The SHREW1 gene, frequently deleted in oligodendrogliomas, functions to inhibit cell adhesion and migration

Cancer Biology and Therapy

Volumn 5, Issue 3, 2006, Pages 300-304

  McDonald, J Matthew ^a   Dunlap, Sarah ^a   Cogdell, David ^a   Dunmire, Valerie ^a   Wei, Qingyi ^a   Starzinski Powitz, Anna ^b   Sawaya, Raymond ^a   Bruner, Janet ^a   Fuller, Gregory N ^a   Aldape, Kenneth ^a   Zhang, Wei ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b UNIVERSITY HOSPITAL FRANKFURT   (Germany)

Author keywords

1p36; Allelic loss; Cell adhesion; Oligodendroglioma; QuMA; SHREW1

Indexed keywords

MEMBRANE PROTEIN; PROTEIN SHREW1; UNCLASSIFIED DRUG;

ARTICLE; CARCINOGENESIS; CELL ADHESION; CELL MIGRATION; GENE DELETION; GENE EXPRESSION; OLIGODENDROGLIOMA;

EID: 33646419301     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.5.3.2391     Document Type: Article

References (22)

1. Bello MJ, Vaquero J, de Campos JM, Kusak ME, Sarasa JL, Saez-Castresana J, et al. Molecular analysis of chromosome 1 abnormalities in human gliomas reveals frequent loss of 1p in oligodendroglial tumors. Int J Cancer 1994; 57:172-5.
2. Reifenberger J, Reifenberger G, Liu L, James CD, Wechsler W, Collins VP. Molecular genetic analysis of oligodendroglial tumors shows preferential allelic deletions on 19q and 1p. Am J Pathol 1994; 145:1175-90.
3. Cairncross JG, Ueki K, Zlatescu MC, Lisle DK, Finkelstein DM, Hammond RR, et al. Specific genetic predictors of chemotherapeutic response and survival in patients with anaplastic oligodendrogliomas. J Natl Cancer Inst 1998; 90:1473-9.
4. Zlatescu MC, TehraniYazdi A, Sasaki H, Megyesi JF, Betensky RA, Louis DN, et al. Tumor location and growth pattern correlate with genetic signature in oligodendroglial neoplasms. Cancer Res 2001; 61:6713-5.
5. Megyesi JF, Kachur E, Lee DH, Zlatescu MC, Betensky RA, Forsyth PA, et al. Imaging correlates of molecular signatures in oligodendrogliomas. Clin Cancer Res 2004; 10:4303-6.
6. Bello MJ, Leone PE, Vaquero J, de Campos JM, Kusak ME, Sarasa JL, et al. Allelic loss at 1p and 19q frequently occurs in association and may represent early oncogenic events in oligodendroglial tumors. Int J Cancer 1995; 64:207-10.
7. Smith JS, Alderete B, Minn Y, Borell TJ, Perry A, Mohapatra G, et al. Localization of common deletion regions on 1p and 19q in human gliomas and their association with histological subtype. Oncogene 1999; 18:4144-52.
8. Husemann K, Wolter M, Buschges R, Bostrom J, Sabel M, Reifenberger G. Identification of two distinct deleted regions on the short arm of chromosome 1 and rare mutation of the CDKN2C gene from 1p32 in oligodendroglial tumors. J Neuropathol Exp Neurol 1999; 58:1041-50.
9. Nigro JM, Takakashi MA, Ginzinger DG, Law M, Passe S, Jenkins RB, et al. Detection of 1p and 19q loss in oligodendroglioma by quantitative microsatellite analysis, a real-time quantitative polymerase chain reaction assay. Am J Pathol 2001; 158:1253-62.
10. Iuchi T, Namba H, Iwadate Y, Shishikura T, Kageyama H, Nakamura Y, et al. Identification of the small interstitial deletion at chromosome band 1p34-p35 and its association with poor outcome in oligodendroglial tumors. Genes Chromosomes Cancer 2002; 35:170-5.
11. Kraus JA, Koopmann J, Kaskel P, Maintz D, Brandner S, Schramm J, et al. Shared allelic losses on chromosomes 1p and 19q suggest a common origin of oligodendroglioma and oligoastrocytoma. J Neuropathol Exp Neurol 1995; 54:91-5.
12. Suzuki S, Moore IInd DH, Ginzinger DG, Godfrey TE, Barclay J, Powell B, et al. An approach to analysis of large-scale correlations between genome changes and clinical endpoints in ovarian cancer. Cancer Res 2000; 60:5382-5.
13. Ginzinger DG, Godfrey TE, Nigro J, Moore IInd DH, Suzuki S, Pallavicini MG, et al. Measurement of DNA copy number at microsatellite loci using quantitative PCR analysis. Cancer Res 2000; 60:5405-9.
14. Wheeler DL, Church DM, Edgar R, Federhen S, Helmberg W, Madden TL, et al. Database resources of the National Center for Biotechnology Information: Update. Nucleic Acids Res 2004; 32, (Database issue:D35-40).
15. Dong Z, Pang JS, Ng MH, Poon WS, Zhou L, Ng HK. Identification of two contiguous minimally deleted regions on chromosome 1p36.31-p36.32 in oligodendroglial tumours. Br J Cancer 2004; 91:1105-11.
16. Bharti S, Handrow-Metzmacher H, Zickenheiner S, Zeitvogel A, Baumann R, Starzinski-Powitz A. Novel membrane protein shrew-1 targets to cadherin-mediated junctions in polarized epithelial cells. Mol Biol Cell 2004; 15:397-406.
17. Shimoyama Y, Hirohashi S. Cadherin intercellular adhesion molecule in hepatocellular carcinomas: Loss of E-cadherin expression in an undifferentiated carcinoma. Cancer Lett 1991; 57:131-5.
18. Takeichi M. Cadherin cell adhesion receptors as a morphogenetic regulator. Science 1991; 251:1451-5.
19. Baker SJ, Preisinger AC, Jessup JM, Paraskeva C, Markowitz S, Willson JK, et al. p53 gene mutations occur in combination with 17p allelic deletions as late events in colorectal tumorigenesis. Cancer Res 1990; 50:7717-22.
20. Giancotti FG. Integrin signaling: Specificity and control of cell survival and cell cycle progression. Curr Opin Cell Biol 1997; 9:691-700.
21. Song SW, Fuller GN, Khan A, Kong S, Shen W, Taylor E, et al. IIp45, an insulin-like growth factor binding protein 2 (IGFBP-2) binding protein, antagonizes IGFBP-2 stimulation of glioma cell invasion. Proc Natl Acad Sci USA 2003; 100:13970-5.
22. Song SW, Fuller GN, Zheng H, Zhang W. Inactivation of the invasion inhibitory gene IIp45 by alternative splicing in gliomas. Cancer Res 2005; 65:3562-7.