Vapor treatment of electrospray droplets: Evidence for the folding of initially denatured proteins on the sub-millisecond time-scale

Journal of the American Society for Mass Spectrometry

Volumn 23, Issue 1, 2012, Pages 88-101

  Kharlamova, Anastasia ^a   Demuth, J Corinne ^a   McLuckey, Scott A ^a  

^a PURDUE UNIVERSITY   (United States)

Author keywords

Charge state distributions; Nano electrospray ionization; Protein conformations

Indexed keywords

ACIDIC VAPORS; BASIC SOLUTIONS; BIMODAL DISTRIBUTION; CHARGE STATE; CHARGE STATE DISTRIBUTION; CHARGED DROPLET; COUNTER CURRENT; CYTOCHROME C; DENATURED PROTEINS; ELECTROSPRAY DROPLETS; INITIAL SOLUTION; MODEL SYSTEM; NATIVE PROTEINS; PH CHANGE; PROTEIN CONFORMATIONS; SOLUTION PH; TIME-SCALES; UBIQUITIN;

CARBONIC ANHYDRASE; DROPS; ELECTROSPRAY IONIZATION; IONIZATION OF GASES; MASS SPECTROMETRY; VAPORS;

PROTEINS;

CARBONATE DEHYDRATASE; CYTOCHROME C; MYOGLOBIN; REAGENT; UBIQUITIN;

ARTICLE; CHEMICAL PROCEDURES; CONTROLLED STUDY; COUNTERCURRENT SYSTEM; ELECTROPRAY DROPLET; ELECTROSPRAY; GAS; MASS SPECTROMETER; MASS SPECTROMETRY; PH; PKA; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN FOLDING; PROTEIN LOCALIZATION; SAMPLING; SURFACE CHARGE; TIME; VAPOR TREATMENT;

ACETIC ACID; ANIMALS; CATTLE; GASES; HUMANS; HYDROGEN-ION CONCENTRATION; PIPERIDINES; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN REFOLDING; PROTEINS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; STATIC ELECTRICITY;

EID: 84856144689     PISSN: 10440305     EISSN: 18791123     Source Type: Journal    
DOI: 10.1007/s13361-011-0258-x     Document Type: Article

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