메뉴 건너뛰기




Volumn 3, Issue AUG, 2012, Pages

Involvement of distinct PKC gene products in T cell functions

Author keywords

Immune disease therapy; PKC isotypes; Protein kinases; T cell regulation

Indexed keywords


EID: 84874215284     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2012.00220     Document Type: Article
Times cited : (32)

References (140)
  • 1
    • 0036956424 scopus 로고    scopus 로고
    • Protein kinase C-s: its unique structure and function
    • Akita, Y. (2002). Protein kinase C-s: its unique structure and function. J. Biochem. 132, 847-852.
    • (2002) J. Biochem. , vol.132 , pp. 847-852
    • Akita, Y.1
  • 2
    • 33746601071 scopus 로고    scopus 로고
    • Thyroid hormones increase inducible nitric oxide synthase gene expression downstream from PKCi; in murine tumor T lymphocytes
    • Barreiro Arcos, M. L., Gorelik, G., Klecha, A., Genaro, A. M., and Cremaschi, G. A. (2006). Thyroid hormones increase inducible nitric oxide synthase gene expression downstream from PKCi; in murine tumor T lymphocytes. Am. J. Physiol. Cell Physiol. 291, C327-C336.
    • (2006) Am. J. Physiol. Cell Physiol. , vol.291
    • Barreiro Arcos, M.L.1    Gorelik, G.2    Klecha, A.3    Genaro, A.M.4    Cremaschi, G.A.5
  • 3
    • 0035943657 scopus 로고    scopus 로고
    • Complex formation and cooperation of protein kinase C 9 and Akt1/protein kinase B a in the NF-K B transactivation cascade in Jurkat T cells
    • Bauer, B., Krumbock, N., Fresser, F., Hochholdinger, F., Spitaler, M., Simm, A., Uberall, F., Schraven, B., and Baier, G. (2001). Complex formation and cooperation of protein kinase C 9 and Akt1/protein kinase B a in the NF-K B transactivation cascade in Jurkat T cells. J. Biol. Chem. 276, 31627-31634.
    • (2001) J. Biol. Chem. , vol.276 , pp. 31627-31634
    • Bauer, B.1    Krumbock, N.2    Fresser, F.3    Hochholdinger, F.4    Spitaler, M.5    Simm, A.6    Uberall, F.7    Schraven, B.8    Baier, G.9
  • 4
    • 0034711239 scopus 로고    scopus 로고
    • Protein kinase C 9 and s promote T-cell survival by a rsk-dependent phosphorylation and inactivation of BAD
    • Bertolotto, C., Maulon, L., Filippa, N., Baier, G., and Auberger, P. (2000). Protein kinase C 9 and s promote T-cell survival by a rsk-dependent phosphorylation and inactivation of BAD. J. Biol. Chem. 275, 37246-37250.
    • (2000) J. Biol. Chem. , vol.275 , pp. 37246-37250
    • Bertolotto, C.1    Maulon, L.2    Filippa, N.3    Baier, G.4    Auberger, P.5
  • 5
  • 6
    • 12444347427 scopus 로고    scopus 로고
    • Inhibition of protein kinase CβII increases glucose uptake in 3T3-L1 adipocytes through elevated expression of glucose transporter 1 at the plasma membrane
    • Bosch, R. R., Bazuine, M., Wake, M. M., Span, P. N., Olthaar, A. J., Schurmann, A., Maassen, J. A., Hermus, A. R., Willems, P. H., and Sweep, C. G. (2003). Inhibition of protein kinase CβII increases glucose uptake in 3T3-L1 adipocytes through elevated expression of glucose transporter 1 at the plasma membrane. Mol. Endocrinol. 17, 1230-1239.
    • (2003) Mol. Endocrinol. , vol.17 , pp. 1230-1239
    • Bosch, R.R.1    Bazuine, M.2    Wake, M.M.3    Span, P.N.4    Olthaar, A.J.5    Schurmann, A.6    Maassen, J.A.7    Hermus, A.R.8    Willems, P.H.9    Sweep, C.G.10
  • 7
    • 0033636908 scopus 로고    scopus 로고
    • A PKC-eta/Fyn-dependent pathway leading to keratinocyte growth arrest and differentiation
    • Cabodi, S., Calautti, E., Talora, C., Kuroki, T., Stein, P. L., and Dotto, G. P. (2000). A PKC-eta/Fyn-dependent pathway leading to keratinocyte growth arrest and differentiation. Mol. Cell 6, 1121-1129.
    • (2000) Mol. Cell , vol.6 , pp. 1121-1129
    • Cabodi, S.1    Calautti, E.2    Talora, C.3    Kuroki, T.4    Stein, P.L.5    Dotto, G.P.6
  • 8
    • 0141756175 scopus 로고    scopus 로고
    • Integrin avidity regulation: are changes in affinity and conformation underemphasized
    • Carman, C. V., and Springer, T. A. (2003). Integrin avidity regulation: are changes in affinity and conformation underemphasized? Curr. Opin. Cell Biol. 15, 547-556.
    • (2003) Curr Opin. Cell Biol. , vol.15 , pp. 547-556
    • Carman, C.V.1    Springer, T.A.2
  • 9
    • 0034746792 scopus 로고    scopus 로고
    • Protein kinase Cepsilon is required for macrophage activation and defense against bacterial infection
    • Castrillo, A., Pennington, D. J., Otto, F., Parker, P. J., Owen, M. J., and Boscá, L. (2001). Protein kinase Cepsilon is required for macrophage activation and defense against bacterial infection.J. Exp. Med. 194, 1231-1242.
    • (2001) J. Exp. Med. , vol.194 , pp. 1231-1242
    • Castrillo, A.1    Pennington, D.J.2    Otto, F.3    Parker, P.J.4    Owen, M.J.5    Boscá, L.6
  • 10
    • 0035004512 scopus 로고    scopus 로고
    • PKCS inhibits anchorage-dependent and -independent growth, enhances differentiation, and increases apopto-sis in CaCo-2 cells
    • Cerda, S. R., Bissonnette, M., Scaglione-Sewell, B., Lyons, M. R., Khare, S., Mustafi, R., and Brasitus, T. A. (2001). PKCS inhibits anchorage-dependent and -independent growth, enhances differentiation, and increases apopto-sis in CaCo-2 cells. Gastroenterology 120, 1700-1712.
    • (2001) Gastroenterology , vol.120 , pp. 1700-1712
    • Cerda, S.R.1    Bissonnette, M.2    Scaglione-Sewell, B.3    Lyons, M.R.4    Khare, S.5    Mustafi, R.6    Brasitus, T.A.7
  • 11
    • 77957926529 scopus 로고    scopus 로고
    • Specific inhibition of protein kinase Cbeta expression by antisense RNA affects the activation of Jurkat T lymphoma cells
    • Cervino, M. C, Lopez-Lago, M. A., Vinuela, J. E., and Barja, P. (2010). Specific inhibition of protein kinase Cbeta expression by antisense RNA affects the activation of Jurkat T lymphoma cells. J. Biol. Regul. Homeost. Agents 24,273-285.
    • (2010) J. Biol. Regul. Homeost. Agents , vol.24 , pp. 273-285
    • Cervino, M.C.1    Lopez-Lago, M.A.2    Vinuela, J.E.3    Barja, P.4
  • 12
    • 0038520117 scopus 로고    scopus 로고
    • Disruption of protein kinase Ceta results in impairment of wound healing and enhancement of tumor formation in mouse skin carcinogenesis
    • Chida, K., Hara, T., Hirai, T., Konishi, C., Nakamura, K., Nakao, K., Aiba, A., Katsuki, M., and Kuroki, T. (2003). Disruption of protein kinase Ceta results in impairment of wound healing and enhancement of tumor formation in mouse skin carcinogenesis. Cancer Res. 63, 2404-2408.
    • (2003) Cancer Res , vol.63 , pp. 2404-2408
    • Chida, K.1    Hara, T.2    Hirai, T.3    Konishi, C.4    Nakamura, K.5    Nakao, K.6    Aiba, A.7    Katsuki, M.8    Kuroki, T.9
  • 13
    • 0031714290 scopus 로고    scopus 로고
    • Assignment of protein kinase C eta (Pkch) to mouse chromosome band 12C3-D2 by in situ hybridization
    • Chida, K., Nakada, T., Otsuka, H., Kuroki, T., and Satoh, H. (1998). Assignment of protein kinase C eta (Pkch) to mouse chromosome band 12C3-D2 by in situ hybridization. Cytogenet. Cell Genet. 82, 30-31.
    • (1998) Cytogenet. Cell Genet. , vol.82 , pp. 30-31
    • Chida, K.1    Nakada, T.2    Otsuka, H.3    Kuroki, T.4    Satoh, H.5
  • 16
    • 0042854695 scopus 로고    scopus 로고
    • Protein kinase Cβ1, a major regulator of TCR-CD28-activated signal transduction leading to IL-2 gene transcription and secretion
    • Dreikhausen, U. E., Gorf, K., Resch, K., and Szamel, M. (2003). Protein kinase Cβ1, a major regulator of TCR-CD28-activated signal transduction leading to IL-2 gene transcription and secretion. Int. Immunol 15, 1089-1098.
    • (2003) Int. Immunol , vol.15 , pp. 1089-1098
    • Dreikhausen, U.E.1    Gorf, K.2    Resch, K.3    Szamel, M.4
  • 18
    • 38949197102 scopus 로고    scopus 로고
    • T-cell activation through immunological synapses and kinapses
    • Dustin, M. L. (2008). T-cell activation through immunological synapses and kinapses. Immunol. Rev. 221, 77-89.
    • (2008) Immunol. Rev. , vol.221 , pp. 77-89
    • Dustin, M.L.1
  • 19
    • 4344691642 scopus 로고    scopus 로고
    • Membranes as messengers in T cell adhesion signaling
    • Dustin, M. L., Bivona, T. G., and Philips, M. R. (2004). Membranes as messengers in T cell adhesion signaling. Nat. Immunol. 5, 363-372.
    • (2004) Nat. Immunol. , vol.5 , pp. 363-372
    • Dustin, M.L.1    Bivona, T.G.2    Philips, M.R.3
  • 20
    • 0024443411 scopus 로고
    • T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1
    • Dustin, M. L., and Springer, T. A. (1989). T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1. Nature 341, 619-624.
    • (1989) Nature , vol.341 , pp. 619-624
    • Dustin, M.L.1    Springer, T.A.2
  • 21
    • 0034695627 scopus 로고    scopus 로고
    • Regulation of human involucrin promoter activity by novel protein kinase C isoforms
    • Efimova, T., and Eckert, R. L. (2000). Regulation of human involucrin promoter activity by novel protein kinase C isoforms. J. Biol. Chem. 275, 1601-1607.
    • (2000) J. Biol. Chem. , vol.275 , pp. 1601-1607
    • Efimova, T.1    Eckert, R.L.2
  • 23
    • 0035555195 scopus 로고    scopus 로고
    • Proteolysis-independent regulation of PI3K by Cbl-b-mediated ubiqui-tination in T cells
    • Fang, D., and Liu, Y. C. (2001). Proteolysis-independent regulation of PI3K by Cbl-b-mediated ubiqui-tination in T cells. Nat. Immunol. 2, 870-875.
    • (2001) Nat. Immunol. , vol.2 , pp. 870-875
    • Fang, D.1    Liu, Y.C.2
  • 26
    • 22144437706 scopus 로고    scopus 로고
    • Stimulus-induced phosphorylation of PKC 9 at the C-terminal hydrophobic-motif in human T lymphocytes
    • Freeley, M., Volkov, Y., Kelleher, D., and Long, A. (2005). Stimulus-induced phosphorylation of PKC 9 at the C-terminal hydrophobic-motif in human T lymphocytes. Biochem. Biophys. Res. Commun. 334, 619-630.
    • (2005) Biochem. Biophys. Res. Commun. , vol.334 , pp. 619-630
    • Freeley, M.1    Volkov, Y.2    Kelleher, D.3    Long, A.4
  • 30
    • 0028911139 scopus 로고
    • Analysis of the role of protein kinase C-a, -s, and -t, in T cell activation
    • Genot, E. M., Parker, P. J., and Cantrell, D. A. (1995). Analysis of the role of protein kinase C-a, -s, and -t, in T cell activation. J. Biol. Chem. 270, 9833-9839.
    • (1995) J. Biol. Chem. , vol.270 , pp. 9833-9839
    • Genot, E.M.1    Parker, P.J.2    Cantrell, D.A.3
  • 31
    • 0029811866 scopus 로고    scopus 로고
    • Association of phosphatidylinositol 3 kinase to protein kinase C during interleukin-2 stimulation
    • Gomez, J., Martinez, C., Garcia, A., and Rebollo, A. (1996). Association of phosphatidylinositol 3 kinase to protein kinase C<; during interleukin-2 stimulation. Eur. J. Immunol. 26, 1781-1787.
    • (1996) Eur. J. Immunol. , vol.26 , pp. 1781-1787
    • Gomez, J.1    Martinez, C.2    Garcia, A.3    Rebollo, A.4
  • 33
    • 38449104652 scopus 로고    scopus 로고
    • Impaired T cell protein kinase C § activation decreases ERK pathway signaling in idiopathic and hydralazine-induced lupus
    • Gorelik, G., Fang, J. Y, Wu, A., Sawalha, A. H., and Richardson, B. (2007). Impaired T cell protein kinase C § activation decreases ERK pathway signaling in idiopathic and hydralazine-induced lupus. J. Immunol. 179, 5553-5563.
    • (2007) J. Immunol. , vol.179 , pp. 5553-5563
    • Gorelik, G.1    Fang, J.Y.2    Wu, A.3    Sawalha, A.H.4    Richardson, B.5
  • 34
    • 0041845331 scopus 로고    scopus 로고
    • Protein kinase C s dependence of the recovery from down-regulation of S1P1 G protein-coupled receptors of T lymphocytes
    • Graeler, M. H., Kong, Y., Karliner, J. S., and Goetzl, E. J. (2003). Protein kinase C s dependence of the recovery from down-regulation of S1P1 G protein-coupled receptors of T lymphocytes. J. Biol. Chem. 278, 27737-27741.
    • (2003) J. Biol. Chem. , vol.278 , pp. 27737-27741
    • Graeler, M.H.1    Kong, Y.2    Karliner, J.S.3    Goetzl, E.J.4
  • 36
    • 34548249993 scopus 로고    scopus 로고
    • PKC9 cooperates with atypical PKCi; and PKCi in NF-KB tr ansactivation of T lymphocytes
    • Gruber, T., Fresser, F., Jenny, M., Uberall, F., Leitges, M., and Baier, G. (2008). PKC9 cooperates with atypical PKCi; and PKCi in NF-KB tr ansactivation of T lymphocytes. Mol. Immunol. 45, 117-126.
    • (2008) Mol. Immunol. , vol.45 , pp. 117-126
    • Gruber, T.1    Fresser, F.2    Jenny, M.3    Uberall, F.4    Leitges, M.5    Baier, G.6
  • 39
    • 77955013336 scopus 로고    scopus 로고
    • PKC9 is necessary for efficient activation of NFkB, NFAT,andAP-1 during positive selection of thymocytes
    • Gruber, T., Pfeifhofer-Obermair, C, and Baier, G. (2010). PKC9 is necessary for efficient activation of NFkB, NFAT,andAP-1 during positive selection of thymocytes. Immunol. Lett. 132, 6-11.
    • (2010) Immunol. Lett. , vol.132 , pp. 6-11
    • Gruber, T.1    Pfeifhofer-Obermair, C.2    Baier, G.3
  • 40
    • 80755132102 scopus 로고    scopus 로고
    • Regulation of TGFβ receptor trafficking and signaling by atypical protein kinase C
    • Gunaratne, A., Benchabane, H., and Di Guglielmo, G. M. (2012). Regulation of TGFβ receptor trafficking and signaling by atypical protein kinase C. Cell Signal. 24, 119-130.
    • (2012) Cell Signal , vol.24 , pp. 119-130
    • Gunaratne, A.1    Benchabane, H.2    Di Guglielmo, G.M.3
  • 41
    • 54349086262 scopus 로고    scopus 로고
    • Differential requirement of PKC9 in the development and function of natural regulatory T cells
    • Gupta, S., Manicassamy, S., Vasu, C., Kumar, A., Shang, W, and Sun, Z. (2008a). Differential requirement of PKC9 in the development and function of natural regulatory T cells. Mol. Immunol. 46, 213-224.
    • (2008) Mol. Immunol. , vol.46 , pp. 213-224
    • Gupta, S.1    Manicassamy, S.2    Vasu, C.3    Kumar, A.4    Shang, W.5    Sun, Z.6
  • 42
    • 42349114769 scopus 로고    scopus 로고
    • Mechanisms regulating the development and function of natural regulatory T cells
    • Gupta, S., Shang, W., and Sun, Z. (2008b). Mechanisms regulating the development and function of natural regulatory T cells. Arch. Immunol. Ther. Exp. (Warsz) 56, 85-102.
    • (2008) Arch. Immunol. Ther. Exp. (Warsz) , vol.56 , pp. 85-102
    • Gupta, S.1    Shang, W.2    Sun, Z.3
  • 43
    • 41149113441 scopus 로고    scopus 로고
    • The AKT-mTOR axis regulates de novo differentiation of CD4+Foxp3+ cells
    • Haxhinasto, S., Mathis, D., and Benoist, C. (2008). The AKT-mTOR axis regulates de novo differentiation of CD4+Foxp3+ cells. J. Exp. Med. 205, 565-574.
    • (2008) J. Exp. Med. , vol.205 , pp. 565-574
    • Haxhinasto, S.1    Mathis, D.2    Benoist, C.3
  • 46
    • 0037335629 scopus 로고    scopus 로고
    • Selective deficiency in protein kinase C isoenzyme expression and inadequacy in mitogen-activated protein kinase activation in cord blood T cells
    • Hii, C. S., Costabile, M., Mayne, G. C, Der, C. J., Murray, A. W, and Fer-rante, A. (2003). Selective deficiency in protein kinase C isoenzyme expression and inadequacy in mitogen-activated protein kinase activation in cord blood T cells. Biochem. J. 370, 497-503.
    • (2003) Biochem. J. , vol.370 , pp. 497-503
    • Hii, C.S.1    Costabile, M.2    Mayne, G.C.3    Der, C.J.4    Murray, A.W.5    Fer-rante, A.6
  • 47
    • 0642376906 scopus 로고    scopus 로고
    • Protein kinase Ci; (PKCi;): activation mechanisms and cellular functions
    • Hirai, T., and Chida, K. (2003). Protein kinase Ci; (PKCi;): activation mechanisms and cellular functions. J. Biochem. 133, 1-7.
    • (2003) J. Biochem. , vol.133 , pp. 1-7
    • Hirai, T.1    Chida, K.2
  • 48
    • 33845696273 scopus 로고    scopus 로고
    • BK-induced COX-2 expression via PKCS-dependent activation of p42/p44 MAPK and NFKB in astrocytes
    • Hsieh, H. L., Wang, H. H., Wu, C. Y, Jou, M. J., Yen, M. H., Parker, P., and Yang, C. M. (2007). BK-induced COX-2 expression via PKCS-dependent activation of p42/p44 MAPK and NFKB in astrocytes. Cell Signal. 19, 330-340.
    • (2007) Cell Signal , vol.19 , pp. 330-340
    • Hsieh, H.L.1    Wang, H.H.2    Wu, C.Y.3    Jou, M.J.4    Yen, M.H.5    Parker, P.6    Yang, C.M.7
  • 50
    • 0026742603 scopus 로고
    • Accelerated proliferation and interleukin-2 production of thymocytes by stimulation of soluble anti-CD3 monoclonal antibody in transgenic mice carrying a rabbit protein kinase C a
    • Iwamoto, T., Hagiwara, M., Hidaka, H., Isomura, T., Kioussis, D., and Nakashima, I. (1992). Accelerated proliferation and interleukin-2 production of thymocytes by stimulation of soluble anti-CD3 monoclonal antibody in transgenic mice carrying a rabbit protein kinase C a. J. Biol. Chem. 267,18644-18648.
    • (1992) J. Biol. Chem. , vol.267 , pp. 18644-18648
    • Iwamoto, T.1    Hagiwara, M.2    Hidaka, H.3    Isomura, T.4    Kioussis, D.5    Nakashima, I.6
  • 53
    • 0034658320 scopus 로고    scopus 로고
    • Protein kinase B regulates T lymphocyte survival, nuclear factor KB activation, and Bcl-X(L) levels in vivo
    • Jones, R. G., Parsons, M., Bonnard, M., Chan, V. S., Yeh, W C, Woodgett, J. R., and Ohashi, P. S. (2000). Protein kinase B regulates T lymphocyte survival, nuclear factor KB activation, and Bcl-X(L) levels in vivo. J. Exp. Med. 191,1721-1734.
    • (2000) J. Exp. Med. , vol.191 , pp. 1721-1734
    • Jones, R.G.1    Parsons, M.2    Bonnard, M.3    Chan, V.S.4    Yeh, W.C.5    Woodgett, J.R.6    Ohashi, P.S.7
  • 55
    • 0034649479 scopus 로고    scopus 로고
    • PKCeta associates with cyclin E/cdk2/p21 complex, phos-phorylates p21 and inhibits cdk2 kinase in keratinocytes
    • Kashiwagi, M., Ohba, M., Watan-abe, H., Ishino, K., Kasahara, K., Sanai, Y., Taya, Y., and Kuroki, T. (2000). PKCeta associates with cyclin E/cdk2/p21 complex, phos-phorylates p21 and inhibits cdk2 kinase in keratinocytes. Oncogene 19, 6334-6341.
    • (2000) Oncogene , vol.19 , pp. 6334-6341
    • Kashiwagi, M.1    Ohba, M.2    Watan-abe, H.3    Ishino, K.4    Kasahara, K.5    Sanai, Y.6    Taya, Y.7    Kuroki, T.8
  • 56
    • 0036146452 scopus 로고    scopus 로고
    • Rap1 functions as a key regulator of T-cell and antigen-presenting cell interactions and modulates T-cell responses
    • Katagiri, K., Hattori, M., Minato, N., and Kinashi, T. (2002). Rap1 functions as a key regulator of T-cell and antigen-presenting cell interactions and modulates T-cell responses. Mol. Cell Biol. 22, 1001-1015.
    • (2002) Mol. Cell Biol. , vol.22 , pp. 1001-1015
    • Katagiri, K.1    Hattori, M.2    Minato, N.3    Kinashi, T.4
  • 57
    • 0030768585 scopus 로고    scopus 로고
    • Subcellular localization and translocation of protein kinase C isoforms <; and s in human peripheral blood lymphocytes
    • Keenan, C, Volkov, Y, Kelleher, D., and Long, A. (1997). Subcellular localization and translocation of protein kinase C isoforms <; and s in human peripheral blood lymphocytes. Int. Immunol 9,1431-1439.
    • (1997) Int. Immunol , vol.9 , pp. 1431-1439
    • Keenan, C.1    Volkov, Y.2    Kelleher, D.3    Long, A.4
  • 58
    • 0036947279 scopus 로고    scopus 로고
    • Protein kinase C S (PKC S): activation mechanisms and functions
    • Kikkawa, U., Matsuzaki, H., and Yamamoto, T. (2002). Protein kinase C S (PKC S): activation mechanisms and functions.J. Biochem. 132, 831-839.
    • (2002) J. Biochem. , vol.132 , pp. 831-839
    • Kikkawa, U.1    Matsuzaki, H.2    Yamamoto, T.3
  • 59
    • 0027430234 scopus 로고
    • Differentiation-associated localization of nPKC eta, a Ca(++)-independent protein kinase C, in normal human skin and skin diseases
    • Koizumi, H., Kohno, Y., Osada, S., Ohno, S., Ohkawara, A., and Kuroki, T. (1993). Differentiation-associated localization of nPKC eta, a Ca(++)-independent protein kinase C, in normal human skin and skin diseases. J. Invest Dermatol 101, 858-863.
    • (1993) J. Invest Dermatol , vol.101 , pp. 858-863
    • Koizumi, H.1    Kohno, Y.2    Osada, S.3    Ohno, S.4    Ohkawara, A.5    Kuroki, T.6
  • 60
    • 80054895503 scopus 로고    scopus 로고
    • A motif in the V3 domain of the kinase PKC9 determines its localization in the immunological synapse and functions in T cells via association with CD28
    • Kong, K. F., Yokosuka, T., Canonigo-Balancio, A. J., Isakov, N., Saito, T., and Altman, A. (2011). A motif in the V3 domain of the kinase PKC9 determines its localization in the immunological synapse and functions in T cells via association with CD28. Nat. Immunol 12, 1105-1112.
    • (2011) Nat. Immunol , vol.12 , pp. 1105-1112
    • Kong, K.F.1    Yokosuka, T.2    Canonigo-Balancio, A.J.3    Isakov, N.4    Saito, T.5    Altman, A.6
  • 61
    • 0036314804 scopus 로고    scopus 로고
    • Association of protein kinase C with GABA(A) receptors containing alpha1 and alpha4 sub-units in the cerebral cortex: selective effects of chronic ethanol consumption
    • Kumar, S., Sieghart, W., and Morrow, A. L. (2002). Association of protein kinase C with GABA(A) receptors containing alpha1 and alpha4 sub-units in the cerebral cortex: selective effects of chronic ethanol consumption.J. Neurochem. 82, 110-117.
    • (2002) J. Neurochem. , vol.82 , pp. 110-117
    • Kumar, S.1    Sieghart, W.2    Morrow, A.L.3
  • 62
    • 84862622067 scopus 로고    scopus 로고
    • Protein kinase C-9 promotes Th17 differentiation via upregulation of Stat3
    • Kwon, M. J., Ma, J., Ding, Y, Wang, R., and Sun, Z. (2012). Protein kinase C-9 promotes Th17 differentiation via upregulation of Stat3. J. Immunol 188, 5887-5897.
    • (2012) J. Immunol , vol.188 , pp. 5887-5897
    • Kwon, M.J.1    Ma, J.2    Ding, Y.3    Wang, R.4    Sun, Z.5
  • 64
    • 15944410614 scopus 로고    scopus 로고
    • PDK1 nucleates T cell receptor-induced signaling complex for NF-KB activation
    • Lee, K. Y., D'Acquisto, F., Hayden, M. S., Shim, J. H., and Ghosh, S. (2005). PDK1 nucleates T cell receptor-induced signaling complex for NF-KB activation. Science 308, 114-118.
    • (2005) Science , vol.308 , pp. 114-118
    • Lee, K.Y.1    D'Acquisto, F.2    Hayden, M.S.3    Shim, J.H.4    Ghosh, S.5
  • 66
    • 21644447437 scopus 로고    scopus 로고
    • Protein kinase C <; associates with death inducing signaling complex and regulates Fas ligand-induced apoptosis
    • Leroy, I., De Thonel, A., Laurent, G., and Quillet-Mary, A. (2005). Protein kinase C <; associates with death inducing signaling complex and regulates Fas ligand-induced apoptosis. CellSignal 17, 1149-1157.
    • (2005) Cell Signal , vol.17 , pp. 1149-1157
    • Leroy, I.1    De Thonel, A.2    Laurent, G.3    Quillet-Mary, A.4
  • 68
    • 0033233483 scopus 로고    scopus 로고
    • Protein kinase CS targets mitochondria, alters mitochondrial membrane potential, and induces apoptosis in normal and neoplastic keratinocytes when overexpressed by an adenoviral vector
    • Li, L., Lorenzo, P. S., Bogi, K., Blum-berg, P. M., and Yuspa, S. H. (1999). Protein kinase CS targets mitochondria, alters mitochondrial membrane potential, and induces apoptosis in normal and neoplastic keratinocytes when overexpressed by an adenoviral vector. Mol. Cell. Biol. 19, 8547-8558.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 8547-8558
    • Li, L.1    Lorenzo, P.S.2    Bogi, K.3    Blum-berg, P.M.4    Yuspa, S.H.5
  • 69
    • 0037081849 scopus 로고    scopus 로고
    • Phosphorylation of the protein kinase C-9 activation loop and hydrophobic motif regulates its kinase activity, but only activation loop phosphorylation is critical to in vivo nuclear-factor-KB induction
    • Liu, Y, Graham, C., Li, A., Fisher, R. J., and Shaw, S. (2002). Phosphorylation of the protein kinase C-9 activation loop and hydrophobic motif regulates its kinase activity, but only activation loop phosphorylation is critical to in vivo nuclear-factor-KB induction. Biochem. J. 361, 255-265.
    • (2002) Biochem. J. , vol.361 , pp. 255-265
    • Liu, Y.1    Graham, C.2    Li, A.3    Fisher, R.J.4    Shaw, S.5
  • 70
    • 0034602963 scopus 로고    scopus 로고
    • Regulation of protein kinase C9 function during T cell activation by Lck-mediated tyrosine phosphorylation
    • Liu, Y, Witte, S., Liu, Y C., Doyle, M., Elly, C., and Altman, A. (2000). Regulation of protein kinase C9 function during T cell activation by Lck-mediated tyrosine phosphorylation. J. Biol. Chem. 275, 3603-3609.
    • (2000) J. Biol. Chem. , vol.275 , pp. 3603-3609
    • Liu, Y.1    Witte, S.2    Liu, Y.C.3    Doyle, M.4    Elly, C.5    Altman, A.6
  • 71
    • 47749150635 scopus 로고    scopus 로고
    • Phosphorylation of protein kinase CS on distinct tyrosine residues induces sustained activation of Erk1/2 via down-regulation of MKP-1: role in the apoptotic effect of etoposide
    • Lomonaco, S. L., Kahana, S., Blass, M., Brody, Y., Okhrimenko, H., Xiang, C., Finniss, S., Blumberg, P. M., Lee, H. K., and Brodie, C. (2008). Phosphorylation of protein kinase CS on distinct tyrosine residues induces sustained activation of Erk1/2 via down-regulation of MKP-1: role in the apoptotic effect of etoposide. J. Biol. Chem. 283, 17731-17739.
    • (2008) J. Biol. Chem. , vol.283 , pp. 17731-17739
    • Lomonaco, S.L.1    Kahana, S.2    Blass, M.3    Brody, Y.4    Okhrimenko, H.5    Xiang, C.6    Finniss, S.7    Blumberg, P.M.8    Lee, H.K.9    Brodie, C.10
  • 72
    • 0035879345 scopus 로고    scopus 로고
    • Cutting edge: protein kinase C β expression is critical for export of Il-2 from T cells
    • Long, A., Kelleher, D., Lynch, S., and Volkov, Y (2001). Cutting edge: protein kinase C β expression is critical for export of Il-2 from T cells. J. Immunol. 167,636-640.
    • (2001) J. Immunol. , vol.167 , pp. 636-640
    • Long, A.1    Kelleher, D.2    Lynch, S.3    Volkov, Y.4
  • 76
    • 84862072065 scopus 로고    scopus 로고
    • Protein kinase C-9 inhibits inducible regulatory T cell differentiation via an AKT-Foxo1/3a-dependent pathway
    • Ma, J., Ding, Y, Fang, X., Wang, R., and Sun, Z. (2012). Protein kinase C-9 inhibits inducible regulatory T cell differentiation via an AKT-Foxo1/3a-dependent pathway. J. Immunol. 188, 5337-5347.
    • (2012) J. Immunol. , vol.188 , pp. 5337-5347
    • Ma, J.1    Ding, Y.2    Fang, X.3    Wang, R.4    Sun, Z.5
  • 77
    • 58149300245 scopus 로고    scopus 로고
    • Protein kinase C S localizes to secretory lysosomes in CD8+ CTL and directly mediates TCR signals leading to granule exocytosis-mediated cytotoxicity
    • Ma, J. S., Haydar, T. F., and Radoja, S. (2008). Protein kinase C S localizes to secretory lysosomes in CD8+ CTL and directly mediates TCR signals leading to granule exocytosis-mediated cytotoxicity. J. Immunol. 181, 4716-4722.
    • (2008) J. Immunol. , vol.181 , pp. 4716-4722
    • Ma, J.S.1    Haydar, T.F.2    Radoja, S.3
  • 80
    • 3242790172 scopus 로고    scopus 로고
    • Protein kinase C 9 is critical for the development of in vivo T helper (Th)2 cell but not Th1 cell responses
    • Marsland, B. J., Soos, T. J., Spath, G., Littman, D. R., and Kopf, M. (2004). Protein kinase C 9 is critical for the development of in vivo T helper (Th)2 cell but not Th1 cell responses. J. Exp. Med. 200, 181-189.
    • (2004) J. Exp. Med. , vol.200 , pp. 181-189
    • Marsland, B.J.1    Soos, T.J.2    Spath, G.3    Littman, D.R.4    Kopf, M.5
  • 81
    • 0035844233 scopus 로고    scopus 로고
    • Regulation of nuclear factor K B transactivation. Implication of phosphatidylinositol 3-kinase and protein kinase C ́ in c-Rel activation by tumor necrosis factor a
    • Martin, A. G., San-Antonio, B., and Fresno, M. (2001). Regulation of nuclear factor K B transactivation. Implication of phosphatidylinositol 3-kinase and protein kinase C ́ in c-Rel activation by tumor necrosis factor a. J. Biol. Chem. 276, 15840-15849.
    • (2001) J. Biol. Chem. , vol.276 , pp. 15840-15849
    • Martin, A.G.1    San-Antonio, B.2    Fresno, M.3
  • 84
    • 0023684257 scopus 로고
    • The role of lymphocyte function-associated antigen 1 (LFA-1) in the adherence of T lymphocytes to B lymphocytes
    • Mazerolles, F., Lumbroso, C, Lecomte, O., Le Deist, F., and Fischer, A. (1988). The role of lymphocyte function-associated antigen 1 (LFA-1) in the adherence of T lymphocytes to B lymphocytes. Eur. J. Immunol. 18, 1229-1234.
    • (1988) Eur. J. Immunol. , vol.18 , pp. 1229-1234
    • Mazerolles, F.1    Lumbroso, C.2    Lecomte, O.3    Le Deist, F.4    Fischer, A.5
  • 87
    • 80555154815 scopus 로고    scopus 로고
    • Protein kinase Cs regulates proliferation and cell sensitivity to TGF-1β of CD4+ T lymphocytes: implications for Hashimoto thyroiditis
    • Mirandola, P., Gobbi, G., Masselli, E., Micheloni, C, Di Marcanto-nio, D., Queirolo, V, Chiodera, P., Meschi, T., and Vitale, M. (2011). Protein kinase Cs regulates proliferation and cell sensitivity to TGF-1β of CD4+ T lymphocytes: implications for Hashimoto thyroiditis. J. Immunol. 187,4721-4732.
    • (2011) J. Immunol. , vol.187 , pp. 4721-4732
    • Mirandola, P.1    Gobbi, G.2    Masselli, E.3    Micheloni, C.4    Di Marcanto-nio, D.5    Queirolo, V.6    Chiodera, P.7    Meschi, T.8    Vitale, M.9
  • 88
    • 0025751626 scopus 로고
    • Expression of protein kinase C genes in hemopoietic cells is cell-type- and B cell-differentiation stage specific
    • Mischak, H., Kolch, W, Goodnight, J., Davidson, W F., Rapp, U., Rose-John, S., and Mushinski, J. F. (1991). Expression of protein kinase C genes in hemopoietic cells is cell-type- and B cell-differentiation stage specific. J. Immunol. 147,3981-3987.
    • (1991) J. Immunol. , vol.147 , pp. 3981-3987
    • Mischak, H.1    Kolch, W.2    Goodnight, J.3    Davidson, W.F.4    Rapp, U.5    Rose-John, S.6    Mushinski, J.F.7
  • 90
    • 58149300250 scopus 로고    scopus 로고
    • Protein kinase C-9 is required for efficient positive selection
    • Morley, S. C, Weber, K. S., Kao, H., and Allen, P. M. (2008). Protein kinase C-9 is required for efficient positive selection. J. Immunol. 181, 4696-4708.
    • (2008) J. Immunol. , vol.181 , pp. 4696-4708
    • Morley, S.C.1    Weber, K.S.2    Kao, H.3    Allen, P.M.4
  • 91
    • 0032778043 scopus 로고    scopus 로고
    • Pro-B-cell-specific transcription and proapoptotic function of protein kinase Ceta
    • Morrow, T. A., Muljo, S. A., Zhang, J., Hardwick, J. M., and Schlissel, M. S. (1999). Pro-B-cell-specific transcription and proapoptotic function of protein kinase Ceta. Mol. Cell. Biol. 19, 5608-5618.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 5608-5618
    • Morrow, T.A.1    Muljo, S.A.2    Zhang, J.3    Hardwick, J.M.4    Schlissel, M.S.5
  • 92
    • 26644461205 scopus 로고    scopus 로고
    • Phorbol ester-induced G1 phase arrest selectively mediated by protein kinase CS-dependent induction of p21
    • Nakagawa, M., Oliva, J. L., Kothapalli, D., Fournier, A., Assoian, R. K., and Kazanietz, M. G. (2005). Phorbol ester-induced G1 phase arrest selectively mediated by protein kinase CS-dependent induction of p21. J. Biol. Chem. 280, 33926-33934.
    • (2005) J. Biol. Chem. , vol.280 , pp. 33926-33934
    • Nakagawa, M.1    Oliva, J.L.2    Kothapalli, D.3    Fournier, A.4    Assoian, R.K.5    Kazanietz, M.G.6
  • 93
    • 0036911112 scopus 로고    scopus 로고
    • c-Cbl and Cbl-b regulate T cell responsiveness by promoting ligand-induced TCR down-modulation
    • Naramura, M., Jang, I. K., Kole, H., Huang, F., Haines, D., and Gu, H. (2002). c-Cbl and Cbl-b regulate T cell responsiveness by promoting ligand-induced TCR down-modulation. Nat. Immunol. 3, 1192-1199.
    • (2002) Nat. Immunol. , vol.3 , pp. 1192-1199
    • Naramura, M.1    Jang, I.K.2    Kole, H.3    Huang, F.4    Haines, D.5    Gu, H.6
  • 94
    • 0034161386 scopus 로고    scopus 로고
    • Inhibition of degranulation and interleukin-6 production in mast cells derived from mice deficient in protein kinase Cbeta. Blood 95
    • Nechushtan, H., Leitges, M., Cohen, C, Kay, G., and Razin, E. (2000). Inhibition of degranulation and interleukin-6 production in mast cells derived from mice deficient in protein kinase Cbeta. Blood 95,1752- 1757.
    • (2000) , pp. 1752-1757
    • Nechushtan, H.1    Leitges, M.2    Cohen, C.3    Kay, G.4    Razin, E.5
  • 95
  • 96
    • 9344248995 scopus 로고    scopus 로고
    • Der f 2 activates phos-pholipase D in human T lymphocytes from Dermatophagoides farinae specific allergic individuals: involvement of protein kinase C-a
    • Oh, J. W., Kim, E. Y., Koo, B. S., Lee, H. B., Lee, K. S., Kim, Y. S., and Han, J. S. (2004). Der f 2 activates phos-pholipase D in human T lymphocytes from Dermatophagoides farinae specific allergic individuals: involvement of protein kinase C-a. Exp. Mol. Med. 36,486-492.
    • (2004) Exp. Mol. Med. , vol.36 , pp. 486-492
    • Oh, J.W.1    Kim, E.Y.2    Koo, B.S.3    Lee, H.B.4    Lee, K.S.5    Kim, Y.S.6    Han, J.S.7
  • 97
    • 0025687388 scopus 로고
    • A phorbol ester receptor/protein kinase, nPKC eta, a new member of the protein kinase C family predominantly expressed in lung and skin
    • Osada, S., Mizuno, K., Saido, T. C., Akita, Y, Suzuki, K., Kuroki, T., and Ohno, S. (1990). A phorbol ester receptor/protein kinase, nPKC eta, a new member of the protein kinase C family predominantly expressed in lung and skin. J. Biol. Chem. 265, 22434-22440.
    • (1990) J. Biol. Chem. , vol.265 , pp. 22434-22440
    • Osada, S.1    Mizuno, K.2    Saido, T.C.3    Akita, Y.4    Suzuki, K.5    Kuroki, T.6    Ohno, S.7
  • 98
    • 0033534525 scopus 로고    scopus 로고
    • The actin cytoskeleton and lymphocyte activation
    • Penninger, J. M., and Crabtree, G. R. (1999). The actin cytoskeleton and lymphocyte activation. Cell 96, 9-12.
    • (1999) Cell , vol.96 , pp. 9-12
    • Penninger, J.M.1    Crabtree, G.R.2
  • 101
    • 0038620475 scopus 로고    scopus 로고
    • Protein kinase C 9 affects Ca2+ mobilization and NFAT cell activation in primary mouse T cells
    • Pfeifhofer, C., Kofler, K., Gruber, T., Tabrizi, N. G., Lutz, C., Maly, K., Leitges, M., and Baier, G. (2003). Protein kinase C 9 affects Ca2+ mobilization and NFAT cell activation in primary mouse T cells. J. Exp. Med. 197,1525-1535.
    • (2003) J. Exp. Med. , vol.197 , pp. 1525-1535
    • Pfeifhofer, C.1    Kofler, K.2    Gruber, T.3    Tabrizi, N.G.4    Lutz, C.5    Maly, K.6    Leitges, M.7    Baier, G.8
  • 102
    • 0033214089 scopus 로고    scopus 로고
    • Cloning and characterization of the human protein kinase C-eta promoter
    • Quan, T., and Fisher, G. J. (1999). Cloning and characterization of the human protein kinase C-eta promoter. J. Biol. Chem. 274, 28566-28574.
    • (1999) J. Biol. Chem. , vol.274 , pp. 28566-28574
    • Quan, T.1    Fisher, G.J.2
  • 103
    • 79959376445 scopus 로고    scopus 로고
    • A cascade of protein kinase C isozymes promotes cytoskeletal polarization in T cells
    • Quann, E. J., Liu, X., Altan-Bonnet, G., and Huse, M. (2011). A cascade of protein kinase C isozymes promotes cytoskeletal polarization in T cells. Nat. Immunol. 12, 647-654.
    • (2011) Nat. Immunol. , vol.12 , pp. 647-654
    • Quann, E.J.1    Liu, X.2    Altan-Bonnet, G.3    Huse, M.4
  • 104
    • 0032973249 scopus 로고    scopus 로고
    • Inter action between B. 7 and CD28 costimulatory molecules is essential for the activation of effector function mediating spontaneous tumour regression
    • Rao, K. L., Varalakshmi, C, Kumari, A L., and Khar, A. (1999). Inter action between B.7 and CD28 costimulatory molecules is essential for the activation of effector function mediating spontaneous tumour regression. Scand. J. Immunol. 49,633-640.
    • (1999) Scand. J. Immunol. , vol.49 , pp. 633-640
    • Rao, K.L.1    Varalakshmi, C.2    Kumari, A.L.3    Khar, A.4
  • 105
    • 38449108120 scopus 로고    scopus 로고
    • Cutting edge: atypical PKCs regulate T lymphocyte polarity and scanning behavior
    • Real, E., Faure, S., Donnadieu, E., and Delon, J. (2007). Cutting edge: atypical PKCs regulate T lymphocyte polarity and scanning behavior. J. Immunol. 179, 5649-5652.
    • (2007) J. Immunol. , vol.179 , pp. 5649-5652
    • Real, E.1    Faure, S.2    Donnadieu, E.3    Delon, J.4
  • 106
    • 43949105866 scopus 로고    scopus 로고
    • Regulatory T cells and immune tolerance
    • Sakaguchi, S., Yamaguchi, T., Nomura, T.,and Ono, M. (2008). Regulatory T cells and immune tolerance. Cell 133, 775-787.
    • (2008) Cell , vol.133 , pp. 775-787
    • Sakaguchi, S.1    Yamaguchi, T.2    Nomura, T.3    Ono, M.4
  • 108
    • 8444243253 scopus 로고    scopus 로고
    • Differential regulation of Th2 and Th1 lung inflammatory responses by protein kinase C 9
    • Salek-Ardakani, S., So, T., Halteman, B. S., Altman, A., and Croft, M. (2004). Differential regulation of Th2 and Th1 lung inflammatory responses by protein kinase C 9. J. Immunol. 173, 6440-6447.
    • (2004) J. Immunol. , vol.173 , pp. 6440-6447
    • Salek-Ardakani, S.1    So, T.2    Halteman, B.S.3    Altman, A.4    Croft, M.5
  • 109
    • 28244464872 scopus 로고    scopus 로고
    • Protein kinase C9 controls The cells in experimental autoimmune encephalomyelitis
    • Salek-Ardakani, S., So, T., Halteman, B S., Altman, A., and Croft, M. (2005). Protein kinase C9 controls The cells in experimental autoimmune encephalomyelitis. J. Immunol. 175, 7635-7641.
    • (2005) J. Immunol. , vol.175 , pp. 7635-7641
    • Salek-Ardakani, S.1    So, T.2    Halteman, B.S.3    Altman, A.4    Croft, M.5
  • 110
    • 0037178289 scopus 로고    scopus 로고
    • Protein kinase C; phosphorylates nuclear factor of activated T cells and regulates its trans-activating activity
    • San-Antonio, B., Iniguez, M. A., and Fresno, M. (2002). Protein kinase C; phosphorylates nuclear factor of activated T cells and regulates its trans-activating activity. J. Biol. Chem. 277, 27073-27080.
    • (2002) J. Biol. Chem. , vol.277 , pp. 27073-27080
    • San-Antonio, B.1    Iniguez, M.A.2    Fresno, M.3
  • 111
    • 33846233038 scopus 로고    scopus 로고
    • Differential regulation of p65 and c-Rel NF-KB trans-activating activity by Cot. protein kinase C <; and NIK protein kinases in CD3/CD28 activated T cells
    • Sanchez-Valdepenas, C, Punzon, C, San-Antonio, B., Martin, A. G., and Fresno, M. (2007). Differential regulation of p65 and c-Rel NF-KB trans-activating activity by Cot, protein kinase C <; and NIK protein kinases in CD3/CD28 activated T cells. Cell Signal. 19,528-537.
    • (2007) Cell Signal. , vol.19 , pp. 528-537
    • Sanchez-Valdepenas, C.1    Punzon, C.2    San-Antonio, B.3    Martin, A.G.4    Fresno, M.5
  • 112
    • 25444490131 scopus 로고    scopus 로고
    • Protein kinase C § stimulates apoptosis by initiating G1 phase cell cycle progression and S phase arrest
    • Santiago-Walker, A. E., Fikaris, A. J., Kao, G. D., Brown, E. J., Kazani-etz, M. G., and Meinkoth, J. L. (2005). Protein kinase C § stimulates apoptosis by initiating G1 phase cell cycle progression and S phase arrest. J. Biol. Chem. 280, 32107-32114.
    • (2005) J. Biol. Chem. , vol.280 , pp. 32107-32114
    • Santiago-Walker, A.E.1    Fikaris, A.J.2    Kao, G.D.3    Brown, E.J.4    Kazani-etz, M.G.5    Meinkoth, J.L.6
  • 115
    • 0742270964 scopus 로고    scopus 로고
    • Complex and dynamic redistribution of NF-KB signaling intermediates in response to T cell receptor stimulation
    • Schaefer, B. C, Kappler, J. W., Kupfer, A., and Marrack, P. (2004). Complex and dynamic redistribution of NF-KB signaling intermediates in response to T cell receptor stimulation. Proc. Natl. Acad. Sci. U.S.A. 101, 1004-1009.
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 1004-1009
    • Schaefer, B.C.1    Kappler, J.W.2    Kupfer, A.3    Marrack, P.4
  • 116
    • 0032802771 scopus 로고    scopus 로고
    • Inhibition of T cell apoptosis by IFN-β rapidly reverses nuclear translocation of protein kinase C-S
    • Scheel-Toellner, D., Pilling, D., Akbar, A. N., Hardie, D., Lombardi, G., Salmon, M., and Lord, J. M. (1999). Inhibition of T cell apoptosis by IFN-β rapidly reverses nuclear translocation of protein kinase C-S. Eur. J. Immunol. 29, 2603-2612.
    • (1999) Eur. J. Immunol. , vol.29 , pp. 2603-2612
    • Scheel-Toellner, D.1    Pilling, D.2    Akbar, A.N.3    Hardie, D.4    Lombardi, G.5    Salmon, M.6    Lord, J.M.7
  • 117
    • 65549136983 scopus 로고    scopus 로고
    • Mechanisms of foxp3+ T regulatory cell-mediated suppression
    • Shevach, E. M. (2009). Mechanisms of foxp3+ T regulatory cell-mediated suppression. Immunity 30, 636-645.
    • (2009) Immunity , vol.30 , pp. 636-645
    • Shevach, E.M.1
  • 118
    • 0038561221 scopus 로고    scopus 로고
    • Rap1 translates chemokine signals to inte-grin activation, cell polarization, and motility across vascular endothelium under flow
    • Shimonaka, M., Katagiri, K., Nakayama, T., Fujita, N., Tsuruo, T., Yoshie, O., and Kinashi, T. (2003). Rap1 translates chemokine signals to inte-grin activation, cell polarization, and motility across vascular endothelium under flow. J. Cell Biol. 161, 417-427.
    • (2003) J. Cell Biol. , vol.161 , pp. 417-427
    • Shimonaka, M.1    Katagiri, K.2    Nakayama, T.3    Fujita, N.4    Tsuruo, T.5    Yoshie, O.6    Kinashi, T.7
  • 121
    • 77955105110 scopus 로고    scopus 로고
    • Quantitative proteome analysis of detergent-resistant membranes identifies the differential regulation of protein kinase C isoforms in apop-totic T cells
    • Solstad, T., Bjorgo, E., Koehler, C. J., Strozynski, M., Torgersen, K. M., Tasken, K., and Thiede, B. (2010). Quantitative proteome analysis of detergent-resistant membranes identifies the differential regulation of protein kinase C isoforms in apop-totic T cells. Proteomics 10, 2758-2768.
    • (2010) Proteomics , vol.10 , pp. 2758-2768
    • Solstad, T.1    Bjorgo, E.2    Koehler, C.J.3    Strozynski, M.4    Torgersen, K.M.5    Tasken, K.6    Thiede, B.7
  • 124
    • 0032032140 scopus 로고    scopus 로고
    • Different protein kinase C isoenzymes regulate IL-2 receptor expression or IL-2 synthesis in human lymphocytes stimulated via the TCR
    • Szamel, M., Appel, A., Schwinzer, R., and Resch, K. (1998). Different protein kinase C isoenzymes regulate IL-2 receptor expression or IL-2 synthesis in human lymphocytes stimulated via the TCR. J. Immunol. 160, 2207-2214.
    • (1998) J. Immunol. , vol.160 , pp. 2207-2214
    • Szamel, M.1    Appel, A.2    Schwinzer, R.3    Resch, K.4
  • 125
    • 0017745032 scopus 로고
    • Studies on a cyclic nucleotide-independent protein kinase and its proenzyme in mammalian tissues. I. Purification and characterization of an active enzyme from bovine cerebellum
    • Takai, Y, Kishimoto, A., Inoue, M., and Nishizuka, Y (1977). Studies on a cyclic nucleotide-independent protein kinase and its proenzyme in mammalian tissues. I. Purification and characterization of an active enzyme from bovine cerebellum. J. Biol. Chem. 252, 7603-7609.
    • (1977) J. Biol. Chem. , vol.252 , pp. 7603-7609
    • Takai, Y.1    Kishimoto, A.2    Inoue, M.3    Nishizuka, Y.4
  • 126
    • 33644512418 scopus 로고    scopus 로고
    • Resistance to experimental autoimmune encephalomyelitis and impaired IL-17 production in protein kinase C 9-deficient mice
    • Tan, S. L., Zhao, J., Bi, C, Chen, X. C, Hepburn, D. L., Wang, J., Sedgwick, J. D., Chintalacharuvu, S. R., and Na, S. (2006). Resistance to experimental autoimmune encephalomyelitis and impaired IL-17 production in protein kinase C 9-deficient mice. J. Immunol. 176, 2872-2879.
    • (2006) J. Immunol. , vol.176 , pp. 2872-2879
    • Tan, S.L.1    Zhao, J.2    Bi, C.3    Chen, X.C.4    Hepburn, D.L.5    Wang, J.6    Sedgwick, J.D.7    Chintalacharuvu, S.R.8    Na, S.9
  • 127
    • 77951638740 scopus 로고    scopus 로고
    • Expression of Helios, an Ikaros transcription factor family member, differentiates thymic-derived from peripherally induced Foxp3+ T regulatory cells
    • Thornton, A. M., Korty, P. E., Tran, D. Q., Wohlfert, E. A., Murray, P. E., Belkaid, Y, and Shevach, E. M. (2010). Expression of Helios, an Ikaros transcription factor family member, differentiates thymic-derived from peripherally induced Foxp3+ T regulatory cells. J. Immunol. 184, 3433-3441.
    • (2010) J. Immunol. , vol.184 , pp. 3433-3441
    • Thornton, A.M.1    Korty, P.E.2    Tran, D.Q.3    Wohlfert, E.A.4    Murray, P.E.5    Belkaid, Y.6    Shevach, E.M.7
  • 128
    • 2442586505 scopus 로고    scopus 로고
    • Protein kinase C β is dispensable for TCR-signaling
    • Thuille, N., Gruber, T., Bock, G., Leitges, M., and Baier, G. (2004). Protein kinase C β is dispensable for TCR-signaling. Mol. Immunol. 41, 385-390.
    • (2004) Mol. Immunol. , vol.41 , pp. 385-390
    • Thuille, N.1    Gruber, T.2    Bock, G.3    Leitges, M.4    Baier, G.5
  • 130
    • 34247592034 scopus 로고    scopus 로고
    • CD4 ligation induces activation of protein kinase C t, and phosphoinositide-dependent-protein kinase-1, two kinases required for down-regulation of LFA-1-mediated adhesion
    • Trucy, M., Barbat, C, Fischer, A., and Mazerolles, F. (2006). CD4 ligation induces activation of protein kinase C t, and phosphoinositide-dependent-protein kinase-1, two kinases required for down-regulation of LFA-1-mediated adhesion. Cell Immunol 244, 33-42.
    • (2006) Cell Immunol , vol.244 , pp. 33-42
    • Trucy, M.1    Barbat, C.2    Fischer, A.3    Mazerolles, F.4
  • 132
    • 0029963890 scopus 로고    scopus 로고
    • The eta isoform of protein kinase C mediates transcriptional activation of the human transglutaminase 1 gene
    • Ueda, E., Ohno, S., Kuroki, T., Livneh, E., Yamada, K., Yaman-ishi, K., and Yasuno, H. (1996). The eta isoform of protein kinase C mediates transcriptional activation of the human transglutaminase 1 gene. J. Biol. Chem. 271, 9790-9794.
    • (1996) J. Biol. Chem. , vol.271 , pp. 9790-9794
    • Ueda, E.1    Ohno, S.2    Kuroki, T.3    Livneh, E.4    Yamada, K.5    Yaman-ishi, K.6    Yasuno, H.7
  • 133
    • 0032534682 scopus 로고    scopus 로고
    • Inside the crawling T cell: leukocyte function-associated antigen-1 cross-linking is associated with microtubule-directed translocation of protein kinase C isoenzymes β(I) and S
    • Volkov, Y, Long, A., and Kelle-her, D. (1998). Inside the crawling T cell: leukocyte function-associated antigen-1 cross-linking is associated with microtubule-directed translocation of protein kinase C isoenzymes β(I) and S. J. Immunol. 161, 6487-6495.
    • (1998) J. Immunol. , vol.161 , pp. 6487-6495
    • Volkov, Y.1    Long, A.2    Kelle-her, D.3
  • 134
    • 0035377216 scopus 로고    scopus 로고
    • Crucial importance of PKCβ(I) in LFA-1-mediated locomotion of activated T cells
    • Volkov, Y, Long, A., Mcgrath, S., Ni Eidhin, D., and Kelleher, D. (2001). Crucial importance of PKCβ(I) in LFA-1-mediated locomotion of activated T cells. Nat. Immunol. 2, 508-514.
    • (2001) Nat. Immunol. , vol.2 , pp. 508-514
    • Volkov, Y.1    Long, A.2    Mcgrath, S.3    Ni Eidhin, D.4    Kelleher, D.5
  • 137
    • 33644986596 scopus 로고    scopus 로고
    • Parathyroid hormone activates PKCS and regulates osteoblastic differentiation via a PLC-independent pathway
    • Yang, D., Guo, J., Divieti, P., and Bringhurst, F. R. (2006). Parathyroid hormone activates PKCS and regulates osteoblastic differentiation via a PLC-independent pathway. Bone 38, 485-496.
    • (2006) Bone , vol.38 , pp. 485-496
    • Yang, D.1    Guo, J.2    Divieti, P.3    Bringhurst, F.R.4
  • 138
    • 79960894775 scopus 로고    scopus 로고
    • PKC9 function at the immunological synapse: prospects for therapeutic targeting
    • Zanin-Zhorov, A., Dustin, M. L., and Blazar, B. R. (2011). PKC9 function at the immunological synapse: prospects for therapeutic targeting. Trends Immunol. 32, 358-363.
    • (2011) Trends Immunol , vol.32 , pp. 358-363
    • Zanin-Zhorov, A.1    Dustin, M.L.2    Blazar, B.R.3
  • 139
    • 48949099697 scopus 로고    scopus 로고
    • Wogonin induced differentiation and G1 phase arrest of human U-937 leukemia cells via PKCS phosphorylation
    • Zhang, H. W., Yang, Y., Zhang, K., Qiang, L., Yang, L., Hu, Y., Wang, X. T., You, Q. D., and Guo, Q. L. (2008). Wogonin induced differentiation and G1 phase arrest of human U-937 leukemia cells via PKCS phosphorylation. Eur. J. Pharmacol. 591, 7-12.
    • (2008) Eur. J. Pharmacol. , vol.591 , pp. 7-12
    • Zhang, H.W.1    Yang, Y.2    Zhang, K.3    Qiang, L.4    Yang, L.5    Hu, Y.6    Wang, X.T.7    You, Q.D.8    Guo, Q.L.9
  • 140
    • 34247277666 scopus 로고    scopus 로고
    • Foxp3 in control of the regulatory T cell lineage
    • Zheng, Y, and Rudensky, A. Y (2007). Foxp3 in control of the regulatory T cell lineage. Nat. Immunol. 8, 457-462.
    • (2007) Nat. Immunol. , vol.8 , pp. 457-462
    • Zheng, Y.1    Rudensky, A.Y.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.