Somatic Mutations, Allele Loss, and DNA Methylation of the Cub and Sushi Multiple Domains 1 (CSMD1) Gene Reveals Association with Early Age of Diagnosis in Colorectal Cancer Patients

PLoS ONE

Volumn 8, Issue 3, 2013, Pages

  Shull, Austin Y ^a   Clendenning, Megan L ^a   Ghoshal Gupta, Sampa ^a   Farrell, Christopher L ^b   Vangapandu, Hima V ^c   Dudas, Larry ^d   Wilkerson, Brent J ^e   Buckhaults, Phillip J ^a  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

^b PRESBYTERIAN COLLEGE   (United States)

^c UNIVERSITY OF TEXAS   (United States)

^d Northeast Georgia Medical Center   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 2A; NEUROGENIN 1; TRANSCRIPTION FACTOR RUNX3;

ADULT; AGED; ALLELIC IMBALANCE; ALX4 GENE; AMINO ACID SUBSTITUTION; ARTICLE; CDKN2A GENE; COLON CARCINOGENESIS; COLORECTAL CANCER; CPG ISLAND; CUB AND SUSHI MULTIPLE DOMAIN 1 GENE; DNA METHYLATION; EARLY CANCER; FEMALE; GENE; GENE FUNCTION; GENE IDENTIFICATION; GENE LOCUS; GENETIC ASSOCIATION; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; LOSS OF FUNCTION MUTATION; MAJOR CLINICAL STUDY; MALE; MUTATION RATE; MUTATIONAL ANALYSIS; NEUROG1 GENE; NUCLEOTIDE SEQUENCE; ONCOGENE K RAS; POLYMERASE CHAIN REACTION; RUNX3 GENE; SOMATIC MUTATION; TUMOR SUPPRESSOR GENE;

ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; ALLELES; ALLELIC IMBALANCE; CELL LINE, TUMOR; COLORECTAL NEOPLASMS; DNA METHYLATION; FEMALE; HUMANS; LOSS OF HETEROZYGOSITY; MALE; MEMBRANE PROTEINS; MICROSATELLITE INSTABILITY; MIDDLE AGED; MUTATION; MUTATION RATE; NEOPLASM STAGING; YOUNG ADULT;

EID: 84874688916     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0058731     Document Type: Article

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