Agonist-selective mechanisms of GPCR desensitization

British Journal of Pharmacology

Volumn 153, Issue SUPPL. 1, 2008, Pages

  Kelly, E ^a   Bailey, C P ^a,b   Henderson, G ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b University of Bath   (United Kingdom)

Author keywords

Desensitization; Functional selectivity; GPCR; GRK; MOPr; PKA; PKC; Second messenger dependent protein kinase

Indexed keywords

APAFANT; BETA 2 ADRENERGIC RECEPTOR; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR KINASE; GUANINE NUCLEOTIDE BINDING PROTEIN; METENKEPHALIN; MORPHINE; MU OPIATE RECEPTOR; PROTEIN KINASE C; RETINA S ANTIGEN;

AGONIST; BIOLOGICAL ACTIVITY; CONFERENCE PAPER; HUMAN; MEDIATOR; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; RECEPTOR DOWN REGULATION; REGULATORY MECHANISM; SECOND MESSENGER;

ANIMALS; HUMANS; PROTEIN KINASES; RECEPTORS, G-PROTEIN-COUPLED; SECOND MESSENGER SYSTEMS;

EID: 40349114499     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/sj.bjp.0707604     Document Type: Conference Paper

References (87)