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Volumn 40, Issue 5, 2006, Pages 601-612

Functional reconstitution of β2-adrenergic receptors utilizing self-assembling Nanodisc technology

Author keywords

[No Author keywords available]

Indexed keywords

CELL MEMBRANES; FUNCTIONAL ANALYSIS; IMAGE RECOGNITION; PHOSPHOLIPIDS; PROTEINS; SCAFFOLDS;

EID: 33745511381     PISSN: 07366205     EISSN: None     Source Type: Journal    
DOI: 10.2144/000112169     Document Type: Article
Times cited : (186)

References (35)
  • 1
    • 0037024360 scopus 로고    scopus 로고
    • Identification of G protein-coupled receptor genes from the human genome sequence
    • Takeda, S., S. Kadowaki, T. Haga, H. Takaesu, and S. Mitaku. 2002. Identification of G protein-coupled receptor genes from the human genome sequence. FEBS Lett. 520:97-101.
    • (2002) FEBS Lett , vol.520 , pp. 97-101
    • Takeda, S.1    Kadowaki, S.2    Haga, T.3    Takaesu, H.4    Mitaku, S.5
  • 2
    • 0000140263 scopus 로고    scopus 로고
    • Novel GPCRs and their endogenous ligands: Expanding the boundaries of physiology and pharmacology
    • Marchese, A., S.R. George, L.F. Kolakowski, Jr., K.R. Lynch, and B.F. O'Dowd. 1999. Novel GPCRs and their endogenous ligands: expanding the boundaries of physiology and pharmacology. Trends Pharmacol. Sci. 20:370-375.
    • (1999) Trends Pharmacol. Sci , vol.20 , pp. 370-375
    • Marchese, A.1    George, S.R.2    Kolakowski Jr., L.F.3    Lynch, K.R.4    O'Dowd, B.F.5
  • 3
    • 0036669944 scopus 로고    scopus 로고
    • Strategies to identify ligands for orphan G-protein-coupled receptors
    • Milligan, G. 2002. Strategies to identify ligands for orphan G-protein-coupled receptors. Biochem. Soc. Trans. 30:789-793.
    • (2002) Biochem. Soc. Trans , vol.30 , pp. 789-793
    • Milligan, G.1
  • 5
    • 0036174608 scopus 로고    scopus 로고
    • Dimerization: An emerging concept for G protein-coupled receptor ontogeny and function
    • Angers, S., A. Salahpour, and M. Bouvier. 2002. Dimerization: an emerging concept for G protein-coupled receptor ontogeny and function. Annu. Rev. Pharmacol. Toxicol. 42:409-435.
    • (2002) Annu. Rev. Pharmacol. Toxicol , vol.42 , pp. 409-435
    • Angers, S.1    Salahpour, A.2    Bouvier, M.3
  • 6
    • 0037224730 scopus 로고    scopus 로고
    • Biochemical characterization of beta2-adrenergic receptor dimers and oligomers
    • Salahpour, A., H. Bonin, S. Bhalla, U. Petaja-Repo, and M. Bouvier. 2003. Biochemical characterization of beta2-adrenergic receptor dimers and oligomers. Biol. Chem. 384:117-123.
    • (2003) Biol. Chem , vol.384 , pp. 117-123
    • Salahpour, A.1    Bonin, H.2    Bhalla, S.3    Petaja-Repo, U.4    Bouvier, M.5
  • 7
    • 0021160160 scopus 로고
    • The mammalian beta 2-adrenergic receptor: Purification and characterization
    • Benovic, J.L., R.G. Shorr, M.G. Caron, and R.J. Lefkowitz. 1984. The mammalian beta 2-adrenergic receptor: purification and characterization. Biochemistrv 23:4510-4518.
    • (1984) Biochemistrv , vol.23 , pp. 4510-4518
    • Benovic, J.L.1    Shorr, R.G.2    Caron, M.G.3    Lefkowitz, R.J.4
  • 8
    • 0026524038 scopus 로고
    • Solubilization of dopamine D-1 receptors with a zwitterionic detergent DCHAPS and their reconstitution
    • Soskic, V. and J. Joksimovic. 1992. Solubilization of dopamine D-1 receptors with a zwitterionic detergent DCHAPS and their reconstitution. Int J. Biochem. 24:585-591.
    • (1992) Int J. Biochem , vol.24 , pp. 585-591
    • Soskic, V.1    Joksimovic, J.2
  • 9
    • 0027214607 scopus 로고
    • Differential solubilization of membrane lipids by detergents: Coenrichment of the sheep brain serotonin 5-HT1A receptor with phc spholipids containing predominantly saturated fatty acids
    • Banerjee, P., A. Dasgupta, B.A. Chromy, and G. Dawson. 1993. Differential solubilization of membrane lipids by detergents: coenrichment of the sheep brain serotonin 5-HT1A receptor with phc spholipids containing predominantly saturated fatty acids. Arch. Biochem. Biophys. 305:68-77.
    • (1993) Arch. Biochem. Biophys , vol.305 , pp. 68-77
    • Banerjee, P.1    Dasgupta, A.2    Chromy, B.A.3    Dawson, G.4
  • 10
    • 0025824974 scopus 로고
    • Binding of alpha- and beta gamma-subunits of Go to beta 1-adrenoceptor in sealed unilamellar lipid vesicles
    • Kurstjens, N.P., M. Frohlich, C. Dees, R.C. Cantrill, M. Hekman, and E.J. Helmreich. 1991. Binding of alpha- and beta gamma-subunits of Go to beta 1-adrenoceptor in sealed unilamellar lipid vesicles. Eur. J. Biochem. 197:167-176.
    • (1991) Eur. J. Biochem , vol.197 , pp. 167-176
    • Kurstjens, N.P.1    Frohlich, M.2    Dees, C.3    Cantrill, R.C.4    Hekman, M.5    Helmreich, E.J.6
  • 11
    • 0027218190 scopus 로고
    • Reconstitution of a purified mu-opioid binding protein in liposomes: Selective, high affinity, GTP gamma S-sensitive mu-opioid agonist binding is restored
    • Gioannini, T.L., L.Q. Fan, L. Hyde, D. Ofri, Y.H. Yao, J.M. Hiller, and E.J. Simon. 1993. Reconstitution of a purified mu-opioid binding protein in liposomes: selective, high affinity, GTP gamma S-sensitive mu-opioid agonist binding is restored. Biochem. Biophys. Res. Commun. 194:901-908.
    • (1993) Biochem. Biophys. Res. Commun , vol.194 , pp. 901-908
    • Gioannini, T.L.1    Fan, L.Q.2    Hyde, L.3    Ofri, D.4    Yao, Y.H.5    Hiller, J.M.6    Simon, E.J.7
  • 13
    • 0037160105 scopus 로고    scopus 로고
    • Quantitative assessment of beta 1- and beta 2-adrenergic receptor homo- and heterodimerization by bioluminescence resonance energy transfer
    • Mercier, J.F., A. Salahpour, S. Angers, A. Breit, and M. Bouvier. 2002. Quantitative assessment of beta 1- and beta 2-adrenergic receptor homo- and heterodimerization by bioluminescence resonance energy transfer. J. Biol. Chem. 277:44925-44931.
    • (2002) J. Biol. Chem , vol.277 , pp. 44925-44931
    • Mercier, J.F.1    Salahpour, A.2    Angers, S.3    Breit, A.4    Bouvier, M.5
  • 14
    • 0042351113 scopus 로고    scopus 로고
    • Expression of L-CCR in HEK 293 cells reveals functional responses to CCL2, CCL5, CCL7, and CCL8
    • Biber, K., M.W. Zuurman, H. Homan, and H.W. Boddeke. 2003. Expression of L-CCR in HEK 293 cells reveals functional responses to CCL2, CCL5, CCL7, and CCL8. J. Leukoc. Biol. 74:243-251.
    • (2003) J. Leukoc. Biol , vol.74 , pp. 243-251
    • Biber, K.1    Zuurman, M.W.2    Homan, H.3    Boddeke, H.W.4
  • 15
    • 0037864223 scopus 로고    scopus 로고
    • Pharmacological analysis of a dopamine D(2Short):G(alphao) fusion protein expressed in Sf9 cells
    • Gazi, L., T. Wurch, J.F. Lopez-Gimenez, P.J. Pauwels, and P.G. Strange. 2003. Pharmacological analysis of a dopamine D(2Short):G(alphao) fusion protein expressed in Sf9 cells. FEES Lett. 545:155-160.
    • (2003) FEES Lett , vol.545 , pp. 155-160
    • Gazi, L.1    Wurch, T.2    Lopez-Gimenez, J.F.3    Pauwels, P.J.4    Strange, P.G.5
  • 17
    • 0040130142 scopus 로고    scopus 로고
    • Cloning, functional expression and characterization of a human olfactory receptor
    • Hatt, H., G. Gisselmann, and C.H. Wetzel. 1999. Cloning, functional expression and characterization of a human olfactory receptor. Cell. Mol. Biol. (Noisy-le-grand) 45:285-291.
    • (1999) Cell. Mol. Biol. (Noisy-le-grand) , vol.45 , pp. 285-291
    • Hatt, H.1    Gisselmann, G.2    Wetzel, C.H.3
  • 18
    • 0003083826 scopus 로고
    • cDNA for the human beta 2-adrenergic receptor: A protein with multiple membrane-spanning domains and encoded by a gene whose chromosomal location is shared with that of the receptor for platelet-derived growth factor
    • Kobilka, B.K., R.A. Dixon, T. Frielle, H.G. Dohlman, M.A. Bolanowski, I.S. Sigal, T.L. Yang-Feng, U. Francke, et al. 1987. cDNA for the human beta 2-adrenergic receptor: a protein with multiple membrane-spanning domains and encoded by a gene whose chromosomal location is shared with that of the receptor for platelet-derived growth factor. Proc. Natl. Acad. Sci. USA 84:46-50.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 46-50
    • Kobilka, B.K.1    Dixon, R.A.2    Frielle, T.3    Dohlman, H.G.4    Bolanowski, M.A.5    Sigal, I.S.6    Yang-Feng, T.L.7    Francke, U.8
  • 19
    • 0021193681 scopus 로고
    • The mammalian beta 2-adrenergic receptor: Reconstitution of functional interactions between pure receptor and pure stimulatory nucleotide binding protein of the adenylate cyclase system
    • Cerione, R.A., J. Codina, J.L. Benovic, R.J. Lefkowitz, L. Birnbaumer, and M.G. Caron. 1984. The mammalian beta 2-adrenergic receptor: reconstitution of functional interactions between pure receptor and pure stimulatory nucleotide binding protein of the adenylate cyclase system. Biochemistry 23:4519-4525.
    • (1984) Biochemistry , vol.23 , pp. 4519-4525
    • Cerione, R.A.1    Codina, J.2    Benovic, J.L.3    Lefkowitz, R.J.4    Birnbaumer, L.5    Caron, M.G.6
  • 20
    • 0023656689 scopus 로고
    • Functional activity and regulation of human beta 2-adrenergic receptors expressed in Xenopus oocytes
    • Kobilka, B.K., C. MacGregor, K. Daniel, T.S. Kobilka, M.G. Caron, and R.J. Lefkowitz. 1987. Functional activity and regulation of human beta 2-adrenergic receptors expressed in Xenopus oocytes. J. Biol. Chem. 262:15796-15802.
    • (1987) J. Biol. Chem , vol.262 , pp. 15796-15802
    • Kobilka, B.K.1    MacGregor, C.2    Daniel, K.3    Kobilka, T.S.4    Caron, M.G.5    Lefkowitz, R.J.6
  • 21
    • 0036950335 scopus 로고    scopus 로고
    • Agonist-induced conformational changes in the beta2 adrenergic receptor
    • Kobilka, B.K. 2002. Agonist-induced conformational changes in the beta2 adrenergic receptor. J. Pept. Res. 60:317-321.
    • (2002) J. Pept. Res , vol.60 , pp. 317-321
    • Kobilka, B.K.1
  • 22
    • 0345791508 scopus 로고    scopus 로고
    • Sequential binding of agonists to the beta2 adrenoceptor. Kinetic evidence for intermediate conformational states
    • Swaminath, G., Y. Xiang, T.W. Lee, J. Steenhuis, C. Parnot, and B.K. Kobilka. 2004. Sequential binding of agonists to the beta2 adrenoceptor. Kinetic evidence for intermediate conformational states. J. Biol. Chem. 279:686-691.
    • (2004) J. Biol. Chem , vol.279 , pp. 686-691
    • Swaminath, G.1    Xiang, Y.2    Lee, T.W.3    Steenhuis, J.4    Parnot, C.5    Kobilka, B.K.6
  • 23
    • 0033794067 scopus 로고    scopus 로고
    • Molecular analysis of beta(2)-adrenoceptor coupling to G(s)-, G(i)-, and G(q)-proteins
    • Wenzel-Seifert, K. and R. Seifert. 2000. Molecular analysis of beta(2)-adrenoceptor coupling to G(s)-, G(i)-, and G(q)-proteins. Mol. Pharmacol. 58:954-966.
    • (2000) Mol. Pharmacol , vol.58 , pp. 954-966
    • Wenzel-Seifert, K.1    Seifert, R.2
  • 24
    • 0026319547 scopus 로고
    • Selectivity of the beta-adrenergic receptor among Gs, Gi's, and Go: Assay using recombinant alpha subunits in reconstituted phospholipid vesicles
    • Rubenstein, R.C., M.E. Linder, E.M. Ross, Z.D. Guo, H. Suga, M. Okamura, S. Takeda, T. Haga, et al. 1991. Selectivity of the beta-adrenergic receptor among Gs, Gi's, and Go: assay using recombinant alpha subunits in reconstituted phospholipid vesicles. Biochemistry 30:10769-10777.
    • (1991) Biochemistry , vol.30 , pp. 10769-10777
    • Rubenstein, R.C.1    Linder, M.E.2    Ross, E.M.3    Guo, Z.D.4    Suga, H.5    Okamura, M.6    Takeda, S.7    Haga, T.8
  • 25
    • 0142179052 scopus 로고    scopus 로고
    • Self-assembly of single integral membrane proteins into soluble nanoscale phospholipid bilayers
    • Bayburt, T.H. and S.G Sligar. 2003. Self-assembly of single integral membrane proteins into soluble nanoscale phospholipid bilayers. Protein Sci. 12:2476-2481.
    • (2003) Protein Sci , vol.12 , pp. 2476-2481
    • Bayburt, T.H.1    Sligar, S.G.2
  • 26
    • 1642382983 scopus 로고    scopus 로고
    • Directed self-assembly of monodisperse phospholipid bilayer Nanodiscs with controlled size
    • Denisov, I.G., Y.V. Grinkova, A.A. Lazarides, and S.G. Sligar. 2004. Directed self-assembly of monodisperse phospholipid bilayer Nanodiscs with controlled size. J. Am. Chem. Soc. 126:3477-3487.
    • (2004) J. Am. Chem. Soc , vol.126 , pp. 3477-3487
    • Denisov, I.G.1    Grinkova, Y.V.2    Lazarides, A.A.3    Sligar, S.G.4
  • 27
    • 4444297536 scopus 로고    scopus 로고
    • Homotropic cooperativity of monomeric cytochrome P450 3A4 in a nanoscale native bilayer environment
    • Baas, B.J., I.G. Denisov, and S.G. Sligar. 2004. Homotropic cooperativity of monomeric cytochrome P450 3A4 in a nanoscale native bilayer environment. Arch. Biochem. Biophys. 430:218-228.
    • (2004) Arch. Biochem. Biophys , vol.430 , pp. 218-228
    • Baas, B.J.1    Denisov, I.G.2    Sligar, S.G.3
  • 28
    • 0042691480 scopus 로고    scopus 로고
    • Direct solubilization of heterologously expressed membrane proteins by incorporation into nanoscale lipid bilayers
    • Civjan, N.R., T.H. Bayburt, M.A. Schuler, and S.G. Sligar. 2003. Direct solubilization of heterologously expressed membrane proteins by incorporation into nanoscale lipid bilayers. BioTechniques 35:556-563.
    • (2003) BioTechniques , vol.35 , pp. 556-563
    • Civjan, N.R.1    Bayburt, T.H.2    Schuler, M.A.3    Sligar, S.G.4
  • 29
    • 0043007514 scopus 로고    scopus 로고
    • Self-assembly of discoidal phospholipid bilayer nanoparticles with membrane scaffold proteins
    • Bayburt, T.H., Y.V. Grinkova, and S.G. Sligar. 2002. Self-assembly of discoidal phospholipid bilayer nanoparticles with membrane scaffold proteins. Nano Lett. 2:853-856.
    • (2002) Nano Lett , vol.2 , pp. 853-856
    • Bayburt, T.H.1    Grinkova, Y.V.2    Sligar, S.G.3
  • 30
    • 0015861774 scopus 로고
    • Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction
    • Cheng, Y. and W.H. Prusoff. 1973. Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction. Biochem. Pharmacol. 22:3099-3108.
    • (1973) Biochem. Pharmacol , vol.22 , pp. 3099-3108
    • Cheng, Y.1    Prusoff, W.H.2
  • 31
    • 0018198945 scopus 로고
    • +/-)-[3H]Epinephrine and (-)[3H]dihydroalprenolol binding to beta1-and beta2-noradrenergic receptors in brain, heart, and lung membranes
    • U'Prichard, D.C., D.B. Bylund, and S.H. Snyder. 1978. (+/-)-[3H]Epinephrine and (-)[3H]dihydroalprenolol binding to beta1-and beta2-noradrenergic receptors in brain, heart, and lung membranes. J. Biol. Chem. 253:5090-5102.
    • (1978) J. Biol. Chem , vol.253 , pp. 5090-5102
    • U'Prichard, D.C.1    Bylund, D.B.2    Snyder, S.H.3
  • 32
    • 0017099834 scopus 로고
    • Structure-activity relationships of adenylate cyclase-coupled beta adrenergic receptors: Determination by direct binding studies
    • Mukherjee, C., M.G. Caron, D. Mullikin, and R.J. Lefkowitz. 1976. Structure-activity relationships of adenylate cyclase-coupled beta adrenergic receptors: determination by direct binding studies. Mol. Pharmacol. 12:16-31.
    • (1976) Mol. Pharmacol , vol.12 , pp. 16-31
    • Mukherjee, C.1    Caron, M.G.2    Mullikin, D.3    Lefkowitz, R.J.4
  • 33
    • 0023864252 scopus 로고
    • Expression of a human cDNA encoding the beta 2-adrenergic receptor in Chinese hamster fibroblasts (CHW): Functionality and regulation of the expressed receptors
    • Bouvier, M., M. Hnatowich, S. Collins, B.K. Kobilka, A. Deblasi, R.J. Lefkowitz, and M.G. Caron. 1988. Expression of a human cDNA encoding the beta 2-adrenergic receptor in Chinese hamster fibroblasts (CHW): functionality and regulation of the expressed receptors. Mol. Pharmacol. 33:133-139.
    • (1988) Mol. Pharmacol , vol.33 , pp. 133-139
    • Bouvier, M.1    Hnatowich, M.2    Collins, S.3    Kobilka, B.K.4    Deblasi, A.5    Lefkowitz, R.J.6    Caron, M.G.7
  • 34
    • 0025837077 scopus 로고
    • Reconstitution of receptor/GTP-binding protein interactions
    • Cerione, R.A. 1991. Reconstitution of receptor/GTP-binding protein interactions. Biochim. Biophys. Acta 1071:473-501.
    • (1991) Biochim. Biophys. Acta , vol.1071 , pp. 473-501
    • Cerione, R.A.1
  • 35
    • 0021712818 scopus 로고
    • Catecholamine-stimulated guanosine 5′-O-(3-thiotriphosphate) binding to the stimulatory GTP-binding protein of adenylate cyclase: Kinetic analysis in reconstituted phospholipid vesicles
    • Asano, T. and E.M. Ross. 1984. Catecholamine-stimulated guanosine 5′-O-(3-thiotriphosphate) binding to the stimulatory GTP-binding protein of adenylate cyclase: kinetic analysis in reconstituted phospholipid vesicles. Biochemistry 23:5467-5471.
    • (1984) Biochemistry , vol.23 , pp. 5467-5471
    • Asano, T.1    Ross, E.M.2


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