메뉴 건너뛰기




Volumn 65, Issue 7, 2005, Pages 2565-2571

EMP3, a myelin-related gene located in the critical 19q13.3 region, is epigenetically silenced and exhibits features of a candidate tumor suppressor in glioma and neuroblastoma

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; EPITHELIAL MEMBRANE PROTEIN 3; MYELIN ASSOCIATED GLYCOPROTEIN; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

EID: 20144387913     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-04-4283     Document Type: Article
Times cited : (137)

References (40)
  • 2
    • 0041475779 scopus 로고    scopus 로고
    • Neuroblastoma: Biology and molecular and chromosomal pathology
    • Schwab M, Westermann F, Hero B, Berthold F. Neuroblastoma: biology and molecular and chromosomal pathology. Lancet Oncol 2003;4:472-80.
    • (2003) Lancet Oncol , vol.4 , pp. 472-480
    • Schwab, M.1    Westermann, F.2    Hero, B.3    Berthold, F.4
  • 3
    • 0032494479 scopus 로고    scopus 로고
    • Specific genetic predictors of chemotherapeutic response and survival in patients with anaplastic oligodendrogliomas
    • Cairncross JG, Ueki K, Zlatescu MC, et al. Specific genetic predictors of chemotherapeutic response and survival in patients with anaplastic oligodendrogliomas. J Natl Cancer Inst 1998;90:1473-9.
    • (1998) J Natl Cancer Inst , vol.90 , pp. 1473-1479
    • Cairncross, J.G.1    Ueki, K.2    Zlatescu, M.C.3
  • 6
    • 0025979843 scopus 로고
    • Clinical relevance of tumor cell ploidy and N-myc gene amplification in childhood neuroblastoma: A Pediatric Oncology Group study
    • Look AT, Hayes FA, Shuster JJ, et al. Clinical relevance of tumor cell ploidy and N-myc gene amplification in childhood neuroblastoma: a Pediatric Oncology Group study. J Clin Oncol 1991;9:581-91.
    • (1991) J Clin Oncol , vol.9 , pp. 581-591
    • Look, A.T.1    Hayes, F.A.2    Shuster, J.J.3
  • 7
    • 4344688973 scopus 로고    scopus 로고
    • Clustering of gene hypermethylation associated with clinical risk groups in neuroblastoma
    • Alaminos M, Davalos V, Cheung NK, Gerald WL, Esteller M. Clustering of gene hypermethylation associated with clinical risk groups in neuroblastoma. J Natl Cancer Inst 2004;96:1208-19.
    • (2004) J Natl Cancer Inst , vol.96 , pp. 1208-1219
    • Alaminos, M.1    Davalos, V.2    Cheung, N.K.3    Gerald, W.L.4    Esteller, M.5
  • 8
    • 0027239723 scopus 로고
    • Revisions of the international criteria for neuroblastoma diagnosis, staging, and response to treatment
    • Brodeur GM, Pritchard J, Berthold F, et al. Revisions of the international criteria for neuroblastoma diagnosis, staging, and response to treatment. J Clin Oncol 1993;11:1466-77.
    • (1993) J Clin Oncol , vol.11 , pp. 1466-1477
    • Brodeur, G.M.1    Pritchard, J.2    Berthold, F.3
  • 9
    • 0034907626 scopus 로고    scopus 로고
    • Loss of heterozygosity at 19q13.3 is associated with locally aggressive neuroblastoma
    • Mora J, Cheung NK, Chen L, Qin J, Gerald W. Loss of heterozygosity at 19q13.3 is associated with locally aggressive neuroblastoma. Clin Cancer Res 2001;7:1358-61.
    • (2001) Clin Cancer Res , vol.7 , pp. 1358-1361
    • Mora, J.1    Cheung, N.K.2    Chen, L.3    Qin, J.4    Gerald, W.5
  • 10
    • 0003043605 scopus 로고
    • Neoplasms of the central nervous system
    • DeVita VT Jr, Hellman S, Rosenberg SA, editors. Philadelphia: Lippincott
    • Levin VA, Gutin PH, Leibel S. Neoplasms of the central nervous system. In: DeVita VT Jr, Hellman S, Rosenberg SA, editors. Cancer principles and practice of oncology. Philadelphia: Lippincott; 1993. p. 1679-737.
    • (1993) Cancer Principles and Practice of Oncology , pp. 1679-1737
    • Levin, V.A.1    Gutin, P.H.2    Leibel, S.3
  • 11
    • 0029059911 scopus 로고
    • Allelic loss at 1p and 19q frequently occurs in association and may represent early oncogenic events in oligodendroglial tumors
    • Bello MJ, Leone PE, Vaquero J, et al. Allelic loss at 1p and 19q frequently occurs in association and may represent early oncogenic events in oligodendroglial tumors. Int J Cancer 1995;64:207-10.
    • (1995) Int J Cancer , vol.64 , pp. 207-210
    • Bello, M.J.1    Leone, P.E.2    Vaquero, J.3
  • 12
    • 12144290789 scopus 로고    scopus 로고
    • Prognostic value of 1p, 19q, 9p, 10q, and EGFR-FISH analyses in recurrent oligodendrogliomas
    • Fallon KB, Palmer CA, Roth KA, et al. Prognostic value of 1p, 19q, 9p, 10q, and EGFR-FISH analyses in recurrent oligodendrogliomas. J Neuropathol Exp Neurol 2004;63:314-22.
    • (2004) J Neuropathol Exp Neurol , vol.63 , pp. 314-322
    • Fallon, K.B.1    Palmer, C.A.2    Roth, K.A.3
  • 13
    • 0030883778 scopus 로고    scopus 로고
    • Molecular genetic evidence for subtypes of oligoastrocytomas
    • Maintz D, Fiedler K, Koopmann J, et al. Molecular genetic evidence for subtypes of oligoastrocytomas. J Neuropathol Exp Neurol 1997;56:1098-104.
    • (1997) J Neuropathol Exp Neurol , vol.56 , pp. 1098-1104
    • Maintz, D.1    Fiedler, K.2    Koopmann, J.3
  • 14
    • 0028882666 scopus 로고
    • Genetic alterations associated with the evolution and progression of astrocytic brain tumours
    • Ohgaki H, Schauble B, zur Hausen A, von Ammon K, Kleihues P. Genetic alterations associated with the evolution and progression of astrocytic brain tumours. Virchows Arch 1995;427:113-8.
    • (1995) Virchows Arch , vol.427 , pp. 113-118
    • Ohgaki, H.1    Schauble, B.2    Zur Hausen, A.3    Von Ammon, K.4    Kleihues, P.5
  • 15
    • 0033566061 scopus 로고    scopus 로고
    • Localization of common deletion regions on 1p and 19q in human gliomas and their association with histological subtype
    • Smith JS, Alderete B, Minn Y, et al. Localization of common deletion regions on 1p and 19q in human gliomas and their association with histological subtype. Oncogene 1999;18:4144-52.
    • (1999) Oncogene , vol.18 , pp. 4144-4152
    • Smith, J.S.1    Alderete, B.2    Minn, Y.3
  • 16
    • 0033866013 scopus 로고    scopus 로고
    • Mapping of the chromosome 19 q-arm glioma tumor suppressor gene using fluorescence in situ hybridization and novel microsatellite markers
    • Smith JS, Tachibana I, Lee HK, et al. Mapping of the chromosome 19 q-arm glioma tumor suppressor gene using fluorescence in situ hybridization and novel microsatellite markers. Genes Chromosomes Cancer 2000;29:16-25.
    • (2000) Genes Chromosomes Cancer , vol.29 , pp. 16-25
    • Smith, J.S.1    Tachibana, I.2    Lee, H.K.3
  • 18
    • 0033985151 scopus 로고    scopus 로고
    • Hypermethylation-associated inactivation of p14(ARF) is independent of p16(INK4a) methylation and p53 mutational status
    • Esteller M, Tortola S, Toyota M, et al. Hypermethylation-associated inactivation of p14(ARF) is independent of p16(INK4a) methylation and p53 mutational status. Cancer Res 2000;60:129-33.
    • (2000) Cancer Res , vol.60 , pp. 129-133
    • Esteller, M.1    Tortola, S.2    Toyota, M.3
  • 19
    • 0030579151 scopus 로고    scopus 로고
    • Epithelial membrane protein-2 and epithelial membrane protein-3: Two novel members of the peripheral myelin protein 22 gene family
    • Taylor V, Suter U. Epithelial membrane protein-2 and epithelial membrane protein-3: two novel members of the peripheral myelin protein 22 gene family. Gene 1996;175:115-20.
    • (1996) Gene , vol.175 , pp. 115-120
    • Taylor, V.1    Suter, U.2
  • 20
    • 0030461764 scopus 로고    scopus 로고
    • Characterization of a tumor-associated gene, a member of a novel family of genes encoding membrane glycoproteins
    • Ben-Porath I, Benvenisty N. Characterization of a tumor-associated gene, a member of a novel family of genes encoding membrane glycoproteins. Gene 1996;183:69-75.
    • (1996) Gene , vol.183 , pp. 69-75
    • Ben-Porath, I.1    Benvenisty, N.2
  • 21
    • 0345518007 scopus 로고    scopus 로고
    • Regional localization of the human epithelial membrane protein genes 1, 2, and 3 (EMP1, EMP2, EMP3) to 12p12.3, 16p13.2, and 19q13.3
    • Liehr T, Kuhlenbaumer G, Wulf P, et al. Regional localization of the human epithelial membrane protein genes 1, 2, and 3 (EMP1, EMP2, EMP3) to 12p12.3, 16p13.2, and 19q13.3. Genomics 1999;58:106-8.
    • (1999) Genomics , vol.58 , pp. 106-108
    • Liehr, T.1    Kuhlenbaumer, G.2    Wulf, P.3
  • 22
    • 0034139858 scopus 로고    scopus 로고
    • Clinical categories of neuroblastoma are associated with different patterns of loss of heterozygosity on chromosome arm 1p
    • Mora J, Cheung NK, Kushner BH, et al. Clinical categories of neuroblastoma are associated with different patterns of loss of heterozygosity on chromosome arm 1p. J Mol Diagn 2000;2:37-46.
    • (2000) J Mol Diagn , vol.2 , pp. 37-46
    • Mora, J.1    Cheung, N.K.2    Kushner, B.H.3
  • 23
    • 0038444702 scopus 로고    scopus 로고
    • Evolving significance of prognostic markers associated with new treatment strategies in neuroblastoma
    • Mora J, Gerald WL, Cheung NK. Evolving significance of prognostic markers associated with new treatment strategies in neuroblastoma. Cancer Lett 2003;197:119-24.
    • (2003) Cancer Lett , vol.197 , pp. 119-124
    • Mora, J.1    Gerald, W.L.2    Cheung, N.K.3
  • 24
    • 0043092201 scopus 로고    scopus 로고
    • Genome-wide analysis of gene expression associated with MYCN in human neuroblastoma
    • Alaminos M, Mora J, Cheung NK, et al. Genome-wide analysis of gene expression associated with MYCN in human neuroblastoma. Cancer Res 2003;63:4538-46.
    • (2003) Cancer Res , vol.63 , pp. 4538-4546
    • Alaminos, M.1    Mora, J.2    Cheung, N.K.3
  • 25
    • 0022388606 scopus 로고
    • Association of multiple copies of the N-myc oncogene with rapid progression of neuroblastomas
    • Seeger RC, Brodeur GM, Sather H, et al. Association of multiple copies of the N-myc oncogene with rapid progression of neuroblastomas. N Engl J Med 1985;313:1111-6.
    • (1985) N Engl J Med , vol.313 , pp. 1111-1116
    • Seeger, R.C.1    Brodeur, G.M.2    Sather, H.3
  • 26
    • 0842309106 scopus 로고    scopus 로고
    • MYCN in neuronal tumours
    • Schwab M. MYCN in neuronal tumours. Cancer Lett 2004;204:179-87.
    • (2004) Cancer Lett , vol.204 , pp. 179-187
    • Schwab, M.1
  • 27
    • 0037099620 scopus 로고    scopus 로고
    • Transcript map of the 3.7-Mb D19S112-D19S246 candidate tumor suppressor region on the long arm of chromosome 19
    • Hartmann C, Johnk L, Kitange G, et al. Transcript map of the 3.7-Mb D19S112-D19S246 candidate tumor suppressor region on the long arm of chromosome 19. Cancer Res 2002;62:4100-8.
    • (2002) Cancer Res , vol.62 , pp. 4100-4108
    • Hartmann, C.1    Johnk, L.2    Kitange, G.3
  • 28
    • 0027980906 scopus 로고
    • The putative glioma tumor suppressor gene on chromosome 19q maps between APOC2 and HRC
    • Rubio MP, Correa KM, Ueki K, et al. The putative glioma tumor suppressor gene on chromosome 19q maps between APOC2 and HRC. Cancer Res 1994;54:4760-3.
    • (1994) Cancer Res , vol.54 , pp. 4760-4763
    • Rubio, M.P.1    Correa, K.M.2    Ueki, K.3
  • 29
    • 0030444184 scopus 로고    scopus 로고
    • Refined deletion mapping of the chromosome 19q glioma tumor suppressor gene to the D19S412-STD interval
    • Rosenberg JE, Lisle DK, Burwick JA, et al. Refined deletion mapping of the chromosome 19q glioma tumor suppressor gene to the D19S412-STD interval. Oncogene 1996;13:2483-5.
    • (1996) Oncogene , vol.13 , pp. 2483-2485
    • Rosenberg, J.E.1    Lisle, D.K.2    Burwick, J.A.3
  • 30
    • 0033631414 scopus 로고    scopus 로고
    • The peripheral myelin protein 22 and epithelial membrane protein family
    • Jetten AM, Suter U. The peripheral myelin protein 22 and epithelial membrane protein family. Prog Nucleic Acid Res Mol Biol 2000;64:97-129.
    • (2000) Prog Nucleic Acid Res Mol Biol , vol.64 , pp. 97-129
    • Jetten, A.M.1    Suter, U.2
  • 31
    • 0032960181 scopus 로고    scopus 로고
    • Cancer epigenetics comes of age
    • Jones PA, Laird PW. Cancer epigenetics comes of age. Nat Genet 1999;21:163-7.
    • (1999) Nat Genet , vol.21 , pp. 163-167
    • Jones, P.A.1    Laird, P.W.2
  • 32
    • 0037068312 scopus 로고    scopus 로고
    • CpG island hypermethylation and tumor suppressor genes: A booming present, a brighter future
    • Esteller M. CpG island hypermethylation and tumor suppressor genes: a booming present, a brighter future. Oncogene 2002;21:5427-40.
    • (2002) Oncogene , vol.21 , pp. 5427-5440
    • Esteller, M.1
  • 33
    • 0345357773 scopus 로고    scopus 로고
    • Gene silencing in cancer in association with promoter hypermethylation
    • Herman JG, Baylin SB. Gene silencing in cancer in association with promoter hypermethylation. N Engl J Med 2003;349:2042-54.
    • (2003) N Engl J Med , vol.349 , pp. 2042-2054
    • Herman, J.G.1    Baylin, S.B.2
  • 34
    • 0343621494 scopus 로고    scopus 로고
    • Aberrant CpG-island methylation has non-random and tumour-type-specific patterns
    • Costello JF, Fruhwald MC, Smiraglia DJ, et al. Aberrant CpG-island methylation has non-random and tumour-type-specific patterns. Nat Genet 2000;24:132-8.
    • (2000) Nat Genet , vol.24 , pp. 132-138
    • Costello, J.F.1    Fruhwald, M.C.2    Smiraglia, D.J.3
  • 36
    • 0034626988 scopus 로고    scopus 로고
    • Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents
    • Esteller M, Garcia-Foncillas J, Andion E, et al. Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents. N Engl J Med 2000;343:1350-4.
    • (2000) N Engl J Med , vol.343 , pp. 1350-1354
    • Esteller, M.1    Garcia-Foncillas, J.2    Andion, E.3
  • 37
    • 0029011539 scopus 로고
    • 5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers
    • Merlo A, Herman JG, Mao L, et al. 5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers. Nat Med 1995;1:686-92.
    • (1995) Nat Med , vol.1 , pp. 686-692
    • Merlo, A.1    Herman, J.G.2    Mao, L.3
  • 38
    • 0029967152 scopus 로고    scopus 로고
    • Silencing of p16/CDKN2 expression in human gliomas by methylation and chromatin condensation
    • Costello JF, Berger MS, Huang HS, Cavenee WK. Silencing of p16/CDKN2 expression in human gliomas by methylation and chromatin condensation. Cancer Res 1996;56:2405-10.
    • (1996) Cancer Res , vol.56 , pp. 2405-2410
    • Costello, J.F.1    Berger, M.S.2    Huang, H.S.3    Cavenee, W.K.4
  • 39
    • 0036532064 scopus 로고    scopus 로고
    • Tumor-specific down-regulation of the tumor necrosis factor-related apoptosis-inducing ligand decoy receptors DCR1 and DCR2 is associated with dense promoter hypermethylation
    • van Noesel MM, van Bezouw S, Salomons GS, et al. Tumor-specific down-regulation of the tumor necrosis factor-related apoptosis-inducing ligand decoy receptors DCR1 and DCR2 is associated with dense promoter hypermethylation. Cancer Res 2002;62:2157-61.
    • (2002) Cancer Res , vol.62 , pp. 2157-2161
    • Van Noesel, M.M.1    Van Bezouw, S.2    Salomons, G.S.3
  • 40
    • 0344844484 scopus 로고    scopus 로고
    • The contribution of genetic and epigenetic mechanisms to gene silencing in oligodendrogliomas
    • Hong C, Bollen AW, Costello JF. The contribution of genetic and epigenetic mechanisms to gene silencing in oligodendrogliomas. Cancer Res 2003;63:7600-5.
    • (2003) Cancer Res , vol.63 , pp. 7600-7605
    • Hong, C.1    Bollen, A.W.2    Costello, J.F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.