-
1
-
-
0031897103
-
Prevalence of diabetes, impaired fasting glucose, and impaired glucose tolerance in U.S. adults. The Third National Health and Nutrition Examination Survey, 1988-1994
-
Harris, M. I., Flegal, K. M., Cowie, C. C., Eberhardt, M. S., Goldstein, D. E., Little, R. R.,Wiedmeyer, H. M. & Byrd-Holt, D. D. (1998) Prevalence of diabetes, impaired fasting glucose, and impaired glucose tolerance in U.S. adults. The Third National Health and Nutrition Examination Survey, 1988-1994. Diabetes Care 21: 518-524.
-
(1998)
Diabetes Care
, vol.21
, pp. 518-524
-
-
Harris, M.I.1
Flegal, K.M.2
Cowie, C.C.3
Eberhardt, M.S.4
Goldstein, D.E.5
Little, R.R.6
Wiedmeyer, H.M.7
Byrd-Holt, D.D.8
-
2
-
-
0029873574
-
Genetics of non-insulin-dependent (type-II) diabetes mellitus
-
Kahn, C. R., Vicent, D. & Doria, A. (1996) Genetics of non-insulin-dependent (type-II) diabetes mellitus. Annu. Rev. Med. 47: 509-531.
-
(1996)
Annu. Rev. Med.
, vol.47
, pp. 509-531
-
-
Kahn, C.R.1
Vicent, D.2
Doria, A.3
-
3
-
-
0033536157
-
Cellular mechanisms of insulin resistance in humans
-
Shulman, G. I. (1999) Cellular mechanisms of insulin resistance in humans. Am. J. Cardiol. 84: 3J-10J.
-
(1999)
Am. J. Cardiol.
, vol.84
-
-
Shulman, G.I.1
-
4
-
-
0033533596
-
Diabetes and cardiovascular disease: A statement for healthcare professionals from the American Heart Association
-
Grundy, S. M., Benjamin, I. J., Burke, G. L., Chait, A., Eckel, R. H., Howard, B. V., Mitch, W., Smith, S. C., Jr. & Sowers, J. R. (1999) Diabetes and cardiovascular disease: a statement for healthcare professionals from the American Heart Association. Circulation 100: 1134-1146.
-
(1999)
Circulation
, vol.100
, pp. 1134-1146
-
-
Grundy, S.M.1
Benjamin, I.J.2
Burke, G.L.3
Chait, A.4
Eckel, R.H.5
Howard, B.V.6
Mitch, W.7
Smith S.C., Jr.8
Sowers, J.R.9
-
5
-
-
0033595120
-
Impaired glucose transport as a cause of decreased insulin-stimulated muscle glycogen synthesis in type 2 diabetes
-
Cline, G. W., Petersen, K. F., Krssak, M., Shen, J., Hundal, R. S., Trajanoski, Z., Inzucchi, S., Dresner, A., Rothman, D. L. & Shulman, G. 1. (1999) Impaired glucose transport as a cause of decreased insulin-stimulated muscle glycogen synthesis in type 2 diabetes. N. Engl. J. Med. 341: 240-246.
-
(1999)
N. Engl. J. Med.
, vol.341
, pp. 240-246
-
-
Cline, G.W.1
Petersen, K.F.2
Krssak, M.3
Shen, J.4
Hundal, R.S.5
Trajanoski, Z.6
Inzucchi, S.7
Dresner, A.8
Rothman, D.L.9
Shulman, G.I.10
-
6
-
-
0033536189
-
Insulin resistance and lipid metabolism
-
Howard, B. V. (1999) Insulin resistance and lipid metabolism. Am. J. Cardiol. 84: 28J-32J.
-
(1999)
Am. J. Cardiol.
, vol.84
-
-
Howard, B.V.1
-
7
-
-
0000197851
-
α-lipoic acid: A metabolic antioxidant and potential redox modulator of transcription
-
Packer, L., Roy, S. & Sen, C. K. (1997) α-Lipoic acid: a metabolic antioxidant and potential redox modulator of transcription. Adv. Pharmacol. 38: 79-101.
-
(1997)
Adv. Pharmacol.
, vol.38
, pp. 79-101
-
-
Packer, L.1
Roy, S.2
Sen, C.K.3
-
8
-
-
0034064348
-
Engagement of the insulin-sensitive pathway in the stimulation of glucose transport by α-lipoic acid in 3T3-L1 adipocytes
-
Yaworsky, K., Somwar, R., Ramlal, T., Tritschler, H. J. & Klip, A. (2000) Engagement of the insulin-sensitive pathway in the stimulation of glucose transport by α-lipoic acid in 3T3-L1 adipocytes. Diabetologia 43: 294-303.
-
(2000)
Diabetologia
, vol.43
, pp. 294-303
-
-
Yaworsky, K.1
Somwar, R.2
Ramlal, T.3
Tritschler, H.J.4
Klip, A.5
-
9
-
-
0029908330
-
Stimulation of glucose uptake by the natural coenzyme α-lipoic acid/thioctic acid: Participation of elements of the insulin signaling pathway
-
Estrada, D. E., Ewart, H. S., Tsakiridis, T., Volchuk, A., Ramlal, T., Tritschler, H. & Klip, A. (1996) Stimulation of glucose uptake by the natural coenzyme α-lipoic acid/thioctic acid: participation of elements of the insulin signaling pathway. Diabetes 45: 1798-1804.
-
(1996)
Diabetes
, vol.45
, pp. 1798-1804
-
-
Estrada, D.E.1
Ewart, H.S.2
Tsakiridis, T.3
Volchuk, A.4
Ramlal, T.5
Tritschler, H.6
Klip, A.7
-
10
-
-
0030809515
-
Lipoic acid reduces glycemia and increases muscle GLUT4 content in streptozotocin-diabetic rats
-
Khamaisi, M., Potashnik, R., Tirosh, A., Demshchak, E., Rudich, A., Tritschler, H., Wessel, K. & Bashan, N. (1997) Lipoic acid reduces glycemia and increases muscle GLUT4 content in streptozotocin-diabetic rats. Metabolism 46: 763-768.
-
(1997)
Metabolism
, vol.46
, pp. 763-768
-
-
Khamaisi, M.1
Potashnik, R.2
Tirosh, A.3
Demshchak, E.4
Rudich, A.5
Tritschler, H.6
Wessel, K.7
Bashan, N.8
-
11
-
-
0032904416
-
α-lipoic acid treatment decreases serum lactate and pyruvate concentrations and improves glucose effectiveness in lean and obese patients with type 2 diabetes
-
Konrad, T., Vicini, P., Kusterer, K., Hoflich, A., Assadkhani, A., Bohles, H. J., Sewell, A., Tritschler, H. J., Cobelli, C. & Usadel, K. H. (1999) α-Lipoic acid treatment decreases serum lactate and pyruvate concentrations and improves glucose effectiveness in lean and obese patients with type 2 diabetes. Diabetes Care 22: 280-287.
-
(1999)
Diabetes Care
, vol.22
, pp. 280-287
-
-
Konrad, T.1
Vicini, P.2
Kusterer, K.3
Hoflich, A.4
Assadkhani, A.5
Bohles, H.J.6
Sewell, A.7
Tritschler, H.J.8
Cobelli, C.9
Usadel, K.H.10
-
12
-
-
0032840875
-
Oral administration of rac-α-lipoic acid modulates insulin sensitivity in patients with type-2 diabetes mellitus: A placebo-controlled pilot trial
-
Jacob, S., Ruus, P., Hermann, R., Tritschler, H. J., Maerker, E., Renn, W., Augustin, H. J., Dietze, G. J. & Rett, K. (1999) Oral administration of rac-α-lipoic acid modulates insulin sensitivity in patients with type-2 diabetes mellitus: a placebo-controlled pilot trial. Free Radic. Biol. Med. 27: 309-314.
-
(1999)
Free Radic. Biol. Med.
, vol.27
, pp. 309-314
-
-
Jacob, S.1
Ruus, P.2
Hermann, R.3
Tritschler, H.J.4
Maerker, E.5
Renn, W.6
Augustin, H.J.7
Dietze, G.J.8
Rett, K.9
-
13
-
-
0029144678
-
Enhancement of glucose disposal in patients with type 2 diabetes by α-lipoic acid
-
Jacob, S., Henriksen, E. J., Schiemann, A. L., Simon, I., Clancy, D. E., Tritschler, H. J., Jung, W. I., Augustin, H. J. & Dietze, G. J. (1995) Enhancement of glucose disposal in patients with type 2 diabetes by α-lipoic acid. Arzneimittelforschung 45: 872-874.
-
(1995)
Arzneimittelforschung
, vol.45
, pp. 872-874
-
-
Jacob, S.1
Henriksen, E.J.2
Schiemann, A.L.3
Simon, I.4
Clancy, D.E.5
Tritschler, H.J.6
Jung, W.I.7
Augustin, H.J.8
Dietze, G.J.9
-
14
-
-
0031028636
-
Effects of treatment with the antioxidant α-lipoic acid on cardiac autonomic neuropathy in NIDDM patients. A 4-month randomized controlled multicenter trial (DEKAN Study)
-
Deutsche Kardiale Autonome Neuropathie
-
Ziegler, D., Schatz, H., Conrad, F., Gries, F. A., Ulrich, H. & Reichel, G. (1997) Effects of treatment with the antioxidant α-lipoic acid on cardiac autonomic neuropathy in NIDDM patients. A 4-month randomized controlled multicenter trial (DEKAN Study). Deutsche Kardiale Autonome Neuropathie. Diabetes Care 20: 369-373.
-
(1997)
Diabetes Care
, vol.20
, pp. 369-373
-
-
Ziegler, D.1
Schatz, H.2
Conrad, F.3
Gries, F.A.4
Ulrich, H.5
Reichel, G.6
-
15
-
-
0032702870
-
α-lipoic acid in the treatment of diabetic polyneuropathy in Germany: Current evidence from clinical trials
-
Ziegler, D., Reljanovic, M., Mehnert, H. & Gries, F. A. (1999) α-Lipoic acid in the treatment of diabetic polyneuropathy in Germany: current evidence from clinical trials. Exp. Clin. Endocrinol. Diabetes 107: 421-430.
-
(1999)
Exp. Clin. Endocrinol. Diabetes
, vol.107
, pp. 421-430
-
-
Ziegler, D.1
Reljanovic, M.2
Mehnert, H.3
Gries, F.A.4
-
16
-
-
0033007122
-
Cytokine-induced glucose uptake in skeletal muscle: Redox regulation and the role of α-lipoic acid
-
Khanna, S., Roy, S., Packer, L. & Sen, C. K. (1999) Cytokine-induced glucose uptake in skeletal muscle: redox regulation and the role of α-lipoic acid. Am. J. Physiol. 276: R1327-R1333.
-
(1999)
Am. J. Physiol.
, vol.276
-
-
Khanna, S.1
Roy, S.2
Packer, L.3
Sen, C.K.4
-
17
-
-
0037082117
-
R-αlipoic acid action on cell redox status, the insulin receptor, and glucose uptake in 3T3-L1 adipocytes
-
Moini, H., Tirosh, O., Park, Y. C., Cho, K. J. & Packer, L. (2002) R-αlipoic acid action on cell redox status, the insulin receptor, and glucose uptake in 3T3-L1 adipocytes. Arch. Biochem. Biophys. 397: 384-391.
-
(2002)
Arch. Biochem. Biophys.
, vol.397
, pp. 384-391
-
-
Moini, H.1
Tirosh, O.2
Park, Y.C.3
Cho, K.J.4
Packer, L.5
-
18
-
-
0029742327
-
The antioxidant α-lipoic acid enhances insulin-stimulated glucose metabolism in insulin-resistant rat skeletal muscle
-
Jacob, S., Streeper, R. S., Fogt, D. L., Hokama, J. Y., Tritschler, H. J., Dietze, G. J. & Henriksen, E. J. (1996) The antioxidant α-lipoic acid enhances insulin-stimulated glucose metabolism in insulin-resistant rat skeletal muscle. Diabetes 45: 1024-1029.
-
(1996)
Diabetes
, vol.45
, pp. 1024-1029
-
-
Jacob, S.1
Streeper, R.S.2
Fogt, D.L.3
Hokama, J.Y.4
Tritschler, H.J.5
Dietze, G.J.6
Henriksen, E.J.7
-
19
-
-
0030840042
-
Differential effects of lipoic acid stereoisomers on glucose metabolism in insulin-resistant skeletal muscle
-
Streeper, R. S., Henriksen, E. J., Jacob, S., Hokama, J. Y., Fogt, D. L. & Tritschler, H. J. (1997) Differential effects of lipoic acid stereoisomers on glucose metabolism in insulin-resistant skeletal muscle. Am. J. Physiol. 273: E185-E191.
-
(1997)
Am. J. Physiol.
, vol.273
-
-
Streeper, R.S.1
Henriksen, E.J.2
Jacob, S.3
Hokama, J.Y.4
Fogt, D.L.5
Tritschler, H.J.6
-
20
-
-
0031577262
-
Stimulation by α-lipoic acid of glucose transport activity in skeletal muscle of lean and obese Zucker rats
-
Henriksen, E. J., Jacob, S., Streeper, R. S., Fogt, D. L., Hokama, J. Y. & Tritschler, H. J. (1997) Stimulation by α-lipoic acid of glucose transport activity in skeletal muscle of lean and obese Zucker rats. Life Sci. 61: 805-812.
-
(1997)
Life Sci.
, vol.61
, pp. 805-812
-
-
Henriksen, E.J.1
Jacob, S.2
Streeper, R.S.3
Fogt, D.L.4
Hokama, J.Y.5
Tritschler, H.J.6
-
22
-
-
0035900777
-
Sulfur-centered radical formation from the antioxidant dihydrolipoic acid
-
Mottley, C. & Mason, R. P. (2001) Sulfur-centered radical formation from the antioxidant dihydrolipoic acid. J. Biol. Chem. 276: 42677-42683.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 42677-42683
-
-
Mottley, C.1
Mason, R.P.2
-
23
-
-
0031743135
-
Investigations on the pharmacokinetics of α-lipoic acid in healthy volunteers
-
Teichert, J., Kern, J., Tritschler, H. J., Ulrich, H. & Preiss, R. (1998) Investigations on the pharmacokinetics of α-lipoic acid in healthy volunteers. Int. J. Clin. Pharmacol. Ther. 36: 625-628.
-
(1998)
Int. J. Clin. Pharmacol. Ther.
, vol.36
, pp. 625-628
-
-
Teichert, J.1
Kern, J.2
Tritschler, H.J.3
Ulrich, H.4
Preiss, R.5
-
24
-
-
0031761354
-
Determination of oxidized and reduced lipoic acid using high-performance liquid chromatography and coulometric detection
-
Sen, C. K., Roy, S., Khanna, S. & Packer, L. (1999) Determination of oxidized and reduced lipoic acid using high-performance liquid chromatography and coulometric detection. Methods Enzymol. 299: 239-246.
-
(1999)
Methods Enzymol.
, vol.299
, pp. 239-246
-
-
Sen, C.K.1
Roy, S.2
Khanna, S.3
Packer, L.4
-
25
-
-
0032527948
-
Antioxidant regulation of phorbol ester-induced adhesion of human Jurkat T-cells to endothelial cells
-
Roy, S., Sen, C. K., Kobuchi, H. & Packer, L. (1998) Antioxidant regulation of phorbol ester-induced adhesion of human Jurkat T-cells to endothelial cells. Free Radic. Biol. Med. 25: 229-241.
-
(1998)
Free Radic. Biol. Med.
, vol.25
, pp. 229-241
-
-
Roy, S.1
Sen, C.K.2
Kobuchi, H.3
Packer, L.4
-
26
-
-
0032985492
-
Neuroprotective effects of α-lipoic acid and its positively charged amide analogue
-
Tirosh, O., Sen, C. K., Roy, S., Kobayashi, M. S. & Packer, L. (1999) Neuroprotective effects of α-lipoic acid and its positively charged amide analogue. Free Radic. Biol. Med. 26: 1418-1426.
-
(1999)
Free Radic. Biol. Med.
, vol.26
, pp. 1418-1426
-
-
Tirosh, O.1
Sen, C.K.2
Roy, S.3
Kobayashi, M.S.4
Packer, L.5
-
27
-
-
0028998329
-
Insulin-mediated activation of glycogen synthase in isolated skeletal muscle: Role of mitochondrial respiration
-
Katz, A. & Westerblad, H. (1995) Insulin-mediated activation of glycogen synthase in isolated skeletal muscle: role of mitochondrial respiration. Biochim. Biophys. Acta 1244: 229-232.
-
(1995)
Biochim. Biophys. Acta
, vol.1244
, pp. 229-232
-
-
Katz, A.1
Westerblad, H.2
-
28
-
-
0029984062
-
Antioxidant and redox regulation of gene transcription
-
Sen, C. K. & Packer, L. (1996) Antioxidant and redox regulation of gene transcription. FASEB J. 10: 709-720.
-
(1996)
FASEB J.
, vol.10
, pp. 709-720
-
-
Sen, C.K.1
Packer, L.2
-
29
-
-
0032100603
-
Redox signaling and the emerging therapeutic potential of thiol antioxidants
-
Sen, C. K. (1998) Redox signaling and the emerging therapeutic potential of thiol antioxidants. Biochem. Pharmacol. 55: 1747-1758.
-
(1998)
Biochem. Pharmacol.
, vol.55
, pp. 1747-1758
-
-
Sen, C.K.1
-
30
-
-
0032799487
-
Lipoic acid protects against oxidative stress induced impairment in insulin stimulation of protein kinase B and glucose transport in 3T3-L1 adipocytes
-
Rudich, A., Tirosh, A., Potashnik, R., Khamaisi, M. & Bashan, N. (1999) Lipoic acid protects against oxidative stress induced impairment in insulin stimulation of protein kinase B and glucose transport in 3T3-L1 adipocytes. Diabetologia 42: 949-957.
-
(1999)
Diabetologia
, vol.42
, pp. 949-957
-
-
Rudich, A.1
Tirosh, A.2
Potashnik, R.3
Khamaisi, M.4
Bashan, N.5
-
31
-
-
0031041060
-
Modulation of cellular reducing equivalent homeostasis by α-lipoic acid. Mechanisms and implications for diabetes and ischemic injury
-
Roy, S., Sen, C. K., Tritschler, H. J. & Packer, L. (1997) Modulation of cellular reducing equivalent homeostasis by α-lipoic acid. Mechanisms and implications for diabetes and ischemic injury. Biochem. Pharmacol. 53: 393-399.
-
(1997)
Biochem. Pharmacol.
, vol.53
, pp. 393-399
-
-
Roy, S.1
Sen, C.K.2
Tritschler, H.J.3
Packer, L.4
-
32
-
-
0033945846
-
Mitochondrial oxidative stress plays a key role in aging and apoptosis
-
Sastre, J., Pallardo, F. V. & Vina, J. (2000) Mitochondrial oxidative stress plays a key role in aging and apoptosis. IUBMB Life 49: 427-435.
-
(2000)
IUBMB Life
, vol.49
, pp. 427-435
-
-
Sastre, J.1
Pallardo, F.V.2
Vina, J.3
-
33
-
-
0034016125
-
Mitochondria, oxidative stress and aging
-
Sastre, J., Pallardo, F. V., Garcia de la Asuncion, J. & Vina, J. (2000) Mitochondria, oxidative stress and aging. Free Radic. Res. 32: 189-198.
-
(2000)
Free Radic. Res.
, vol.32
, pp. 189-198
-
-
Sastre, J.1
Pallardo, F.V.2
Garcia de la Asuncion, J.3
Vina, J.4
-
34
-
-
0031036081
-
Uncoupling effects of diclofenac and aspirin in the perfused liver and isolated hepatic mitochondria of rat
-
Petrescu, I. & Tarba, C. (1997) Uncoupling effects of diclofenac and aspirin in the perfused liver and isolated hepatic mitochondria of rat. Biochim. Biophys. Acta 1318: 385-394.
-
(1997)
Biochim. Biophys. Acta
, vol.1318
, pp. 385-394
-
-
Petrescu, I.1
Tarba, C.2
-
35
-
-
0033796250
-
Mitochondrial free radical generation, oxidative stress, and aging
-
Cadenas, E. & Davies, K. J, (2000) Mitochondrial free radical generation, oxidative stress, and aging. Free Radic. Biol. Med. 29: 222-230.
-
(2000)
Free Radic. Biol. Med.
, vol.29
, pp. 222-230
-
-
Cadenas, E.1
Davies, K.J.2
-
36
-
-
0030761155
-
Mitochondrial membrane potential and hydroethidine-monitored superoxide generation in cultured cerebellar granule cells
-
Budd, S. L., Castilho, R. F. & Nicholls, D. G. (1997) Mitochondrial membrane potential and hydroethidine-monitored superoxide generation in cultured cerebellar granule cells. FEBS Lett. 415: 21-24.
-
(1997)
FEBS Lett.
, vol.415
, pp. 21-24
-
-
Budd, S.L.1
Castilho, R.F.2
Nicholls, D.G.3
-
37
-
-
0015882341
-
The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen
-
Boveris, A. & Chance, B. (1973) The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen. Biochem. J. 134: 707-716.
-
(1973)
Biochem. J.
, vol.134
, pp. 707-716
-
-
Boveris, A.1
Chance, B.2
-
38
-
-
0015363173
-
The cellular production of hydrogen peroxide
-
Boveris, A., Oshino, N. & Chance, B. (1972) The cellular production of hydrogen peroxide. Biochem. J. 128: 617-630.
-
(1972)
Biochem. J.
, vol.128
, pp. 617-630
-
-
Boveris, A.1
Oshino, N.2
Chance, B.3
|