Early downregulation of IGF-I decides the fate of rat retinal ganglion cells after optic nerve injury

Neurochemistry International

Volumn 50, Issue 5, 2007, Pages 741-748

  Homma, Keiko ^a   Koriyama, Yoshiki ^a,c   Mawatari, Kazuhiro ^a   Higuchi, Yoshihiro ^a   Kosaka, Jun ^b   Kato, Satoru ^a,c  

^a KANAZAWA UNIVERSITY   (Japan)

^b OKAYAMA UNIVERSITY   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Apoptosis; IGF I; Optic nerve regeneration; p Akt; Rat; Retina; Retinal ganglion cells

Indexed keywords

CASPASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BAD; PROTEIN BAX; PROTEIN KINASE B; SOMATOMEDIN C; WORTMANNIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DEATH; CELL SURVIVAL; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; NERVE CRUSH; NERVE FIBER GROWTH; NEUROCHEMISTRY; NEUROPATHOLOGY; NONHUMAN; OPTIC NERVE INJURY; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; RETINA GANGLION CELL; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; APOPTOSIS; AXONS; CASPASE 3; DOWN-REGULATION; INSULIN-LIKE GROWTH FACTOR I; NERVE CRUSH; OPTIC NERVE INJURIES; RATS; RATS, SPRAGUE-DAWLEY; RETINAL GANGLION CELLS; SIGNAL TRANSDUCTION;

RATTUS;

EID: 33947358634     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuint.2007.01.011     Document Type: Article

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