메뉴 건너뛰기




Volumn 4, Issue 4, 2012, Pages 110-118

Bacterial translocation and changes in the intestinal microbiome associated with alcoholic liver disease

Author keywords

Alcoholic liver disease; Bacterial translocation; Dysbiosis; Microbiome; Steatohepatitis

Indexed keywords


EID: 84874115025     PISSN: None     EISSN: 19485182     Source Type: Journal    
DOI: 10.4254/wjh.v4.i4.110     Document Type: Editorial
Times cited : (97)

References (93)
  • 1
    • 0027141271 scopus 로고
    • Alcohol consumption and alcoholic liver disease: evidence of a threshold level of effects of ethanol
    • Savolainen VT, Liesto K, Männikkö A, Penttilä A, Karhunen PJ. Alcohol consumption and alcoholic liver disease: evidence of a threshold level of effects of ethanol. Alcohol Clin Exp Res 1993; 17: 1112-1117
    • (1993) Alcohol Clin Exp Res , vol.17 , pp. 1112-1117
    • Savolainen, V.T.1    Liesto, K.2    Männikkö, A.3    Penttilä, A.4    Karhunen, P.J.5
  • 5
    • 0008731363 scopus 로고    scopus 로고
    • Infectious complications of cirrhosis
    • Brann OS. Infectious complications of cirrhosis. Curr Gastroenterol Rep 2001; 3: 285-292
    • (2001) Curr Gastroenterol Rep , vol.3 , pp. 285-292
    • Brann, O.S.1
  • 6
    • 34250828060 scopus 로고    scopus 로고
    • Bacterial infection-related morbidity and mortality in cirrhosis
    • Christou L, Pappas G, Falagas ME. Bacterial infection-related morbidity and mortality in cirrhosis. Am J Gastroenterol 2007; 102: 1510-1517
    • (2007) Am J Gastroenterol , vol.102 , pp. 1510-1517
    • Christou, L.1    Pappas, G.2    Falagas, M.E.3
  • 8
    • 40949083014 scopus 로고    scopus 로고
    • Bacterial DNA in patients with cirrhosis and noninfected ascites mimics the soluble immune response established in patients with spontaneous bacterial peritonitis
    • Francés R, Zapater P, González-Navajas JM, Muñoz C, Caño R, Moreu R, Pascual S, Bellot P, Pérez-Mateo M, Such J. Bacterial DNA in patients with cirrhosis and noninfected ascites mimics the soluble immune response established in patients with spontaneous bacterial peritonitis. Hepatology 2008; 47: 978-985
    • (2008) Hepatology , vol.47 , pp. 978-985
    • Francé, R.1    Zapater, P.2    González-Navajas, J.M.3    Muñoz, C.4    Caño, R.5    Moreu, R.6    Pascual, S.7    Bellot, P.8    Perez-Mateo, M.9    Such, J.10
  • 9
    • 0023896026 scopus 로고
    • Comparison of transloca-tion rates of various indigenous bacteria from the gastrointestinal tract to the mesenteric lymph node
    • Steffen EK, Berg RD, Deitch EA. Comparison of transloca-tion rates of various indigenous bacteria from the gastrointestinal tract to the mesenteric lymph node. J Infect Dis 1988; 157: 1032-1038
    • (1988) J Infect Dis , vol.157 , pp. 1032-1038
    • Steffen, E.K.1    Berg, R.D.2    Deitch, E.A.3
  • 10
    • 0036139042 scopus 로고    scopus 로고
    • Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis
    • Fernández J, Navasa M, Gómez J, Colmenero J, Vila J, Arroyo V, Rodés J. Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis. Hepatology 2002; 35: 140-148
    • (2002) Hepatology , vol.35 , pp. 140-148
    • Fernández, J.1    Navasa, M.2    Gómez, J.3    Colmenero, J.4    Vila, J.5    Arroyo, V.6    Rodés, J.7
  • 11
    • 0026078067 scopus 로고
    • Plasma endotoxin concentrations in patients with alcoholic and non-alcoholic liver disease: reevaluation with an improved chromogenic assay
    • Fukui H, Brauner B, Bode JC, Bode C. Plasma endotoxin concentrations in patients with alcoholic and non-alcoholic liver disease: reevaluation with an improved chromogenic assay. J Hepatol 1991; 12: 162-169
    • (1991) J Hepatol , vol.12 , pp. 162-169
    • Fukui, H.1    Brauner, B.2    Bode, J.C.3    Bode, C.4
  • 12
    • 0023145010 scopus 로고
    • Endotoxemia in patients with alcoholic and non-alcoholic cirrhosis and in subjects with no evidence of chronic liver disease following acute alcohol excess
    • Bode C, Kugler V, Bode JC. Endotoxemia in patients with alcoholic and non-alcoholic cirrhosis and in subjects with no evidence of chronic liver disease following acute alcohol excess. J Hepatol 1987; 4: 8-14
    • (1987) J Hepatol , vol.4 , pp. 8-14
    • Bode, C.1    Kugler, V.2    Bode, J.C.3
  • 13
    • 0036180617 scopus 로고    scopus 로고
    • Concentrations of lipopolysaccharide-binding protein, bactericidal/permeability-increasing protein, soluble CD14 and plasma lipids in relation to endotoxaemia in patients with alcoholic liver disease
    • Schäfer C, Parlesak A, Schütt C, Bode JC, Bode C. Concentrations of lipopolysaccharide-binding protein, bactericidal/permeability-increasing protein, soluble CD14 and plasma lipids in relation to endotoxaemia in patients with alcoholic liver disease. Alcohol Alcohol 2002; 37: 81-86
    • (2002) Alcohol Alcohol , vol.37 , pp. 81-86
    • Schäfer, C.1    Parlesak, A.2    Schütt, C.3    Bode, J.C.4    Bode, C.5
  • 15
    • 14244252178 scopus 로고    scopus 로고
    • Bacterial translocation (BT) in cirrhosis
    • Wiest R, Garcia-Tsao G. Bacterial translocation (BT) in cirrhosis. Hepatology 2005; 41: 422-433
    • (2005) Hepatology , vol.41 , pp. 422-433
    • Wiest, R.1    Garcia-Tsao, G.2
  • 16
    • 0034950477 scopus 로고    scopus 로고
    • Toll-like receptor 4 is involved in the mechanism of early alcohol-induced liver injury in mice
    • Uesugi T, Froh M, Arteel GE, Bradford BU, Thurman RG. Toll-like receptor 4 is involved in the mechanism of early alcohol-induced liver injury in mice. Hepatology 2001; 34: 101-108
    • (2001) Hepatology , vol.34 , pp. 101-108
    • Uesugi, T.1    Froh, M.2    Arteel, G.E.3    Bradford, B.U.4    Thurman, R.G.5
  • 18
    • 0030716183 scopus 로고    scopus 로고
    • Antibodies to tumor necrosis factor alfa attenuate hepatic necrosis and inflammation caused by chronic exposure to ethanol in the rat
    • Iimuro Y, Gallucci RM, Luster MI, Kono H, Thurman RG. Antibodies to tumor necrosis factor alfa attenuate hepatic necrosis and inflammation caused by chronic exposure to ethanol in the rat. Hepatology 1997; 26: 1530-1537
    • (1997) Hepatology , vol.26 , pp. 1530-1537
    • Iimuro, Y.1    Gallucci, R.M.2    Luster, M.I.3    Kono, H.4    Thurman, R.G.5
  • 20
    • 0035049639 scopus 로고    scopus 로고
    • Pro-and anti-inflammatory gene expression in the murine small intestine and liver after chronic exposure to alcohol
    • Fleming S, Toratani S, Shea-Donohue T, Kashiwabara Y, Vogel SN, Metcalf ES. Pro-and anti-inflammatory gene expression in the murine small intestine and liver after chronic exposure to alcohol. Alcohol Clin Exp Res 2001; 25: 579-589
    • (2001) Alcohol Clin Exp Res , vol.25 , pp. 579-589
    • Fleming, S.1    Toratani, S.2    Shea-Donohue, T.3    Kashiwabara, Y.4    Vogel, S.N.5    Metcalf, E.S.6
  • 21
    • 0028927862 scopus 로고
    • Chronic ethanol intake and burn injury: evidence for synergistic alteration in gut and immune integrity
    • Napolitano LM, Koruda MJ, Zimmerman K, McCowan K, Chang J, Meyer AA. Chronic ethanol intake and burn injury: evidence for synergistic alteration in gut and immune integrity. J Trauma 1995; 38: 198-207
    • (1995) J Trauma , vol.38 , pp. 198-207
    • Napolitano, L.M.1    Koruda, M.J.2    Zimmerman, K.3    McCowan, K.4    Chang, J.5    Meyer, A.A.6
  • 22
    • 0028796860 scopus 로고
    • Antibiotics prevent liver injury in rats following long-term exposure to ethanol
    • Adachi Y, Moore LE, Bradford BU, Gao W, Thurman RG. Antibiotics prevent liver injury in rats following long-term exposure to ethanol. Gastroenterology 1995; 108: 218-224
    • (1995) Gastroenterology , vol.108 , pp. 218-224
    • Adachi, Y.1    Moore, L.E.2    Bradford, B.U.3    Gao, W.4    Thurman, R.G.5
  • 23
    • 0027404469 scopus 로고
    • Severity of liver injury in experimental alcoholic liver disease. Correlation with plasma endotoxin, prostaglandin E2, leukotriene B4, and thromboxane B2
    • Nanji AA, Khettry U, Sadrzadeh SM, Yamanaka T. Severity of liver injury in experimental alcoholic liver disease. Correlation with plasma endotoxin, prostaglandin E2, leukotriene B4, and thromboxane B2. Am J Pathol 1993; 142: 367-373
    • (1993) Am J Pathol , vol.142 , pp. 367-373
    • Nanji, A.A.1    Khettry, U.2    Sadrzadeh, S.M.3    Yamanaka, T.4
  • 24
    • 0034073962 scopus 로고    scopus 로고
    • Effect of acute ethanol administration on the intestinal absorption of endotoxin in rats
    • Tamai H, Kato S, Horie Y, Ohki E, Yokoyama H, Ishii H. Effect of acute ethanol administration on the intestinal absorption of endotoxin in rats. Alcohol Clin Exp Res 2000; 24: 390-394
    • (2000) Alcohol Clin Exp Res , vol.24 , pp. 390-394
    • Tamai, H.1    Kato, S.2    Horie, Y.3    Ohki, E.4    Yokoyama, H.5    Ishii, H.6
  • 25
    • 0036708852 scopus 로고    scopus 로고
    • Bacterial translocation and peptidoglycan translocation by acute ethanol administration
    • Tabata T, Tani T, Endo Y, Hanasawa K. Bacterial translocation and peptidoglycan translocation by acute ethanol administration. J Gastroenterol 2002; 37: 726-731
    • (2002) J Gastroenterol , vol.37 , pp. 726-731
    • Tabata, T.1    Tani, T.2    Endo, Y.3    Hanasawa, K.4
  • 26
    • 0028934072 scopus 로고
    • Endotoxemia in patients with chronic liver diseases: relationship to severity of liver diseases, presence of esophageal varices, and hyperdynamic circulation
    • Lin RS, Lee FY, Lee SD, Tsai YT, Lin HC, Lu RH, Hsu WC, Huang CC, Wang SS, Lo KJ. Endotoxemia in patients with chronic liver diseases: relationship to severity of liver diseases, presence of esophageal varices, and hyperdynamic circulation. J Hepatol 1995; 22: 165-172
    • (1995) J Hepatol , vol.22 , pp. 165-172
    • Lin, R.S.1    Lee, F.Y.2    Lee, S.D.3    Tsai, Y.T.4    Lin, H.C.5    Lu, R.H.6    Hsu, W.C.7    Huang, C.C.8    Wang, S.S.9    Lo, K.J.10
  • 27
    • 32044469602 scopus 로고    scopus 로고
    • Activation of the innate immune system and alcoholic liver disease: effects of ethanol per se or enhanced intestinal translocation of bacterial toxins induced by ethanol?
    • Bode C, Bode JC. Activation of the innate immune system and alcoholic liver disease: effects of ethanol per se or enhanced intestinal translocation of bacterial toxins induced by ethanol? Alcohol Clin Exp Res 2005; 29: 166S-171S
    • (2005) Alcohol Clin Exp Res , vol.29
    • Bode, C.1    Bode, J.C.2
  • 28
    • 0342699553 scopus 로고    scopus 로고
    • Increased intestinal permeability to macromolecules and endotoxemia in patients with chronic alcohol abuse in different stages of alcohol-induced liver disease
    • Parlesak A, Schäfer C, Schütz T, Bode JC, Bode C. Increased intestinal permeability to macromolecules and endotoxemia in patients with chronic alcohol abuse in different stages of alcohol-induced liver disease. J Hepatol 2000; 32: 742-747
    • (2000) J Hepatol , vol.32 , pp. 742-747
    • Parlesak, A.1    Schäfer, C.2    Schütz, T.3    Bode, J.C.4    Bode, C.5
  • 29
    • 32944464648 scopus 로고    scopus 로고
    • Pathogen recognition and innate immunity
    • Akira S, Uematsu S, Takeuchi O. Pathogen recognition and innate immunity. Cell 2006; 124: 783-801
    • (2006) Cell , vol.124 , pp. 783-801
    • Akira, S.1    Uematsu, S.2    Takeuchi, O.3
  • 30
    • 77951260924 scopus 로고    scopus 로고
    • The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors
    • Kawai T, Akira S. The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat Immunol 2010; 11: 373-384
    • (2010) Nat Immunol , vol.11 , pp. 373-384
    • Kawai, T.1    Akira, S.2
  • 34
    • 54449092214 scopus 로고    scopus 로고
    • The critical role of toll-like receptor (TLR) 4 in alcoholic liver disease is independent of the common TLR adapter MyD88
    • Hritz I, Mandrekar P, Velayudham A, Catalano D, Dolganiuc A, Kodys K, Kurt-Jones E, Szabo G. The critical role of toll-like receptor (TLR) 4 in alcoholic liver disease is independent of the common TLR adapter MyD88. Hepatology 2008; 48: 1224-1231
    • (2008) Hepatology , vol.48 , pp. 1224-1231
    • Hritz, I.1    Mandrekar, P.2    Velayudham, A.3    Catalano, D.4    Dolganiuc, A.5    Kodys, K.6    Kurt-Jones, E.7    Szabo, G.8
  • 39
    • 2642553874 scopus 로고    scopus 로고
    • Recent Advances in Alcoholic Liver Disease I. Role of intestinal permeability and endotoxemia in alcoholic liver disease
    • Rao RK, Seth A, Sheth P. Recent Advances in Alcoholic Liver Disease I. Role of intestinal permeability and endotoxemia in alcoholic liver disease. Am J Physiol Gastrointest Liver Physiol 2004; 286: G881-G884
    • (2004) Am J Physiol Gastrointest Liver Physiol , vol.286
    • Rao, R.K.1    Seth, A.2    Sheth, P.3
  • 42
    • 33645449666 scopus 로고    scopus 로고
    • Impairment of the intestinal barrier by ethanol involves enteric microflora and mast cell activation in rodents
    • Ferrier L, Bérard F, Debrauwer L, Chabo C, Langella P, Buéno L, Fioramonti J. Impairment of the intestinal barrier by ethanol involves enteric microflora and mast cell activation in rodents. Am J Pathol 2006; 168: 1148-1154
    • (2006) Am J Pathol , vol.168 , pp. 1148-1154
    • Ferrier, L.1    Bérard, F.2    Debrauwer, L.3    Chabo, C.4    Langella, P.5    Buéno, L.6    Fioramonti, J.7
  • 43
    • 59549106331 scopus 로고    scopus 로고
    • Evidence that chronic alcohol exposure promotes intestinal oxidative stress, intestinal hyperpermeability and endotoxemia prior to development of alcoholic steatohepatitis in rats
    • Keshavarzian A, Farhadi A, Forsyth CB, Rangan J, Jakate S, Shaikh M, Banan A, Fields JZ. Evidence that chronic alcohol exposure promotes intestinal oxidative stress, intestinal hyperpermeability and endotoxemia prior to development of alcoholic steatohepatitis in rats. J Hepatol 2009; 50: 538-547
    • (2009) J Hepatol , vol.50 , pp. 538-547
    • Keshavarzian, A.1    Farhadi, A.2    Forsyth, C.B.3    Rangan, J.4    Jakate, S.5    Shaikh, M.6    Banan, A.7    Fields, J.Z.8
  • 44
    • 0035138847 scopus 로고    scopus 로고
    • Intragastric ethanol infusion model for cellular and molecular studies of alcoholic liver disease
    • French SW. Intragastric ethanol infusion model for cellular and molecular studies of alcoholic liver disease. J Biomed Sci 2001; 8: 20-27
    • (2001) J Biomed Sci , vol.8 , pp. 20-27
    • French, S.W.1
  • 45
    • 70350509805 scopus 로고    scopus 로고
    • Intestinal mucosal barrier function in health and disease
    • Turner JR. Intestinal mucosal barrier function in health and disease. Nat Rev Immunol 2009; 9: 799-809
    • (2009) Nat Rev Immunol , vol.9 , pp. 799-809
    • Turner, J.R.1
  • 47
    • 0021352090 scopus 로고
    • The leaky gut of alcoholism: possible route of entry for toxic compounds
    • Bjarnason I, Peters TJ, Wise RJ. The leaky gut of alcoholism: possible route of entry for toxic compounds. Lancet 1984; 1: 179-182
    • (1984) Lancet , vol.1 , pp. 179-182
    • Bjarnason, I.1    Peters, T.J.2    Wise, R.J.3
  • 48
    • 0031761303 scopus 로고    scopus 로고
    • Acetaldehyde-induced increase in paracellular permeability in Caco-2 cell monolayer
    • Rao RK. Acetaldehyde-induced increase in paracellular permeability in Caco-2 cell monolayer. Alcohol Clin Exp Res 1998; 22: 1724-1730
    • (1998) Alcohol Clin Exp Res , vol.22 , pp. 1724-1730
    • Rao, R.K.1
  • 49
    • 22544451542 scopus 로고    scopus 로고
    • Acetaldehyde disrupts tight junctions and adherens junctions in human colonic mucosa: protection by EGF and L-glutamine
    • Basuroy S, Sheth P, Mansbach CM, Rao RK. Acetaldehyde disrupts tight junctions and adherens junctions in human colonic mucosa: protection by EGF and L-glutamine. Am J Physiol Gastrointest Liver Physiol 2005; 289: G367-G375
    • (2005) Am J Physiol Gastrointest Liver Physiol , vol.289
    • Basuroy, S.1    Sheth, P.2    Mansbach, C.M.3    Rao, R.K.4
  • 50
    • 0025136962 scopus 로고
    • Hepatic inflammation in rats with experimental small intestinal bacterial overgrowth
    • Lichtman SN, Sartor RB, Keku J, Schwab JH. Hepatic inflammation in rats with experimental small intestinal bacterial overgrowth. Gastroenterology 1990; 98: 414-423
    • (1990) Gastroenterology , vol.98 , pp. 414-423
    • Lichtman, S.N.1    Sartor, R.B.2    Keku, J.3    Schwab, J.H.4
  • 53
    • 0030874289 scopus 로고    scopus 로고
    • Intestinal bacterial overgrowth and bacterial translocation in cirrhotic rats with ascites
    • Guarner C, Runyon BA, Young S, Heck M, Sheikh MY. Intestinal bacterial overgrowth and bacterial translocation in cirrhotic rats with ascites. J Hepatol 1997; 26: 1372-1378
    • (1997) J Hepatol , vol.26 , pp. 1372-1378
    • Guarner, C.1    Runyon, B.A.2    Young, S.3    Heck, M.4    Sheikh, M.Y.5
  • 54
    • 33645327743 scopus 로고    scopus 로고
    • Role of intestinal bacterial overgrowth and intestinal motility in bacterial translocation in experimental cirrhosis
    • Sánchez E, Casafont F, Guerra A, de Benito I, Pons-Romero F. Role of intestinal bacterial overgrowth and intestinal motility in bacterial translocation in experimental cirrhosis. Rev Esp Enferm Dig 2005; 97: 805-814
    • (2005) Rev Esp Enferm Dig , vol.97 , pp. 805-814
    • Sánchez, E.1    Casafont, F.2    Guerra, A.3    de Benito, I.4    Pons-Romero, F.5
  • 55
    • 0029064469 scopus 로고
    • Bacterial translocation to mesenteric lymph nodes is increased in cirrhotic rats with ascites
    • Garcia-Tsao G, Lee FY, Barden GE, Cartun R, West AB. Bacterial translocation to mesenteric lymph nodes is increased in cirrhotic rats with ascites. Gastroenterology 1995; 108: 1835-1841
    • (1995) Gastroenterology , vol.108 , pp. 1835-1841
    • Garcia-Tsao, G.1    Lee, F.Y.2    Barden, G.E.3    Cartun, R.4    West, A.B.5
  • 56
    • 0028149418 scopus 로고
    • Translocation of gut bacteria in rats with cirrhosis to mesenteric lymph nodes partially explains the pathogenesis of spontaneous bacterial peritonitis
    • Runyon BA, Squier S, Borzio M. Translocation of gut bacteria in rats with cirrhosis to mesenteric lymph nodes partially explains the pathogenesis of spontaneous bacterial peritonitis. J Hepatol 1994; 21: 792-796
    • (1994) J Hepatol , vol.21 , pp. 792-796
    • Runyon, B.A.1    Squier, S.2    Borzio, M.3
  • 59
    • 77449131229 scopus 로고    scopus 로고
    • Small-intestinal bacterial overgrowth in cirrhosis is related to the severity of liver disease
    • Pande C, Kumar A, Sarin SK. Small-intestinal bacterial overgrowth in cirrhosis is related to the severity of liver disease. Aliment Pharmacol Ther 2009; 29: 1273-1281
    • (2009) Aliment Pharmacol Ther , vol.29 , pp. 1273-1281
    • Pande, C.1    Kumar, A.2    Sarin, S.K.3
  • 62
    • 77953638458 scopus 로고    scopus 로고
    • Association between small intestinal bacterial overgrowth and peripheral bacterial DNA in cirrhotic patients
    • Jun DW, Kim KT, Lee OY, Chae JD, Son BK, Kim SH, Jo YJ, Park YS. Association between small intestinal bacterial overgrowth and peripheral bacterial DNA in cirrhotic patients. Dig Dis Sci 2010; 55: 1465-1471
    • (2010) Dig Dis Sci , vol.55 , pp. 1465-1471
    • Jun, D.W.1    Kim, K.T.2    Lee, O.Y.3    Chae, J.D.4    Son, B.K.5    Kim, S.H.6    Jo, Y.J.7    Park, Y.S.8
  • 64
    • 2342640188 scopus 로고    scopus 로고
    • Intestinal microflora in patients with liver cirrhosis
    • Zhao HY, Wang HJ, Lu Z, Xu SZ. Intestinal microflora in patients with liver cirrhosis. Chin J Dig Dis. 2004; 5: 64-67
    • (2004) Chin J Dig Dis. , vol.5 , pp. 64-67
    • Zhao, H.Y.1    Wang, H.J.2    Lu, Z.3    Xu, S.Z.4
  • 67
    • 0031759395 scopus 로고    scopus 로고
    • Small intestine dysmotility and bacterial overgrowth in cirrhotic patients with spontaneous bacterial peritonitis
    • Chang CS, Chen GH, Lien HC, Yeh HZ. Small intestine dysmotility and bacterial overgrowth in cirrhotic patients with spontaneous bacterial peritonitis. Hepatology 1998; 28: 1187-1190
    • (1998) Hepatology , vol.28 , pp. 1187-1190
    • Chang, C.S.1    Chen, G.H.2    Lien, H.C.3    Yeh, H.Z.4
  • 68
    • 0030897255 scopus 로고    scopus 로고
    • Altered small bowel motility in patients with liver cirrhosis depends on severity of liver disease
    • Madrid AM, Cumsille F, Defilippi C. Altered small bowel motility in patients with liver cirrhosis depends on severity of liver disease. Dig Dis Sci 1997; 42: 738-742
    • (1997) Dig Dis Sci , vol.42 , pp. 738-742
    • Madrid, A.M.1    Cumsille, F.2    Defilippi, C.3
  • 70
    • 77957345947 scopus 로고    scopus 로고
    • Role of small intestinal bacterial overgrowth and delayed gastrointestinal transit time in cirrhotic patients with minimal hepatic encephalopathy
    • Gupta A, Dhiman RK, Kumari S, Rana S, Agarwal R, Duseja A, Chawla Y. Role of small intestinal bacterial overgrowth and delayed gastrointestinal transit time in cirrhotic patients with minimal hepatic encephalopathy. J Hepatol 2010; 53: 849-855]
    • (2010) J Hepatol , vol.53
    • Gupta, A.1    Dhiman, R.K.2    Kumari, S.3    Rana, S.4    Agarwal, R.5    Duseja, A.6    Chawla, Y.7
  • 71
    • 0035046242 scopus 로고    scopus 로고
    • Long-Term treatment with cisapride and antibiotics in liver cirrhosis: effect on small intestinal motility, bacterial overgrowth, and liver function
    • Madrid AM, Hurtado C, Venegas M, Cumsille F, Defilippi C. Long-Term treatment with cisapride and antibiotics in liver cirrhosis: effect on small intestinal motility, bacterial overgrowth, and liver function. Am J Gastroenterol 2001; 96: 1251-1255
    • (2001) Am J Gastroenterol , vol.96 , pp. 1251-1255
    • Madrid, A.M.1    Hurtado, C.2    Venegas, M.3    Cumsille, F.4    Defilippi, C.5
  • 72
    • 0027441084 scopus 로고
    • A syndrome of cirrhosis, achlorhydria, small intestinal bacterial overgrowth, and fat malabsorption
    • Shindo K, Machida M, Miyakawa K, Fukumura M. A syndrome of cirrhosis, achlorhydria, small intestinal bacterial overgrowth, and fat malabsorption. Am J Gastroenterol 1993; 88: 2084-2091
    • (1993) Am J Gastroenterol , vol.88 , pp. 2084-2091
    • Shindo, K.1    Machida, M.2    Miyakawa, K.3    Fukumura, M.4
  • 74
    • 65449128399 scopus 로고    scopus 로고
    • Patterns and scales in gastrointestinal microbial ecology
    • Camp JG, Kanther M, Semova I, Rawls JF. Patterns and scales in gastrointestinal microbial ecology. Gastroenterology 2009; 136: 1989-2002
    • (2009) Gastroenterology , vol.136 , pp. 1989-2002
    • Camp, J.G.1    Kanther, M.2    Semova, I.3    Rawls, J.F.4
  • 77
    • 33845901507 scopus 로고    scopus 로고
    • Microbial ecology: human gut microbes associated with obesity
    • Ley RE, Turnbaugh PJ, Klein S, Gordon JI. Microbial ecology: human gut microbes associated with obesity. Nature 2006; 444: 1022-1023
    • (2006) Nature , vol.444 , pp. 1022-1023
    • Ley, R.E.1    Turnbaugh, P.J.2    Klein, S.3    Gordon, J.I.4
  • 78
    • 35348857386 scopus 로고    scopus 로고
    • Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases
    • Frank DN, St Amand AL, Feldman RA, Boedeker EC, Harpaz N, Pace NR. Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases. Proc Natl Acad Sci USA 2007; 104: 13780-13785
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 13780-13785
    • Frank, D.N.1    St Amand, A.L.2    Feldman, R.A.3    Boedeker, E.C.4    Harpaz, N.5    Pace, N.R.6
  • 79
    • 70349335851 scopus 로고    scopus 로고
    • Intestinal dysbiosis: a possible mechanism of alcohol-induced endotoxemia and alcoholic steatohepatitis in rats
    • Mutlu E, Keshavarzian A, Engen P, Forsyth CB, Sikaroodi M, Gillevet P. Intestinal dysbiosis: a possible mechanism of alcohol-induced endotoxemia and alcoholic steatohepatitis in rats. Alcohol Clin Exp Res 2009; 33: 1836-1846
    • (2009) Alcohol Clin Exp Res , vol.33 , pp. 1836-1846
    • Mutlu, E.1    Keshavarzian, A.2    Engen, P.3    Forsyth, C.B.4    Sikaroodi, M.5    Gillevet, P.6
  • 80
    • 0028220726 scopus 로고
    • Lactobacillus feeding reduces endotoxemia and severity of experimental alcoholic liver (disease)
    • Nanji AA, Khettry U, Sadrzadeh SM. Lactobacillus feeding reduces endotoxemia and severity of experimental alcoholic liver (disease). Proc Soc Exp Biol Med 1994; 205: 243-247
    • (1994) Proc Soc Exp Biol Med , vol.205 , pp. 243-247
    • Nanji, A.A.1    Khettry, U.2    Sadrzadeh, S.M.3
  • 81
    • 61349161828 scopus 로고    scopus 로고
    • Lactobacillus GG treatment ameliorates alcohol-induced intestinal oxidative stress, gut leakiness, and liverinjury in a rat model of alcoholic steatohepatitis
    • Forsyth CB, Farhadi A, Jakate SM, Tang Y, Shaikh M, Keshavarzian A. Lactobacillus GG treatment ameliorates alcohol-induced intestinal oxidative stress, gut leakiness, and liverinjury in a rat model of alcoholic steatohepatitis. Alcohol 2009; 43: 163-172
    • (2009) Alcohol , vol.43 , pp. 163-172
    • Forsyth, C.B.1    Farhadi, A.2    Jakate, S.M.3    Tang, Y.4    Shaikh, M.5    Keshavarzian, A.6
  • 82
    • 5444248493 scopus 로고    scopus 로고
    • Akkermansia muciniphila gen. nov., sp. nov., a human intestinal mucin-degrading bacterium
    • Derrien M, Vaughan EE, Plugge CM, de Vos WM. Akkermansia muciniphila gen. nov., sp. nov., a human intestinal mucin-degrading bacterium. Int J Syst Evol Microbiol 2004; 54: 1469-1476
    • (2004) Int J Syst Evol Microbiol , vol.54 , pp. 1469-1476
    • Derrien, M.1    Vaughan, E.E.2    Plugge, C.M.3    de Vos, W.M.4
  • 83
    • 40549106737 scopus 로고    scopus 로고
    • The Mucin degrader Akkermansia muciniphila is an abundant resident of the human intestinal tract
    • Derrien M, Collado MC, Ben-Amor K, Salminen S, de Vos WM. The Mucin degrader Akkermansia muciniphila is an abundant resident of the human intestinal tract. Appl Environ Microbiol 2008; 74: 1646-1648
    • (2008) Appl Environ Microbiol , vol.74 , pp. 1646-1648
    • Derrien, M.1    Collado, M.C.2    Ben-Amor, K.3    Salminen, S.4    de Vos, W.M.5
  • 84
    • 38449104720 scopus 로고    scopus 로고
    • Intestinal integrity and Akkermansia muciniphila, a mucin-degrading member of the intestinal microbiota present in infants, adults, and the elderly
    • Collado MC, Derrien M, Isolauri E, de Vos WM, Salminen S. Intestinal integrity and Akkermansia muciniphila, a mucin-degrading member of the intestinal microbiota present in infants, adults, and the elderly. Appl Environ Microbiol 2007; 73: 7767-7770
    • (2007) Appl Environ Microbiol , vol.73 , pp. 7767-7770
    • Collado, M.C.1    Derrien, M.2    Isolauri, E.3    de Vos, W.M.4    Salminen, S.5
  • 86
    • 53149099016 scopus 로고    scopus 로고
    • Prebiotics as gut microflora management tools
    • Gibson GR. Prebiotics as gut microflora management tools. J Clin Gastroenterol 2008; 42 Suppl 2: S75-S79
    • (2008) J Clin Gastroenterol , vol.42 , Issue.SUPPL. 2
    • Gibson, G.R.1
  • 87
    • 76149116164 scopus 로고    scopus 로고
    • Probiotics and gut health: a special focus on liver diseases
    • Gratz SW, Mykkanen H, El-Nezami HS. Probiotics and gut health: a special focus on liver diseases. World J Gastroenterol 2010; 16: 403-410
    • (2010) World J Gastroenterol , vol.16 , pp. 403-410
    • Gratz, S.W.1    Mykkanen, H.2    El-Nezami, H.S.3
  • 90
    • 43049181923 scopus 로고    scopus 로고
    • Effect of probiotic treatment on deranged neutrophil function and cytokine responses in patients with compensated alcoholic cirrhosis
    • Stadlbauer V, Mookerjee RP, Hodges S, Wright GA, Davies NA, Jalan R. Effect of probiotic treatment on deranged neutrophil function and cytokine responses in patients with compensated alcoholic cirrhosis. J Hepatol 2008; 48: 945-951
    • (2008) J Hepatol , vol.48 , pp. 945-951
    • Stadlbauer, V.1    Mookerjee, R.P.2    Hodges, S.3    Wright, G.A.4    Davies, N.A.5    Jalan, R.6
  • 92
    • 66749115646 scopus 로고    scopus 로고
    • Oats supplementation prevents alcohol-induced gut leakiness in rats by preventing alcohol-induced oxidative tissue damage
    • Tang Y, Forsyth CB, Banan A, Fields JZ, Keshavarzian A. Oats supplementation prevents alcohol-induced gut leakiness in rats by preventing alcohol-induced oxidative tissue damage. J Pharmacol Exp Ther 2009; 329: 952-958
    • (2009) J Pharmacol Exp Ther , vol.329 , pp. 952-958
    • Tang, Y.1    Forsyth, C.B.2    Banan, A.3    Fields, J.Z.4    Keshavarzian, A.5
  • 93
    • 33644818540 scopus 로고    scopus 로고
    • Experimental acute alcohol pancreatitis-related liver damage and endotoxemia: synbiotics but not metronidazole have a protective effect
    • Marotta F, Barreto R, Wu CC, Naito Y, Gelosa F, Lorenzetti A, Yoshioka M, Fesce E. Experimental acute alcohol pancreatitis-related liver damage and endotoxemia: synbiotics but not metronidazole have a protective effect. Chin J Dig Dis 2005; 6: 193-197
    • (2005) Chin J Dig Dis , vol.6 , pp. 193-197
    • Marotta, F.1    Barreto, R.2    Wu, C.C.3    Naito, Y.4    Gelosa, F.5    Lorenzetti, A.6    Yoshioka, M.7    Fesce, E.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.