Sodium channel molecular conformations and antiarrhythmic drug affinity

Trends in Cardiovascular Medicine

Volumn 20, Issue 1, 2010, Pages 16-21

  Sheets, Michael F ^a   Fozzard, Harry A ^b   Lipkind, Gregory M ^b   Hanck, Dorothy A ^b  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIARRHYTHMIC AGENT; BUPIVACAINE; COCAINE; FLECAINIDE; LIDOCAINE; LIDOCAINE ETHOBROMIDE; MEPIVACAINE; MEXILETINE; N [(2,6 DIMETHYLPHENYL)CARBAMOYLMETHYL]TRIMETHYLAMMONIUM; POTASSIUM CHANNEL; PROCAINAMIDE; QUINIDINE; SODIUM CHANNEL; SODIUM CHANNEL BLOCKING AGENT;

BINDING AFFINITY; CONFORMATION; CRYSTAL STRUCTURE; DRUG MECHANISM; HUMAN; PRIORITY JOURNAL; REVIEW; SODIUM CURRENT; STEADY STATE;

ANIMALS; ANTI-ARRHYTHMIA AGENTS; HUMANS; ION CHANNEL GATING; LIDOCAINE; MODELS, MOLECULAR; MOLECULAR STRUCTURE; MUTAGENESIS, SITE-DIRECTED; PROTEIN CONFORMATION; SODIUM; SODIUM CHANNEL BLOCKERS; SODIUM CHANNELS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 78549281090     PISSN: 10501738     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tcm.2010.03.002     Document Type: Review

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