Electrospray ionization-induced protein unfolding

Journal of the American Society for Mass Spectrometry

Volumn 23, Issue 12, 2012, Pages 2122-2131

  Lin, Hong ^a   Kitova, Elena N ^a   Johnson, Margaret A ^a   Eugenio, Luiz ^b   Ng, Kenneth K S ^b   Klassen, John S ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b UNIVERSITY OF CALGARY   (Canada)

Author keywords

Charging mechanism; Electrospray ionization; Protein unfolding

Indexed keywords

CHARGE STATE DISTRIBUTION; CHARGING MECHANISM; DICHROISM SPECTROSCOPY; ELECTROSPRAY IONIZATION MASS SPECTROMETRY; GEL-FILTRATION CHROMATOGRAPHY; NEUTRAL AQUEOUS SOLUTION; PROTEIN UNFOLDING; PROTON NUCLEAR MAGNETIC RESONANCE;

CIRCULAR DICHROISM SPECTROSCOPY; ELECTRIC CHARGE; ELECTROSPRAY IONIZATION; GEL PERMEATION CHROMATOGRAPHY; MASS SPECTROMETRY; NEGATIVE IONS; PROTEINS;

IONIC STRENGTH;

AMMONIUM ACETATE; CLOSTRIDIUM DIFFICILE TOXIN B; ION; MUTANT PROTEIN; ACETIC ACID DERIVATIVE; BACTERIAL PROTEIN; BACTERIAL TOXIN; PROTEIN; RECOMBINANT PROTEIN; TOXB PROTEIN, CLOSTRIDIUM DIFFICILE;

AMINO ACID SEQUENCE; ANALYTICAL EQUIPMENT; AQUEOUS SOLUTION; ARTICLE; CARBOXY TERMINAL SEQUENCE; CHEMICAL REACTION; CIRCULAR DICHROISM; COMPUTER PROGRAM; CONTROLLED STUDY; COULOMBIC REPULSION; ELECTROSPRAY MASS SPECTROMETRY; GEL FILTRATION CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IONIC STRENGTH; LIQUID; MASS SPECTROMETER; NONHUMAN; PH; PROTEIN FOLDING; PROTEIN UNFOLDING; PROTON NUCLEAR MAGNETIC RESONANCE; SURFACE CHARGE; CHEMICAL STRUCTURE; CHEMISTRY; GEL CHROMATOGRAPHY; GENETICS; METABOLISM; METHODOLOGY; MUTATION; NUCLEAR MAGNETIC RESONANCE;

CLOSTRIDIUM DIFFICILE;

ACETATES; BACTERIAL PROTEINS; BACTERIAL TOXINS; CHROMATOGRAPHY, GEL; CIRCULAR DICHROISM; HYDROGEN-ION CONCENTRATION; MODELS, MOLECULAR; MUTATION; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN UNFOLDING; PROTEINS; RECOMBINANT PROTEINS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 84873962867     PISSN: 10440305     EISSN: 18791123     Source Type: Journal    
DOI: 10.1007/s13361-012-0483-y     Document Type: Article

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