A mathematical model of the unfolded protein stress response reveals the decision mechanism for recovery, adaptation and apoptosis

BMC Systems Biology

Volumn 7, Issue , 2013, Pages

  Erguler, Kamil ^a   Pieri, Myrtani ^a   Deltas, Constantinos ^a  

^a UNIVERSITY OF CYPRUS   (Cyprus)

Author keywords

Bifurcation; Chaperones; Endoplasmic reticulum stress; Mathematical modelling; Oscillation; Sensitivity; Translation attenuation; Unfolded protein response

Indexed keywords

ANIMALIA; METAZOA;

ACTIVATING TRANSCRIPTION FACTOR 6; APOPTOSIS REGULATORY PROTEIN; PERK KINASE; PROTEIN KINASE R;

ADAPTATION; APOPTOSIS; ARTICLE; BIOLOGICAL MODEL; ENDOPLASMIC RETICULUM STRESS; KINETICS; METABOLISM; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; UNFOLDED PROTEIN RESPONSE;

ACTIVATING TRANSCRIPTION FACTOR 6; ADAPTATION, PHYSIOLOGICAL; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; EIF-2 KINASE; ENDOPLASMIC RETICULUM STRESS; KINETICS; MODELS, BIOLOGICAL; PROTEIN BIOSYNTHESIS; RECEPTOR CROSS-TALK; SIGNAL TRANSDUCTION; UNFOLDED PROTEIN RESPONSE;

EID: 84874010654     PISSN: None     EISSN: 17520509     Source Type: Journal    
DOI: 10.1186/1752-0509-7-16     Document Type: Article

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