Quantifying protein-fatty acid interactions using electrospray ionization mass spectrometry

Journal of the American Society for Mass Spectrometry

Volumn 22, Issue 2, 2011, Pages 310-318

  Liu, Lan ^a   Kitova, Elena N ^a   Klassen, John S ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Affinity; Electrospray ionization mass spectrometry; Fatty acids; Lactoglobulin; Protein ligand complexes

Indexed keywords

AFFINITY; ASSOCIATION CONSTANT; CAPRIC ACID; CAPRYLIC ACID; COMPETITIVE FLUORESCENCE; ELECTROSPRAY IONIZATION MASS SPECTROMETRY; FLUORESCENCE MEASUREMENTS; GAS PHASE IONS; HIGH CONCENTRATION; LACTOGLOBULIN; LAURIC ACID; MYRISTIC ACID; NO BINDING; OPTIMAL SAMPLING; POSITIVE ION MODE; PROTEIN-LIGAND COMPLEXES; PROTONATED; RELATIVE ABUNDANCE; SAMPLING CONDITIONS; SOLUTION ADDITIVES;

ASSOCIATION REACTIONS; COMPLEXATION; DISSOCIATION; FLUORESCENCE; ION SOURCES; IONIZATION OF GASES; LIGANDS; MASS SPECTROMETRY; NEGATIVE IONS; PALMITIC ACID; PROTEINS; PROTONATION; SATURATED FATTY ACIDS; STEARIC ACID;

ELECTROSPRAY IONIZATION;

BETA LACTOGLOBULIN; FATTY ACID DERIVATIVE; HEXANOIC ACID; IMIDAZOLE; LAURIC ACID; MYRISTIC ACID; OCTANOIC ACID; PALMITIC ACID;

ARTICLE; CHEMICAL REACTION KINETICS; CONCENTRATION (PARAMETERS); DISSOCIATION; ELECTROSPRAY MASS SPECTROMETRY; FLUORESCENCE ANALYSIS; GAS; LIPID ANALYSIS; PROTEIN ANALYSIS; PROTEIN LIPID INTERACTION; PROTON TRANSPORT;

ACETATES; ALGORITHMS; ANIMALS; CATTLE; FATTY ACIDS; HYDROGEN-ION CONCENTRATION; LACTOGLOBULINS; PROTEIN BINDING; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

BOVINAE;

EID: 79952511159     PISSN: 10440305     EISSN: 18791123     Source Type: Journal    
DOI: 10.1007/s13361-010-0032-5     Document Type: Article

References (26)

1. Daniel, J.M., Friess, S.D., Rajagopalan, S., Wendt, S., Zenobi, R.: Quantitative determination of noncovalent binding interactions using soft ionization mass spectrometry. Int. J. Mass Spectrom. 216, 1-27 (2002)
2. Schug, K.A.: Solution phase enantioselective recognition and discrimination by electrospray ionization-mass spectrometry: State-of-the-Art methods and an eye towards increased throughput measurements. Comb. Chem. High Throughput Screen. 10, 301-316 (2007)
3. Heck, A.J.R., Van Den Heuvel, R.H.H.: Investigation of intact protein complexes by mass spectrometry. Mass Spectrom. Rev. 23, 368-389 (2004)
4. Wang, W., Kitova, E.N., Klassen, J.S.: Influence of solution and gas phase processes on protein-carbohydrate binding affinities determined by nanoelectrospray Fourier-transform ion cyclotron resonance mass spectrometry. Anal. Chem. 75, 4945-4955 (2003)
5. Shoemaker, G.K., Soya, N., Palcic, M.M., Klassen, J.S.: Temperature-dependent cooperativity in donor-accepator substrate binding to the human blood group glycosltransferases. Glycobiology 18, 587-592 (2008)
6. Soya, N., Shoemaker, G.K., Palcic, M.M., Klassen, J.S.: Comparative study of substrate and product binding to the human ABO(H) blood group glycosyltransferases. Glycobiology 19, 1224-1234 (2009)
7. Rademacher, C., Shoemaker, G.K., Kim, H.-S., Zheng, R.B., Taha, H., Liu, C., Nacario, R.C., Schriemer, D.C., Klassen, J.S., Peters, T., Lowary, T.L.: Ligand specificity of CS-35, a monoclonal antibody that recognizes mycobacterial lipoarabinomannan. A model system for oligofuranoside-protein recognition. J. Am. Chem. Soc. 129, 10489-10502 (2007)
8. Jorgensen, T.J.D., Roepstorff, P., Heck, A.J.R.: Direct determination of solution binding constants for noncovalent complexes between bacterial cell wall peptide analogues and vancomycin group antibiotics by electrospray ionization mass spectrometry. Anal. Chem. 70, 4427-4432 (1998)
9. Jecklin, M.C., Touboul, D., Bovet, C., Wortmann, A., Zenobi, R.: Which electrospray-based ionization method best reflects protein-ligand interactions found in solution? A comparison of ESI, nanoESI, and ESSI for the determination of dissociation constants with mass spectrometry. J. Am. Soc. Mass Spectrom. 19, 332-343 (2008)
10. Yu, Y.H., Kirkup, C.E., Pi, N., Leary, J.A.: Characterization of noncovalent protein-ligand complexes and associated enzyme intermediates of GlcNAc-6-O-sulfotransferase by electrospray ionization FTICR mass spectrometry. J. Am. Soc. Mass Spectrom. 15, 1400-1407 (2004)
11. Robinson, C.V., Chung, E.W., Kragelund, B.B., Knudsen, J., Aplin, R. T., Poulsen, F.M., Dobson, C.M.: Probing the nature of noncovalent interactions by mass spectrometry. A study of protein-CoA ligand binding and assembly. J. Am. Chem. Soc. 118, 8646-8653 (1996)
12. Yin, S., Xie, Y., Loo, J.A.: Mass spectrometry of protein-ligand complexes: Enhanced gas-phase stability of ribonuclease-nucleotide complexes. J. Am. Soc. Mass Spectrom. 19, 1199-1208 (2008)
13. Stanley, W.A., Versluis, K., Schultz, C., Heck, A.J.R., Wilmanns, M.: Investigation of the ligand spectrum of human sterol carrier protein 2 using a direct mass spectrometry assay. Arch. Biochem. Biophys. 461, 50-58 (2007)
14. Hooper, A.M.; Dufour, S.; He, X.; Muck, A.; Zhou, J.; Almeida, R.; Field, L.M.; Svatos, A.; Pickett, J.A. High-throughput ESI-MS analysis of binding between the Bombyx mori pheromone-binding protein BmorPBP1, its pheromone components, and some analogues. Chem. Commun. 5725-5727 (2009)
15. Clark, S.M., Konermann, L.: Determination of ligand-protein dissociation constants by electrospray mass spectrometry-based diffusion measurements. Anal. Chem. 76, 7077-7083 (2004)
16. Van Dongen, W.D., Heck, A.J.R.: Binding of selected carbohydrates to apo-concanavalin a studied by electrospray ionization mass spectrometry. Analyst 125, 583-589 (2000)
17. Sun, J., Kitova, E.N., Klassen, J.S.: Method for stabilizing protein- ligand complexes in nanoelectrospray ionization mass spectrometry. Anal. Chem. 79, 416-425 (2007)
18. Bagal, D., Kitova, E.N., Liu, L., El-Haweit, A., Schnier, P.D., Klassen, J.S.: Gas phase stabilization of noncovalent protein complexes formed by electrospray ionization. Anal. Chem. 81, 7801-7806 (2009)
19. Kontopidis, G., Holt, C., Sawyer, L.: Beta-lactoglobulin: Binding properties, structure, and function. J. Dairy Sci. 87, 785-796 (2004)
20. Qin, B.Y., Bewley, M.C., Creamer, L.K., Baker, H.M., Baker, E.N., Jameson, G.B.: Structural basis of the tanford transition of bovine β- lactoglobulin. Biochemistry 37, 14014-14023 (1998)
21. Collini, M., D'Alfonso, L., Molinari, H., Ragona, L., Catalaono, M., Baldini, G.: Competitive binding of fatty acids and the fluorescent probe 1-8-anilinonaphthalene sulfonate to bovine β-lactoglobulin. Protein Sci. 12, 1596-1603 (2003)
22. El-Hawiet, A., Kitova, E.N., Liu, L., Klassen, J.S.: Quantifying labile protein-ligand interactions using electrospray ionization mass spectrometry. J. Am. Soc. Mass Spectrom. 21, 1893-1899 (2010)
23. Wu, S.-Y., Perez, M.D., Puyol, P., Sawyer, L.: β-lactoglobulin binds palmitate within its central cavity. J. Biol. Chem. 274, 170-174 (1999)
24. Hunter, E.P., Lias, S.G.: Evaluated gas phase basicities and proton affinities of molecules: An update. J. Phys. Chem. Ref. Data 27, 413-656 (1998)
25. Kitova, E.N., Seo, M., Roy, P.N., Klassen, J.S.: Elucidating the intermolecular interactions within a desolvated protein-ligand complex. An experimental and computational study. J. Am. Chem. Soc. 130, 1214-1226 (2008)
26. Liu, L., Bagal, D., Kitova, E.N., Schnier, P.D., Klassen, J.S.: Hydrophobic protein-ligand interactions preserved in the gas phase. J. Am. Chem. Soc. 131, 15980-15981 (2009)