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Volumn 48, Issue 4, 2012, Pages 589-599

Quercetin: A flavonoid with the potential to treat asthma

Author keywords

Asthma; Flavonoids; Quercetin

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; COLLAGEN TYPE 3; CORTICOSTEROID; GINKGO BILOBA EXTRACT; HYPERICUM PERFORATUM EXTRACT; IMMUNOGLOBULIN E; ISOQUERCITRIN; LEUKOTRIENE RECEPTOR BLOCKING AGENT; MONTELUKAST; PRANLUKAST; QUERCETIN; SALBUTAMOL; ZAFIRLUKAST; ZILEUTON;

EID: 84874285811     PISSN: 19848250     EISSN: 21759790     Source Type: Journal    
DOI: 10.1590/S1984-82502012000400002     Document Type: Review
Times cited : (29)

References (92)
  • 1
    • 77954620216 scopus 로고    scopus 로고
    • A further investigation concerning correlation between anti-fibrotic effect of liposomal quercetin and inflammatory cytokines in pulmonary fibrosis
    • BAOWEN, Q.; YULIN, Z.; XIN, W.; WENJING, X.; HAO, Z.; ZHIZHI, C.; XINGMEI, D.; XIA, Z.; YUQUAN, W.; LIJUAN, C. A further investigation concerning correlation between anti-fibrotic effect of liposomal quercetin and inflammatory cytokines in pulmonary fibrosis. Eur. J. Pharmacol., v.642, n.1-3, p.134-139, 2010.
    • (2010) Eur. J. Pharmacol. , vol.642 , Issue.1-3 , pp. 134-139
    • Baowen, Q.1    Yulin, Z.2    Xin, W.3    Wenjing, X.4    Hao, Z.5    Zhizhi, C.6    Xingmei, D.7    Xia, Z.8    Yuquan, W.9    Lijuan, C.10
  • 2
    • 0031862891 scopus 로고    scopus 로고
    • Anti-inflammatory actions of glucocorticoids: Molecular mechanisms
    • BARNES, P.J. Anti-inflammatory actions of glucocorticoids: molecular mechanisms. Clin. Sci., v.94, n.6, p.557-572, 1998.
    • (1998) Clin. Sci. , vol.94 , Issue.6 , pp. 557-572
    • Barnes, P.J.1
  • 3
    • 33744477341 scopus 로고    scopus 로고
    • How corticosteroids control inflammation: Quintiles prize lecture 2005
    • BARNES, P.J. How corticosteroids control inflammation: quintiles prize lecture 2005. Br. J. Pharmacol., v.148, n.3, p.245-254, 2006.
    • (2006) Br. J. Pharmacol. , vol.148 , Issue.3 , pp. 245-254
    • Barnes, P.J.1
  • 4
    • 79959334504 scopus 로고    scopus 로고
    • Pathophysiology of allergic inflammation
    • BARNES, P.J. Pathophysiology of allergic inflammation. Immunol. Rev., v.242, n.1, p.31-50, 2011.
    • (2011) Immunol. Rev. , vol.242 , Issue.1 , pp. 31-50
    • Barnes, P.J.1
  • 5
    • 0036224523 scopus 로고    scopus 로고
    • Increased release of matrix metalloproteinase-9 in the plasma of acute severe asthmatic patients
    • BELLEGUIC, C.; CORBEL, M.; GERMAIN, N.; LÉNA, H.; BOICHOT, E.; DELAVAL, P.H.; LAGENTE, V. Increased release of matrix metalloproteinase-9 in the plasma of acute severe asthmatic patients. Clin. Exp. Allergy, v.32, n.2, p.217-223, 2002.
    • (2002) Clin. Exp. Allergy , vol.32 , Issue.2 , pp. 217-223
    • Belleguic, C.1    Corbel, M.2    Germain, N.3    Léna, H.4    Boichot, E.5    Delaval, P.H.6    Lagente, V.7
  • 6
    • 0033582285 scopus 로고    scopus 로고
    • Involvement of regulatory and catalytic subunits of phosphoinositide 3-kinase in NF-kappa B activation
    • BÉRAUD, C.; HENZEL, W.J.; BAEUERLE, P.A. Involvement of regulatory and catalytic subunits of phosphoinositide 3-kinase in NF-kappa B activation. Proc. Natl. Acad. Sci. USA, v.96, n.2, p.429-434, 1999.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , Issue.2 , pp. 429-434
    • Béraud, C.1    Henzel, W.J.2    Baeuerle, P.A.3
  • 8
    • 0033778159 scopus 로고    scopus 로고
    • Is allergic asthma associated with delayed fetal maturation or the persistence of conserved fetal genes?
    • BOUSQUET, J.; YSSEL, H.; VIGNOLA, A.M. Is allergic asthma associated with delayed fetal maturation or the persistence of conserved fetal genes? Allergy, v.55, n.12, p.1194-1197, 2000.
    • (2000) Allergy , vol.55 , Issue.12 , pp. 1194-1197
    • Bousquet, J.1    Yssel, H.2    Vignola, A.M.3
  • 10
    • 0346059349 scopus 로고    scopus 로고
    • Anti-inflammatory compounds of plant origin. Part II. Modulation of pro-inflammatory cytokines, chemokines and adhesion molecules
    • CALIXTO, J.B.; CAMPOS, M.M.; OTUKI, M.F.; SANTOS, A.R. Anti-inflammatory compounds of plant origin. Part II. Modulation of pro-inflammatory cytokines, chemokines and adhesion molecules. Planta Med., v.69, n.2, p.973-983, 2004.
    • (2004) Planta Med. , vol.69 , Issue.2 , pp. 973-983
    • Calixto, J.B.1    Campos, M.M.2    Otuki, M.F.3    Santos, A.R.4
  • 11
    • 76949106982 scopus 로고    scopus 로고
    • The efficacy of Hypericum perforatum (St John's wort) for the treatment of premenstrual syndrome: A randomized, double-blind, placebo-controlled trial
    • CANNING, S.; WATERMAN, M.; ORSI, N.; AYRES, J.; SIMPSON, N.; DYE, L. The efficacy of Hypericum perforatum (St John's wort) for the treatment of premenstrual syndrome: a randomized, double-blind, placebo-controlled trial. CNS Drugs, v.24, n.3, p.207-225, 2010.
    • (2010) CNS Drugs , vol.24 , Issue.3 , pp. 207-225
    • Canning, S.1    Waterman, M.2    Orsi, N.3    Ayres, J.4    Simpson, N.5    Dye, L.6
  • 12
    • 23744435643 scopus 로고    scopus 로고
    • Inhaled beta2-adrenoceptor agonists: Cardiovascular safety in patients with obstructive lung disease
    • CAZZOLA, M.; MATERA, M.G.; DONNER, C.F. Inhaled beta2-adrenoceptor agonists: cardiovascular safety in patients with obstructive lung disease. Drugs, v.65, n.12, p.1595-1610, 2005.
    • (2005) Drugs , vol.65 , Issue.12 , pp. 1595-1610
    • Cazzola, M.1    Matera, M.G.2    Donner, C.F.3
  • 13
    • 77950897478 scopus 로고    scopus 로고
    • Dietary polyphenols affect MUC5AC expression and ciliary movement in respiratory cells and nasal mucosa
    • CHANG, J.H.; SONG, K.J.; KIM, H.J.; KIM, J.H.; KIM, N.H.; KIM, K.S. Dietary polyphenols affect MUC5AC expression and ciliary movement in respiratory cells and nasal mucosa. Am. J. Rhinol. Allergy, v.24, n.2, p.59-62, 2010.
    • (2010) Am. J. Rhinol. Allergy , vol.24 , Issue.2 , pp. 59-62
    • Chang, J.H.1    Song, K.J.2    Kim, H.J.3    Kim, J.H.4    Kim, N.H.5    Kim, K.S.6
  • 14
    • 34548364183 scopus 로고    scopus 로고
    • Acute severe asthma: Triage, treatment and thereafter current
    • CHUA, F.; LAI, D. Acute severe asthma: Triage, treatment and thereafter current. Current Anaesthesia & Critical Care, v.18, n.2, p.61-68, 2007.
    • (2007) Current Anaesthesia & Critical Care , vol.18 , Issue.2 , pp. 61-68
    • Chua, F.1    Lai, D.2
  • 15
    • 0023925747 scopus 로고
    • Human eosinophil hematopoiesis studied in vitro by means of murine eosinophil differentiation factor [IL5]: Production of functionally active eosinophils from normal human bone marrow
    • CLUTTERBUCK, E.J.; SANDERSON, C.J. Human eosinophil hematopoiesis studied in vitro by means of murine eosinophil differentiation factor [IL5]: production of functionally active eosinophils from normal human bone marrow. Blood, v.71, n.3, p.646-651, 1988.
    • (1988) Blood , vol.71 , Issue.3 , pp. 646-651
    • Clutterbuck, E.J.1    Sanderson, C.J.2
  • 19
    • 74949133831 scopus 로고    scopus 로고
    • Serum lipid and blood pressure responses to quercetin vary in overweight patients by apolipoprotein e genotype
    • EGERT, S.; BOESCH-SAADATMANDI, C.; WOLFFRAM, S.; RIMBACH, G.; MULLER M.J. Serum lipid and blood pressure responses to quercetin vary in overweight patients by apolipoprotein e genotype. J. Nutr., v.140, n.2, p.278-284, 2010.
    • (2010) J. Nutr. , vol.140 , Issue.2 , pp. 278-284
    • Egert, S.1    Boesch-Saadatmandi, C.2    Wolffram, S.3    Rimbach, G.4    Muller, M.J.5
  • 20
    • 0029988623 scopus 로고    scopus 로고
    • IL-5 drives eosinophils from bone marrow to blood and tissues in a guinea-pig model of visceral larva migrans syndrome
    • FACCIOLI, L.H.; MOKWA, V.F.; SILVA C.L.; ROCHA, G.M.; ARAUJO, J.I.; NAHORI, M.A.; VARGAFTIG, B.B. IL-5 drives eosinophils from bone marrow to blood and tissues in a guinea-pig model of visceral larva migrans syndrome. Mediators Inflamm., v.5, n.1, p.24-31, 1996.
    • (1996) Mediators Inflamm. , vol.5 , Issue.1 , pp. 24-31
    • Faccioli, L.H.1    Mokwa, V.F.2    Silva, C.L.3    Rocha, G.M.4    Araujo, J.I.5    Nahori, M.A.6    Vargaftig, B.B.7
  • 21
    • 0023751736 scopus 로고
    • Eleventh Gaddum memorial lecture. Lipocortin and the mechanism of action of the glucocorticoids
    • FLOWER, R.J. Eleventh Gaddum memorial lecture. Lipocortin and the mechanism of action of the glucocorticoids. Br. J. Pharmacol., v.94, n.4, p.987-1015, 1988.
    • (1988) Br. J. Pharmacol. , vol.94 , Issue.4 , pp. 987-1015
    • Flower, R.J.1
  • 23
    • 0011892526 scopus 로고
    • The receptor for immunoglobulin E on rat basophilic leukemia cells: Effect of ligand binding on receptor expression
    • FURUICHI, K.; RIVERA, J.; ISERSKY, C. The receptor for immunoglobulin E on rat basophilic leukemia cells: Effect of ligand binding on receptor expression. Proc. Natl. Acad. Sci. USA, v.82, n.5, p.1522-1525, 1985.
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , Issue.5 , pp. 1522-1525
    • Furuichi, K.1    Rivera, J.2    Isersky, C.3
  • 26
    • 40049101678 scopus 로고    scopus 로고
    • IgE in allergy and asthma today
    • GOULD, H.J.; SUTTON, B.J. IgE in allergy and asthma today. Nat. Rev. Immunol, v.8, n.3, p.205-217, 2008.
    • (2008) Nat. Rev. Immunol , vol.8 , Issue.3 , pp. 205-217
    • Gould, H.J.1    Sutton, B.J.2
  • 27
    • 25144495954 scopus 로고    scopus 로고
    • Designing and testing of an effective oil-in-water microemulsion drug delivery system for in vivo application
    • GUPTA, S.; MOULIK, S.P.; LALA, S.; BASU, M.K.; SANYAL, S.K.; DATTA, S. Designing and testing of an effective oil-in-water microemulsion drug delivery system for in vivo application. Drug Deliv., v.12, n.5, p.267-273, 2005.
    • (2005) Drug Deliv , vol.12 , Issue.5 , pp. 267-273
    • Gupta, S.1    Moulik, S.P.2    Lala, S.3    Basu, M.K.4    Sanyal, S.K.5    Datta, S.6
  • 28
    • 0015294626 scopus 로고
    • Comparison of the effect on blood gases, ventilation, and perfusion of isoproterenol-phenylephrine and salbutamol aerosols in chronic bronchitis with asthma
    • HARRIS, L. Comparison of the effect on blood gases, ventilation, and perfusion of isoproterenol-phenylephrine and salbutamol aerosols in chronic bronchitis with asthma. J. Allergy Clin. Immunol., v.49, n.2, p.63-71, 1972.
    • (1972) J. Allergy Clin. Immunol , vol.49 , Issue.2 , pp. 63-71
    • Harris, L.1
  • 29
    • 34548812546 scopus 로고    scopus 로고
    • A critical review of the data related to the safety of quercetin and lack of evidence of in vivo toxicity, including lack of genotoxic/carcinogenic properties
    • HARWOOD, M.; DANIELEWSKA-NIKIEL, B.; BORZELLECA, J.F.; FLAMM, G.W.; WILLIAMS, G.M.; LINES, T.C. A critical review of the data related to the safety of quercetin and lack of evidence of in vivo toxicity, including lack of genotoxic/carcinogenic properties. Food Chem. Toxicol., v.45, n.11, p.2179-2205, 2007.
    • (2007) Food Chem. Toxicol , vol.45 , Issue.11 , pp. 2179-2205
    • Harwood, M.1    Danielewska-Nikiel, B.2    Borzelleca, J.F.3    Flamm, G.W.4    Williams, G.M.5    Lines, T.C.6
  • 30
    • 40049092917 scopus 로고    scopus 로고
    • Treatment strategies for allergy and asthma
    • HOLGATE, S.T.; POLOSA, R. Treatment strategies for allergy and asthma. Nat. Rev. Immunol., v.8, n.3, p.218-230, 2008.
    • (2008) Nat. Rev. Immunol. , vol.8 , Issue.3 , pp. 218-230
    • Holgate, S.T.1    Polosa, R.2
  • 31
    • 0028793218 scopus 로고
    • Absorption of dietary quercetin glycosides and quercetin in healthy ileostomy volunteers
    • HOLLMAN, P.C.; DE VRIES, J.H.; VAN LEEUWEN, S.D.; MENGELERS, M.J.; KATAN, M.B. Absorption of dietary quercetin glycosides and quercetin in healthy ileostomy volunteers. Am. J. Clin. Nutr., v.62, n.6, p.1276-1282, 1995.
    • (1995) Am. J. Clin. Nutr , vol.62 , Issue.6 , pp. 1276-1282
    • Hollman, P.C.1    de Vries, J.H.2    van Leeuwen, S.D.3    Mengelers, M.J.4    Katan, M.B.5
  • 33
    • 35348836037 scopus 로고    scopus 로고
    • Potent suppressive effects of 3-O-methylquercetin 5,7,3',4'-O-tetraacetate on ovalbumin-induced airway hyperresponsiveness
    • JIANG, J.S.; CHIEN, H.C.; CHEN, C.M.; LIN, C.N.; KO, W.C. Potent suppressive effects of 3-O-methylquercetin 5,7,3',4'-O-tetraacetate on ovalbumin-induced airway hyperresponsiveness. Planta Med., v.73, n.11, p.1156-1162, 2007.
    • (2007) Planta Med. , vol.73 , Issue.11 , pp. 1156-1162
    • Jiang, J.S.1    Chien, H.C.2    Chen, C.M.3    Lin, C.N.4    Ko, W.C.5
  • 35
    • 78751626255 scopus 로고    scopus 로고
    • Acute bronchodilator effect of quercetin in experimental allergic asthma
    • JOSKOVA, M.; FRANOVA, S.; SADLONOVA, V. Acute bronchodilator effect of quercetin in experimental allergic asthma. Bratisl. Lek. Listy, v.112, n.1, p.9-12, 2011.
    • (2011) Bratisl. Lek. Listy , vol.112 , Issue.1 , pp. 9-12
    • Joskova, M.1    Franova, S.2    Sadlonova, V.3
  • 36
    • 38049184767 scopus 로고    scopus 로고
    • Anti-asthmatic action of quercetin and rutin in conscious guinea-pigs challenged with aerosolized ovalbumin
    • JUNG, C.H.; LEE, J.Y.; CHO, C.H.; KIM, C.J. Anti-asthmatic action of quercetin and rutin in conscious guinea-pigs challenged with aerosolized ovalbumin. Arch. Pharm. Res., v.30, n.12, p.1599-1607, 2007.
    • (2007) Arch. Pharm. Res. , vol.30 , Issue.12 , pp. 1599-1607
    • Jung, C.H.1    Lee, J.Y.2    Cho, C.H.3    Kim, C.J.4
  • 37
    • 23744474477 scopus 로고    scopus 로고
    • Flavonols inhibit proinflammatory mediator release, intracellular calcium ion levels and protein kinase C theta phosphorylation in human mast cells
    • KEMPURAJ, D.; MADHAPPAN, B.; CHRISTODOULOU, S.; BOUCHER, W.; CAO, J.; PAPADOPOULOU, N.; CETRULO, C.L.; THEOHARIDES T.C. Flavonols inhibit proinflammatory mediator release, intracellular calcium ion levels and protein kinase C theta phosphorylation in human mast cells. Br. J. Pharmacol., v.145, n.7, p.934-944, 2005.
    • (2005) Br. J. Pharmacol. , vol.145 , Issue.7 , pp. 934-944
    • Kempuraj, D.1    Madhappan, B.2    Christodoulou, S.3    Boucher, W.4    Cao, J.5    Papadopoulou, N.6    Cetrulo, C.L.7    Theoharides, T.C.8
  • 39
    • 11944259107 scopus 로고    scopus 로고
    • Suppressive effects of 3-O-methylquercetin on ovalbumin-induced airway hyperresponsiveness
    • KO, W.C.; SHIH, C.M.; CHEN, M.C.; LAI, Y.H.; CHEN, J.H.; CHEN, C.M.; LIN, C.N. Suppressive effects of 3-O-methylquercetin on ovalbumin-induced airway hyperresponsiveness. Planta Med., v.70, n.12, p.1123-1127, 2004.
    • (2004) Planta Med. , vol.70 , Issue.12 , pp. 1123-1127
    • Ko, W.C.1    Shih, C.M.2    Chen, M.C.3    Lai, Y.H.4    Chen, J.H.5    Chen, C.M.6    Lin, C.N.7
  • 40
  • 41
    • 78649516124 scopus 로고    scopus 로고
    • Functions of T cells in asthma: More than just Th2 cells
    • LLOYD, C.M.; HESSEL, E.M. Functions of T cells in asthma: more than just Th2 cells. Nat. Rev. Immunol., v.10, n.12, p.838-848, 2010.
    • (2010) Nat. Rev. Immunol. , vol.10 , Issue.12 , pp. 838-848
    • Lloyd, C.M.1    Hessel, E.M.2
  • 42
    • 33750410957 scopus 로고    scopus 로고
    • Influence of quercetin and x-ray on collagen synthesis of cultured human keloid-derived fibroblasts
    • LONG, X.; ZENG, X.; ZHANG, F.Q.; WANG, X.J. Influence of quercetin and x-ray on collagen synthesis of cultured human keloid-derived fibroblasts. Chin. Med. Sci. J., v.21, n.3, p.179-183, 2006.
    • (2006) Chin. Med. Sci. J. , vol.21 , Issue.3 , pp. 179-183
    • Long, X.1    Zeng, X.2    Zhang, F.Q.3    Wang, X.J.4
  • 43
    • 43849110089 scopus 로고    scopus 로고
    • Glucocorticoids and fatty acid metabolism in humans: Fuelling fat redistribution in the metabolic syndrome
    • MACFARLANE, D.P.; FORBES, S.; WALKER, B.R. Glucocorticoids and fatty acid metabolism in humans: fuelling fat redistribution in the metabolic syndrome. J. Endocrinol., v.197, n.2, p.189-204, 2008.
    • (2008) J. Endocrinol. , vol.197 , Issue.2 , pp. 189-204
    • McFarlane, D.P.1    Forbes, S.2    Walker, B.R.3
  • 44
    • 0035379555 scopus 로고    scopus 로고
    • Akt stimulates the transactivation potential of the RelA/p65 subunit of NF-kappa B through utilization of the I kappa B kinase and activation of the mitogen-activated protein kinase p38
    • MADRID, L.V.; MAYO, M.W.; REUTHER, J.Y.; BALDWIN JR, A.S. Akt stimulates the transactivation potential of the RelA/p65 subunit of NF-kappa B through utilization of the I kappa B kinase and activation of the mitogen-activated protein kinase p38. J. Biol. Chem., v.276, n.22, p.18934-18940, 2001.
    • (2001) J. Biol. Chem. , vol.276 , Issue.22 , pp. 18934-18940
    • Madrid, L.V.1    Mayo, M.W.2    Reuther, J.Y.3    Baldwin Jr., A.S.4
  • 45
    • 0001744937 scopus 로고
    • Cause of death and pathological findings in 304 cases of bronchial asthma
    • MESSER, J.; PETERS, G.A.; BENNET, W.A. Cause of death and pathological findings in 304 cases of bronchial asthma. Chest, v.38, p.616-624, 1960.
    • (1960) Chest , vol.38 , pp. 616-624
    • Messer, J.1    Peters, G.A.2    Bennet, W.A.3
  • 46
    • 0033637140 scopus 로고    scopus 로고
    • The effects of plant flavonoids on mammalian cells: Implications for inflammation, heart disease, and cancer
    • MIDDLETON, E.; CHITHAN, K.; THEOHARIDES, T.C. The effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease, and cancer. Pharmacol. Rev., v.52, n.4, p.673-751, 2000.
    • (2000) Pharmacol. Rev. , vol.52 , Issue.4 , pp. 673-751
    • Middleton, E.1    Chithan, K.2    Theoharides, T.C.3
  • 47
    • 34250816264 scopus 로고    scopus 로고
    • Quercetin inhibits expression of inflammatory cytokines through attenuation of NF-kappaB and p38 MAPK in HMC-1 human mast cell line
    • MIN, Y.D.; CHOI, C.H.; BARK, H.; SON, H.Y.; PARK, H.H.; LEE, S.; PARK, J.W.; PARK, E.K.; SHIN, H.I.; KIM, S.H. Quercetin inhibits expression of inflammatory cytokines through attenuation of NF-kappaB and p38 MAPK in HMC-1 human mast cell line. Inflamm. Res., v.56, n.5, p.210-215, 2007.
    • (2007) Inflamm. Res. , vol.56 , Issue.5 , pp. 210-215
    • Min, Y.D.1    Choi, C.H.2    Bark, H.3    Son, H.Y.4    Park, H.H.5    Lee, S.6    Park, J.W.7    Park, E.K.8    Shin, H.I.9    Kim, S.H.10
  • 48
    • 34247392438 scopus 로고    scopus 로고
    • Pharmacological modulation of the leukotriene pathway in allergic airway disease
    • MONTUSCHI, P.; SALA, A.; DAHLEN, S.E.; FOLCO, G. Pharmacological modulation of the leukotriene pathway in allergic airway disease. Drug Discov. Today, v.12, n.9-10, p.404-412, 2007.
    • (2007) Drug Discov. Today , vol.12 , Issue.9-10 , pp. 404-412
    • Montuschi, P.1    Sala, A.2    Dahlen, S.E.3    Folco, G.4
  • 49
    • 45749088175 scopus 로고    scopus 로고
    • Quercetin inhalation inhibits the asthmatic responses by exposure to aerosolized-ovalbumin in conscious guinea-pigs
    • MOON, H.; CHOI, H.H.; LEE, J.Y.; MOON, H.J.; SIM, S.S.; KIM, C.J. Quercetin inhalation inhibits the asthmatic responses by exposure to aerosolized-ovalbumin in conscious guinea-pigs. Arch. Pharm. Res., v.31, n.6, p.771-778, 2008.
    • (2008) Arch. Pharm. Res. , vol.31 , Issue.6 , pp. 771-778
    • Moon, H.1    Choi, H.H.2    Lee, J.Y.3    Moon, H.J.4    Sim, S.S.5    Kim, C.J.6
  • 50
    • 80053030747 scopus 로고    scopus 로고
    • Allergic Asthma: Influence of Genetic and Environmental Factors
    • MUKHERJEE, A.B.; ZHANG, Z. Allergic Asthma: Influence of Genetic and Environmental Factors. J. Biol. Chem., v.286, n.38, p.32883-32889, 2011.
    • (2011) J. Biol. Chem. , vol.286 , Issue.38 , pp. 32883-32889
    • Mukherjee, A.B.1    Zhang, Z.2
  • 52
    • 33746862576 scopus 로고    scopus 로고
    • Naturally occurring NF-kappa B inhibitors
    • NAM, N.H. Naturally occurring NF-kappa B inhibitors. Mini Rev. Med. Chem., v.6, n.8, p.945-951, 2006.
    • (2006) Mini Rev. Med. Chem. , vol.6 , Issue.8 , pp. 945-951
    • Nam, N.H.1
  • 54
    • 0004002716 scopus 로고    scopus 로고
    • Guidelines for the diagnosis and management of asthma
    • NATIONAL INSTITUTES OF HEALTH. NIH., National Heart and Lung, and Blood Institute., Bethesda,. (NIH Publication, no.9740-51)
    • NATIONAL INSTITUTES OF HEALTH. NIH. National Heart and Lung, and Blood Institute. Guidelines for the diagnosis and management of asthma. Expert Panel Report 2. Bethesda, 1997. (NIH Publication, no.9740-51). 134 p.
    • (1997) Expert Panel Report 2 , pp. 134
  • 55
    • 32944472519 scopus 로고    scopus 로고
    • Safety of quercetin for clinical application (Review)
    • OKAMOTO, T. Safety of quercetin for clinical application (Review). Int. J. Mol. Med., v.16, n.2, p.275-278, 2005.
    • (2005) Int. J. Mol. Med. , vol.16 , Issue.2 , pp. 275-278
    • Okamoto, T.1
  • 56
    • 72049132604 scopus 로고    scopus 로고
    • Acute severe asthma: New approaches to assessment and treatment
    • PAPIRIS, S.A.; MANALI, E.D.; KOLILEKAS, L.; TRIANTAFILLIDOU, C.; TSANGARIS, I. Acute severe asthma: new approaches to assessment and treatment. Drugs, v.69, n.17, p.2363-2391, 2009.
    • (2009) Drugs , vol.69 , Issue.17 , pp. 2363-2391
    • Papiris, S.A.1    Manali, E.D.2    Kolilekas, L.3    Triantafillidou, C.4    Tsangaris, I.5
  • 60
    • 0027284754 scopus 로고
    • Modulation of IL-1-induced neutrophil migration by dexamethasone and lipocortin1
    • PERRETTI, M.; FLOWER, R.J. Modulation of IL-1-induced neutrophil migration by dexamethasone and lipocortin1. J. Immunol., v.150, n.3, p.992-999, 1993.
    • (1993) J. Immunol. , vol.150 , Issue.3 , pp. 992-999
    • Perretti, M.1    Flower, R.J.2
  • 62
    • 0033859612 scopus 로고    scopus 로고
    • Flavonoids as antioxidants-review
    • PIETTA, P.G. Flavonoids as antioxidants-review. J. Nat. Prod., v.63, n.7, p.1035-1042, 2000.
    • (2000) J. Nat. Prod. , vol.63 , Issue.7 , pp. 1035-1042
    • Pietta, P.G.1
  • 63
    • 38449106795 scopus 로고    scopus 로고
    • Drug discovery and development with plant-derived compounds
    • POTTERAT, O.; HAMBURGER, M. Drug discovery and development with plant-derived compounds. Prog. Drug Res., v.65, n.45, p.47-118, 2008.
    • (2008) Prog. Drug Res. , vol.65 , Issue.45 , pp. 47-118
    • Potterat, O.1    Hamburger, M.2
  • 64
    • 0042337278 scopus 로고    scopus 로고
    • Antifibrotic effects of genistein and quercetin in vitro
    • QI, L.H.; KANG, L.P.; ZHANG, J.P.; SHI, N.; ZHANG, M.; WU, T.M. Antifibrotic effects of genistein and quercetin in vitro. Yao Xue Xue Bao, v.36, n.9, p.648-651, 2001.
    • (2001) Yao Xue Xue Bao , vol.36 , Issue.9 , pp. 648-651
    • Qi, L.H.1    Kang, L.P.2    Zhang, J.P.3    Shi, N.4    Zhang, M.5    Wu, T.M.6
  • 66
    • 33750620057 scopus 로고    scopus 로고
    • Oxidative stress and redox regulation of lung inflammation in COPD
    • RAHMAN, I.; ADCOCK, I.M. Oxidative stress and redox regulation of lung inflammation in COPD. Eur. Respir. J., v.28, n.1, p.219-242, 2006.
    • (2006) Eur. Respir. J. , vol.28 , Issue.1 , pp. 219-242
    • Rahman, I.1    Adcock, I.M.2
  • 68
    • 77649336979 scopus 로고    scopus 로고
    • Anti-inflammatory effect of quercetin-loaded microemulsion in the airways allergic inflammatory model in mice
    • ROGERIO, A.P.; DORA, C.L.; ANDRADE, E.L.; CHAVES, J.S.; SILVA, L.F.; LEMOS-SENNA, E.; CALIXTO, J.B. Anti-inflammatory effect of quercetin-loaded microemulsion in the airways allergic inflammatory model in mice. Pharmacol. Res., v.61, n.4, p.288-297, 2010.
    • (2010) Pharmacol. Res. , vol.61 , Issue.4 , pp. 288-297
    • Rogerio, A.P.1    Dora, C.L.2    Andrade, E.L.3    Chaves, J.S.4    Silva, L.F.5    Lemos-Senna, E.6    Calixto, J.B.7
  • 70
    • 77955279924 scopus 로고    scopus 로고
    • The activity of medicinal plants and secondary metabolites on eosinophilic inflammation
    • ROGERIO, A.P.; SÁ-NUNES, A.; FACCIOLI, L.H. The activity of medicinal plants and secondary metabolites on eosinophilic inflammation. Pharmacol. Res., v.62, n.4, p.298-307, 2010.
    • (2010) Pharmacol. Res. , vol.62 , Issue.4 , pp. 298-307
    • Rogerio, A.P.1    Sá-Nunes, A.2    Faccioli, L.H.3
  • 71
    • 0036247211 scopus 로고    scopus 로고
    • Cytokines and chemoattractants in allergic inflammation
    • ROMAGNANI, S. Cytokines and chemoattractants in allergic inflammation. Mol. Immunol., v.38, n.12-13, p.881-885, 2002.
    • (2002) Mol. Immunol. , vol.38 , Issue.12-13 , pp. 881-885
    • Romagnani, S.1
  • 73
    • 0028963908 scopus 로고
    • Constitutive and allergen-induced expression of eotaxin mRNA in the guinea pig lung
    • ROTHENBERG, M.E.; LUSTER, A.D.; LILLY, C.M.; DRAZEN, J.M.; LEDER, P. Constitutive and allergen-induced expression of eotaxin mRNA in the guinea pig lung. J Exp. Med., v.181, n.3, p.1211-1216, 1995.
    • (1995) J Exp. Med. , vol.181 , Issue.3 , pp. 1211-1216
    • Rothenberg, M.E.1    Luster, A.D.2    Lilly, C.M.3    Drazen, J.M.4    Leder, P.5
  • 75
    • 0034929204 scopus 로고    scopus 로고
    • The anti-inflammatory effects of leukotriene-modifying drugs and their use in asthma
    • SALVI, S.S.; KRISHNA, M.T.; SAMPSON, A.P.; HOLGATE, S.T. The anti-inflammatory effects of leukotriene-modifying drugs and their use in asthma. Chest, v.119, n.5, p.1533-1546, 2001.
    • (2001) Chest , vol.119 , Issue.5 , pp. 1533-1546
    • Salvi, S.S.1    Krishna, M.T.2    Sampson, A.P.3    Holgate, S.T.4
  • 76
    • 2942744546 scopus 로고    scopus 로고
    • Cardiovascular effects of beta agonists in patients with asthma and COPD: A meta-analysis
    • SALPETER, S.R.; ORMISTON, T.M.; SALPETER, E.E. Cardiovascular effects of beta agonists in patients with asthma and COPD: a meta-analysis. Chest, v.125, n.6, p.2309-2321, 2004.
    • (2004) Chest , vol.125 , Issue.6 , pp. 2309-2321
    • Salpeter, S.R.1    Ormiston, T.M.2    Salpeter, E.E.3
  • 77
    • 0021821768 scopus 로고
    • Identification of a lymphokine that stimulates eosinophil differentiation in vitro. Its relationship to interleukin 3, and functional properties of eosinophils produced in cultures
    • SANDERSON, C.J.; WARREN, D.J.; STRATH, M. Identification of a lymphokine that stimulates eosinophil differentiation in vitro. Its relationship to interleukin 3, and functional properties of eosinophils produced in cultures. J. Exp. Med., v.162, n.1, p.60-74, 1985.
    • (1985) J. Exp. Med. , vol.162 , Issue.1 , pp. 60-74
    • Sanderson, C.J.1    Warren, D.J.2    Strath, M.3
  • 78
    • 84889486721 scopus 로고    scopus 로고
    • a history. West Sussex: John Wiley and Sons
    • SNEADER, W. Drug discovery: a history. West Sussex: John Wiley and Sons, 2005. 472 p.
    • (2005) Drug discovery: , pp. 472
    • Sneader, W.1
  • 79
    • 0031747530 scopus 로고    scopus 로고
    • The role of ICAM-1 on T-cells in the pathogenesis of asthma
    • STANCIU, L.A.; DJUKANOVIC, R. The role of ICAM-1 on T-cells in the pathogenesis of asthma. Eur. Respir. J., v.11, n.4, p.949-957, 1998.
    • (1998) Eur. Respir. J. , vol.11 , Issue.4 , pp. 949-957
    • Stanciu, L.A.1    Djukanovic, R.2
  • 80
    • 0027216415 scopus 로고
    • Sudden-onset fatal asthma. A distinct entity with few eosinophils and relatively more neutrophils in the airway submucosa?
    • SUR, S.; CROTTY, T.B.; KEPHART, G.M.; HYMA, B.A.; COLBY, T.V.; REED, C.E.; HUNT, L.W.; GLEICH, G.J. Sudden-onset fatal asthma. A distinct entity with few eosinophils and relatively more neutrophils in the airway submucosa? Am. Rev. Respir. Dis., v.148, n.3, p.713-719, 1993.
    • (1993) Am. Rev. Respir. Dis. , vol.148 , Issue.3 , pp. 713-719
    • Sur, S.1    Crotty, T.B.2    Kephart, G.M.3    Hyma, B.A.4    Colby, T.V.5    Reed, C.E.6    Hunt, L.W.7    Gleich, G.J.8
  • 81
    • 12444297936 scopus 로고    scopus 로고
    • Inflammatory events in severe acute asthma
    • TILLIE-LEBLOND, I.; GOSSET, P.; TONNEL, A.B. Inflammatory events in severe acute asthma. Allergy, v.60, n.1, p.23-29, 2005.
    • (2005) Allergy , vol.60 , Issue.1 , pp. 23-29
    • Tillie-Leblond, I.1    Gosset, P.2    Tonnel, A.B.3
  • 82
    • 0032076563 scopus 로고    scopus 로고
    • Exploration of nature's chemodiversity: The role of secondary metabolites as leads in drug development
    • VERPOORTE, R. Exploration of nature's chemodiversity: the role of secondary metabolites as leads in drug development. Drug Discovery Today, v.3, n.5, p.232-238, 1999.
    • (1999) Drug Discovery Today , vol.3 , Issue.5 , pp. 232-238
    • Verpoorte, R.1
  • 84
    • 0035479909 scopus 로고    scopus 로고
    • Effects of Ginkgo biloba extract (EGb 761) and quercetin on lipopolysaccharide-induced signaling pathways involved in the release of tumor necrosis factor-α
    • WADSWORTH, T.L.; MCDONALD, T.L.; KOOP, D.R. Effects of Ginkgo biloba extract (EGb 761) and quercetin on lipopolysaccharide-induced signaling pathways involved in the release of tumor necrosis factor-α. Biochem. Pharmacol., v.62, n.7, p.963-974, 2001.
    • (2001) Biochem. Pharmacol. , vol.62 , Issue.7 , pp. 963-974
    • Wadsworth, T.L.1    McDonald, T.L.2    Koop, D.R.3
  • 85
    • 0034795649 scopus 로고    scopus 로고
    • Carbon dioxide is the major metabolite of quercetin in humans
    • WALLE, T.; WALLE, U.K.; HALUSHKA, P.V. Carbon dioxide is the major metabolite of quercetin in humans. J. Nutr., v.131, n.10, p.2648-2652, 2001.
    • (2001) J. Nutr. , vol.131 , Issue.10 , pp. 2648-2652
    • Walle, T.1    Walle, U.K.2    Halushka, P.V.3
  • 86
    • 0347510572 scopus 로고    scopus 로고
    • Lethal quercetin-digoxin interaction in pigs
    • WANG, Y.H.; CHAO, P.D.; HSIU, S.L.; WEN, K.C.; HOU, Y.C. Lethal quercetin-digoxin interaction in pigs. Life Sci., v.74, n.10, p.1191-1197, 2004.
    • (2004) Life Sci. , vol.74 , Issue.10 , pp. 1191-1197
    • Wang, Y.H.1    Chao, P.D.2    Hsiu, S.L.3    Wen, K.C.4    Hou, Y.C.5
  • 87
    • 33747756534 scopus 로고    scopus 로고
    • Asthma: Defining of the persistent adult phenotypes
    • WENZEL, S.E. Asthma: defining of the persistent adult phenotypes. Lancet, v.386, n.9537, p.804-813, 2006.
    • (2006) Lancet , vol.386 , Issue.9537 , pp. 804-813
    • Wenzel, S.E.1
  • 88
    • 0042527410 scopus 로고    scopus 로고
    • The management of acute severe asthma in adults
    • WORT, S.J. The management of acute severe asthma in adults. Current Anaesthesia & Critical Care, v.14, n.2, p.81-89, 2003.
    • (2003) Current Anaesthesia & Critical Care , vol.14 , Issue.2 , pp. 81-89
    • Wort, S.J.1
  • 89
    • 58149348758 scopus 로고    scopus 로고
    • Inhibition of quercetin on liver fibrosis due to Schistosoma japonicum infection and on the expression of immediate early gene and metalloproteinase 1 inhibitor in liver tissue of mice
    • XU, B.; HE, S.S.; HAN, C.R. Inhibition of quercetin on liver fibrosis due to Schistosoma japonicum infection and on the expression of immediate early gene and metalloproteinase 1 inhibitor in liver tissue of mice. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi, v.24, n.2, p.148-149, 2006.
    • (2006) Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi , vol.24 , Issue.2 , pp. 148-149
    • Xu, B.1    He, S.S.2    Han, C.R.3
  • 90
    • 0023875104 scopus 로고
    • Purified interleukin 5 supports the terminal differentiation and proliferation of murine eosinophilic precursors
    • YAMAGUCHI, Y.; SUDA, T.; SUDA J.; EGUCHI, M.; HARADA, N.; TOMINAGA, A.; TAKATSU, K. Purified interleukin 5 supports the terminal differentiation and proliferation of murine eosinophilic precursors. J. Exp. Med., v.167, n.1, p.43-56, 1988.
    • (1988) J. Exp. Med. , vol.167 , Issue.1 , pp. 43-56
    • Yamaguchi, Y.1    Suda, T.2    Suda, J.3    Eguchi, M.4    Harada, N.5    Tominaga, A.6    Takatsu, K.7
  • 91
    • 68149138453 scopus 로고    scopus 로고
    • Quercetin inhibits IL-1 beta-induced ICAM-1 expression in pulmonary epithelial cell line A549 through the MAPK pathways
    • YING, B.; YANG, T.; SONG, X.; HU, X.; FAN, H.; LU, X.; CHEN, L.; CHENG, D.; WANG, T.; LIU, D.; XU, D.; WEI, Y.; WEN, F. Quercetin inhibits IL-1 beta-induced ICAM-1 expression in pulmonary epithelial cell line A549 through the MAPK pathways. Mol. Biol. Rep., v.36, n.6, p.1825-1832, 2009.
    • (2009) Mol. Biol. Rep. , vol.36 , Issue.6 , pp. 1825-1832
    • Ying, B.1    Yang, T.2    Song, X.3    Hu, X.4    Fan, H.5    Lu, X.6    Chen, L.7    Cheng, D.8    Wang, T.9    Liu, D.10    Xu, D.11    Wei, Y.12    Wen, F.13
  • 92
    • 0037326942 scopus 로고    scopus 로고
    • Chemokines in asthma: Cooperative interaction between chemokines and IL-13
    • ZIMMERMANN, N.; HERSHEY, G.K.; FOSTER, P.S.; ROTHENBERG, M.E. Chemokines in asthma: cooperative interaction between chemokines and IL-13. J Allergy Clin. Immunol., v.111, n.2, p.227-242, 2003.
    • (2003) J Allergy Clin. Immunol. , vol.111 , Issue.2 , pp. 227-242
    • Zimmermann, N.1    Hershey, G.K.2    Foster, P.S.3    Rothenberg, M.E.4


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