Tim-3/galectin-9 signaling pathway mediates T-cell dysfunction and predicts poor prognosis in patients with hepatitis B virus-associated hepatocellular carcinoma

Hepatology

Volumn 56, Issue 4, 2012, Pages 1342-1351

  Li, Hang ^a   Wu, Ke ^a   Tao, Kaixiong ^a   Chen, Libo ^a   Zheng, Qichang ^a   Lu, Xiaoming ^a   Liu, Jun ^a   Shi, Liang ^a   Liu, Chuanqiao ^b   Wang, Guobin ^a   Zou, Weiping ^c  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b Wuhan Blood Center   (China)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ECALECTIN; GAMMA INTERFERON; MEMBRANE PROTEIN; T CELL IMMUNOGLOBULIN AND MUCIN DOMAIN CONTAINING MOLECULE 3; UNCLASSIFIED DRUG;

ADULT; AGED; ANTIGEN PRESENTING CELL; ARTICLE; CANCER PROGNOSIS; CANCER SURVIVAL; CD4 LYMPHOCYTE COUNT; CD8+ T LYMPHOCYTE; CELL AGING; CELL EXPANSION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; EFFECTOR CELL; FEMALE; FLOW CYTOMETRY; GENETIC MARKER; HEPATITIS B VIRUS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; KUPFFER CELL; LIVER CELL CARCINOMA; MAJOR CLINICAL STUDY; MALE; MICROENVIRONMENT; MYELOID DENDRITIC CELL; NEGATIVE FEEDBACK; PLASMACYTOID DENDRITIC CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; T LYMPHOCYTE; TUMOR ASSOCIATED LEUKOCYTE;

ADULT; AGED; CARCINOMA, HEPATOCELLULAR; CD4-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; FEMALE; GALECTINS; GENE EXPRESSION REGULATION, NEOPLASTIC; HEPATITIS B; HEPATITIS B VIRUS; HUMANS; KAPLAN-MEIER ESTIMATE; KUPFFER CELLS; LIVER NEOPLASMS; MALE; MEMBRANE PROTEINS; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; REAL-TIME POLYMERASE CHAIN REACTION; SAMPLING STUDIES; SIGNAL TRANSDUCTION; STATISTICS, NONPARAMETRIC; SURVIVAL ANALYSIS;

EID: 84867144615     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.25777     Document Type: Article

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