D.B.1    Horvath, S.2    Shi, T.3    Yu, H.4    Tze, S.5    Grunstein, M.6    Kurdistani, S.K.7
  • 143
    • 0037075204 scopus 로고    scopus 로고
    • Preferential loss of Death Associated Protein kinase expression in invasive pituitary tumours is associated with either CPG island methylation or homozygous deletion
    • DOI 10.1038/sj/onc/1205195
    • Simpson, D. J.; Clayton, R. N.; & Farrell, W. E. (2002). Preferential loss of Death Associated Protein kinase expression in invasive pituitary tumours is associated with either CpG island methylation or homozygous deletion. Oncogene, 21, 1217-1224. (Pubitemid 34185238)
    • (2002) Oncogene , vol.21 , Issue.8 , pp. 1217-1224
    • Simpson, D.J.1    Clayton, R.N.2    Farrell, W.E.3
  • 144
    • 80052743686 scopus 로고    scopus 로고
    • Inhibition of LSD1 sensitizes glioblastoma cells to histone deacetylase inhibitors
    • 21653597
    • Singh, M. M.; Manton, C. A.; Bhat, K. P.; Tsai, W. W.; Aldape, K.; Barton, M. C.; et al. (2011). Inhibition of LSD1 sensitizes glioblastoma cells to histone deacetylase inhibitors. Neuro-oncology, 13, 894-903.
    • (2011) Neuro-oncology , vol.13 , pp. 894-903
    • Singh, M.M.1    Manton, C.A.2    Bhat, K.P.3    Tsai, W.W.4    Aldape, K.5    Barton, M.C.6
  • 145
    • 79957568143 scopus 로고    scopus 로고
    • MiR-101 is down-regulated in glioblastoma resulting in EZH2-induced proliferation, migration, and angiogenesis
    • 21321380
    • Smits, M.; Nilsson, J.; Mir, S. E.; van der Stoop, P. M.; Hulleman, E.; Niers, J. M.; et al. (2010). miR-101 is down-regulated in glioblastoma resulting in EZH2-induced proliferation, migration, and angiogenesis. Oncotarget, 1, 710-720.
    • (2010) Oncotarget , vol.1 , pp. 710-720
    • Smits, M.1    Nilsson, J.2    Mir, S.E.3    Van Der Stoop, P.M.4    Hulleman, E.5    Niers, J.M.6
  • 146
    • 41549151359 scopus 로고    scopus 로고
    • Response of preclinical medulloblastoma models to combination therapy with 13-cis retinoic acid and suberoylanilide hydroxamic acid (SAHA)
    • 18060600
    • Spiller, S. E.; Ditzler, S. H.; Pullar, B. J.; & Olson, J. M. (2008). Response of preclinical medulloblastoma models to combination therapy with 13-cis retinoic acid and suberoylanilide hydroxamic acid (SAHA). Journal of Neuro-oncology, 87, 133-141.
    • (2008) Journal of Neuro-oncology , vol.87 , pp. 133-141
    • Spiller, S.E.1    Ditzler, S.H.2    Pullar, B.J.3    Olson, J.M.4
  • 148
    • 84856556018 scopus 로고    scopus 로고
    • The histone deacetylase inhibitor butyroyloxymethyl diethylphosphate (AN-7) protects normal cells against toxicity of anticancer agents while augmenting their anticancer activity
    • 20862515
    • Tarasenko, N.; Kessler-Icekson, G.; Boer, P.; Inbal, A.; Schlesinger, H.; Phillips, D. R.; et al. (2012). The histone deacetylase inhibitor butyroyloxymethyl diethylphosphate (AN-7) protects normal cells against toxicity of anticancer agents while augmenting their anticancer activity. Investigational New Drugs, 30, 130-143.
    • (2012) Investigational New Drugs , vol.30 , pp. 130-143
    • Tarasenko, N.1    Kessler-Icekson, G.2    Boer, P.3    Inbal, A.4    Schlesinger, H.5    Phillips, D.R.6
  • 149
    • 78650154699 scopus 로고    scopus 로고
    • Neuralized1 causes apoptosis and downregulates Notch target genes in medulloblastoma
    • 20847082
    • Teider, N.; Scott, D. K.; Neiss, A.; Weeraratne, S. D.; Amani, V. M.; Wang, Y.; et al. (2010). Neuralized1 causes apoptosis and downregulates Notch target genes in medulloblastoma. Neuro-oncology, 12, 1244-1256.
    • (2010) Neuro-oncology , vol.12 , pp. 1244-1256
    • Teider, N.1    Scott, D.K.2    Neiss, A.3    Weeraratne, S.D.4    Amani, V.M.5    Wang, Y.6
  • 150
    • 51649111238 scopus 로고    scopus 로고
    • Frequent promoter hypermethylation and transcriptional downregulation of the NDRG2 gene at 14q11.2 in primary glioblastoma
    • Tepel, M.; Roerig, P.; Wolter, M.; Gutmann, D. H.; Perry, A.; Reifenberger, G.; et al. (2008). Frequent promoter hypermethylation and transcriptional downregulation of the NDRG2 gene at 14q11.2 in primary glioblastoma. International Journal of Cancer, 123, 2080-2086.
    • (2008) International Journal of Cancer , vol.123 , pp. 2080-2086
    • Tepel, M.1    Roerig, P.2    Wolter, M.3    Gutmann, D.H.4    Perry, A.5    Reifenberger, G.6
  • 152
    • 59149096527 scopus 로고    scopus 로고
    • Prognostic significance of global histone modifications in resected squamous cell carcinoma of the esophagus
    • 18953329
    • Tzao, C.; Tung, H. J.; Jin, J. S.; Sun, G. H.; Hsu, H. S.; Chen, B. H.; et al. (2009). Prognostic significance of global histone modifications in resected squamous cell carcinoma of the esophagus. Modern Pathology, 22, 252-260.
    • (2009) Modern Pathology , vol.22 , pp. 252-260
    • Tzao, C.1    Tung, H.J.2    Jin, J.S.3    Sun, G.H.4    Hsu, H.S.5    Chen, B.H.6
  • 153
    • 34250761428 scopus 로고    scopus 로고
    • Continuous intracranial administration of suberoylanilide hydroxamic acid (SAHA) inhibits tumor growth in an orthotopic glioma model
    • DOI 10.1007/s11060-007-9337-z
    • Ugur, H. C.; Ramakrishna, N.; Bello, L.; Menon, L. G.; Kim, S. K.; Black, P. M.; et al. (2007). Continuous intracranial administration of suberoylanilide hydroxamic acid (SAHA) inhibits tumor growth in an orthotopic glioma model. Journal of Neuro-oncology, 83, 267-275. (Pubitemid 46952237)
    • (2007) Journal of Neuro-Oncology , vol.83 , Issue.3 , pp. 267-275
    • Ugur, H.C.1    Ramakrishna, N.2    Bello, L.3    Menon, L.G.4    Kim, S.-K.5    Black, P.M.6    Carroll, R.S.7
  • 155
    • 7044245474 scopus 로고    scopus 로고
    • ICBP90, an E2F-1 target, recruits HDAC1 and binds to methyl-CpG through its SRA domain
    • DOI 10.1038/sj.onc.1208053
    • Unoki, M.; Nishidate, T.; & Nakamura, Y. (2004). ICBP90, an E2F-1 target, recruits HDAC1 and binds to methyl-CpG through its SRA domain. Oncogene, 23, 7601-7610. (Pubitemid 39424918)
    • (2004) Oncogene , vol.23 , Issue.46 , pp. 7601-7610
    • Unoki, M.1    Nishidate, T.2    Nakamura, Y.3
  • 157
  • 158
    • 67650472284 scopus 로고    scopus 로고
    • Aberrant methylation and reduced expression of LHX9 in malignant gliomas of childhood
    • 19568415
    • Vladimirova, V.; Mikeska, T.; Waha, A.; Soerensen, N.; Xu, J.; Reynolds, P. C.; et al. (2009). Aberrant methylation and reduced expression of LHX9 in malignant gliomas of childhood. Neoplasia, 11, 700-711.
    • (2009) Neoplasia , vol.11 , pp. 700-711
    • Vladimirova, V.1    Mikeska, T.2    Waha, A.3    Soerensen, N.4    Xu, J.5    Reynolds, P.C.6
  • 159
    • 79952262759 scopus 로고    scopus 로고
    • Histone deacetylase (HDAC) inhibitors in recent clinical trials for cancer therapy
    • 21258646
    • Wagner, J. M.; Hackanson, B.; Lubbert, M.; & Jung, M. (2010). Histone deacetylase (HDAC) inhibitors in recent clinical trials for cancer therapy. Clinical Epigenetics, 1, 117-136.
    • (2010) Clinical Epigenetics , vol.1 , pp. 117-136
    • Wagner, J.M.1    Hackanson, B.2    Lubbert, M.3    Jung, M.4
  • 161
    • 15744392240 scopus 로고    scopus 로고
    • Epigenetic silencing of the protocadherin family member PCDH-γ-A11 in astrocytomas
    • DOI 10.1593/neo.04490
    • Waha, A.; Guntner, S.; Huang, T. H.; Yan, P. S.; Arslan, B.; Pietsch, T.; et al. (2005). Epigenetic silencing of the protocadherin family member PCDH-gamma-A11 in astrocytomas. Neoplasia, 7, 193-199. (Pubitemid 40411631)
    • (2005) Neoplasia , vol.7 , Issue.3 , pp. 193-199
    • Waha, A.1    Guntner, S.2    Huang, T.H.-M.3    Yan, P.S.4    Arslan, B.5    Pietsch, T.6    Wiestler, O.D.7    Waha, A.8
  • 162
    • 0029787059 scopus 로고    scopus 로고
    • Diversity and specialization of mammalian SWI/SNF complexes
    • Wang, W.; Xue, Y.; Zhou, S.; Kuo, A.; Cairns, B. R.; & Crabtree, G. R. (1996). Diversity and specialization of mammalian SWI/SNF complexes. Genes & Development, 10, 2117-2130. (Pubitemid 26303868)
    • (1996) Genes and Development , vol.10 , Issue.17 , pp. 2117-2130
    • Wang, W.1    Xue, Y.2    Zhou, S.3    Kuo, A.4    Cairns, B.R.5    Crabtree, G.R.6
  • 163
    • 34548544648 scopus 로고    scopus 로고
    • Chromatin remodeling and cancer, part II: ATP-dependent chromatin remodeling
    • DOI 10.1016/j.molmed.2007.07.004, PII S1471491407001475
    • Wang, G. G.; Allis, C. D.; & Chi, P. (2007). Chromatin remodeling and cancer, part II: ATP-dependent chromatin remodeling. Trends in Molecular Medicine, 13, 373-380. (Pubitemid 47385382)
    • (2007) Trends in Molecular Medicine , vol.13 , Issue.9 , pp. 373-380
    • Wang, G.G.1    Allis, C.D.2    Chi, P.3
  • 164
    • 56649103900 scopus 로고    scopus 로고
    • Deregulation of histone lysine methyltransferases contributes to oncogenic transformation of human bronchoepithelial cells
    • 18980680
    • Watanabe, H.; Soejima, K.; Yasuda, H.; Kawada, I.; Nakachi, I.; Yoda, S.; et al. (2008). Deregulation of histone lysine methyltransferases contributes to oncogenic transformation of human bronchoepithelial cells. Cancer Cell International, 8, 15.
    • (2008) Cancer Cell International , vol.8 , pp. 15
    • Watanabe, H.1    Soejima, K.2    Yasuda, H.3    Kawada, I.4    Nakachi, I.5    Yoda, S.6
  • 165
    • 52649127455 scopus 로고    scopus 로고
    • HKI 46F08, a novel potent histone deacetylase inhibitor, exhibits antitumoral activity against embryonic childhood cancer cells
    • 18765999
    • Wegener, D.; Deubzer, H. E.; Oehme, I.; Milde, T.; Hildmann, C.; Schwienhorst, A.; et al. (2008). HKI 46F08, a novel potent histone deacetylase inhibitor, exhibits antitumoral activity against embryonic childhood cancer cells. Anti-Cancer Drugs, 19, 849-857.
    • (2008) Anti-Cancer Drugs , vol.19 , pp. 849-857
    • Wegener, D.1    Deubzer, H.E.2    Oehme, I.3    Milde, T.4    Hildmann, C.5    Schwienhorst, A.6
  • 166
    • 84865283964 scopus 로고    scopus 로고
    • Early prediction of response to Vorinostat in an orthotopic rat glioma model
    • 22302519
    • Wei, L.; Hong, S.; Yoon, Y.; Hwang, S. N.; Park, J. C.; Zhang, Z.; et al. (2012). Early prediction of response to Vorinostat in an orthotopic rat glioma model. NMR in Biomedicine, 25, 1104-1111.
    • (2012) NMR in Biomedicine , vol.25 , pp. 1104-1111
    • Wei, L.1    Hong, S.2    Yoon, Y.3    Hwang, S.N.4    Park, J.C.5    Zhang, Z.6
  • 167
    • 80054705372 scopus 로고    scopus 로고
    • Prolonged survival with valproic acid use in the EORTC/NCIC temozolomide trial for glioblastoma
    • 21880994
    • Weller, M.; Gorlia, T.; Cairncross, J. G.; van den Bent, M. J.; Mason, W.; Belanger, K.; et al. (2011). Prolonged survival with valproic acid use in the EORTC/NCIC temozolomide trial for glioblastoma. Neurology, 77, 1156-1164.
    • (2011) Neurology , vol.77 , pp. 1156-1164
    • Weller, M.1    Gorlia, T.2    Cairncross, J.G.3    Van Den Bent, M.J.4    Mason, W.5    Belanger, K.6
  • 168
    • 77956385727 scopus 로고    scopus 로고
    • Identification and characterization of two novel primate-specific histone H3 variants, H3.X and H3.Y
    • 20819935
    • Wiedemann, S. M.; Mildner, S. N.; Bönisch, C.; Israel, L.; Maiser, A.; Matheisl, S.; et al. (2010). Identification and characterization of two novel primate-specific histone H3 variants, H3.X and H3.Y. The Journal of Cell Biology, 190, 777-791.
    • (2010) The Journal of Cell Biology , vol.190 , pp. 777-791
    • Wiedemann, S.M.1    Mildner, S.N.2    Bönisch, C.3    Israel, L.4    Maiser, A.5    Matheisl, S.6
  • 169
    • 56249124221 scopus 로고    scopus 로고
    • Valproic acid was well tolerated in heavily pretreated pediatric patients with high-grade glioma
    • 18679579
    • Wolff, J. E.; Kramm, C.; Kortmann, R. D.; Pietsch, T.; Rutkowski, S.; Jorch, N.; et al. (2008). Valproic acid was well tolerated in heavily pretreated pediatric patients with high-grade glioma. Journal of Neuro-oncology, 90, 309-314.
    • (2008) Journal of Neuro-oncology , vol.90 , pp. 309-314
    • Wolff, J.E.1    Kramm, C.2    Kortmann, R.D.3    Pietsch, T.4    Rutkowski, S.5    Jorch, N.6
  • 170
    • 84874697715 scopus 로고    scopus 로고
    • National Library of Medicine, U.S. National Institutes of Health (NIH), Food and Drug Administration (FDA)
    • National Library of Medicine, U.S. National Institutes of Health (NIH), Food and Drug Administration (FDA). (2012). Available at: http://clinicaltrials. gov/.
    • (2012)
  • 171
    • 54249127417 scopus 로고    scopus 로고
    • Abnormal DNA methylation of CD133 in colorectal and glioblastoma tumors
    • 18829568
    • Yi, J. M.; Tsai, H. C.; Glockner, S. C.; Lin, S.; Ohm, J. E.; Easwaran, H.; et al. (2008). Abnormal DNA methylation of CD133 in colorectal and glioblastoma tumors. Cancer Research, 68, 8094-8103.
    • (2008) Cancer Research , vol.68 , pp. 8094-8103
    • Yi, J.M.1    Tsai, H.C.2    Glockner, S.C.3    Lin, S.4    Ohm, J.E.5    Easwaran, H.6
  • 172
    • 33847372445 scopus 로고    scopus 로고
    • Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor: Effects on gene expression and growth of glioma cells in vitro and in vivo
    • DOI 10.1158/1078-0432.CCR-06-1261
    • Yin, D.; Ong, J. M.; Hu, J.; Desmond, J. C.; Kawamata, N.; Konda, B. M.; et al. (2007). Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor: effects on gene expression and growth of glioma cells in vitro and in vivo. Clinical Cancer Research, 13, 1045-1052. (Pubitemid 46340384)
    • (2007) Clinical Cancer Research , vol.13 , Issue.3 , pp. 1045-1052
    • Yin, D.1    Ong, J.M.2    Hu, J.3    Desmond, J.C.4    Kawamata, N.5    Konda, B.M.6    Black, K.L.7    Koeffler, H.P.8
  • 173
    • 52949083797 scopus 로고    scopus 로고
    • Mitochondrial Bax translocation partially mediates synergistic cytotoxicity between histone deacetylase inhibitors and proteasome inhibitors in glioma cells
    • 18445700
    • Yu, C.; Friday, B. B.; Yang, L.; Atadja, P.; Wigle, D.; Sarkaria, J.; et al. (2008). Mitochondrial Bax translocation partially mediates synergistic cytotoxicity between histone deacetylase inhibitors and proteasome inhibitors in glioma cells. Neuro-oncology, 10, 309-319.
    • (2008) Neuro-oncology , vol.10 , pp. 309-319
    • Yu, C.1    Friday, B.B.2    Yang, L.3    Atadja, P.4    Wigle, D.5    Sarkaria, J.6


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