α-Lipoic acid increases tolerance of cardiomyoblasts to glucose/glucose oxidase-induced injury via ROS-dependent ERK1/2 activation

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1823, Issue 4, 2012, Pages 920-929

  Yao, Yuzhen ^a   Li, Rongrong ^a   Ma, Yujie ^a   Wang, Xiaohui ^a   Li, Chuanfu ^b   Zhang, Xiaojin ^a   Ma, Rong ^a   Ding, Zhengnian ^a   Liu, Li ^a  

^a THE FIRST AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

^b East Tennessee State University   (United States)

Author keywords

lipoic acid; Apoptosis; ERK1 2; High glucose; Reactive oxygen specie

Indexed keywords

GLUCOSE; GLUCOSE OXIDASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; REACTIVE OXYGEN METABOLITE; THIOCTIC ACID;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DAMAGE; CELL PROLIFERATION; CELL PROTECTION; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVATION; HEART MUSCLE CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

ACETYLCYSTEINE; ANIMALS; APOPTOSIS; CELL SURVIVAL; CYTOPROTECTION; ENZYME ACTIVATION; GLUCOSE; GLUCOSE OXIDASE; HYDROGEN PEROXIDE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MYOCYTES, CARDIAC; RATS; REACTIVE OXYGEN SPECIES; THIOCTIC ACID;

RATTUS;

EID: 84862786919     PISSN: 01674889     EISSN: 18792596     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2012.02.005     Document Type: Article

References (36)

1. Cai L., Wang Y., Zhou G., Chen T., Song Y., Li X., Kang Y.J. Attenuation by metallothionein of early cardiac cell death via suppression of mitochondrial oxidative stress results in a prevention of diabetic cardiomyopathy. J. Am. Coll. Cardiol. 2006, 48:1688-1697.
2. Shen E., Li Y., Li Y., Shan L., Zhu H., Feng Q., Arnold J.M., Peng T. Rac1 is required for cardiomyocyte apoptosis during hyperglycemia. Diabetes 2009, 58:2386-2395.
3. Cai L., Kang Y.J. Oxidative stress and diabetic cardiomyopathy: a brief review. Cardiovasc. Toxicol. 2001, 1:181-193.
4. Wang X., Wang Z., Yao Y., Li J., Zhang X., Li C., Cheng Y., Ding G., Liu L., Ding Z. Essential role of ERK activation in neurite outgrowth induced by α-lipoic acid. Biochim. Biophys. Acta 2011, 1813:827-838.
5. Wang X., Zhang X., Cheng Y., Li C., Zhang W., Liu L., Ding Z. Alpha-Lipoic acid prevents bupivacaine-induced neuron injury in vitro through a PI3K/Akt-dependent mechanism. Neurotoxicology 2010, 31:101-112.
6. Simbula G., Columbano A., Ledda-Columbano G.M., Sanna L., Deidda M., Diana A., Pibiri M. Increased ROS generation and p53 activation in alpha-lipoic acid-induced apoptosis of hepatoma cells. Apoptosis 2007, 12:113-123.
7. Dicter N., Madar Z., Tirosh O. Alpha-lipoic acid inhibits glycogen synthesis in rat soleus muscle via its oxidative activity and the uncoupling of mitochondria. J. Nutr. 2002, 132:3001-3006.
8. Groeger G., Mackey A.M., Pettigrew C.A., Bhatt L., Cotter T.G. Stress-induced activation of Nox contributes to cell survival signaling via production of hydrogen peroxide. J. Neurochem. 2009, 109:1544-1554.
9. Mackey A.M., Sanvicens N., Groeger G., Doonan F., Wallace D., Cotter T.G. Redox survival signaling in retina-derived 661W cells. Cell Death Differ. 2008, 15:1291-1303.
10. Shay K.P., Moreau R.F., Smith E.J., Smith A.R., Hagen T.M. Alpha-lipoic acid as a dietary supplement: molecular mechanisms and therapeutic potential. Biochim. Biophys. Acta 2009, 1790:1149-1460.
11. Kowluru R.A., Odenbach S. Effect of long-term administration of alpha-lipoic acid on retinal capillary cell death and the development of retinopathy in diabetic rats. Diabetes 2004, 53:3233-3238.
12. Siu B., Saha J., Smoyer W.E., Sullivan K.A., FC Brosius, Reduction in podocyte density as a pathologic feature in early diabetic nephropathy in rodents: prevention by lipoic acid treatment. BMC Nephrol. 2006, 7:6.
13. Kim S.H., Choi M., Lee Y., Kim Y.O., Ahn D.S., Kim Y.H., Kang E.S., Lee E.J., Jung M., Cho J.W., Williams D.R., Lee H.C. Natural therapeutic magnesium lithospermate B potently protects the endothelium from hyperglycaemia-induced dysfunction. Cardiovasc. Res. 2010, 87:713-722.
14. Ghibu S., Richard C., Vergely C., Zeller M., Cottin Y., Rochette L. Antioxidant properties of an endogenous thiol: alpha-lipoic acid, useful in the prevention of cardiovascular diseases. J. Cardiovasc. Pharmacol. 2009, 54:391-398.
15. Wang J., Wang H., Hao P., Xue L., Wei S., Zhang Y., Chen Y. Inhibition of aldehyde dehydrogenase 2 by oxidative stress is associated with cardiac dysfunction in diabetic rats. Mol. Med. 2011, 17:172-179.
16. Palacka P., Kucharska J., Murin J., Dostalova K., Okkelova A., Cizova M., Waczulikova I., Moricova S., Gvozdjakova A. Complementary therapy in diabetic patients with chronic complications: a pilot study. Bratisl. Lek. Listy 2010, 111:205-211.
17. Kumar S., Sitasawad S.L. N-acetylcysteine prevents glucose/glucose oxidase-induced oxidative stress, mitochondrial damage and apoptosis in H9c2 cells. Life Sci. 2009, 84:328-336.
18. Lin C.J., Ho H.Y., Cheng M.L., You T.H., Yu J.S., Chiu D.T. Impaired dephosphorylation renders G6PD-knockdown HepG2 cells more susceptible to H(2)O(2)-induced apoptosis. Free Radic. Biol. Med. 2010, 49:361-373.
19. Rosenbaugh E.G., Roat J.W., Gao L., Yang R.F., Manickam D.S., Yin J.X., Schultz H.D., Bronich T.K., Batrakova E.V., Kabanov A.V., Zucker I.H., Zimmerman M.C. The attenuation of central angiotensin II-dependent pressor response and intra-neuronal signaling by intracarotid injection of nanoformulated copper/zinc superoxide dismutase. Biomaterials 2010, 31:5218-5226.
20. Robinson K.M., Janes M.S., Pehar M., Monette J.S., Ross M.F., Hagen T.M., Murphy M.P., Beckman J.S. Selective fleorescent imaging of superoxide in vivo using ethidium-based probes. Proc. Natl. Acad. Sci. U. S. A. 2006, 103:15038-15043.
21. Celojevic D., Petersen A., Karlsson J.O., Behndig A., Zetterberg M. Effects of 17β-estradiol on proliferation, cell viability and intracellular redox status in native human lens epithelial cells. Mol. Vis. 2011, 17:1987-1996.
22. Ma R., Wang X., Lu C., Li C., Cheng Y., Ding G., Liu L., Ding Z. Dexamethasone attenuated bupivacaine-induced neuron injury in vitro through a threonine-serine protein kinase B-dependent mechanism. Neuroscience 2010, 167:329-342.
23. Salido M., Gonzalez J.L., Vilches J. Loss of mitochondrial membrane potential is inhibited by bombesin in etoposide-induced apoptosis in PC-3 prostate carcinoma cells. Mol. Cancer Ther. 2007, 6:1292-1299.
24. Lee S.T., Wong P.F., Cheah S.C., Mustafa M.R. Alpha-tomatine induces apoptosis and inhibits nuclear factor-kappa B activation on human prostatic adenocarcinoma PC-3 cells. PLoS One 2011, 6:e18915.
25. Rygiel T.P., Mertens A.E., Strumane K., van der Kammen R., Collard J.G. The Rac activator Tiam1 prevents keratinocyte apoptosis by controlling ROS-mediated ERK phosphorylation. J. Cell Sci. 2008, 121:1183-1192.
26. RM Kluck, Bossy-Wetzel E., Green D.R., Newmeyer D.D. The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis. Science 1997, 275:1132-1136.
27. Green D.R., Reed J.C. Mitochondria and apoptosis. Science 1998, 281:1309-1312.
28. Bitar M.S., Ayed A.K., Abdel-Halim S.M., Isenovic E.R., Al-Mulla F. Inflammation and apoptosis in aortic tissues of aged type II diabetes: amelioration with alpha-lipoic acid through phosphatidylinositol 3-kinase/Akt- dependent mechanism. Life Sci. 2010, 86:844-853.
29. Kowluru R.A. Diabetic retinopathy: mitochondrial dysfunction and retinal capillary cell death. Antioxid. Redox Signal. 2005, 7:1581-1587.
30. Costes S., Broca C., Bertrand G., Lajoix A.D., Bataille D., Bockaert J., Dalle S. ERK1/2 control phosphorylation and protein level of cAMP-responsive element-binding protein: a key role in glucose-mediated pancreatic beta-cell survival. Diabetes 2006, 55:2220-2230.
31. Wente W., Efanov A.M., Brenner M., Kharitonenkov A., Köster A., Sandusky G.E., Sewing S., Treinies I., Zitzer H., Gromada J. Fibroblast growth factor-21 improves pancreatic beta-cell function and survival by activation of extracellular signal-regulated kinase 1/2 and Akt signaling pathways. Diabetes 2006, 55:2470-2478.
32. Moini H., Packer L., Saris N.E. Antioxidant and prooxidant activities of alpha-lipoic acid and dihydrolipoic acid. Toxicol. Appl. Pharmacol. 2002, 182:84-90.
33. Moungjaroen J., Nimmannit U., Callery P.S., Wang L., Azad N., Lipipun V., Chanvorachote P., Rojanasakul Y. Reactive oxygen species mediate caspase activation and apoptosis induced by lipoic acid inhuman lung epithelial cancer cells through Bcl-2 down-regulation. J. Pharmacol. Exp. Ther. 2006, 319:1062-1069.
34. Oh P.S., Lim K.T. Protective activity of 30kDa phytoglycoprotein from glucose/glucose oxidase-induced cell death in primary cultured mouse thymocytes. Environ. Toxicol. Pharmacol. 2008, 25:114-120.
35. Ko J.H., Lee S.J., Lim K.T. 116 kDa glycoprotein isolated from Ulmus davidiana Nakai (UDN) inhibits glucose/glucose oxidase (G/GO)-induced apoptosis in BNL CL.2 cells. J. Ethnopharmacol. 2005, 100:339-346.
36. Toledano M.B., Planson A.G., Delaunay-Moisan A. Reining in H(2)O(2) for safe signaling. Cell 2010, 140:454-456.