Induction of Apoptosis in Human Breast Cancer Cells via Caspase Pathway by Vernodalin Isolated from Centratherum anthelminticum (L.) Seeds

PLoS ONE

Volumn 8, Issue 2, 2013, Pages

  Looi, Chung Yeng ^a   Arya, Aditya ^a   Cheah, Foo Kit ^a   Muharram, Bushra ^a   Leong, Kok Hoong ^a   Mohamad, Khalit ^a   Wong, Won Fen ^a   Rai, Nitika ^b   Mustafa, Mohd Rais ^a  

^a UNIVERSITY OF MALAYA   (Malaysia)

^b Amritum Bio Botanica Herbs Research Laboratory Pvt Ltd   (India)

Author keywords

[No Author keywords available]

Indexed keywords

12,13 DIHYDROXYOLEIC ACID; ANTINEOPLASTIC AGENT; CASPASE; CASPASE 3; CASPASE 7; CASPASE 8; CASPASE 9; CENTRATHERUM ANTHELMINTICUM EXTRACT; CHLOROFORM; CYTOCHROME C; DOXORUBICIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PLANT EXTRACT; PROTEIN BCL 2; PROTEIN BCL XL; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; VERNODALIN;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; ASTERACEAE; BIOASSAY; BREAST CANCER; CANCER CELL CULTURE; CANCER GROWTH; CANCER INHIBITION; CELL SIZE; CENTRATHERUM ANTHELMINTICUM; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA FRAGMENTATION; DOWN REGULATION; DRUG CYTOTOXICITY; DRUG IDENTIFICATION; DRUG ISOLATION; DRUG STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; MASS SPECTROMETRY; MITOCHONDRIAL MEMBRANE POTENTIAL; NUCLEAR MAGNETIC RESONANCE; PLANT SEED; PROTEIN CLEAVAGE; PROTEIN SECRETION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BREAST NEOPLASMS; CASPASES; CELL CYCLE CHECKPOINTS; CELL PROLIFERATION; DNA FRAGMENTATION; FEMALE; HUMANS; MCF-7 CELLS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; PLANT EXTRACTS; REACTIVE OXYGEN SPECIES; SEEDS; SESQUITERPENES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84874280548     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0056643     Document Type: Article

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