메뉴 건너뛰기




Volumn 12, Issue 4, 2011, Pages 286-294

Expression of CD4 + forkhead box P3 (FOXP3) + regulatory T cells in inflammatory bowel disease

Author keywords

FOXP3 protein; Immunohistochemistry; Inflammatory bowel disease; Regulatory T lymphocyte

Indexed keywords

CD4 ANTIGEN; MESSENGER RNA; PROTEIN; TRANSCRIPTION FACTOR FOXP3;

EID: 79960705112     PISSN: 17512972     EISSN: 17512980     Source Type: Journal    
DOI: 10.1111/j.1751-2980.2011.00505.x     Document Type: Article
Times cited : (77)

References (41)
  • 1
    • 0036218221 scopus 로고    scopus 로고
    • The immunology of mucosal models of inflammation
    • Strober W, Fuss IJ, Blumberg RS. The immunology of mucosal models of inflammation. Annu Rev Immunol 2002; 20: 495-549.
    • (2002) Annu Rev Immunol , vol.20 , pp. 495-549
    • Strober, W.1    Fuss, I.J.2    Blumberg, R.S.3
  • 2
    • 0035819467 scopus 로고    scopus 로고
    • Prospects for research in inflammatory bowel disease
    • Blumberg RS, Strober W. Prospects for research in inflammatory bowel disease. JAMA 2001; 285: 643-7.
    • (2001) JAMA , vol.285 , pp. 643-647
    • Blumberg, R.S.1    Strober, W.2
  • 3
    • 0029586031 scopus 로고
    • Tolerance exists towards resident intestinal flora but is broken in active inflammatory bowel disease (IBD)
    • Duchmann R, Kaiser I, Hermann E, Mayet W, Ewe K, ZumBuschenfelde KHM. Tolerance exists towards resident intestinal flora but is broken in active inflammatory bowel disease (IBD). Clin Exp Immunol 1995; 102: 448-55.
    • (1995) Clin Exp Immunol , vol.102 , pp. 448-455
    • Duchmann, R.1    Kaiser, I.2    Hermann, E.3    Mayet, W.4    Ewe, K.5    ZumBuschenfelde, K.H.M.6
  • 4
    • 0030267661 scopus 로고    scopus 로고
    • Persistent clonal expansions of peripheral blood CD4(+) lymphocytes in chronic inflammatory bowel disease
    • Probert CS, Chott A, Turner JR etal. Persistent clonal expansions of peripheral blood CD4(+) lymphocytes in chronic inflammatory bowel disease. J Immunol 1996; 157: 3183-91.
    • (1996) J Immunol , vol.157 , pp. 3183-3191
    • Probert, C.S.1    Chott, A.2    Turner, J.R.3
  • 5
    • 0032991667 scopus 로고    scopus 로고
    • Epithelial permeability to proteins in the noninflamed ileum of Crohn's disease?
    • Soderholm JD, Peterson KH, Olaison G etal. Epithelial permeability to proteins in the noninflamed ileum of Crohn's disease? Gastroenterology 1999; 117: 65-72.
    • (1999) Gastroenterology , vol.117 , pp. 65-72
    • Soderholm, J.D.1    Peterson, K.H.2    Olaison, G.3
  • 6
    • 0035806244 scopus 로고    scopus 로고
    • Ex vivo isolation and characterization of CD4(+)CD25(+) T cells with regulatory properties from human blood
    • Dieckmann D, Plottner H, Berchtold S, Berger T, Schuler G. Ex vivo isolation and characterization of CD4(+)CD25(+) T cells with regulatory properties from human blood. J Exp Med 2001; 193: 1303-10.
    • (2001) J Exp Med , vol.193 , pp. 1303-1310
    • Dieckmann, D.1    Plottner, H.2    Berchtold, S.3    Berger, T.4    Schuler, G.5
  • 7
    • 0027340328 scopus 로고
    • Self-ignorance in the peripheral T cell pool
    • Miller J, Heath WR. Self-ignorance in the peripheral T cell pool. Immunol Rev 1993; 133: 131-50.
    • (1993) Immunol Rev , vol.133 , pp. 131-150
    • Miller, J.1    Heath, W.R.2
  • 8
    • 0025908321 scopus 로고
    • Peripheral selection of the T cell repertoire
    • Rocha B, Vonboehmer H. Peripheral selection of the T cell repertoire. Science 1991; 251: 1225-8.
    • (1991) Science , vol.251 , pp. 1225-1228
    • Rocha, B.1    Vonboehmer, H.2
  • 9
    • 0025339511 scopus 로고
    • A cell culture model for lymphocyte T clonal anergy
    • Schwartz RH. A cell culture model for lymphocyte T clonal anergy. Science 1990; 248: 1349-56.
    • (1990) Science , vol.248 , pp. 1349-1356
    • Schwartz, R.H.1
  • 10
    • 33646168597 scopus 로고    scopus 로고
    • FOXP3: of mice and men
    • Ziegler SF. FOXP3: of mice and men. Annu Rev Immunol 2006; 24: 209-26.
    • (2006) Annu Rev Immunol , vol.24 , pp. 209-226
    • Ziegler, S.F.1
  • 11
    • 3543140687 scopus 로고    scopus 로고
    • Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNF alpha therapy
    • Ehrenstein MR, Evans JG, Singh A etal. Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNF alpha therapy. J Exp Med 2004; 200: 277-85.
    • (2004) J Exp Med , vol.200 , pp. 277-285
    • Ehrenstein, M.R.1    Evans, J.G.2    Singh, A.3
  • 12
    • 33344457856 scopus 로고    scopus 로고
    • The immune paradox of sarcoidosis and regulatory T cells
    • Miyara M, Amoura Z, Parizot C etal. The immune paradox of sarcoidosis and regulatory T cells. J Exp Med 2006; 203: 359-70.
    • (2006) J Exp Med , vol.203 , pp. 359-370
    • Miyara, M.1    Amoura, Z.2    Parizot, C.3
  • 13
    • 36249014365 scopus 로고    scopus 로고
    • Characterization of FOXP3(+)CD4(+) regulatory T cells in Crohn's disease
    • Saruta M, Yu QT, Fleshner PR etal. Characterization of FOXP3(+)CD4(+) regulatory T cells in Crohn's disease. Clin Immunol 2007; 125: 281-90.
    • (2007) Clin Immunol , vol.125 , pp. 281-290
    • Saruta, M.1    Yu, Q.T.2    Fleshner, P.R.3
  • 14
    • 1842732224 scopus 로고    scopus 로고
    • Loss of functional suppression by CD4(+)CD25(+) regulatory T cells in patients with multiple sclerosis
    • Viglietta V, Baecher-Allan C, Weiner HL, Hafler DA. Loss of functional suppression by CD4(+)CD25(+) regulatory T cells in patients with multiple sclerosis. J Exp Med 2004; 199: 971-9.
    • (2004) J Exp Med , vol.199 , pp. 971-979
    • Viglietta, V.1    Baecher-Allan, C.2    Weiner, H.L.3    Hafler, D.A.4
  • 15
    • 0035675798 scopus 로고    scopus 로고
    • IPEX is a unique X-linked syndrome characterized by immune dysfunction, polyendocrinopathy, enteropathy, and a variety of autoimmune phenomena
    • Bennett CL, Ochs HD. IPEX is a unique X-linked syndrome characterized by immune dysfunction, polyendocrinopathy, enteropathy, and a variety of autoimmune phenomena. Curr Opin Pediatr 2001; 13: 533-8.
    • (2001) Curr Opin Pediatr , vol.13 , pp. 533-538
    • Bennett, C.L.1    Ochs, H.D.2
  • 16
    • 0035163909 scopus 로고    scopus 로고
    • X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy
    • Wildin RS, Ramsdell F, Peake J etal. X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy. Nat Genet 2001; 27: 18-20.
    • (2001) Nat Genet , vol.27 , pp. 18-20
    • Wildin, R.S.1    Ramsdell, F.2    Peake, J.3
  • 17
    • 0042346231 scopus 로고    scopus 로고
    • Scurfin (FOXP3) controls T-dependent immune responses in vivo through regulation of CD4(+) T cell effector function
    • Kasprowicz DJ, Smallwood PS, Tyznik AJ, Ziegler SF. Scurfin (FOXP3) controls T-dependent immune responses in vivo through regulation of CD4(+) T cell effector function. J Immunol 2003; 171: 1216-23.
    • (2003) J Immunol , vol.171 , pp. 1216-1223
    • Kasprowicz, D.J.1    Smallwood, P.S.2    Tyznik, A.J.3    Ziegler, S.F.4
  • 18
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor FOXP3
    • Hori S, Nomura T, Sakaguchi S. Control of regulatory T cell development by the transcription factor FOXP3. Science 2003; 299: 1057-61.
    • (2003) Science , vol.299 , pp. 1057-1061
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 19
    • 8344275995 scopus 로고    scopus 로고
    • Crucial role of FOXP3 in the development and function of human CD25(+)CD4(+) regulatory T cells
    • Yagi H, Nomura T, Nakamura K etal. Crucial role of FOXP3 in the development and function of human CD25(+)CD4(+) regulatory T cells. Int Immunol 2004; 16: 1643-56.
    • (2004) Int Immunol , vol.16 , pp. 1643-1656
    • Yagi, H.1    Nomura, T.2    Nakamura, K.3
  • 20
    • 2142645808 scopus 로고    scopus 로고
    • Cutting edge: TGF-beta induces a regulatory phenotype in CD4+CD25- T cells through FOXP3 induction and down-regulation of Smad7
    • Fantini MC, Becker C, Monteleone G, Pallone F, Galle PR, Neurath MF. Cutting edge: TGF-beta induces a regulatory phenotype in CD4+CD25- T cells through FOXP3 induction and down-regulation of Smad7. J Immunol 2004; 172: 5149-53.
    • (2004) J Immunol , vol.172 , pp. 5149-5153
    • Fantini, M.C.1    Becker, C.2    Monteleone, G.3    Pallone, F.4    Galle, P.R.5    Neurath, M.F.6
  • 21
    • 2442484053 scopus 로고    scopus 로고
    • Naturally arising CD4(+) regulatory T cells for immunologic self-tolerance and negative control of immune responses
    • Sakaguchi S. Naturally arising CD4(+) regulatory T cells for immunologic self-tolerance and negative control of immune responses. Annu Rev Immunol 2004; 22: 531-62.
    • (2004) Annu Rev Immunol , vol.22 , pp. 531-562
    • Sakaguchi, S.1
  • 22
    • 33745275219 scopus 로고    scopus 로고
    • Functional CD4(+)CD25(high) regulatory T cells are enriched in the colonic mucosa of patients with active ulcerative colitis and increase with disease activity
    • Holmen N, Lundgren A, Lundin S etal. Functional CD4(+)CD25(high) regulatory T cells are enriched in the colonic mucosa of patients with active ulcerative colitis and increase with disease activity. Inflamm Bowel Dis 2006; 12: 447-56.
    • (2006) Inflamm Bowel Dis , vol.12 , pp. 447-456
    • Holmen, N.1    Lundgren, A.2    Lundin, S.3
  • 23
    • 0037243827 scopus 로고    scopus 로고
    • CD4(+)CD25(+) T-R cells suppress innate immune pathology through cytokine-dependent mechanisms
    • Maloy KJ, Salaun L, Cahill R, Dougan G, Saunders NJ, Powrie F. CD4(+)CD25(+) T-R cells suppress innate immune pathology through cytokine-dependent mechanisms. J Exp Med 2003; 197: 111-9.
    • (2003) J Exp Med , vol.197 , pp. 111-119
    • Maloy, K.J.1    Salaun, L.2    Cahill, R.3    Dougan, G.4    Saunders, N.J.5    Powrie, F.6
  • 24
    • 22644437303 scopus 로고    scopus 로고
    • CD4(+)CD25(+)-regulatory T cells from mouse to man
    • Wing K, Suri-Payer E, Rudin A. CD4(+)CD25(+)-regulatory T cells from mouse to man. Scand J Immunol 2005; 62: 1-15.
    • (2005) Scand J Immunol , vol.62 , pp. 1-15
    • Wing, K.1    Suri-Payer, E.2    Rudin, A.3
  • 25
    • 0018292707 scopus 로고
    • Rederived values the 8 coefficients of the Crohn disease activity index (CDAI)
    • Best WR, Becktel JM, Singleton JW. Rederived values the 8 coefficients of the Crohn disease activity index (CDAI). Gastroenterology 1979; 77: 843-6.
    • (1979) Gastroenterology , vol.77 , pp. 843-846
    • Best, W.R.1    Becktel, J.M.2    Singleton, J.W.3
  • 26
    • 0024587677 scopus 로고
    • Coated mesalazine (5-aminosalicylic acid) versus sulphasalazine in the treatment of active ulcerative colitis - a randomized trial
    • Rachmilewitz D. Coated mesalazine (5-aminosalicylic acid) versus sulphasalazine in the treatment of active ulcerative colitis - a randomized trial. Br Med J 1989; 298: 82-6.
    • (1989) Br Med J , vol.298 , pp. 82-86
    • Rachmilewitz, D.1
  • 27
    • 29244460617 scopus 로고    scopus 로고
    • Increase of CD4+CD25+ regulatory T cells in peripheral blood of patients with chronic hepatitis C
    • Yang J-H, Zhang Y-X, Su C, Sun N-X. Increase of CD4+CD25+ regulatory T cells in peripheral blood of patients with chronic hepatitis C. Shijie Huaren Xiaohua Zazhi 2005; 13: 2201-4.
    • (2005) Shijie Huaren Xiaohua Zazhi , vol.13 , pp. 2201-2204
    • Yang, J.-H.1    Zhang, Y.-X.2    Su, C.3    Sun, N.-X.4
  • 28
    • 3543097547 scopus 로고    scopus 로고
    • Suppressor T cells in human diseases
    • Baecher-Allan C, Hafler DA. Suppressor T cells in human diseases. J Exp Med 2004; 200: 273-6.
    • (2004) J Exp Med , vol.200 , pp. 273-276
    • Baecher-Allan, C.1    Hafler, D.A.2
  • 29
    • 0037099733 scopus 로고    scopus 로고
    • Human CD4(+)CD25(+) regulatory, contact-dependent T cells induce interleukin 1-producing, contact-independent type 1-like regulatory T cells
    • Dieckmann D, Bruett CH, Ploettner H, Lutz MB, Schuler G. Human CD4(+)CD25(+) regulatory, contact-dependent T cells induce interleukin 1-producing, contact-independent type 1-like regulatory T cells. J Exp Med 2002; 196: 247-53.
    • (2002) J Exp Med , vol.196 , pp. 247-253
    • Dieckmann, D.1    Bruett, C.H.2    Ploettner, H.3    Lutz, M.B.4    Schuler, G.5
  • 30
    • 0036886390 scopus 로고    scopus 로고
    • The role of IL-10 and TGF-beta in the differentiation and effector function of T regulatory cells
    • Levings MK, Bacchetta R, Schulz U, Roncarolo MG. The role of IL-10 and TGF-beta in the differentiation and effector function of T regulatory cells. Int Arch Allergy Immunol 2002; 129: 263-76.
    • (2002) Int Arch Allergy Immunol , vol.129 , pp. 263-276
    • Levings, M.K.1    Bacchetta, R.2    Schulz, U.3    Roncarolo, M.G.4
  • 31
    • 66549093255 scopus 로고    scopus 로고
    • Regulatory T cells fail to suppress CD4(+) T-bet(+) T cells in relapsing multiple sclerosis patients
    • Frisullo G, Nociti V, Iorio R etal. Regulatory T cells fail to suppress CD4(+) T-bet(+) T cells in relapsing multiple sclerosis patients. Immunology 2009; 127: 418-28.
    • (2009) Immunology , vol.127 , pp. 418-428
    • Frisullo, G.1    Nociti, V.2    Iorio, R.3
  • 32
    • 65449149735 scopus 로고    scopus 로고
    • Altered homeostasis of CD4(+) FoxP3(+) regulatory T-cell subpopulations in systemic lupus erythematosus
    • Suen JL, Li HT, Jong YJ, Chiang BL, Yen JH. Altered homeostasis of CD4(+) FoxP3(+) regulatory T-cell subpopulations in systemic lupus erythematosus. Immunology 2009; 127: 196-205.
    • (2009) Immunology , vol.127 , pp. 196-205
    • Suen, J.L.1    Li, H.T.2    Jong, Y.J.3    Chiang, B.L.4    Yen, J.H.5
  • 34
    • 20444434616 scopus 로고    scopus 로고
    • Peripheral and intestinal regulatory CD4+CD25(high) T cells in inflammatory bowel disease
    • Maul J, Loddenkemper C, Mundt P etal. Peripheral and intestinal regulatory CD4+CD25(high) T cells in inflammatory bowel disease. Gastroenterology 2005; 128: 1868-78.
    • (2005) Gastroenterology , vol.128 , pp. 1868-1878
    • Maul, J.1    Loddenkemper, C.2    Mundt, P.3
  • 36
    • 0026095235 scopus 로고
    • Increased activation of isolated intestinal lamina propria mononuclear cells in inflammatory bowel disease
    • Schreiber S, MacDermott RP, Raedler A, Pinnau R, Bertovich MJ, Nash GS. Increased activation of isolated intestinal lamina propria mononuclear cells in inflammatory bowel disease. Gastroenterology 1991; 101: 1020-30.
    • (1991) Gastroenterology , vol.101 , pp. 1020-1030
    • Schreiber, S.1    MacDermott, R.P.2    Raedler, A.3    Pinnau, R.4    Bertovich, M.J.5    Nash, G.S.6
  • 37
    • 0023219626 scopus 로고
    • Activation of peripheral blood and intestinal lamina propria lymphocytes in Crohn's disease. In vivo state of activation and in vitro response to stimulation as defined by the expression of early activation antigens
    • Pallone F, Fais S, Squarcia O, Biancone L, Pozzilli P, Boirivant M. Activation of peripheral blood and intestinal lamina propria lymphocytes in Crohn's disease. In vivo state of activation and in vitro response to stimulation as defined by the expression of early activation antigens. Gut 1987; 28: 745-53.
    • (1987) Gut , vol.28 , pp. 745-753
    • Pallone, F.1    Fais, S.2    Squarcia, O.3    Biancone, L.4    Pozzilli, P.5    Boirivant, M.6
  • 38
    • 0037446531 scopus 로고    scopus 로고
    • Cutting edge: cure of colitis by CD4(+) CD25(+) regulatory T cells
    • Mottet C, Uhlig HH, Powrie F. Cutting edge: cure of colitis by CD4(+) CD25(+) regulatory T cells. J Immunol 2003; 170: 3939-43.
    • (2003) J Immunol , vol.170 , pp. 3939-3943
    • Mottet, C.1    Uhlig, H.H.2    Powrie, F.3
  • 39
    • 0037436119 scopus 로고    scopus 로고
    • Toll pathway-dependent blockade of CD4(+)CD25(+) T cell-mediated suppression by dendritic cells
    • Pasare C, Medzhitov R. Toll pathway-dependent blockade of CD4(+)CD25(+) T cell-mediated suppression by dendritic cells. Science 2003; 299: 1033-6.
    • (2003) Science , vol.299 , pp. 1033-1036
    • Pasare, C.1    Medzhitov, R.2
  • 40
    • 23944509107 scopus 로고    scopus 로고
    • Toll-like, receptor 8-mediated reversal of CD4(+) regulatory T cell function
    • Peng GY, Guo Z, Kiniwa Y etal. Toll-like, receptor 8-mediated reversal of CD4(+) regulatory T cell function. Science 2005; 309: 1380-4.
    • (2005) Science , vol.309 , pp. 1380-1384
    • Peng, G.Y.1    Guo, Z.2    Kiniwa, Y.3
  • 41
    • 0036883944 scopus 로고    scopus 로고
    • Inhibition of human CD4(+)CD25(+high) regulatory T cell function
    • Baecher-Allan C, Viglietta V, Hafler DA. Inhibition of human CD4(+)CD25(+high) regulatory T cell function. J Immunol 2002; 169: 6210-7.
    • (2002) J Immunol , vol.169 , pp. 6210-6217
    • Baecher-Allan, C.1    Viglietta, V.2    Hafler, D.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.