IL-5 drives eosinophils from bone marrow to blood and tissues in a guinea-pig model of visceral larva migrans syndrome

Mediators of Inflammation

Volumn 5, Issue 1, 1996, Pages 24-31

  Faccioli, L H ^a   Mokwa, C A V F ^a   Silva, C L ^a   Rocha, G M ^a   Araujo, J I ^a   Nahori, M A ^b   Vargaftig, B B ^b  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b INSTITUT PASTEUR   (France)

Author keywords

Eosinophil; Eosinophilia by Toxocara canis; IL 5 in eosinophilia; Toxocara canis

Indexed keywords

INTERLEUKIN 5;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BONE MARROW; CONTROLLED STUDY; EOSINOPHIL; EOSINOPHILIA; FEMALE; GUINEA PIG; LUNG LAVAGE; NONHUMAN; PRIORITY JOURNAL; TOXOCARA CANIS; VISCERAL LARVA MIGRANS SYNDROME;

ANIMALIA; CANIS; CAVIA; CAVIA PORCELLUS; SUS SCROFA; TOXOCARA CANIS;

EID: 0029988623     PISSN: 09629351     EISSN: 14661861     Source Type: Journal    
DOI: 10.1155/S096293519600004X     Document Type: Article

References (27)

1. Nutman TB, Ottesen EA, Cohen SG. The eosinophil, eosinophilic and eosinophil-related disorders. Allergy Proc. 1989; 10: 47–62.
2. Glickman LT, Schantz PM. Epidemiology and pathogenesis of zoonotic toxocariasis. Epidem Rev. 1981; 3: 230–250.
3. Beaver P, Snyder H, Carrera G, Dent J, Lafferty J. Chronic eosinophilia due to visceral larva migrans. Pediatrics. 1952; 9: 7–19.
4. Limaye AP, Abrams JS, Silver JE, Ottesen EA, Nutman TB. Regulation of parasite-induced eosinophilia: selectively increased interleukin 5 produc tion in helminth-infected patients. J Exp Med. 1990; 172: 399–402.
5. Steel C, Nutman TB. Regulation of IL-5 in onchocerciasis: a critical role for IL-2. J Immunol. 1993; 150: 5511–5518.
6. Yamaguchi Y, Matsui T, Kasahara T, et al. In vivo changes of hemapoietic progenitors and the expression of the interleukin 5 gene in eosinophilic mice infected with Toxocara canis. Exp Hematol. 1990; 18: 1152–1157.
7. Parsons JC, Coffman RL, Grieve RB. Antibody to interleukin 5 prevents blood and tissue eosinophilia but not liver trapping in murine larval toxocariasis. Parasite Immunol. 1993; 15: 501–508.
8. Coffman RL, Seymour BWP, Hudak S, Jackson J, Rennick D. Antibody to interleukin-5 inhibits helminth-induced eosinophilia in mice. Science. 1989; 245: 308–310.
9. Sher A, Coffman RL, Hieny S, Cheever AW. Ablation of eosinophil and IgE responses with anti-IL-5 or anti-IL-4 antibodies fails to affect immunity against Schistosoma mansoni in the mouse. J Immunol. 1990; 145: 3911–3916.
10. Urban Jr JF, Katona IM, Paul WE, Finkelman FD. Interleukin 4 is impor tant in protective immunity to a gastrointestinal nematode infection in mice. Proc Natl Acad Sci USA. 1991; 88: 5513–5517.
11. Yamaguchi A, Suda T, Suda J, et al. Purified interleukin 5 (IL-5) supports the terminal differentiation and proliferation of murine eosinophilic precursors. J Exp Med. 1988; 167: 43–56.
12. Yamaguchi Y, Hayashi Y, Sugama Y, et al. Highly purified murine inter leukin 5 (IL-5) stimulates eosinophil function and prolongs in vitro survi val. IL-5 as an eosinophil chemotactic factor. J Exp Med. 1988; 167: 1737–1752.
13. Rothenberg ME, Petersen J, Stevens RL, Silberstein DS, McKenzie DT, Austen KF, Owen WF. IL-5-dependent conversion of normodense human eosinophils to the hypodense phenotype uses 3T3 fibroblasts for enhanced viability, accelerated hypodensity, and sustained antibody-dependent cytotoxicity. J Immunol. 1989; 143: 2311–2316.
14. Collins PD, Weg VB, Faccioli LH, Watson ML, Moqbel R, Williams TJ. Eosinophil accumulation induced by human interleukin-8 in the guinea pig in vivo. Immunology. 1993; 79: 312–318.
15. Sehmi R, Wardlavo AJ, Cromwell O, Kurihara K, Waltmann P, Kay AB. Interleukin-5 selectively enhances the chemotactic response of eosino phils obtained from normal but not eosinophilic subjects. Blood. 1992; 79: 2952–2959.
16. Moser R, Fehr J, Bruijnzeel PLB. IL-4 controls the selective endothelium-driven transmigration of eosinophils from allergic individuals. J Immunol. 1992; 149: 1432–1438.
17. Olson LJ, Schulz CW. Nematode induced hypersensitivity reactions in guinea pigs: onset of eosinophilia and positive Schultz-Dale reactions fol lowing graded infection with Toxocara canis. Ann N Y Acad Sci. 1963; 113: 440–455.
18. Kayes SG, Oaks JA. Development of the granulomatous response in murine toxocariasis. I. Initial events. Am J Pathol. 1978; 93: 277–294.
19. Basten A, Beeson PB. Mechanisms of eosinophilia. II. Role of the lymphocyte. J Exp Med. 1970; 131: 1288–1305.
20. Plaut M, Pierce JH, Watson CJ, Hanley-Hyde J, Nordan RP, Paul WE. Mast cell lines produce lymphokines in response to cross-linkage of Fc epsilon RI or to calcium ionophoras. Nature. 1989; 339: 64–67.
21. Sher A, Coffman RL, Hieny S, Scott P, Cheever AW. Interleukin 5 is required for the blood and tissue eosinophilia but not granuloma forma tion induced by infection with Schistosoma mansoni. Proc Natl Acad Sci USA. 1990; 87: 61–65.
22. Herndon FJ, Kayes SG. Depletion of eosinophils by anti-IL-5 monoclonal antibody treatment of mice infected with Trichinella spiralis does not alter parasite burden or immunologic resistance to reinfection. J Immunol. 1992; 149: 3642–3647.
23. Oshima T. Standardization of techniques for infecting mice with Tox ocara canis and observations on the normal migration routes of the larvae. J Parasitol. 1961; 47: 652.
24. Svetic A, Madden KB, Zhou XD, et al. A primary intestinal helminthic infection rapidly induces a gut-associated elevation of Th2-associated cytokines and IL-3. J Immunol. 1993; 150: 3434–3441.
25. Kusama Y, Takamoto M, Kasahara T, Takatsu K, Nariuchi H, Sugane K. Mechanisms of eosinophilia in BALB/c-nu/+ and congenitally athymic BALB/c-nu/nu mice infected with Toxocara canis. Immunology. 1995; 84: 461–168.
26. Rennick DM, Thompson-Snipes L, Coffman RL, Seymour BWP, Jackson JD, Hudak S. In vivo administration of antibody to interleukin-5 inhibits increased generation of eosinophils and their progenitors in bone marrow of parasitized mice. Blood. 1990; 76: 312–316.
27. Petrolani M, Ruffle C, Lapa e Silva JR, Joseph D, Lobb RR, Boris Vargaftig B. Antibody to very late activation antigen 4 prevents antigen-induced bronchial hyperreactivity and cellular infiltration in guinea pig airways. J Exp Med. 1994; 180: 795–805.