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Volumn 119, Issue 13, 2012, Pages 3064-3072

Tim-3 is an inducible human natural killer cell receptor that enhances interferon gamma production in response to galectin-9

Author keywords

[No Author keywords available]

Indexed keywords

ECALECTIN; GAMMA INTERFERON; I KAPPA B ALPHA; INTERLEUKIN 12; INTERLEUKIN 18; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; MITOGEN ACTIVATED PROTEIN KINASE; NATURAL KILLER CELL RECEPTOR; TIM 3 PROTEIN; UNCLASSIFIED DRUG;

EID: 84859192882     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2011-06-360321     Document Type: Article
Times cited : (301)

References (50)
  • 1
    • 33750686595 scopus 로고    scopus 로고
    • Human natural killer cell development
    • DOI 10.1111/j.1600-065X.2006.00451.x
    • Freud AG, Caligiuri MA. Human natural killer cell development. Immunol Rev. 2006;214:56-72. (Pubitemid 44707902)
    • (2006) Immunological Reviews , vol.214 , Issue.1 , pp. 56-72
    • Freud, A.G.1    Caligiuri, M.A.2
  • 2
    • 0037105453 scopus 로고    scopus 로고
    • Natural killer cell receptors: New biology and insights into the graft-versus-leukemia effect
    • DOI 10.1182/blood-2002-02-0350
    • Farag SS, Fehniger TA, Ruggeri L, Velardi A, Caligiuri MA. Natural killer cell receptors: new biology and new insights into the graft versus leukemia effect. Blood. 2002;100(6):1935-1947. (Pubitemid 35001221)
    • (2002) Blood , vol.100 , Issue.6 , pp. 1935-1947
    • Farag, S.S.1    Fehniger, T.A.2    Ruggeri, L.3    Velardi, A.4    Caligiuri, M.A.5
  • 3
    • 0036779576 scopus 로고    scopus 로고
    • Functional significance of the perforin/granzyme cell death pathway
    • DOI 10.1038/nri911
    • Trapani JA, Smyth MJ. Functional significance of the perforin/granzyme cell death pathway. Nat Rev Immunol. 2002;2(10):735-747. (Pubitemid 37328714)
    • (2002) Nature Reviews Immunology , vol.2 , Issue.10 , pp. 735-747
    • Trapani, J.A.1    Smyth, M.J.2
  • 4
    • 0032447111 scopus 로고    scopus 로고
    • Natural killer (NK) cell-mediated cytotoxicity: Differential use of TRAIL and Fas ligand by immature and mature primary human NK cells
    • DOI 10.1084/jem.188.12.2375
    • Zamai L, Ahmad M, Bennett IM, Azzoni L, Alnemri ES, Perussia B. Natural killer (NK) cell-mediated cytotoxicity: differential use of TRAIL and Fas ligand by immature and mature primary human NK cells. J Exp Med. 1998;188(12):2375- 2380. (Pubitemid 29028510)
    • (1998) Journal of Experimental Medicine , vol.188 , Issue.12 , pp. 2375-2380
    • Zamai, L.1    Ahmad, M.2    Bennett, I.M.3    Azzoni, L.4    Alnemri, E.S.5    Perussia, B.6
  • 5
    • 0031898453 scopus 로고    scopus 로고
    • Fc receptors on natural killer cells
    • Perussia B. Fc receptors on natural killer cells. Curr. Top. Microbiol Immunol. 1998;230:63-88.
    • (1998) Curr. Top. Microbiol Immunol. , vol.230 , pp. 63-88
    • Perussia, B.1
  • 6
    • 0024792513 scopus 로고
    • Biology of natural killer cells
    • Trinchieri G. Biology of natural killer cells. Adv Immunol. 1989;47:187-376. (Pubitemid 20010960)
    • (1989) Advances in Immunology , vol.47 , pp. 187-376
    • Trinchieri, G.1
  • 7
    • 0034780206 scopus 로고    scopus 로고
    • The biology of natural killer cells in cancer, infection, and pregnancy
    • DOI 10.1016/S0301-472X(01)00696-8, PII S0301472X01006968
    • Miller JS. The biology of natural killer cells in cancer, infection and pregnancy. Exp Hematol. 2001;29(10):1157-1168. (Pubitemid 32936575)
    • (2001) Experimental Hematology , vol.29 , Issue.10 , pp. 1157-1168
    • Miller, J.S.1
  • 8
    • 20144388509 scopus 로고    scopus 로고
    • Successful adoptive transfer and in vivo expansion of human haploidentical NK cells in patients with cancer
    • Miller JS, Soignier Y, Panoskaltsis-Mortari A, et al. Successful adoptive transfer and in vivo expansion of human haploidentical NK cells in patients with cancer. Blood. 2005;105(8):3051-3057.
    • (2005) Blood , vol.105 , Issue.8 , pp. 3051-3057
    • Miller, J.S.1    Soignier, Y.2    Panoskaltsis-Mortari, A.3
  • 9
    • 11144299492 scopus 로고    scopus 로고
    • NK cell recognition
    • DOI 10.1146/annurev.immunol.23.021704.115526
    • Lanier LL. NK cell recognition. Ann Rev Immunol. 2005;23:225-274. (Pubitemid 40563170)
    • (2005) Annual Review of Immunology , vol.23 , pp. 225-274
    • Lanier, L.L.1
  • 10
    • 52049083404 scopus 로고    scopus 로고
    • The regulation of NK cell function and development
    • Chung JW, Yoon SR, Choi I. The regulation of NK cell function and development. Front Biosci. 2008;13:6432-6442.
    • (2008) Front Biosci. , vol.13 , pp. 6432-6442
    • Chung, J.W.1    Yoon, S.R.2    Choi, I.3
  • 11
    • 77950408682 scopus 로고    scopus 로고
    • Regulation of human NK-cell cytokine and chemokine production by target cell recognition
    • Fauriat C, Long EO, Ljunggren HG, Bryceson YT. Regulation of human NK-cell cytokine and chemokine production by target cell recognition. Blood. 2010;115(11):2167-2176.
    • (2010) Blood , vol.115 , Issue.11 , pp. 2167-2176
    • Fauriat, C.1    Long, E.O.2    Ljunggren, H.G.3    Bryceson, Y.T.4
  • 12
    • 77749304012 scopus 로고    scopus 로고
    • T-bet, a Th1 transcription factor regulates the expression of Tim-3
    • Anderson AC, Lord GM, Dardalhon V, et al. T-bet, a Th1 transcription factor regulates the expression of Tim-3. Eur J Immunol. 2010;40(3):859-866.
    • (2010) Eur J Immunol. , vol.40 , Issue.3 , pp. 859-866
    • Anderson, A.C.1    Lord, G.M.2    Dardalhon, V.3
  • 14
    • 41249096396 scopus 로고    scopus 로고
    • The Tim-3 ligand galectin-9 negatively regulates CD8+ alloreactive T cells and prolongs survival of skin graft
    • Wang F, He W, Zhou H, et al. The Tim-3 ligand galectin-9 negatively regulates CD8+ alloreactive T cells and prolongs survival of skin graft. Cell Immunol. 2007;250(1-2):68-74.
    • (2007) Cell Immunol. , vol.250 , Issue.1-2 , pp. 68-74
    • Wang, F.1    He, W.2    Zhou, H.3
  • 17
    • 77549084480 scopus 로고    scopus 로고
    • Human pregnancy up-regulates Tim-3 in innate immune cells for systemic immunity
    • Zhao J, Lei Z, Liu Y, et al. Human pregnancy up-regulates Tim-3 in innate immune cells for systemic immunity. J Immunol. 2009;182(10):6618-6624.
    • (2009) J Immunol. , vol.182 , Issue.10 , pp. 6618-6624
    • Zhao, J.1    Lei, Z.2    Liu, Y.3
  • 19
    • 0031048272 scopus 로고    scopus 로고
    • Identification and characterization of galectin-9, a novel beta- galactoside-binding mammalian lectin
    • DOI 10.1074/jbc.272.9.6078
    • Wada J, Kanwar YS. Identification and characterization of galectin-9, a novel beta-galactoside-binding mammalian lectin. J Biol Chem. 1997;272(9):6078-86. (Pubitemid 27102450)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.9 , pp. 6078-6086
    • Wada, J.1    Kanwar, Y.S.2
  • 21
    • 58149277359 scopus 로고    scopus 로고
    • Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection
    • Jones RB, Ndhlovu LC, Barbour JD, et al. Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection. J. Exp. Med. 2008;205(12):2763-2779.
    • (2008) J. Exp. Med. , vol.205 , Issue.12 , pp. 2763-2779
    • Jones, R.B.1    Ndhlovu, L.C.2    Barbour, J.D.3
  • 23
    • 40849120400 scopus 로고    scopus 로고
    • Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis
    • Seki M, Oomizu S, Sakata KM, et al. Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis. Clin Immunol. 2008;127(1):78-88.
    • (2008) Clin Immunol. , vol.127 , Issue.1 , pp. 78-88
    • Seki, M.1    Oomizu, S.2    Sakata, K.M.3
  • 24
    • 79955977180 scopus 로고    scopus 로고
    • Coexpression of Tim-3 and PD-1 identifies a CD8+ T-cell exhaustion phenotype in mice with disseminated acute myelogenous leukemia
    • Zhou Q, Munger ME, Veenstra RG, et al. Coexpression of Tim-3 and PD-1 identifies a CD8+ T-cell exhaustion phenotype in mice with disseminated acute myelogenous leukemia. Blood. 2011;117(17):4501-4510.
    • (2011) Blood , vol.117 , Issue.17 , pp. 4501-4510
    • Zhou, Q.1    Munger, M.E.2    Veenstra, R.G.3
  • 25
    • 59249099786 scopus 로고    scopus 로고
    • Galectin-9 expands unique macrophages exhibiting plasmacytoid dendritic cell-like phenotypes that activate NK cells in tumor-bearing mice
    • Nobumoto A, Oomizu S, Arikawa T, et al. Galectin-9 expands unique macrophages exhibiting plasmacytoid dendritic cell-like phenotypes that activate NK cells in tumor-bearing mice. Clin Immunol. 2009;130(3):322-330.
    • (2009) Clin Immunol. , vol.130 , Issue.3 , pp. 322-330
    • Nobumoto, A.1    Oomizu, S.2    Arikawa, T.3
  • 27
    • 33646184966 scopus 로고    scopus 로고
    • Evaluation of ex vivo expanded human NK cells on anti-leukemia activity in SCID-beige mice
    • Guimaraes F, Guven H, Donati D, et al. Evaluation of ex vivo expanded human NK cells on anti-leukemia activity in SCID-beige mice. Leukemia. 2006;20(5):833-839.
    • (2006) Leukemia , vol.20 , Issue.5 , pp. 833-839
    • Guimaraes, F.1    Guven, H.2    Donati, D.3
  • 28
    • 60249098439 scopus 로고    scopus 로고
    • Donors with group B KIR haplotypes improve relapse-free survival after unrelated hematopoietic cell transplantation for acute myelogenous leukemia
    • Cooley S, Trachtenberg E, Bergemann TL, et al. Donors with group B KIR haplotypes improve relapse-free survival after unrelated hematopoietic cell transplantation for acute myelogenous leukemia. Blood. 2009;113(3):726-732.
    • (2009) Blood , vol.113 , Issue.3 , pp. 726-732
    • Cooley, S.1    Trachtenberg, E.2    Bergemann, T.L.3
  • 29
    • 77957734984 scopus 로고    scopus 로고
    • Donor selection for natural killer cell receptor genes leads to superior survival after unrelated transplantation for acute myelogenous leukemia
    • Cooley S, Weisdorf DJ, Guethlein LA, et al. Donor selection for natural killer cell receptor genes leads to superior survival after unrelated transplantation for acute myelogenous leukemia. Blood. 2010;116(14):2411-2419.
    • (2010) Blood , vol.116 , Issue.14 , pp. 2411-2419
    • Cooley, S.1    Weisdorf, D.J.2    Guethlein, L.A.3
  • 30
    • 18644385629 scopus 로고    scopus 로고
    • A requirement for CD45 distinguishes Ly49D-mediated cytokine and chemokine production from killing in primary natural killer cells
    • DOI 10.1084/jem.20042294
    • Huntington ND, Xu Y, Nutt SL, Tarlington DM. A requirement for CD45 distinguishes Ly49D-mediated cytokine and chemokine production from killing in primary natural killer cells. J Exp Med. 2005;201(9):1421-1433. (Pubitemid 40664086)
    • (2005) Journal of Experimental Medicine , vol.201 , Issue.9 , pp. 1421-1433
    • Huntington, N.D.1    Xu, Y.2    Nutt, S.L.3    Tarlinton, D.M.4
  • 32
    • 77949900365 scopus 로고    scopus 로고
    • T cell/transmembrane, Ig, and mucin-3 allelic variants differentially recognize phosphatidylserine and mediate phagocytosis of apoptotic cells
    • DeKruyff RH, Bu X, Ballesteros A, et al. T cell/transmembrane, Ig, and mucin-3 allelic variants differentially recognize phosphatidylserine and mediate phagocytosis of apoptotic cells. J Immunol. 2010;184(4):1918-1930.
    • (2010) J Immunol. , vol.184 , Issue.4 , pp. 1918-1930
    • DeKruyff, R.H.1    Bu, X.2    Ballesteros, A.3
  • 34
    • 0037313578 scopus 로고    scopus 로고
    • Interleukin-12 and the regulation of innate resistance and adaptive immunity
    • DOI 10.1038/nri1001
    • Trinchieri G. Interleukin-12 and the regulation of innate resistance and adaptive immunity. Nat Rev Immunol. 2003;3(2):133-146. (Pubitemid 37328691)
    • (2003) Nature Reviews Immunology , vol.3 , Issue.2 , pp. 133-146
    • Trinchieri, G.1
  • 35
    • 20844438187 scopus 로고    scopus 로고
    • NK-cell reconstitution after haploidentical hematopoietic stem-cell transplantations: Immaturity of NK cells and inhibitory effect of NKG2A override GvL effect
    • DOI 10.1182/blood-2004-10-4113
    • Nguyen S, Dhedin N, Vernant JP, et al. NK-cell reconstitution after haploidentical hematopoietic stem-cell transplantations: immaturity of NK cells and inhibitory effect of NKG2A override GvL effect. Blood. 2005;105(10):4135- 4142. (Pubitemid 40656166)
    • (2005) Blood , vol.105 , Issue.10 , pp. 4135-4142
    • Nguyen, S.1    Dhedin, N.2    Vernant, J.-P.3    Kuentz, M.4    Al, J.A.5    Rouas-Freiss, N.6    Carosella, E.D.7    Boudifa, A.8    Debre, P.9    Vieillard, V.10
  • 36
    • 77549086947 scopus 로고    scopus 로고
    • T cell immunoglobulin- and mucin-domain-containing molecule-3 (Tim-3) mediates natural killer suppression in chronic hepatitis B
    • Ju Y, Hou N, Meng J, et al. T cell immunoglobulin- and mucin-domain-containing molecule-3 (Tim-3) mediates natural killer suppression in chronic hepatitis B. J Hepatol. 2010;52(3):322-329.
    • (2010) J Hepatol. , vol.52 , Issue.3 , pp. 322-329
    • Ju, Y.1    Hou, N.2    Meng, J.3
  • 37
    • 71849095178 scopus 로고    scopus 로고
    • Galectin-9 increases Tim-3+ dendritic cells and CD8+ T cells and enhances anti-tumor immunity via galection-9-Tim-3 interactions
    • Nagahara K, Arikawa T, Oomizu S, et al. Galectin-9 increases Tim-3+ dendritic cells and CD8+ T cells and enhances anti-tumor immunity via galection-9-Tim-3 interactions. J. Immunol. 2008;181(11):7660-7669.
    • (2008) J. Immunol. , vol.181 , Issue.11 , pp. 7660-7669
    • Nagahara, K.1    Arikawa, T.2    Oomizu, S.3
  • 38
    • 65549147768 scopus 로고    scopus 로고
    • Blockade of Tim-3 pathway ameliorates interferon-gamma production from hepatic CD8+ T cells in a mouse model of hepatitis B virus infection
    • Ju Y, Hou N, Zhang XN, et al. Blockade of Tim-3 pathway ameliorates interferon-gamma production from hepatic CD8+ T cells in a mouse model of hepatitis B virus infection. Cell Mol Immunol. 2009;6(1):35-43.
    • (2009) Cell Mol Immunol. , vol.6 , Issue.1 , pp. 35-43
    • Ju, Y.1    Hou, N.2    Zhang, X.N.3
  • 39
    • 80053608320 scopus 로고    scopus 로고
    • Phosphotyrosine-dependent coupling of tim-3 to T-cell receptor signaling pathways
    • Lee J, Su EW, Zhu C, et al. Phosphotyrosine-dependent coupling of tim-3 to T-cell receptor signaling pathways. Mol Cell Biol. 2011;31(19):3963-3974.
    • (2011) Mol Cell Biol. , vol.31 , Issue.19 , pp. 3963-3974
    • Lee, J.1    Su, E.W.2    Zhu, C.3
  • 42
    • 20444389785 scopus 로고    scopus 로고
    • Molecular basis for positive and negative signaling by the natural killer cell receptor 2B4 (CD244)
    • DOI 10.1182/blood-2004-09-3796
    • Eissmann P, Beauchamp L, Wooters J, Tilton JC, Long EO, Watzl C. Molecular basis for positive and negative signaling by the natural killer cell receptor 2B4 (CD244). Blood. 2005;105(12):4722-4729. (Pubitemid 40807295)
    • (2005) Blood , vol.105 , Issue.12 , pp. 4722-4729
    • Eissmann, P.1    Beauchamp, L.2    Wooters, J.3    Tilton, J.C.4    Long, E.O.5    Watzl, C.6
  • 44
    • 0035881573 scopus 로고    scopus 로고
    • Cutting edge: Induction of IFN-gamma production but not cytotoxicity by the killer cell Ig-like receptor KIR2DL4 (CD158d) in resting NK cells
    • Rajagopalan S, Fu J, Long EO. Cutting edge: induction of IFN-gamma production but not cytotoxicity by the killer cell Ig-like receptor KIR2DL4 (CD158d) in resting NK cells. J Immunol. 2001;67(4):1877-1881. (Pubitemid 32747490)
    • (2001) Journal of Immunology , vol.167 , Issue.4 , pp. 1877-1881
    • Rajagopalan, S.1    Fu, J.2    Long, E.O.3
  • 45
    • 0035575998 scopus 로고    scopus 로고
    • 2B4 (CD244)-mediated activation of cytotoxicity and IFN-gamma release in human NK cells involves distinct pathways
    • Chuang SS, Kumaresan PR, Mathew PA. 2B4 (CD244)-mediated activation of cytotoxicity and IFN-gamma release in human NK cells involves distinct pathways. J Immunol. 2001;167(11):6210-6216. (Pubitemid 33081549)
    • (2001) Journal of Immunology , vol.167 , Issue.11 , pp. 6210-6216
    • Chuang, S.S.1    Kumaresan, P.R.2    Mathew, P.A.3
  • 46
    • 0030727981 scopus 로고    scopus 로고
    • IL-12-induced tumor regression correlates with in situ activity of IFN- gamma produced by tumor-infiltrating cells and its secondary induction of anti- tumor pathways
    • Yu WG, Ogawa M, Mu J, et al. IL-12-induced tumor regression correlates with in situ activity of IFN-gamma produced by tumor-infiltrating cells and its secondary induction of anti-tumor pathways. J Leukoc Biol. 1997;62(4):450-457. (Pubitemid 27459773)
    • (1997) Journal of Leukocyte Biology , vol.62 , Issue.4 , pp. 450-457
    • Yu, W.-G.1    Ogawa, M.2    Mu, J.3    Umehara, K.4    Tsujimura, T.5    Fujiwara, H.6    Hamaoka, T.7
  • 47
    • 0032518668 scopus 로고    scopus 로고
    • Interferon-induces expression of cyclin-dependent kinase-inhibitors p21(WAF1) and p27(Kip1) that prevent activation of cyclin-dependent kinase by CDK-activating kinase (CAK)
    • Mandal M, Bandyopadhyay D, Goepfert TM, Kumar R. Interferon-induces expression of cyclin-dependent kinase-inhibitors p21WAF1 and p27Kip1 that prevent activation of cyclin-dependent kinase by CDK-activating kinase (CAK). Oncogene. 1998;16(2):217-225. (Pubitemid 28045108)
    • (1998) Oncogene , vol.16 , Issue.2 , pp. 217-225
    • Mandal, M.1    Bandyopadhyay, D.2    Goepfert, T.M.3    Kumar, R.4
  • 48
    • 0032125574 scopus 로고    scopus 로고
    • IFN-gamma induces cell growth inhibition by fas-mediated apoptosis: Requirement of STAT1 protein for up-regulation of Fas and FasL expression
    • Xu X, Fu XY, Plate J, Chong AS. IFN-gamma induces cell growth inhbition by Fas-mediated apoptosis: requirement of STAT1 protein for up-regulation of Fas and FasL expression. Cancer Res. 1998;58(13):2832-2837. (Pubitemid 28311915)
    • (1998) Cancer Research , vol.58 , Issue.13 , pp. 2832-2837
    • Xu, X.1    Fu, X.-Y.2    Plate, J.3    Chong, A.S.-F.4
  • 49
    • 77950383116 scopus 로고    scopus 로고
    • Hematopoietic cell transplantation for adult acute myeloid leukemia
    • Appelbaum FR, Forman SJ, Negrin RS, Blume KG, eds. 4th ed. Malden, MA: Blackwell Publishing
    • Appelbaum FR. Hematopoietic cell transplantation for adult acute myeloid leukemia. In: Appelbaum FR, Forman SJ, Negrin RS, Blume KG, eds. Thomas' Hematopoietic Cell Transplantation: Stem Cell Transplantation, 4th ed. Malden, MA: Blackwell Publishing; 2009:761-774.
    • (2009) Thomas' Hematopoietic Cell Transplantation: Stem Cell Transplantation , pp. 761-774
    • Appelbaum, F.R.1


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