Modelling the actions of chaperones and their role in ageing

Mechanisms of Ageing and Development

Volumn 126, Issue 1, 2005, Pages 119-131

  Proctor, Carole J ^a   Soti, Csaba ^b   Boys, Richard J ^a   Gillespie, Colin S ^a   Shanley, Daryl P ^a   Wilkinson, Darren J ^a   Kirkwood, Thomas B L ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b SEMMELWEIS UNIVERSITY   (Hungary)

Author keywords

Ageing; Chaperones; Mathematical model; Stress response

Indexed keywords

CHAPERONE; HEAT SHOCK PROTEIN;

AGING; ALZHEIMER DISEASE; APOPTOSIS; CATARACT; CONFERENCE PAPER; IMMUNE RESPONSE; MATHEMATICAL MODEL; MOLECULAR DYNAMICS; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DENATURATION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS; PROTEOMICS; STRESS;

ANIMALS; CELL AGING; DNA-BINDING PROTEINS; HEAT-SHOCK RESPONSE; HUMANS; MICE; MODELS, BIOLOGICAL; MOLECULAR CHAPERONES; PROTEIN FOLDING; RATS; TRANSCRIPTION FACTORS;

EID: 10944269121     PISSN: 00476374     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mad.2004.09.031     Document Type: Conference Paper

References (27)

1. F.W. Booth, and J.O. Holloszy Cytochrome c turnover in rat skeletal muscles J. Biol. Chem. 252 1977 416 419
2. P. Csermely, T. Schnaider, C. Söti, Z. Prohaszka, and G. Nardai The 90 kDa molecular chaperone family: structure, function, and clinical applications. A comprehensive review Pharmacol. Ther. 79 1998 129 168
3. M.A. Gibson, and J. Bruck Efficient exact stochastic simulation of chemical systems with many species and many channels J. Phys. Chem. A 104 2000 1876 1889
4. D.T. Gillespie Approximate accelerated stochastic simulation of chemically reacting systems J. Chem. Phys. 115 2001 1716 1733
5. J.R. Glover, and S. Lindquist Hspl04, Hsp70, and Hsp40: a novel chaperone system that rescues previously aggregated proteins Cell 94 1998 73 82
6. A.R. Heydari, S. You, R. Takahashi, A. Gutsmann-Conrad, K.D. Sarge, and A. Richardson Age-related alterations in the activation of heat shock transcription factor 1 in rat hepatocytes Exp. Cell Res. 256 2000 83 93
7. M. Hucka, A. Finney, H.M. Sauro, H. Bolouri, J.C. Doyle, H. Kitano and the rest of the SBML Forum: Arkin, A.P., Bornstein, B.J., Bray, D., Cornish-Bowden, A., Cuellar, A.A., Dronov, S., Gilles, E.D., Ginkel, M., Gor, V., Goryanin, I.I., Hedley, W.J., Hodgman, T.C., Hofmeyr, J.-H., Hunter, P.J., Juty, N.S., Kasberger, J.L., Kremling, A., Kummer, U., Le Novere, N., Loew, L.M., Lucio, D., Mendes, P., Minch, E., Mjolsness, E.D., Nakayama, Y., Nelson, M.R., Nielsen, P.F., Sakurada, T., Schaff, J.C., Shapiro, B.E., Shimizu, T.S., Spence, H.D., Stelling, J., Takahashi, K., Tomita, M., Wagner, J., Wang, J. The systems biology markup language (SBML): a medium for representation and exchange of biochemical network models Bioinformatics 19 2003 524 531
8. U. Jakob, and J. Buchner Assisting spontaneity: the role of Hsp90 and small Hsps as molecular chaperones Trends Biochem. Sci. 19 1994 205 211
9. U. Jakob, H. Lilie, I. Meyer, and J. Buchner Transient interaction of Hsp90 with early unfolding intermediates of citrate synthase J. Biol. Chem. 270 1995 7288 7294
10. K. Kawanaka, I. Tabata, S. Katsuta, and M. Higuchi Changes in insulin-stimulated glucose transport and GLUT-4 protein in rat skeletal muscle after training J. Appl. Physiol. 83 1997 2043 2047
11. T.B.L. Kirkwood, R.J. Boys, C.S. Gillespie, C.J. Proctor, D.P. Shanley, and D.J. Wilkinson Towards an e-biology of ageing: integrating theory and data Nat. Rev. Mol. Cell Biol. 4 2003 243 249
12. K.C. Kregel Heat shock proteins: modifying factors in physiological stress responses and acquired thermotolerance J. Appl. Physiol. 92 2002 2177 2186
13. H. Lodish, A. Berk, S.L. Zipursky, P. Matsudaira, D. Baltimore, and J. Darnell Molecular Cell Biology 2000 W.H. Freeman and Company New York
14. A. Mathew, and R.I. Morimoto Role of the heat-shock response in the life and death of proteins P. Csermely Stress of Life: From Molecules to Man vol. 851 1998 Ann. N. Y. Acad. Sci. pp. 99-111
15. R.I. Morimoto Regulation of the heat shock transcriptional response: cross talk between a family of heat shock factors, molecular chaperones, and negative regulators Genes Dev. 12 1998 3788 3796
16. K. Nadeau, A. Das, and C. Walsh Hsp90 chaperonins possess ATPase activity and bind heat shock transcription factors and peptidyl prolyl isomerases J. Biol. Chem. 268 1993 1479 1487
17. J. Nylandsted, M. Rohde, K. Brand, L. Bastholm, F. Elling, and M. Jaattela Selective depletion of heat shock protein 70 (Hsp70) activates a tumor-specific death program that is independent of caspases and bypasses Bcl-2 Proc. Natl. Acad. Sci. U.S.A. 97 2000 7871 7876
18. J. Puchalka, and A.M. Kierzek Bridging the gap between stochastic and deterministic regimes in the kinetic simulations of the biochemical reaction networks Biophys. J. 86 2004 1357 1372
19. Punyiczki, M., Fesus, L., 1998. CT heat shock and apoptosis - the two defense systems of the organism may have overlapping molecular elements. In: Csermely, P. (Ed.), Stress of Life: From Molecules to Man. Ann. N. Y. Acad. Sci., vol. 851, pp. 67-74.
20. A. Samali, and S. Orrenius Heat shock proteins: regulators of stress response and apoptosis Cell Stress Chaperones 3 1998 228 236
21. C. Soti, and P. Csermely Molecular chaperones and the aging process Biogerontology 1 2000 225 233
22. C. Soti, and P. Csermely Aging and molecular chaperones Exp. Gerontol. 38 2003 1037 1040
23. C. Soti, A.S. Sreedhar, and P. Csermely Apoptosis, necrosis and cellular senescence: chaperone occupancy as a potential switch Aging Cell 2 2003 39 45
24. A.S. Sreedhar, K. Mihaly, B. Pato, T. Schnaider, A. Stetak, K. Kis-Petik, J. Fidy, T. Simonics, A. Maraz, and P. Csermely Hsp90 inhibition accelerates cell lysis: anti-Hsp90 ribozyme reveals a complex mechanism of Hsp90 inhibitors involving both superoxide- and Hsp90-dependent events J. Biol. Chem. 278 2003 35231 35240
25. P. Verbeke, J. Fonager, B.F.C. Clark, and S.I.S. Rattan Heat shock response and ageing: mechanisms and applications Cell Biol. Int. 25 2001 845 857
26. S. Wickner, M.R. Maurizi, and S. Gottesman Posttranslational quality control: folding, refolding, and degrading proteins Science 286 1999 1888 1893
27. J. Zou, Y. Guo, T. Guettouche, D.F. Smith, and R. Voellmy Repression of heat shock transcription factor HSF1 activation by HSP90 (HSP90 complex) that forms a stress-sensitive complex with HSF1 Cell 94 1998 471 480