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Volumn , Issue , 2005, Pages 334-357

Computer Modeling in the Study of Aging

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EID: 84873991116     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-012088387-5/50015-7     Document Type: Chapter
Times cited : (4)

References (123)
  • 1
    • 0028996001 scopus 로고
    • Optimality theory, Gompertz' law, and the disposable soma theory of senescence
    • Abrams P.A., Ludwig D. Optimality theory, Gompertz' law, and the disposable soma theory of senescence. Evolution 1995, 49:1055-1066.
    • (1995) Evolution , vol.49 , pp. 1055-1066
    • Abrams, P.A.1    Ludwig, D.2
  • 4
    • 0142122844 scopus 로고    scopus 로고
    • Growth, telomere dynamics and successful and unsuccessful human aging
    • Aviv A., Levy D., Mangel M. Growth, telomere dynamics and successful and unsuccessful human aging. Mechanisms of Ageing & Development 2003, 124:829-837.
    • (2003) Mechanisms of Ageing & Development , vol.124 , pp. 829-837
    • Aviv, A.1    Levy, D.2    Mangel, M.3
  • 6
    • 0029668371 scopus 로고    scopus 로고
    • Heuristic optimization of the general life history problem: a novel approach
    • Blarer A., Doebeli M. Heuristic optimization of the general life history problem: a novel approach. Evolutionary Ecology 1996, 10:81-96.
    • (1996) Evolutionary Ecology , vol.10 , pp. 81-96
    • Blarer, A.1    Doebeli, M.2
  • 8
    • 0031885843 scopus 로고    scopus 로고
    • Role of mitochondrial DNA mutations in human aging: implications for the central nervous system and muscle
    • Brierley E.J., Johnson M.A., Lightowlers R.N., James O.F.W., Turnbull D.M. Role of mitochondrial DNA mutations in human aging: implications for the central nervous system and muscle. Annals of Neurology 1998, 43:217-223.
    • (1998) Annals of Neurology , vol.43 , pp. 217-223
    • Brierley, E.J.1    Johnson, M.A.2    Lightowlers, R.N.3    James, O.F.W.4    Turnbull, D.M.5
  • 9
    • 0035820667 scopus 로고    scopus 로고
    • Patterns of age-specific means and genetic variances of mortality rates predicted by the mutation-accumulation theory of ageing
    • Charlesworth B. Patterns of age-specific means and genetic variances of mortality rates predicted by the mutation-accumulation theory of ageing. Journal of Theoretical Biology 2001, 210:47-65.
    • (2001) Journal of Theoretical Biology , vol.210 , pp. 47-65
    • Charlesworth, B.1
  • 10
    • 0033358580 scopus 로고    scopus 로고
    • Relaxed replication of mtDNA: a model with implications for the expression of disease
    • Chinnery P.F., Samuels D.C. Relaxed replication of mtDNA: a model with implications for the expression of disease. American Journal of Human Genetics 1999, 64:1158-1165.
    • (1999) American Journal of Human Genetics , vol.64 , pp. 1158-1165
    • Chinnery, P.F.1    Samuels, D.C.2
  • 11
  • 15
    • 77049158727 scopus 로고
    • The population consequences of life history phenomena
    • Cole L.C. The population consequences of life history phenomena. Quarterly Review of Biology 1954, 29:103-137.
    • (1954) Quarterly Review of Biology , vol.29 , pp. 103-137
    • Cole, L.C.1
  • 17
    • 0001957349 scopus 로고    scopus 로고
    • Bayes linear strategies for matching hydrocarbon reservoir history
    • Oxford Science Publications, Oxford, A.F.M. Smith (Ed.)
    • Craig P.S., Goldstein M., Seheult A.H., Smith J.A. Bayes linear strategies for matching hydrocarbon reservoir history. Bayesian statistics 5 1996, 69-95. Oxford Science Publications, Oxford. A.F.M. Smith (Ed.).
    • (1996) Bayesian statistics 5 , pp. 69-95
    • Craig, P.S.1    Goldstein, M.2    Seheult, A.H.3    Smith, J.A.4
  • 18
    • 84950437532 scopus 로고
    • Bayesian prediction of deterministic functions, with applications to the design and analysis of computer experiments
    • Currin C., Mitchell T., Morris M., Ylvisaker D. Bayesian prediction of deterministic functions, with applications to the design and analysis of computer experiments. Journal of the American Statistical Association 1991, 86:953-963.
    • (1991) Journal of the American Statistical Association , vol.86 , pp. 953-963
    • Currin, C.1    Mitchell, T.2    Morris, M.3    Ylvisaker, D.4
  • 19
    • 0031081410 scopus 로고    scopus 로고
    • A proposed refinement of the mitochondrial free radical theory of aging
    • de Grey A.D.N.J. A proposed refinement of the mitochondrial free radical theory of aging. BioEssays 1997, 19:161-166.
    • (1997) BioEssays , vol.19 , pp. 161-166
    • de Grey, A.D.N.J.1
  • 22
    • 1942444653 scopus 로고    scopus 로고
    • Modeling senescence in hypotrichous ciliates
    • Duerr H.P., Eichner M., Ammermann D. Modeling senescence in hypotrichous ciliates. Protist 2004, 155:45-52.
    • (2004) Protist , vol.155 , pp. 45-52
    • Duerr, H.P.1    Eichner, M.2    Ammermann, D.3
  • 23
    • 0035097502 scopus 로고    scopus 로고
    • Random intracellular drift explains the clonal expansion of mitochondrial DNA mutations with age
    • Elson J.L., Samuels D.C., Turnbull D.M., Chinnery P.F. Random intracellular drift explains the clonal expansion of mitochondrial DNA mutations with age. American Journal of Human Genetics 2001, 68:802-806.
    • (2001) American Journal of Human Genetics , vol.68 , pp. 802-806
    • Elson, J.L.1    Samuels, D.C.2    Turnbull, D.M.3    Chinnery, P.F.4
  • 24
    • 0027064693 scopus 로고
    • Accelerated disappearance of ovarian follicles in midlife: implications for forecasting menopause
    • Faddy M.J., Gosden R.G., Gougeon A., Richardson S.J., Nelson J.F. Accelerated disappearance of ovarian follicles in midlife: implications for forecasting menopause. Human Reproduction 1992, 7:1342-1346.
    • (1992) Human Reproduction , vol.7 , pp. 1342-1346
    • Faddy, M.J.1    Gosden, R.G.2    Gougeon, A.3    Richardson, S.J.4    Nelson, J.F.5
  • 25
    • 0031928002 scopus 로고    scopus 로고
    • Variations in senescence and longevity include the possibility of negligible senescence
    • Finch C.E. Variations in senescence and longevity include the possibility of negligible senescence. Journals of Gerontology A: Biological Sciences 1998, 53:B235-B239.
    • (1998) Journals of Gerontology A: Biological Sciences , vol.53
    • Finch, C.E.1
  • 28
    • 9444266171 scopus 로고    scopus 로고
    • CellDesigner: a process diagram editor for gene-regulatory and biochemical networks
    • Funahashi A., Tanimura N., Morohashi M., Kitano H. CellDesigner: a process diagram editor for gene-regulatory and biochemical networks. Biosilico 2003, 1:159-162.
    • (2003) Biosilico , vol.1 , pp. 159-162
    • Funahashi, A.1    Tanimura, N.2    Morohashi, M.3    Kitano, H.4
  • 31
    • 0031713548 scopus 로고    scopus 로고
    • A dynamic model of proliferation and differentiation in the intestinal crypt based on a hypothetical intraepithelial growth factor
    • Gerike T.G., Paulus U., Potten C.S., Loeffler M. A dynamic model of proliferation and differentiation in the intestinal crypt based on a hypothetical intraepithelial growth factor. Cell Proliferation 1998, 31:93-110.
    • (1998) Cell Proliferation , vol.31 , pp. 93-110
    • Gerike, T.G.1    Paulus, U.2    Potten, C.S.3    Loeffler, M.4
  • 32
    • 0041377721 scopus 로고    scopus 로고
    • Likelihood estimation for stochastic compartmental models using Markov chain methods
    • Gibson G.J., Renshaw E. Likelihood estimation for stochastic compartmental models using Markov chain methods. Statistics & Computing 2001, 11:347-358.
    • (2001) Statistics & Computing , vol.11 , pp. 347-358
    • Gibson, G.J.1    Renshaw, E.2
  • 34
    • 27744503232 scopus 로고    scopus 로고
    • Bayesian inference for stochastic kinetic models using a diffusion approximation
    • Golightly A., Wilkinson D.J. Bayesian inference for stochastic kinetic models using a diffusion approximation. Biometrics 2005, 61:781-788.
    • (2005) Biometrics , vol.61 , pp. 781-788
    • Golightly, A.1    Wilkinson, D.J.2
  • 35
    • 3442887390 scopus 로고    scopus 로고
    • Does Makeham make sense?
    • Golubev A. Does Makeham make sense?. Biogerontology 2004, 5:159-167.
    • (2004) Biogerontology , vol.5 , pp. 159-167
    • Golubev, A.1
  • 36
    • 0142217926 scopus 로고    scopus 로고
    • An in silico investigation into the causes of telomere length heterogeneity and its implications for the Hayflick limit
    • Golubev A., Khrustalev S., Butov A. An in silico investigation into the causes of telomere length heterogeneity and its implications for the Hayflick limit. Journal of Theoretical Biology 2003, 225:153-170.
    • (2003) Journal of Theoretical Biology , vol.225 , pp. 153-170
    • Golubev, A.1    Khrustalev, S.2    Butov, A.3
  • 37
    • 0013942563 scopus 로고
    • The moulding of senescence by natural selection
    • Hamilton W.D. The moulding of senescence by natural selection. Journal of Theoretical Biology 1966, 12:12-45.
    • (1966) Journal of Theoretical Biology , vol.12 , pp. 12-45
    • Hamilton, W.D.1
  • 38
    • 0036083675 scopus 로고    scopus 로고
    • The generation of long telomere overhangs in human cells: a model and its implication
    • Hao Y.H., Tan Z. The generation of long telomere overhangs in human cells: a model and its implication. Bioinformatics 2002, 18:666-671.
    • (2002) Bioinformatics , vol.18 , pp. 666-671
    • Hao, Y.H.1    Tan, Z.2
  • 39
    • 77049308856 scopus 로고
    • A theory based on free radical and radiation chemistry
    • Harman D. A theory based on free radical and radiation chemistry. Journal of Gerontology 1956, 11:298-300.
    • (1956) Journal of Gerontology , vol.11 , pp. 298-300
    • Harman, D.1
  • 42
    • 84896253373 scopus 로고
    • Schattaner Verlag, Stuttgart, H. Bredt, J.W. Rohen (Eds.)
    • Hayflick L. Ageing and Development 1972, Vol. 4:1-15. Schattaner Verlag, Stuttgart. H. Bredt, J.W. Rohen (Eds.).
    • (1972) Ageing and Development , vol.4 , pp. 1-15
    • Hayflick, L.1
  • 45
    • 16244389030 scopus 로고    scopus 로고
    • Markov chain Monte Carlo-based approaches for inference in computationally intensive inverse problems
    • Oxford Science Publications, Oxford, M. West (Ed.)
    • Higdon D., Lee H., Holloman C. Markov chain Monte Carlo-based approaches for inference in computationally intensive inverse problems. Bayesian Statistics 2003, 7:181-197. Oxford Science Publications, Oxford. M. West (Ed.).
    • (2003) Bayesian Statistics , vol.7 , pp. 181-197
    • Higdon, D.1    Lee, H.2    Holloman, C.3
  • 47
    • 0019778446 scopus 로고
    • Predictions of the somatic mutation and mortlization theories of cellular aging are contrary to experimental-observations
    • Holliday R., Kirkwood T.B.L. Predictions of the somatic mutation and mortlization theories of cellular aging are contrary to experimental-observations. Journal of Theoretical Biology 1981, 93:627-642.
    • (1981) Journal of Theoretical Biology , vol.93 , pp. 627-642
    • Holliday, R.1    Kirkwood, T.B.L.2
  • 50
    • 0037342537 scopus 로고    scopus 로고
    • The Systems Biology Markup Language (SBML): a medium for representation and exchange of biochemical network models
    • Hucka M., Finney A., Sauro H.M., Bolouri H., Doyle J.C., Kitano H. The Systems Biology Markup Language (SBML): a medium for representation and exchange of biochemical network models. Bioinformatics 2003, 19:524-531.
    • (2003) Bioinformatics , vol.19 , pp. 524-531
    • Hucka, M.1    Finney, A.2    Sauro, H.M.3    Bolouri, H.4    Doyle, J.C.5    Kitano, H.6
  • 51
    • 0033788296 scopus 로고    scopus 로고
    • Metabolic mechanisms of yeast ageing
    • Jazwinski S.M. Metabolic mechanisms of yeast ageing. Experimental Gerontology 2000, 35:671-676.
    • (2000) Experimental Gerontology , vol.35 , pp. 671-676
    • Jazwinski, S.M.1
  • 52
    • 0025004091 scopus 로고
    • Increased life span of age-1 mutants in caenorhabditis elegans and lower Gompertz rate of aging
    • Jahnson T.E. Increased life span of age-1 mutants in caenorhabditis elegans and lower Gompertz rate of aging. Science 1990, 249:908-912.
    • (1990) Science , vol.249 , pp. 908-912
    • Jahnson, T.E.1
  • 54
    • 0017782437 scopus 로고
    • Evolution of ageing
    • Kirkwood T.B.L. Evolution of ageing. Nature 1977, 270:301-304.
    • (1977) Nature , vol.270 , pp. 301-304
    • Kirkwood, T.B.L.1
  • 56
    • 0037167844 scopus 로고    scopus 로고
    • The old worm turns more slowly
    • Kirkwood T.B.L., Finch C.E. The old worm turns more slowly. Nature 2002, 419:794-795.
    • (2002) Nature , vol.419 , pp. 794-795
    • Kirkwood, T.B.L.1    Finch, C.E.2
  • 57
    • 0016836493 scopus 로고
    • Commitment to senescence: a model for the finite and infinite growth of diploid and tranformed human fibroblasts in culture
    • Kirkwood T.B.L., Holliday R. Commitment to senescence: a model for the finite and infinite growth of diploid and tranformed human fibroblasts in culture. Journal of Theoretical Biology 1975, 53:481-496.
    • (1975) Journal of Theoretical Biology , vol.53 , pp. 481-496
    • Kirkwood, T.B.L.1    Holliday, R.2
  • 61
    • 0028271046 scopus 로고
    • Towards a network theory of ageing: a model combining the free radical theory and the protein error theory
    • Kowald A., Kirkwood T.B.L. Towards a network theory of ageing: a model combining the free radical theory and the protein error theory. Journal of Theoretical Biology 1994, 168:75-94.
    • (1994) Journal of Theoretical Biology , vol.168 , pp. 75-94
    • Kowald, A.1    Kirkwood, T.B.L.2
  • 62
    • 0029890534 scopus 로고    scopus 로고
    • A network theory of ageing: the interactions of defective mitochondria, aberrant proteins, free radicals and scavengers in the aging process
    • Kowald A., Kirkwood T.B.L. A network theory of ageing: the interactions of defective mitochondria, aberrant proteins, free radicals and scavengers in the aging process. Mutation Research-DNAging Genetic Instability and Aging 1996, 316:209-236.
    • (1996) Mutation Research-DNAging Genetic Instability and Aging , vol.316 , pp. 209-236
    • Kowald, A.1    Kirkwood, T.B.L.2
  • 63
    • 0034695436 scopus 로고    scopus 로고
    • Accumulation of defective mitochondria through delayed degradation of damaged organelles and its possible role in the ageing of post-mitotic and dividing cells
    • Kowald A., Kirkwood T.B.L. Accumulation of defective mitochondria through delayed degradation of damaged organelles and its possible role in the ageing of post-mitotic and dividing cells. Journal of Theoretical Biology 2000, 202:145-160.
    • (2000) Journal of Theoretical Biology , vol.202 , pp. 145-160
    • Kowald, A.1    Kirkwood, T.B.L.2
  • 64
    • 3242675827 scopus 로고    scopus 로고
    • Automated reverse engineering of metabolic pathways from observed data by means of genetic programming
    • MIT Press, Cambridge, MA, H. Kitano (Ed.)
    • Koza J.R., Mydlowec W., Lanza G., Yu J., Keane M.A. Automated reverse engineering of metabolic pathways from observed data by means of genetic programming. Foundations of systems biology 2001, 95-121. MIT Press, Cambridge, MA. H. Kitano (Ed.).
    • (2001) Foundations of systems biology , pp. 95-121
    • Koza, J.R.1    Mydlowec, W.2    Lanza, G.3    Yu, J.4    Keane, M.A.5
  • 66
    • 16644361888 scopus 로고    scopus 로고
    • A calculus of purpose
    • Lander A.D. A calculus of purpose. Plos Biology 2004, 2:712-714.
    • (2004) Plos Biology , vol.2 , pp. 712-714
    • Lander, A.D.1
  • 67
    • 0034977077 scopus 로고    scopus 로고
    • Aking the age-old questions
    • Larsen P.L. Aking the age-old questions. Nature Genetics 2001, 28:102-104.
    • (2001) Nature Genetics , vol.28 , pp. 102-104
    • Larsen, P.L.1
  • 68
    • 0028349234 scopus 로고
    • Differential accumulation of 4977 bp deletion in mitochondrial DNA of various tissuues in human ageing
    • Lee C.M., Pang C.Y., Hsu H.S., Wei Y.H. Differential accumulation of 4977 bp deletion in mitochondrial DNA of various tissuues in human ageing. Biochemica Et Biophysica Acta 1994, 1226:37-43.
    • (1994) Biochemica Et Biophysica Acta , vol.1226 , pp. 37-43
    • Lee, C.M.1    Pang, C.Y.2    Hsu, H.S.3    Wei, Y.H.4
  • 69
    • 0042631525 scopus 로고    scopus 로고
    • Rethinking the volutionary theory of aging: transfers, not births, shape social species
    • Lee R.D. Rethinking the volutionary theory of aging: transfers, not births, shape social species. Proceedings of the National Academy of Sciences of the USa 2003, 100:9637-9642.
    • (2003) Proceedings of the National Academy of Sciences of the USa , vol.100 , pp. 9637-9642
    • Lee, R.D.1
  • 71
    • 0013526704 scopus 로고
    • Shortening of life and causes of death in mice exposed to single whole-body dose of radiation
    • Lindop P.J., Rotblat J. Shortening of life and causes of death in mice exposed to single whole-body dose of radiation. Nature 1961, 189:645-648.
    • (1961) Nature , vol.189 , pp. 645-648
    • Lindop, P.J.1    Rotblat, J.2
  • 72
    • 0032086674 scopus 로고    scopus 로고
    • Aging mechanisms from nematodes to mammals
    • Lithgow G.J. Aging mechanisms from nematodes to mammals. Nutrition 1998, 14:522-524.
    • (1998) Nutrition , vol.14 , pp. 522-524
    • Lithgow, G.J.1
  • 74
    • 0027318112 scopus 로고
    • Somatic mutation, monoclonality and stochastic-models of stem-cell organization in the intestinal crypt
    • Loeffler M., Birke A., Winton D., Potten C. Somatic mutation, monoclonality and stochastic-models of stem-cell organization in the intestinal crypt. Journal of Theoretical Biology 1993, 160:471-491.
    • (1993) Journal of Theoretical Biology , vol.160 , pp. 471-491
    • Loeffler, M.1    Birke, A.2    Winton, D.3    Potten, C.4
  • 77
    • 2442424215 scopus 로고    scopus 로고
    • The shape of things to come: using models with physiological structure to predict mortality trajectories
    • Mangel M., Bonsall M.B. The shape of things to come: using models with physiological structure to predict mortality trajectories. Theoretical Population Biology 2004, 65:353-359.
    • (2004) Theoretical Population Biology , vol.65 , pp. 353-359
    • Mangel, M.1    Bonsall, M.B.2
  • 79
    • 0031715965 scopus 로고    scopus 로고
    • Altered stem cell regeneration in irradiated intestinal crypts of sene scent mice
    • Martin K., Potten C.S., Roberts S.A., Kirkwood T.B.L. Altered stem cell regeneration in irradiated intestinal crypts of sene scent mice. Journal of Cell Science 1998, 111:2297-2303.
    • (1998) Journal of Cell Science , vol.111 , pp. 2297-2303
    • Martin, K.1    Potten, C.S.2    Roberts, S.A.3    Kirkwood, T.B.L.4
  • 81
    • 0034902642 scopus 로고    scopus 로고
    • Cell migration and organization in the intestinal crypt using a lattice-free model
    • Meineke F.A., Potten C.S., Loeffler M. Cell migration and organization in the intestinal crypt using a lattice-free model. Cell Proliferation 2001, 34:253-266.
    • (2001) Cell Proliferation , vol.34 , pp. 253-266
    • Meineke, F.A.1    Potten, C.S.2    Loeffler, M.3
  • 84
    • 0027525966 scopus 로고
    • Different in situ hybridization patterns of mitochondrial DNA in cytochrome c oxidase-deficient extraocular muscle fibres in the elderly
    • Müller-Höcker J., Seibel P., Schneiderbanger K., Kadenbach B. Different in situ hybridization patterns of mitochondrial DNA in cytochrome c oxidase-deficient extraocular muscle fibres in the elderly. Virchows Arch (A) 1993, 422:7-15.
    • (1993) Virchows Arch (A) , vol.422 , pp. 7-15
    • Müller-Höcker, J.1    Seibel, P.2    Schneiderbanger, K.3    Kadenbach, B.4
  • 85
    • 0031722063 scopus 로고    scopus 로고
    • Declining fecundity and ovarian ageing in natural fertility populations
    • O'Connor K.A., Holman D.J., Wood J.W. Declining fecundity and ovarian ageing in natural fertility populations. Maturitas 1998, 30:127-136.
    • (1998) Maturitas , vol.30 , pp. 127-136
    • O'Connor, K.A.1    Holman, D.J.2    Wood, J.W.3
  • 87
    • 0032937038 scopus 로고    scopus 로고
    • Stochastic models of telomere shortening
    • Olofsson P., Kimmel M. Stochastic models of telomere shortening. Mathematical Biosciences 1999, 158:75-92.
    • (1999) Mathematical Biosciences , vol.158 , pp. 75-92
    • Olofsson, P.1    Kimmel, M.2
  • 88
    • 0036847164 scopus 로고    scopus 로고
    • A tutorial introduction to Bayesian inference for stochastic epidemic models using Markov chain Monte Carlo Methods
    • O'Neill P.D. A tutorial introduction to Bayesian inference for stochastic epidemic models using Markov chain Monte Carlo Methods. Mathematical Biosciences 2002, 180:103-114.
    • (2002) Mathematical Biosciences , vol.180 , pp. 103-114
    • O'Neill, P.D.1
  • 89
    • 0025662627 scopus 로고
    • Optimality Theory in Evolutionary Biology
    • Parker G.A., Smith J.M. Optimality Theory in Evolutionary Biology. Nature 1990, 348:27-33.
    • (1990) Nature , vol.348 , pp. 27-33
    • Parker, G.A.1    Smith, J.M.2
  • 90
    • 0028801625 scopus 로고
    • A hypothesis for the origin and evolution of menopause
    • Peccei J.S. A hypothesis for the origin and evolution of menopause. Maturitas 1995, 21:83-89.
    • (1995) Maturitas , vol.21 , pp. 83-89
    • Peccei, J.S.1
  • 91
    • 0031946737 scopus 로고    scopus 로고
    • Mortality plateaus and the evolution of senescence: Why are old-age mortality rates so low?
    • Pletcher S.D., Curtsinger J.W. Mortality plateaus and the evolution of senescence: Why are old-age mortality rates so low?. Evolution 1998, 52:454-464.
    • (1998) Evolution , vol.52 , pp. 454-464
    • Pletcher, S.D.1    Curtsinger, J.W.2
  • 92
    • 0036139411 scopus 로고    scopus 로고
    • Modelling telomere shortening and the role of oxidative stress
    • Proctor C.J., Kirkwood T.B.L. Modelling telomere shortening and the role of oxidative stress. Mechaism of Ageing & Develoment 2002, 123:351-363.
    • (2002) Mechaism of Ageing & Develoment , vol.123 , pp. 351-363
    • Proctor, C.J.1    Kirkwood, T.B.L.2
  • 93
    • 0141670453 scopus 로고    scopus 로고
    • Modelling cellular senescence as a result of telomere state
    • Proctor C.J., Kirkwood T.B.L. Modelling cellular senescence as a result of telomere state. Aging Cell 2003, 2:151-157.
    • (2003) Aging Cell , vol.2 , pp. 151-157
    • Proctor, C.J.1    Kirkwood, T.B.L.2
  • 97
    • 0037396198 scopus 로고    scopus 로고
    • Age related changes in population of peripheral T cells: towards a model of immunosenescence
    • Romanyukha A.A., Yashin A.I. Age related changes in population of peripheral T cells: towards a model of immunosenescence. Mechanisms of Ageing & Development 2003, 124:433-443.
    • (2003) Mechanisms of Ageing & Development , vol.124 , pp. 433-443
    • Romanyukha, A.A.1    Yashin, A.I.2
  • 98
    • 0033590952 scopus 로고    scopus 로고
    • Stochastic mechanism of cellular aging: abrupt telomere shortening as a model for, stochastic nature of cellular aging
    • Rubelj I., Vondracek Z. Stochastic mechanism of cellular aging: abrupt telomere shortening as a model for, stochastic nature of cellular aging. Journal of Theoretical Biology 1999, 197:425-438.
    • (1999) Journal of Theoretical Biology , vol.197 , pp. 425-438
    • Rubelj, I.1    Vondracek, Z.2
  • 100
    • 0021033943 scopus 로고
    • The application of optimal control theory to the general life history problem
    • Schaffer W.M. The application of optimal control theory to the general life history problem. American Naturalist 1983, 121:418-431.
    • (1983) American Naturalist , vol.121 , pp. 418-431
    • Schaffer, W.M.1
  • 101
    • 0036480049 scopus 로고    scopus 로고
    • The effects of kin on child mortality in rural Gambia
    • Sear R., Steele F., McGregor A.A., Mace R. The effects of kin on child mortality in rural Gambia. Demography 2002, 39:43-63.
    • (2002) Demography , vol.39 , pp. 43-63
    • Sear, R.1    Steele, F.2    McGregor, A.A.3    Mace, R.4
  • 102
    • 0033910956 scopus 로고    scopus 로고
    • Calorie restriction and aging: a life-history analysis
    • Shanley D.P., Kirkwood T.B.L. Calorie restriction and aging: a life-history analysis. Evolution 2000, 54:740-750.
    • (2000) Evolution , vol.54 , pp. 740-750
    • Shanley, D.P.1    Kirkwood, T.B.L.2
  • 103
    • 0035112192 scopus 로고    scopus 로고
    • Evolution of the human menopause
    • Shanley D.P., Kirkwood T.B.L. Evolution of the human menopause. Bioessays 2001, 23:282-287.
    • (2001) Bioessays , vol.23 , pp. 282-287
    • Shanley, D.P.1    Kirkwood, T.B.L.2
  • 105
    • 0037198057 scopus 로고    scopus 로고
    • Paradigms and pitfalls of yeast longevity research
    • Sinclair D.A. Paradigms and pitfalls of yeast longevity research. Mechanisms of Ageing & Development 2002, 123:857-867.
    • (2002) Mechanisms of Ageing & Development , vol.123 , pp. 857-867
    • Sinclair, D.A.1
  • 106
    • 0035930836 scopus 로고    scopus 로고
    • A stochastic model of cell replicative senescence based on telomere shortening, oxidative stress, and somatic mutations in nuclear and mitochondrial DNA
    • Sozou P.D., Kirkwood T.B.L. A stochastic model of cell replicative senescence based on telomere shortening, oxidative stress, and somatic mutations in nuclear and mitochondrial DNA. Journal of Theoretical Biology 2001, 213:573-586.
    • (2001) Journal of Theoretical Biology , vol.213 , pp. 573-586
    • Sozou, P.D.1    Kirkwood, T.B.L.2
  • 110
    • 0033591198 scopus 로고    scopus 로고
    • Intramitotic and intraclonal variation in proliferative potential of human diploid cells: Explained by telomere shortening
    • Tan Z. Intramitotic and intraclonal variation in proliferative potential of human diploid cells: Explained by telomere shortening. Journal of Theoretical Biology 1999, 198:259-268.
    • (1999) Journal of Theoretical Biology , vol.198 , pp. 259-268
    • Tan, Z.1
  • 111
    • 0032713323 scopus 로고    scopus 로고
    • Telomere shortening and the population size-dependency of life span of human cell culture: further implication for two proliferation-restricting telomeres
    • Tan Z. Telomere shortening and the population size-dependency of life span of human cell culture: further implication for two proliferation-restricting telomeres. Experimental Gerontology 1999, 34:831-842.
    • (1999) Experimental Gerontology , vol.34 , pp. 831-842
    • Tan, Z.1
  • 112
    • 0035201811 scopus 로고    scopus 로고
    • Simulated shortening of proliferation-restricting telomeres during clonal proliferation and senescence of human cells
    • Tan Z. Simulated shortening of proliferation-restricting telomeres during clonal proliferation and senescence of human cells. Experimental Gerontology 2001, 36:89-97.
    • (2001) Experimental Gerontology , vol.36 , pp. 89-97
    • Tan, Z.1
  • 114
    • 0031971990 scopus 로고    scopus 로고
    • Evolutionary optimal age schedule of repair: computer modelling of energy partition between current and future survival and reproduction
    • Teriokhin A.T. Evolutionary optimal age schedule of repair: computer modelling of energy partition between current and future survival and reproduction. Evolutionary Ecology 1998, 12:291-307.
    • (1998) Evolutionary Ecology , vol.12 , pp. 291-307
    • Teriokhin, A.T.1
  • 115
    • 0036948006 scopus 로고    scopus 로고
    • A mathematical model that accounts for the effects of caloric restriction on body weight and longevity
    • van Leeuwen I.M.M., Kelpin F.D.L., Koojiman S. A mathematical model that accounts for the effects of caloric restriction on body weight and longevity. Biogerontology 2002, 3:373-381.
    • (2002) Biogerontology , vol.3 , pp. 373-381
    • van Leeuwen, I.M.M.1    Kelpin, F.D.L.2    Koojiman, S.3
  • 118
    • 0034644270 scopus 로고    scopus 로고
    • The segment polarity network is a robust developmental module
    • von Dassow G., Meir E., Munro E.M., Odell G.M. The segment polarity network is a robust developmental module. Nature 2000, 406:188-192.
    • (2000) Nature , vol.406 , pp. 188-192
    • von Dassow, G.1    Meir, E.2    Munro, E.M.3    Odell, G.M.4
  • 119
    • 0033954684 scopus 로고    scopus 로고
    • Accumulation of single-strand breaks is the major cause of telomere shortening in human fibroblasts
    • von Zglinicki T., Pilger R., Sitte N. Accumulation of single-strand breaks is the major cause of telomere shortening in human fibroblasts. Free Radical Biology & Medicine 2000, 28:64-74.
    • (2000) Free Radical Biology & Medicine , vol.28 , pp. 64-74
    • von Zglinicki, T.1    Pilger, R.2    Sitte, N.3
  • 120
    • 0029127226 scopus 로고
    • Mild hyperoxia shortens telomeres and inhibits proliferation of fibroblasts: a model for senescence
    • von Zglinicki T., Saretzki G., Docke W., Lotze C. Mild hyperoxia shortens telomeres and inhibits proliferation of fibroblasts: a model for senescence. Experimental Cell Research 1995, 220:186-193.
    • (1995) Experimental Cell Research , vol.220 , pp. 186-193
    • von Zglinicki, T.1    Saretzki, G.2    Docke, W.3    Lotze, C.4
  • 121
    • 0348155848 scopus 로고    scopus 로고
    • Petri net technology for communication-based systems: Advances in Petri nets
    • Springer-Verlag, Heidelberg, H. Weber (Ed.)
    • Weber M., Kindler E. Petri net technology for communication-based systems: Advances in Petri nets. The Petri Net Markup Language 2003, 124-144. Springer-Verlag, Heidelberg. H. Weber (Ed.).
    • (2003) The Petri Net Markup Language , pp. 124-144
    • Weber, M.1    Kindler, E.2
  • 122
    • 0032585574 scopus 로고    scopus 로고
    • Human longevity at the cost of reproductive success
    • Westendorp R.G.J., Kirkwood T.B.L. Human longevity at the cost of reproductive success. Nature 1998, 396:743-746.
    • (1998) Nature , vol.396 , pp. 743-746
    • Westendorp, R.G.J.1    Kirkwood, T.B.L.2
  • 123
    • 0000055057 scopus 로고
    • Pleiotropy, natural selection, and the evolution of senescence
    • Williams G.C. Pleiotropy, natural selection, and the evolution of senescence. Evolution 1957, 11.
    • (1957) Evolution , vol.11
    • Williams, G.C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.