Multiparametric homogeneous method for identification of ligand binding to G protein-coupled receptors: Receptor-ligand binding and β-arrestin assay

Analytical Chemistry

Volumn 85, Issue 4, 2013, Pages 2276-2281

  Kopra, Kari ^a   Kainulainen, Markus ^a,b   Mikkonen, Piia ^a   Rozwandowicz Jansen, Anita ^a   Hänninen, Pekka ^a   Härmä, Harri ^a  

^a UNIVERSITY OF TURKU   (Finland)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENERGIC RECEPTORS; ALPRENOLOL; ARRESTINS; ASSAY METHODS; BISOPROLOL; CELL-BASED; COMPLEMENTATION; DETECTION TECHNOLOGY; FRAGMENT COMPLEMENTATION; FUNCTIONAL ASSAYS; G PROTEIN COUPLED RECEPTORS; HOMOGENEOUS ASSAYS; HOMOGENEOUS METHOD; INTACT CELLS; LIGAND BINDING; RECEPTOR ACTIVATION; RECEPTOR BINDING; RECEPTOR-LIGAND BINDING; RECEPTOR-LIGAND INTERACTIONS; RESONANCE ENERGY TRANSFER; SALMETEROL; SIGNAL-TO-BACKGROUND RATIO; TERBUTALINE; TIME-RESOLVED LUMINESCENCE;

DRUG PRODUCTS; ENERGY TRANSFER; ENZYME INHIBITION; QUENCHING;

LIGANDS;

BETA 2 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR BLOCKING AGENT; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; BETA ARRESTIN; LIGAND; RETINA S ANTIGEN;

ANIMAL; ARTICLE; CHEMISTRY; CHO CELL; CRICETULUS; FLUORESCENCE RESONANCE ENERGY TRANSFER; HAMSTER; HUMAN; METABOLISM; PROTEIN BINDING;

ADRENERGIC BETA-2 RECEPTOR AGONISTS; ADRENERGIC BETA-2 RECEPTOR ANTAGONISTS; ANIMALS; ARRESTINS; CHO CELLS; CRICETINAE; CRICETULUS; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMANS; LIGANDS; PROTEIN BINDING; RECEPTORS, ADRENERGIC, BETA-2;

EID: 84874042230     PISSN: 00032700     EISSN: 15206882     Source Type: Journal    
DOI: 10.1021/ac303215r     Document Type: Article

References (43)

1. Overington, J. P.; Al-Lazikani, B.; Hopkins, A. L. Nat. Rev. Drug Discovery 2006, 5, 993-996
2. Fredriksson, R.; Lagerström, M. C.; Lundin, L. G.; Schiöth, H. B. Mol. Pharmacol. 2003, 63, 1256-1272
3. Stevens, R. C.; Cherezov, V.; Katritch, V.; Abagyan, R.; Kuhn, P.; Rosen, H.; Wüthrich, K. Nat. Rev. Drug Discovery 2012, 12, 25-34
4. Drake, M. T.; Shenoy, S. K.; Lefkowitz, R. J. Circ. Res. 2006, 99, 570-582
5. Johnson, M. J. Allergy Clin. Immunol. 2006, 117, 18-24
6. Benovic, J. L. J. Allergy Clin. Immunol. 2002, 110, S229-S235
7. Deshpande, D. A.; Penn, R. B. Cell. Signalling 2006, 18, 2105-2120
8. Kelly, E.; Bailey, C. P.; Henderson, G. Br. J. Pharmacol. 2008, 153, S379-S388
9. Taylor, M. R. Pharmacogenomics J. 2007, 7, 29-37
10. Rasmussen, S. G.; Choi, H. J.; Rosenbaum, D. M.; Kobilka, T. S.; Thian, F. S.; Edwards, P. C.; Burghammer, M.; Ratnala, V. R. P.; Sanishvili, R.; Fischetti, R. F.; Schertler, G. F. X.; Weis, W. I.; Kobilka, B. K. Nature 2007, 450, 383-387
11. Rosenbaum, D. M.; Cherezov, V.; Hanson, M. A.; Rasmussen, S. G. F.; Thian, F. S.; Kobilka, T. S.; Choi, H. J.; Yao, X. J.; Weis, W. I.; Stevens, R. C.; Kobilka, B. K. Science 2007, 318, 1266-1273
12. Rasmussen, S. G.; DeVree, B. T.; Zou, Y.; Kruse, A. C.; Chung, K. Y.; Kobilka, T. S.; Thian, F. S.; Chae, P. S.; Pardon, E.; Calinski, D.; Mathiesen, J. M.; Shah, S. T. A.; Lyons, J. A.; Caffrey, M.; Gellman, S. H.; Steyaert, J.; Skiniotis, G.; Weis, W. I.; Sunahara, R. K.; Kobilka, B. K. Nature 2011, 477, 549-557
13. Gabriel, D.; Vernier, M.; Pfeifer, M. J.; Dasen, B.; Tenaillon, L.; Bouhelal, R. Assay Drug Dev. Technol. 2003, 1, 291-303
14. Thomsen, W.; Frazer, J.; Unett, D. Curr. Opin. Biotechnol. 2005, 16, 655-665
15. Zhang, R.; Xie, X. Acta Pharmacol. Sin. 2012, 33, 372-384
16. Glickman, J. F.; Schmid, A.; Ferrand, S. Assay Drug Dev. Technol. 2008, 6, 433-455
17. Seethala, R.; Prabhavathi, F. Homogeneous Assays: AlphaScreen. In Handbook of Drug Screening, 1 st ed.; Marcel Dekker: New York, 2001; pp 106-110.
18. Glickman, J. F.; Wu, X.; Mercuri, R.; Illy, C.; Bowen, B. R.; He, Y.; Sills, M. J. Biomol. Screening 2002, 7, 3-10
19. Hemmilä, I.; Webb, S. Drug Discovery Today 1997, 2, 373-381
20. Degorce, F.; Card, A.; Soh, S.; Trinquet, E.; Knapik, G. P.; Xie, B. Curr. Chem. Genomics 2009, 3, 22-32
21. Gribbon, P.; Sewing, A. Drug Discovery Today 2003, 8, 1035-1043
22. LANCE cAMP Kit Manual; PerkinElmer Life and Analytical Sciences: Boston, MA, 2010.
23. Gagne, A.; Banks, P.; Hurt, S. D. J. Recept. Signal Transduction Res. 2002, 22, 333-343
24. Smith, D. S.; Eremin, S. A. Anal. Bioanal. Chem. 2008, 391, 1499-1507
25. Ma, H.; Deacon, S.; Horiuchi, K. Expert Opin. Drug Discovery 2008, 3, 607-621
26. Härmä, H.; Rozwandowicz-Jansen, A.; Martikkala, E.; Frang, H.; Hemmilä, I.; Sahlberg, N.; Fey, V.; Perälä, M.; Hänninen, P. J. Biomol. Screening 2009, 14, 936-943
27. Martikkala, E.; Rozwandowicz-Jansen, A.; Hänninen, P.; Petäjä-Repo, U.; Härmä, H. J. Biomol. Screening 2011, 16, 356-362
28. Rozwandowicz-Jansen, A.; Laurila, J.; Martikkala, E.; Frang, H.; Hemmilä, I.; Scheinin, M.; Hänninen, P.; Härmä, H. J. Biomol. Screening 2010, 15, 261-267
29. Luttrell, L. M.; Lefkowitz, R. J. J. Cell Sci. 2002, 115, 455-465
30. Lefkowitz, R. J.; Shenoy, S. K. Science 2005, 308, 512-517
31. Rossi, F.; Charlton, C. A.; Blau, H. M. Proc. Natl. Acad. Sci. U.S.A. 1997, 94, 8405-8410
32. Yan, Y. X.; Boldt-Houle, D. M.; Tillotson, B. P.; Gee, M. A.; D'Eon, B. J.; Chang, X. J.; Olesen, C. E.; Palmer, M. A. J. Biomol. Screening 2002, 7, 451-459
33. Zwier, J. M.; Roux, T.; Cottet, M.; Durroux, T.; Douzon, S.; Bdioui, S.; Gregor, N.; Bourrier, E.; Oueslati, N.; Nicolas, L.; Tinel, N.; Boisseau, C.; Yverneau, P.; Cherrier-Savournin, F.; Fink, M.; Trinquet, T. J. Biomol. Screening 2010, 15, 1248-1259
34. Reiner, S.; Ambrosio, M.; Hoffmann, C.; Lohse, M. J. J. Biol. Chem. 2010, 285, 36188-36198
35. DiPilato, L. M.; Zhang, J. Mol. BioSyst. 2009, 5, 832-837
36. Martikkala, E.; Lehmusto, M.; Lilja, M.; Rozwandowicz-Jansen, A.; Lunden, J.; Tomohiro, T.; Hänninen, P.; Petäjä-Repo, U.; Härmä, H. Anal. Biochem. 2009, 392, 103-109
37. Kielar, F.; Congreve, A.; Law, G. L.; New, E. J.; Parker, D.; Wong, K. L.; Castreňo, P.; de Mendoza, J. Chem. Commun. 2008, 21, 2435-2437
38. Li, G.; Ferrie, A. M.; Fang, Y. J. Assoc. Lab. Autom. 2006, 11, 181-187
39. Schnabel, P.; Maack, C.; Mies, F.; Tyroller, S.; Scheer, A.; Böhm, M. J. Cardiovasc. Pharmacol. 2000, 36, 466-471
40. Hoffmann, C.; Leitz, M. R.; Oberdorf-Maass, S.; Lohse, M. J.; Klotz, K. N. Naunyn-Schmiedeberg's Arch. Pharmacol. 2004, 369, 151-159
41. Smith, C.; Teitler, M. Cardiovasc. Drugs Ther. 1999, 13, 123-126
42. Brixius, K.; Bundkirchen, A.; Bölck, B.; Mehlhorn, U.; Schwinger, R. H. Br. J. Pharmacol. 2001, 133, 1330-1338
43. Leitz, A. J.; Bayburt, T. H.; Barnakov, A. N.; Springer, B. A.; Sligar, S. G. BioTechniques 2006, 40, 601-602, 604, 606, ff.